Growth stimulation of colorectal carcinoma cells via the c-kit receptor is inhibited by TGF-β1

Journal of Cellular Physiology

Volumn 172, Issue 1, 1997, Pages 1-11

  Bellone, Graziella ^a   Silvestri, Stefania ^a   Artusio, Elisa ^a   Tibaudi, Daniela ^a   Turletti, Anna ^a   Geuna, Massimo ^a   Giachino, Claudia ^a   Valente, Guido ^a   Emanuelli, Giorgio ^a   Rodeck, Ulrich ^b  

^a UNIVERSITY OF TURIN   (Italy)

^b WISTAR INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CANCER GROWTH; CELL PROLIFERATION; COLORECTAL CARCINOMA; GROWTH REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ADULT; AGED; CARCINOMA; CELL ADHESION; CELL DIVISION; COLORECTAL NEOPLASMS; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTESTINAL MUCOSA; MALE; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-KIT; RNA, MESSENGER; RNA, NEOPLASM; STEM CELL FACTOR; TRANSFORMING GROWTH FACTOR BETA;

EID: 17144470837     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-4652(199707)172:1<1::AID-JCP1>3.0.CO;2-S     Document Type: Article

References (37)

1. Abe, M., Harpel, J.G., Metz, C.N., Nunes, I., Loskutoff, D.J., and Rifkin, D.B. (1994) An assay for transforming growth factor-β using cells transfected with a plasminogen activator inhibitor-1 promoter-luciferase construct. Anal. Biochem., 216:276-284.
2. Alexander, W.S., Lyman, S.D., and Wagner, E.F. (1991) Expression of functional c-kit receptors rescues the genetic defect of W mutant mast cells. EMBO J., 10:3683-3691.
3. Berdel, W. E., de Vos, S., Maurer, J., Oberberg, D., von Marschall, Z., Schroeder, J.K., Li, J., Ludwig, W.D., Kreuser, E.D., and Thiel, E. (1992) Recombinant human stem cell factor stimulates growth of a human glioblastoma cell line expressing c-kit protooncogene. Cancer Res., 52:3498-3502.
4. Besmer, P., Murphy, J.E., George, P.C., Qiu, F.H., Bergold, P.J., Lederman, L., Snyder, H., Jr., Brodeur, D., Zuckerman, E.E., and Hardy, W.D. (1986) A new acute transforming feline retrovirus and relationship of its oncogene v-kit with the protein kinase gene family. Nature, 320:415-421.
5. Cohen, P.S., Chan, J.P., Lipkunskaya, M., Biedler, J.L., and Seeger, R.C. (1994) Expression of stem cell factor and c-kit in human neuroblastoma The Children's Cancer Group. Blood, 84:3465-3472.
6. de Vos, S., Brach, M.A., Asano, Y., Ludwig, W.D., Bettelheim, P., Gruss, H.J., and Herrmann, F. (1993) Transforming growth factor-beta 1 interferes with the proliferation-inducing activity of stem cell factor in myelogenous leukemia blasts through functional down-regulation of the c-kit proto-oncogene product. Cancer Res., 53:3638-3642.
7. Derynck, R., Goeddel, D.V., Ullrich, A., Gutterman, J.U., Williams, R.D., Bringman, T.S., and Berger, W.H. (1987) Synthesis of messenger RNAs for transforming growth factors alpha and beta and the epidermal growth factor receptor by human tumors. Cancer Res., 47:707-712.
8. Dubois, C.M., Ruscetti, F.W., Stankova, J., and Keller, J.R. (1994) Transforming growth factor-beta regulates c-kit message stability and cell-surface protein expression in hematopoietic progenitors. Blood, 83:3138-3145.
9. Flanagan, J.G., and Leder, P. (1990) The kit ligand: a cell surface molecule altered in steel mutant fibroblasts. Cell, 63:185-194.
10. Franzen, P., ten Dijke, P., Ichijo, H., Yamashita, H., Schulz, P., Heldin, C.H., and Miyazono, K. (1993) Cloning of a TGF beta type I receptor that forms a heteromeric complex with the TGF beta type II receptor. Cell, 75:681-692.
11. Galli, S.J., Zsebo, K.M., and Geissler, E.N. (1994) The kit ligand, stem cell factor. Adv. Immunol., 55:1-96.
12. Heinrich, M.C., Dooley, D.C., and Keeble, W.W. (1995) Transforming growth factor beta 1 inhibits expression of the gene products for steel factor and its receptor (c-kit). Blood, 85:1769-1780.
13. Hibi, K., Takahashi, T., Sekido, Y., Ueda, R., Hida, T., Ariyoshi, Y., Takagi, H., and Takahashi, T. (1991) Coexpression of the stem cell factor and the c-kit genes in small-cell lung cancer. Oncogene, 6:2291-2296.
14. Hines, S.J., Organ, C., Kornstein, M.J., and Krystal, G.W. (1995) Coexpression of the c-kit and stem cell factor genes in breast carcinomas. Cell Growth Differ., 6:769-779.
15. Hsu, S.M., Rami, L., and Fanger, H. (1991) Use of avidin biotin peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) techniques. J. Histochem. Cytochem., 29:577-580.
16. Huang, E., Nocka, K., Beier, D.R., Chu, T.Y., Buck, J., Lahm, H.W., Wellner, D., Leder, P., and Besmer, P. (1990) The hematopoietic growth factor KL is encoded by the Sl locus and is the ligand of the c-kit receptor, the gene product of the W locus. Cell, 63:225-233.
