Analysis of Familial Hemophagocytic Lymphohistiocytosis type 4 (FHL-4) mutant proteins reveals that S-acylation is required for the function of syntaxin 11 in natural killer cells

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Hellewell, Andrew L ^a,b   Foresti, Ombretta ^a,c   Gover, Nicola ^a   Porter, Morwenna Y ^a   Hewitt, Eric W ^a  

^a UNIVERSITY OF LEEDS   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

^c CENTRE FOR GENOMIC REGULATION CRG   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; MUNC18 PROTEIN; MUNC18-2 PROTEIN; SYNAPTOSOMAL ASSOCIATED PROTEIN 23; SYNTAXIN; SYNTAXIN 11; UNCLASSIFIED DRUG; MUTANT PROTEIN; QB SNARE PROTEIN; QC SNARE PROTEIN; SNAP23 PROTEIN, HUMAN;

ACYLATION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DELETION MUTANT; FHL4 GENE; FRAMESHIFT MUTATION; GENE; HEMOPHAGOCYTIC SYNDROME; HUMAN; HUMAN CELL; IMMUNOLOGICAL SYNAPSE; INTRACELLULAR MEMBRANE; NATURAL KILLER CELL; POLARIZATION; PROTEIN ANALYSIS; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; CHEMISTRY; CYTOLOGY; GENETICS; HELA CELL LINE; IMMUNOLOGY; METABOLISM; NUCLEOTIDE SEQUENCE;

ACYLATION; BASE SEQUENCE; CYSTEINE; HELA CELLS; HUMANS; IMMUNOLOGICAL SYNAPSES; INTRACELLULAR MEMBRANES; KILLER CELLS, NATURAL; LYMPHOHISTIOCYTOSIS, HEMOPHAGOCYTIC; MUTANT PROTEINS; QA-SNARE PROTEINS; QB-SNARE PROTEINS; QC-SNARE PROTEINS;

EID: 84902588467     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0098900     Document Type: Article

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