Microparticle-associated tissue factor activity is reduced by inhibition of the complement protein 5 in Neisseria meningitidis-exposed whole blood

Innate Immunity

Volumn 20, Issue 5, 2014, Pages 552-560

  Øvstebø, Reidun ^a   Hellum, Marit ^a,c   Aass, Hans Christian D ^a   Trøseid, Anne M ^a   Brandtzaeg, Petter ^b,c   Mollnes, Tom E ^b,c   Henriksson, Carola E ^a  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^b OSLO UNIVERSITY HOSPITAL   (Norway)

^c UNIVERSITY OF OSLO   (Norway)

Author keywords

coagulation cascade; complement cascade; microparticles; monocytes; Neisseria meningitidis; TF activity

Indexed keywords

ANTICOAGULANT AGENT; CITRIC ACID; COMPLEMENT COMPONENT C5; ECULIZUMAB; FIBRIN; LEPIRUDIN; MESSENGER RNA; MONOCLONAL ANTIBODY; THROMBOPLASTIN; HIRUDIN DERIVATIVE; RECOMBINANT PROTEIN;

ARTICLE; ASSAY; BLOOD CLOTTING; CALIBRATED AUTOMATED THROMBOGRAM; CALIBRATION; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM; CONTROLLED STUDY; FIBRIN GENERATION ASSAY; FLOW CYTOMETRY; FLUORESCENCE; GRAM NEGATIVE BACTERIUM; GRAM NEGATIVE SEPSIS; HUMAN; HUMAN CELL; LEUKOCYTE MICROPARTICLE; MENINGOCOCCEMIA; MONOCYTE; NEISSERIA MENINGITIDIS; NONHUMAN; PLASMA; POOLED NORMAL PLASMA; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; ROTATIONAL THROMBOELASTOMETRY; THROMBOCYTE FUNCTION; THROMBOELASTOGRAPHY; ANTAGONISTS AND INHIBITORS; BLOOD; DRUG EFFECTS; IMMUNOLOGY; MEMBRANE MICROPARTICLE; MENINGOCOCCOSIS; METABOLISM; MICROBIOLOGY; SEPSIS; THROMBOCYTE;

ANTIBODIES, MONOCLONAL, HUMANIZED; ANTICOAGULANTS; BLOOD COAGULATION; BLOOD PLATELETS; CELL-DERIVED MICROPARTICLES; COMPLEMENT ACTIVATION; COMPLEMENT C5; HIRUDINS; HUMANS; MENINGOCOCCAL INFECTIONS; NEISSERIA MENINGITIDIS; RECOMBINANT PROTEINS; SEPSIS; THROMBOPLASTIN;

EID: 84902598788     PISSN: 17534259     EISSN: 17534267     Source Type: Journal    
DOI: 10.1177/1753425913502099     Document Type: Article

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