17. Ida, J., Jr., Dubois-Dalcq, M., and McKinnon, R.D. (1993) Expression of the receptor tyrosine kinase c-kit in oligodendrocyte progenitor cells. J. Neurosci. Res., 36:596-606.
18. Inoue, M., Kyo, S., Fujita, M., Enomoto, T., and Kondoh, G. (1994) Coexpression of the c-kit receptor and the stem cell factor in gynecological tumors. Cancer Res., 54:3049-3053.
19. Keeton, M.R., Curriden, S.A., van Zonneveld, A.J., and Loskutoff, D.J. (1991) Identification of regulatory sequences in the type 1 plasminogen activator inhibitor gene responsive to transforming growth factor beta. J. Biol. Chem., 266:23048-23052.
20. Khoury, E., Andre, C., Pontvert-Delucq, S., Drenou, B., Baillou, C., Guigon, M., Najman, A., and Lemoine, F.M. (1994) Tumor necrosis factor alpha downregulates c-kit proto-oncogene product expression in normal and acute myeloid leukemia CD34+ cells via p55 TNF alpha receptors. Blood, 84:2506-2514.
21. Lahm, H., Amstad, P., Yilmaz, A., Borbenyi, Z., Wyniger, J., Fischer, J.R., Suardet, L., Givel, J.C., and Odartchenko, N. (1995) Interleukin 4 down-regulates expression of c-kit and autocrine stem cell factor in human colorectal carcinoma cells. Cell Growth Differ., 6:1111-1118.
22. Lassam, N., and Bickford, S. (1992) Loss of c-kit expression in cultured melanoma cells. Oncogene, 7:51-56.
23. Lin, H.Y., Wang, X.-F., Ng-Eaton, E., Weinberg, R.A., and Lodish, H.F. (1992) Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. Cell, 68:775-785.
24. Manova, K., Bachvarova, R.F., Huang, E.J., Sanchez, S., Pronovost, S.M., Velazquez, E., McGuire, B., and Besmer, P. (1992) c-kit receptor and ligand expression in postnatal development of the mouse cerebellum suggests a function for c-kit in inhibitory interneurons. J. Neurosci., 12:4663-4676.
25. Matsuda, R., Takahashi, T., Nakamura, S., Sekido, Y., Nishida, K., Seto, M., Seito, T., Sugiura, T., Ariyoshi, Y., and Takahashi, T. (1993) Expression of the c-kit protein in human solid tumors and in corresponding fetal and adult normal tissues. Am. J. Pathol., 142:339-346.
26. Remmele, W., and Stegner, H.E. (1986) Immunohistochemischer Nachweis von Östrogenrezeptoren (ERICA) im Mammakarzinomgewebe: Vorschlag zur einheitlichen Formulierung des Untersuchungsbefundes. Dtsch. Ärztebl., 83:3362-3364.
27. Sekido, Y., Obata, Y., Ueda, R., Hida, T., Suyama, M., Shimokata, K., Ariyoshi, Y., and Takahashi, T. (1991) Preferential expression of c-kit protooncogene transcripts in small cell lung cancer. Cancer Res., 51:2416-2419.
28. Strohmeyer, T., Peter, S., Hartmann, M., Munemitsu, S., Ackermann, R., Ullrich, A., and Slamon, D.J. (1991) Expression of the hst-1 and c-kit protooncogenes in human testicular germ cell tumors. Cancer Res., 51:1811-1816.
29. Topalian, S.L., Muul, L.M., Solomon, D., and Rosenberg, S.A. (1987) Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials. J. Immunol. Methods, 102:127-141.
30. Toyota, M., Hinoda, Y., Takaoka, A., Makiguchi, Y., Takahashi, T., Itoh, F., Imai, K., and Yachi, A. (1993) Expression of c-kit and kit ligand in human colon carcinoma cells. Tumour Biol., 14:295-302.
31. Turner, A.M., Zsebo, K.M., Martin, F., Jacobsen, F.W., Bennett, L.G., and Broudy, V.C. (1992) Nonhematopoietic tumor cell lines express stem cell factor and display c-kit receptors. Blood, 80:374-381.
32. Ullrich, A., and Schlessinger, J. (1990) Signal transduction by receptors with tyrosine kinase activity. Cell, 61:203-212.
33. Wang, X.F., Lin, H.Y., Ng-Eaton, E., Downward, J., Lodish, H.F., and Weinberg, R.A. (1991) Expression cloning and characterization of the TGF-beta type III receptor. Cell, 67:797-805.
34. Williams, D.E., Eisenman, J., Baird, A., Rauch, C., Van Ness, K., March, C.J., Park, L.S., Martin, U., Mochizuki, D.Y., and Boswell, H.S. (1990) Identification of a ligand for the c-kit proto-oncogene. Cell, 63:167-174.
35. Witte, O.N. (1990) Steel locus defines new multipotent growth factor [published erratum appears in Cell 1990 Nov 30; 63(5): following 1112]. Cell, 63:5-6.
36. Yarden, Y., Kuang, W.J., Yang-Feng, T., Coussens, L., Munemitsu, S., Dull, T.J., Chen, E., Schlessinger, J., Francke, U., and Ullrich, A. (1987) Human proto-oncogene c-kit: a new cell surface receptor tyrosine kinase for an unidentified ligand. EMBO J., 6:3341-3351.
37. Zsebo, K.M., Williams, D.A., Geissler, E.N., Broudy, V.C., Martin, F.H., Atkins, H.L., Hsu, R.Y., Birkett, N.C., Okino, K.H., and Murdock, D.C. (1990) Stem cell factor is encoded at the Sl locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell, 63:213-224.