Evaluation of Pre-analytical Variables in a Commercial Thrombin Generation Assay

Thrombosis Research

Volumn 134, Issue 1, 2014, Pages 160-164

  Rodgers, Susan E ^a,b   Wong, Amanda ^b   Gopal, Reanuga D ^a   Dale, Brian J ^b   Duncan, Elizabeth M ^a   McRae, Simon J ^a,b  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

blood coagulation tests; centrifugation; corn trypsin inhibitor; thrombin generation assay; time factors

Indexed keywords

BLOOD CLOTTING FACTOR 8; THROMBIN; THROMBOPLASTIN; TRYPSIN INHIBITOR;

ARTICLE; BLOOD CLOTTING TEST; BLOOD SAMPLING; CALIBRATED AUTOMATED THROMBOGRAPHY; CENTRIFUGATION; CONTROLLED STUDY; FILTRATION; HUMAN; PARTIAL THROMBOPLASTIN TIME; PLASMA; PRIORITY JOURNAL; THROMBIN GENERATION ASSAY; THROMBOCYTE COUNT; THROMBOCYTE POOR PLASMA; BIOSYNTHESIS; PROCEDURES;

BLOOD COAGULATION TESTS; CENTRIFUGATION; HUMANS; THROMBIN; THROMBOPLASTIN;

EID: 84902551577     PISSN: 00493848     EISSN: 18792472     Source Type: Journal    
DOI: 10.1016/j.thromres.2014.04.010     Document Type: Article

References (15)

1. K.E. Brummel, S.G. Paradis, S. Butenas, and K.G. Mann Thrombin functions during tissue-factor induced blood coagulation Blood 100 2002 148 152
2. T. Baglin The measurement and application of thrombin generation Br J Haematol 130 2005 653 661
3. H.C. Hemker, P. Giesen, R. Al Dieri, V. Regnault, E. de Smedt, and R. Wagenvoord et al. Calibrated automated thrombin generation measurement in clotting plasma Pathophysiol Haemost Thromb 33 2003 4 15
4. G.T. Gerotziafas, F. Depasse, J. Busson, L. Leflem, I. Elamy, and M.M. Samama Towards a standardization of thrombin generation assessment: The influence of tissue factor, platelets and phospholipids concentration on the normal values of Thrombogram-Thrombinoscope assay Thromb J 3 2005 16 26
5. Y. Dargaud, R. Luddington, E. Gray, C. Negrier, T. Lecompte, and S. Petros et al. Effect of standardization and normalization on imprecision of calibrated automated thrombography: an international multicentre study Br J Haematol 139 2007 303 309
6. Y. Dargaud, R. Luddington, E. Gray, T. Lecompte, T. Siegemund, and T. Baglin et al. Standardisation of thrombin generation test - which reference plasma for TGT?: An international multicentre study Thromb Res 125 2010 353 356
7. Y. Dargaud, A.S. Wolberg, R. Luddington, V. Regnault, H. Spronk, and T. Baglin et al. Evaluation of a standardized protocol for thrombin generation measurement using the calibrated automated thrombogram: An international multicentre study Thromb Res 130 2012 929 934
8. Y. Dargaud, S. Beguin, A. Lienhart, R. Al Dieri, C. Trzeciak, and J.C. Bordet et al. Evaluation of thrombin generating capacity in plasma from patients with haemophilia A and B Thromb Haemost 93 2005 475 480
9. V. Chantarangkul, M. Clerici, C. Bressi, P.L.A. Giesen, and A. Tripodi Thrombin generation assessed as endogenous thrombin potential in patients with hyper- or hypo-coagulability Haematologica 88 2003 547 554
10. R. Loeffen, M.C. Kleinegris, S.T. Loubele, P.H. Pluijmen, D. Fens, and R. van Oerle et al. Pre-analytical variables of thrombin generation: towards a standard procedure and validation of the method J Thromb Haemost 10 2012 2544 2554
11. E.J. Favaloro, A. Mohammed, R. Coombs, and P.A. Mehrabani Filtered plasma as a potential cause of clinical misdiagnosis: inappropriate testing in a haematology laboratory Br J Biomed Sci 52 1995 243 248
12. C.A. Sheppard, C. Channell, J.C. Ritchie, and A. Duncan Preanalytical variables in coagulation testing Blood Coagul Fibrinolysis 17 2006 425 426
13. R. Luddington, and T. Baglin Clinical measurement of thrombin generation by calibrated automated thrombography requires contact factor inhibition J Thromb Haemost 2 2004 1954 1959
14. J.J. van Veen, A. Gatt, P.C. Cooper, S. Kitchen, A.E. Bowyer, and M. Makris Corn trypsin inhibitor in Fluorogenic thrombin generation measurements is only necessary at low tissue factor concentrations and influences the relationship between FVIII:C and thrombogram parameters Blood Coagul Fibrinolysis 19 2008 183 189
15. H.M.H. Spronk, A.W.J.H. Dielis, M. Panova-Noeva, R. van Oerle, D. Fens, and M.H. Prins et al. Monitoring thrombin generation: Is addition of corn trypsin inhibitor needed? Thromb Haemost 101 2009 1156 1162