Differentiation of iPSCs into insulin-producing cells via adenoviral transfection of PDX-1, NeuroD1 and MafA

Diabetes Research and Clinical Practice

Volumn 104, Issue 3, 2014, Pages 383-392

  Wang, Lei ^a   Huang, Yan ^a   Guo, Qingsong ^a   Fan, Xiangjun ^a   Lu, Yuhua ^a   Zhu, Shajun ^a   Wang, Yao ^a   Bo, Xiangkun ^a   Chang, Xu ^a   Zhu, Mingyan ^a   Wang, Zhiwei ^a  

^a NANTONG UNIVERSITY   (China)

Author keywords

Insulin; IPSCs; Transgenes; Transplantation; Cell

Indexed keywords

ADENOVIRUS VECTOR; GLUCOSE; GREEN FLUORESCENT PROTEIN; INSULIN; NEUROGENIC DIFFERENTIATION FACTOR; TRANSCRIPTION FACTOR MAFA; TRANSCRIPTION FACTOR PDX 1;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FUNCTION; CELL STIMULATION; CELL TRANSPLANTATION; CONTROLLED STUDY; DNA MODIFICATION; EMBRYO; EMBRYOID BODY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; GENETIC TRANSFECTION; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN PRODUCING CELL; INSULIN RELEASE; INSULIN SYNTHESIS; INTRAPERITONEAL GLUCOSE TOLERANCE TEST; LIVER PARENCHYMA; MOUSE; NONHUMAN; PANCREAS CELL; PLURIPOTENT STEM CELL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECRETORY CELL; TISSUE ENGINEERING;

INSULIN; IPSCS; TRANSGENES; TRANSPLANTATION; Β CELL;

ADENOVIRIDAE; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BLOOD GLUCOSE; BLOTTING, WESTERN; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; HOMEODOMAIN PROTEINS; INDUCED PLURIPOTENT STEM CELLS; INSULIN; INSULIN-SECRETING CELLS; MAF TRANSCRIPTION FACTORS, LARGE; MICE; MICE, INBRED C57BL; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANS-ACTIVATORS; TRANSFECTION;

EID: 84902548445     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2014.03.017     Document Type: Article

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