Stage-specific roles for Cxcr4 signaling in murine hematopoietic stem/progenitor cells in the process of bone marrow repopulation

Stem Cells

Volumn 32, Issue 7, 2014, Pages 1929-1942

  Lai, Chen Yi ^a   Yamazaki, Satoshi ^a   Okabe, Motohito ^a   Suzuki, Sachie ^a   Maeyama, Yoshihiro ^b   Iimura, Yasuaki ^c   Onodera, Masafumi ^d   Kakuta, Shigeru ^a,e   Iwakura, Yoichiro ^a,f   Nojima, Masanori ^a   Otsu, Makoto ^a   Nakauchi, Hiromitsu ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b HYOGO COLLEGE OF MEDICINE   (Japan)

^c Kushiro City General Hospital   (Japan)

^d NATIONAL RESEARCH INSTITUTE FOR CHILD HEALTH AND DEVELOPMENT   (Japan)

^e UNIVERSITY OF TOKYO   (Japan)

^f TOKYO UNIVERSITY OF SCIENCE   (Japan)

Author keywords

Chemokine receptors; Gene therapy (gene transfer to hematopoietic stem cells); Hematopoietic stem cells (stem and primitive progenitor cells); Stem cell transplantation

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; MITOGEN ACTIVATED PROTEIN KINASE; CXCR4 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BLOOD; BONE MARROW; BONE MARROW REPOPULATION; CARBOXY TERMINAL SEQUENCE; CELL HOMING; CELL LODGING; CELL MIGRATION; CELL POPULATION; COCULTURE; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; GAIN OF FUNCTION MUTATION; GENE OVEREXPRESSION; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; LOSS OF FUNCTION MUTATION; MICROENVIRONMENT; MOUSE; NONHUMAN; POPULATION DYNAMICS; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; STROMA CELL; WILD TYPE; ANIMAL; BONE MARROW DISEASES; C57BL MOUSE; CELL CULTURE; CELL MOTION; CELL PROLIFERATION; HEMATOPOIETIC STEM CELL TRANSPLANTATION; KNOCKOUT MOUSE; METABOLISM; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PROTEIN PROCESSING; REGENERATION;

ANIMALS; BONE MARROW; BONE MARROW DISEASES; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; COCULTURE TECHNIQUES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HEMATOPOIETIC STEM CELLS; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECEPTORS, CXCR4; REGENERATION; SIGNAL TRANSDUCTION;

EID: 84902583084     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1670     Document Type: Article

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