Correlation between serum tryptase, mast cells positive to tryptase and microvascular density in colo-rectal cancer patients: Possible biological-clinical significance

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Ammendola, Michele ^a,b   Sacco, Rosario ^a   Sammarco, Giuseppe ^a   Donato, Giuseppe ^a   Montemurro, Severino ^b   Ruggieri, Eustachio ^b   Patruno, Rosa ^c   Marech, Ilaria ^b   Cariello, Marica ^b   Vacca, Angelo ^d   Gadaleta, Cosmo Damiano ^b   Ranieri, Girolamo ^b  

^a UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^b NATIONAL CANCER INSTITUTE GIOVANNI PAOLO II   (Italy)

^c Department of Health ASL BAT   (Italy)

^d UNIVERSITY OF BARI MEDICAL SCHOOL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

TRYPTASE; VASCULOTROPIN A;

ARTICLE; BLOOD SAMPLING; CAPILLARY DENSITY; CELL DENSITY; COLORECTAL CANCER; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME BLOOD LEVEL; ENZYME RELEASE; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; MAST CELL; MOLECULAR PATHOLOGY; TUMOR VASCULARIZATION; BLOOD; COLORECTAL NEOPLASMS; ENZYMOLOGY; INTESTINE MUCOSA; METABOLISM; MICROVASCULATURE; PATHOLOGY; VASCULARIZATION;

COLORECTAL NEOPLASMS; FEMALE; HUMANS; INTESTINAL MUCOSA; MALE; MAST CELLS; MICROVESSELS; TRYPTASES; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84902603135     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0099512     Document Type: Article

References (47)

