Fetuin-A, a new vascular biomarker of cognitive decline in older adults

Clinical Endocrinology

Volumn 81, Issue 1, 2014, Pages 134-140

  Laughlin, Gail A ^a   McEvoy, Linda K ^b   Barrett Connor, Elizabeth ^a   Daniels, Lori B ^a,c   Ix, Joachim H ^a,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^d VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHYPERTENSIVE AGENT; FETUIN A; BIOLOGICAL MARKER;

ADULT; AGED; ARTHRITIS; ARTICLE; COGNITION; COGNITIVE DEFECT; CONTROLLED STUDY; DEPRESSION; DIABETES MELLITUS; DISEASE ASSOCIATION; EDUCATIONAL STATUS; EMPHYSEMA; FEMALE; FOLLOW UP; HEART DISEASE; HIP FRACTURE; HUMAN; HYPERTENSION; KIDNEY DISEASE; LIVER DISEASE; MAJOR CLINICAL STUDY; MALE; MALIGNANT NEOPLASTIC DISEASE; MINI MENTAL STATE EXAMINATION; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RISK FACTOR; THYROID DISEASE; VASCULAR DISEASE; BLOOD; METABOLISM; MIDDLE AGED; PHYSIOLOGY;

ADULT; AGED; ALPHA-2-HS-GLYCOPROTEIN; BIOLOGICAL MARKERS; COGNITION; COGNITION DISORDERS; FEMALE; HUMANS; MALE; MIDDLE AGED;

EID: 84902544183     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12382     Document Type: Article

References (35)