1. Ranieri G, Labriola A, Achille G, Florio G, Zito AF, et al. (2002) Microvessel density, mast cell density and thymidine phosphorylase expression in oral squamous carcinoma. Int J Oncol 21: 1317-1323.
2. Ranieri G, Ammendola M, Patruno R, Celano G, Zito FA, et al. (2009) Tryptase-positive mast cells correlate with angiogenesis in early breast cancer patients. Int J Oncol 35: 115-120.
3. Weidner N, Semple JP, Welch WR, Folkman J (1991) Tumour angiogenesis and metastasis correlation in invasive breast carcinoma. N Engl J Med 324: 1-8.
4. Kankkunen JP, Harvima IT, Naukkarinen A (1997) Quantitative analysis of tryptase and chymase containing mast cells in benign and malignant breast lesions. Int J Cancer 72: 385-388. (Pubitemid 27325861)
5. Soucek L, Lawlor ER, Soto D, Shchors K, Swigart LB, et al. (2007) Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumours. Nat Med 13: 1211-1218. (Pubitemid 47530639)
6. Ribatti D, Ranieri G, Nico B, Benagiano V, Crivellato E (2011) Tryptase and chymase are angiogenic in vivo in the chorioallantoic membrane assay. Int J Dev Biol 55: 99-102.
7. Mangia A, Malfettone A, Rossi R, Paradiso A, Ranieri G, et al. (2011) Tissue remodelling in breast cancer: human mast cells tryptase as an initiator of myofibroblast differentiation. Histopathology 58: 1096-1106.
8. Ranieri G, Gadaleta-Caldarola G, Goffredo V, Patruno R, Mangia A, et al. (2012) Sorafenib (BAY 43-9006) in hepatocellular carcinoma patients: from discovery to clinical development. Curr Med Chem 19: 938-944.
9. Ranieri G, Gadaleta CD, Patruno R, Zizzo N, Daidone MG, et al. (2013) A model of study for human cancer: Spontaneous occurring tumors in dogs. Biological features and translation for new anticancer therapies. Crit Rev Oncol Hematol 88: 187-197.
10. Ranieri G, Passantino L, Patruno R, Passantino G, Jirillo F, et al. (2003) The dog mast cell tumour as a model to study the relationship between angiogenesis, mast cells density and tumour malignancy. Oncol Rep 10: 1189-1193.
11. Igarashi M, Dhar DK, Kubota H, Yamamoto A, El-Assal O, et al. (1998) The prognostic significance of microvessel density and thymidine phosphorylase expression in squamous cell carcinoma of the esophagus. Cancer 82: 1225-1232. (Pubitemid 28155382)
12. Gulubova M, Vlaykova T (2009) Prognostic significance of mast cell number and microvascular density for the survival of patients with primary colorectal cancer. J Gastroenterol Hepatol 24: 1265-1275.
13. Yano H, Kinuta M, Tateishi H, Nakano Y, Matsui S, et al. (1999) Mast cell infiltration around gastric cancer cells correlates with tumour angiogenesis and metastasis. Gastric Canc 2: 26-32.
14. Polverini PF (1996) How the extracellular matrix and macrophages contribute to angiogenesis-dependent disease. Eur J Cancer 32: 2430-2437.
15. Dethlefsen SM, Matsuura N, Zetter BR (1994) Mast cell accumulation at sites of murine tumor implantation: implications for angiogenesis and tumor metastasis. Invas Met 14: 395-408.
16. Patruno R, Arpaia N, Gadaleta CD, Passantino L, Zizzo N, et al. (2009) VEGF concentration from plasma-activated platelets rich correlates with microvascular density and grading in canine mast cell tumour spontaneous model. J Cell Mol Med 13: 555-561.
17. Elpek GO, Gelen T, Aksoy NH, Erdoǧan A, Dertsiz L, et al. (2001) The prognostic relevance of angiogenesis and mast cells in squamous cell carcinoma of the oesophagus. J Clin Pathol 54: 940-944. (Pubitemid 34032889)
18. Kondo K, Muramatsu M, Okamoto Y, Jin D, Takai S, et al. (2006) Expression of chymase-positive cells in gastric cancer and its correlation with the angiogenesis. J Surg Oncol 93: 36-42. (Pubitemid 43038424)
19. Takanami I, Takeuchi K, Naruke M (2000) Mast cell density is associated with angiogenesis and poor prognosis in pulmonary adenocarcinoma. Cancer 88: 2686-2692. (Pubitemid 30417928)
20. Ch'ng S, Wallis RA, Yuan L, Davis PF, Tan ST (2006) Mast cells and cutaneous malignancies. Mod Pathol 19: 149-159. (Pubitemid 43250990)
21. Hallgren J, Pejler G (2006) Biology of mast cell tryptase: an inflammatory mediator. FEBS J 25: 234-241.
22. Schwartz LB, Yunginger JW, Miller J, Bokhari R, Dull D (1989) Time course of appearance and disappearance of human mast cell tryptase in the circulation after anaphylaxis. J Clin Invest 83: 1551-1555. (Pubitemid 19124110)
23. Bellone G, Silvestri S, Artusio E, Tibaudi D, Turletti A, et al. (1997) Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-beta 1. J Cell Physiol 172: 1-11. (Pubitemid 27283342)
24. Bellone G, Carbone A, Sibona N, Bosco O, Tibaudi D, et al. (2001) Aberrant activation of c-kit protects colon carcinoma cells against apoptosis and enhances their invasive potential. Cancer Res 61: 2200-2206. (Pubitemid 32692048)
25. Tonnesen MG, Gruber BL (1997) Tryptase is a novel, potent angiogenic factor. J Clin Invest 99: 2691-2700.
26. Ribatti D, Ranieri G, Nico B, Benagiano V, Crivellato E (2011) Tryptase and chymase are angiogenic in vivo in the chorioallantoic membrane assay. Int J Dev Biol 55: 99-102.
27. Attoub S, Rivat C, Rodrigues S, Van Bocxlaer S, Bedin M, et al. (2002) The c-kit tyrosine kinase inhibitor STI571 for colorectal cancer therapy. Cancer Res 62: 4879-4883. (Pubitemid 34984407)
28. Nakashima M, Akiyoshi T, Ueno M, Fukunaga Y, Nagayama S, et al. (2011) Colon cancer in the splenic flexure: comparison of short-term outcomes of laparoscopic and open colectomy. Surg Laparosc Endosc Percutan Tech 21: 415-418.
29. Khan JS, Hemandas AK, Flashman KG, Senapati A, O'Leary D, et al. (2011) Clinical outcome of laparoscopic and open colectomy for right colonic carcinoma. Ann R Coll Surg Engl 93: 603-607.
30. Garlipp B, Ptok H, Schmidt U, Stübs P, Scheidbach H, et al. (2012) Factors influencing the quality of total mesorectal excision. Br J Surg 99: 714-720.
31. Angenete E, Correa-Marinez A, Heath J, González E, Wedin A, et al. (2012) Ostomy function after abdominoperineal resection-a clinical and patient evaluation. Int J Colorectal Dis 27: 1267-1274.
32. Astler VB, Coller FA (1954) The prognostic significance of direct extension of carcinoma of the colon and rectum. Ann Surg 139: 846-852.
33. Ratto C, Ricci (2011) Potential pitfalls concerning colorectal cancer classification in the seventh edition of the AJCC Cancer Staging Manual. Dis Colon Rectum 54: e232.
34. Ranieri G, Grammatica L, Patruno R, Zito AF, Valerio P, et al. (2007) A possible role of thymidine phosphorylase expression and 5-fluorouracil increased sensitivity in oropharyngeal cancer patients. J Cell Mol Med 11: 362-368. (Pubitemid 46693334)
35. Ranieri G, Achille G, Florio G, Labriola A, Marzullo F, et al. (2001) Biological-clinical significance of angiogenesis and mast cell infiltration in squamous cell carcinoma of the oral cavity. Acta Otorhinolaryngol Ital 21: 171-178.
36. Takahashi Y, Kitadai Y, Bucana CD, Cleary KR, Ellis LM (1995) Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer. Cancer Res 55: 3964-3968.
37. Ranieri G, Coviello M, Patruno R, Valerio P, Martino D, et al. (2004) Vascular endothelial growth factor concentrations in the plasma-activated platelets rich (P-APR) of healthy controls and colorectal cancer patients. Oncol Rep 12: 817-820.
38. Ranieri G, Coviello M, Chiriatti A, Stea B, Montemurro S, et al. (2004) Vascular endothelial growth factor assessment in different blood fractions of gastrointestinal cancer patients and healthy controls. Oncol Rep 11: 435-439.
39. Ribatti D, Vacca A, Nico B, Quondamatteo F, Ria R, et al. (1999) Bone marrow angiogenesis and mast cell density increase simultaneously with progression of human multiple myeloma. Br J Cancer 79: 451-455. (Pubitemid 29046218)
40. Patruno R, Marech I, Zizzo N, Ammendola M, Nardulli P, et al. (2014) C-Kit Expression, Angiogenesis, and Grading in Canine Mast Cell Tumour: A Unique Model to Study C-Kit Driven Human Malignancies. BioMed Res Int 2014: ID 730246.
41. Ammendola M, Zuccalà V, Patruno R, Russo E, Luposella M, et al. (2013) Tryptase-positive mast cells and angiogenesis in keloids: a new possible post-surgical target for prevention. Updates Surg 65: 53-57.
42. Ammendola M, Sacco R, Donato G, Zuccalà V, Russo E, et al. (2013) Mast Cell positive to tryptase correlates with metastatic lymph nodes in gastrointestinal cancers patients surgically treated. Oncology 85: 111-116.
43. Ammendola M, Sacco R, Sammarco G, Donato G, Zuccalà V, et al. (2013) Mast cells positive to tryptase and c-Kit receptor expressing cells correlates with angiogenesis in gastric cancer patients surgically treated. Gastroenterol Res Pract 2013: ID 703163.
44. Liu Y, Mueller BM (2006) Protease-activate receptor-2 regulates vascular endothelial growth factor expression in MDA-MB-231cells via MAPK pathways. Biochem Biophys Res Commun 344: 1263-1270.
45. Nico B, Mangieri D, Crivellato E, Vacca A, Ribatti D (2008) Mast cells contribute to vasculogenic mimicry in multiple myeloma. Stem Cells Dev 17: 19-22. (Pubitemid 351271616)
46. Hallegren J, Estrada S, Karlson U, Alving K, Pejler G (2001) Heparin antagonists are potent inhibitors of mast cell tryptase. Biochemistry 40: 7342-7439.
47. Fajardo I, Pejler G (2003) Human mast cell beta-tryptase is a gelatinase. J Immunl 171: 1492-1499.