1. Akinyemi, R., Mukaetova-Ladinska, E., Attems, J., et al,. (2013) Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia. Current Alzheimer Research, 29, 29.
2. Kalaria, R.N., (2010) Vascular basis for brain degeneration: faltering controls and risk factors for dementia. Nutrition Reviews, 68 (Suppl. 2), S74-S87.
3. Stampfer, M.J., (2006) Cardiovascular disease and Alzheimer's disease: common links. Journal of Internal Medicine, 260, 211-223.
4. Veglio, F., Paglieri, C., Rabbia, F., et al,. (2009) Hypertension and cerebrovascular damage. Atherosclerosis, 205, 331-341.
5. Elias, P.K., Elias, M.F., D'Agostino, R.B., et al,. (2005) Serum cholesterol and cognitive performance in the Framingham Heart Study. Psychosomatic Medicine, 67, 24-30.
6. Mori, K., Emoto, M., &, Inaba, M., (2011) Fetuin-A: a multifunctional protein. Recent Patents on Endocrine, Metabolic & Immune Drug Discovery, 5, 124-146.
7. Jahnen-Dechent, W., Heiss, A., Schafer, C., et al,. (2011) Fetuin-A regulation of calcified matrix metabolism. Circulation Research, 108, 1494-1509.
8. Ketteler, M., &, Giachelli, C., (2006) Novel insights into vascular calcification. Kidney International. Supplement, 105, S5-S9.
9. Auberger, P., Falquerho, L., Contreres, J.O., et al,. (1989) Characterization of a natural inhibitor of the insulin receptor tyrosine kinase: cDNA cloning, purification, and anti-mitogenic activity. Cell, 58, 631-640.
10. Jensen, M.K., Bartz, T.M., Mukamal, K.J., et al,. (2013) Fetuin-A, type 2 diabetes, and risk of cardiovascular disease in older adults: the Cardiovascular Health Study. Diabetes Care, 36, 1222-1228
11. Ix, J.H., Barrett-Connor, E., Wassel, C.L., et al,. (2011) The associations of fetuin-A with subclinical cardiovascular disease in community-dwelling persons: the Rancho Bernardo Study. Journal of the American College of Cardiology, 58, 2372-2379.
12. Laughlin, G.A., Cummins, K.M., Wassel, C.L., et al,. (2012) The association of fetuin-A with cardiovascular disease mortality in older community-dwelling adults: the Rancho Bernardo study. Journal of the American College of Cardiology, 59, 1688-1696.
13. Ix, J.H., Wassel, C.L., Kanaya, A.M., et al,. (2008) Fetuin-A and incident diabetes mellitus in older persons. JAMA, 300, 182-188.
14. Stefan, N., Fritsche, A., Weikert, C., et al,. (2008) Plasma fetuin-A levels and the risk of type 2 diabetes. Diabetes, 57, 2762-2767.
15. Laughlin, G.A., Barrett-Connor, E., Cummins, K.M., et al,. (2013) Sex-specific association of fetuin-a with type 2 diabetes in older community-dwelling adults: the Rancho Bernardo Study. Diabetes Care, 36, 1994-2000.
16. Wang, H., &, Sama, A.E., (2012) Anti-inflammatory role of fetuin-A in injury and infection. Current Molecular Medicine, 12, 625-633.
17. Dziegielewska, K.M., Andersen, N.A., &, Saunders, N.R., (1998) Modification of macrophage response to lipopolysaccharide by fetuin. Immunology Letters, 60, 31-35.
18. Ketteler, M., Bongartz, P., Westenfeld, R., et al,. (2003) Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis: a cross-sectional study. Lancet, 361, 827-833.
19. Afsar, C.U., Uzun, H., Yurdakul, S., et al,. (2012) Association of serum fetuin-A levels with heart valve calcification and other biomarkers of inflammation among persons with acute coronary syndrome. Clinical and Investigative Medicine, 35, E206-E215.
20. Wang, H., Li, W., Zhu, S., et al,. (2010) Peripheral administration of fetuin-A attenuates early cerebral ischemic injury in rats. Journal of Cerebral Blood Flow and Metabolism, 30, 493-504.
21. Smith, E.R., Nilforooshan, R., Weaving, G., et al,. (2011) Plasma fetuin-A is associated with the severity of cognitive impairment in mild-to-moderate Alzheimer's disease. Journal of Alzheimer's Disease, 24, 327-333.
22. Laughlin, G.A., Barrett-Connor, E., &, May, S., (2007) Sex-specific determinants of serum adiponectin in older adults: the role of endogenous sex hormones. International Journal of Obesity, 31, 457-465.
23. Tombaugh, T.N., &, McIntyre, N.J., (1992) The mini-mental state examination: a comprehensive review. Journal of the American Geriatrics Society, 40, 922-935.
24. Reitan, R., (1958) Validity of the trail-making test as an indicator of organic brain disease. Perceptual and Motor Skills, 8, 271-276.
25. Borkowski, J.G., Benton, A.L., &, Spreen, O., (1967) Word fluency and brain damage. Neuropsychologia 5, 135-140.
26. Gregg, E.W., Yaffe, K., Cauley, J.A., et al,. (2000) Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Archives of Internal Medicine, 160, 174-180.
27. Hennige, A.M., Staiger, H., Wicke, C., et al,. (2008) Fetuin-A induces cytokine expression and suppresses adiponectin production. PLoS One, 3, e1765.
28. Gangneux, C., Daveau, M., Hiron, M., et al,. (2003) The inflammation-induced down-regulation of plasma Fetuin-A (alpha2HS-Glycoprotein) in liver results from the loss of interaction between long C/EBP isoforms at two neighbouring binding sites. Nucleic Acids Research, 31, 5957-5970.
29. Daveau, M., Christian, D., Julen, N., et al,. (1988) The synthesis of human alpha-2-HS glycoprotein is down-regulated by cytokines in hepatoma HepG2 cells. FEBS Letters, 241, 191-194.
30. Ombrellino, M., Wang, H., Yang, H., et al,. (2001) Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan. Shock, 15, 181-185.
31. Belayev, L., Busto, R., Zhao, W., et al,. (1996) Quantitative evaluation of blood-brain barrier permeability following middle cerebral artery occlusion in rats. Brain Research, 739, 88-96.
32. Tombaugh, T.N., (2005) Test-retest reliable coefficients and 5-year change scores for the MMSE and 3MS. Archives of Clinical Neuropsychology, 20, 485-503.
33. Katzman, R., Brown, T., Thal, L.J., et al,. (1988) Comparison of rate of annual change of mental status score in four independent studies of patients with Alzheimer's disease. Annals of Neurology, 24, 384-389.
34. Anderson, V., Jacobs, R., &, Anderson, P., (2008) Executive Functions and the Frontal Lobes: A Lifespan Perspective. Psychology Press, London, UK.
35. Coffey, C.E., Ratcliff, G., Saxton, J.A., et al,. (2001) Cognitive correlates of human brain aging: a quantitative magnetic resonance imaging investigation. Journal of Neuropsychiatry and Clinical Neurosciences, 13, 471-485.