Association of serum fetuin-A levels with heart valve calcication and other biomarkers of inflammation among persons with acute coronary syndrome

Clinical and Investigative Medicine

Volumn 35, Issue 4, 2012, Pages

  Afsar, Cigdem U ^a   Uzun, Haze ^b   Yurdakul, Selen ^b   Muderrisoglu, Cuneyt ^a   Ergüney, Mecdi ^a   Demir, Bulent ^c   Aslan, Aram ^d   Aral, Hale ^d   Ozyazgan, Sibel ^b  

^a Ministry of Health Istanbul Education and Research Hospital   (Turkey)

^b ISTANBUL UNIVERSITY   (Turkey)

^c Bak rköy Dr Sadi Konuk Education and Reseach Hospital Obstetrics and Gynecology   (Turkey)

^d ISTANBUL UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

AHSG PROTEIN, HUMAN; AUTACOID; BIOLOGICAL MARKER; FETUIN A;

ACUTE CORONARY SYNDROME; ADULT; AGED; ARTICLE; BLOOD; CALCINOSIS; CARDIOMYOPATHY; FEMALE; HEART INFARCTION; HUMAN; INFLAMMATION; MALE; METABOLISM; MIDDLE AGED; VALVULAR HEART DISEASE;

ACUTE CORONARY SYNDROME; ADULT; AGED; AGED, 80 AND OVER; ALPHA-2-HS-GLYCOPROTEIN; BIOLOGICAL MARKERS; CALCINOSIS; CARDIOMYOPATHIES; FEMALE; HEART VALVE DISEASES; HUMANS; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION;

EID: 84867391800     PISSN: 0147958X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (37)

1. D'Cruz IA, Panetta F, Cohen H, Glick G. Submitral calcification or sclerosis in elderly patients, M-mode and two dimensional echocardiography in "mitral anulus calcification". Am J Cardiol 1979, 44, 31-8.
2. Hirschfeld DS, Emilson BB. Echocardiogram in calcified mitral anulus. Am J Cardiol 1975, 36, 354-6.
3. Boon A, Cheriex E, Lodder J, Kessels F. Cardiac valve calcification, characteristics of patients with calcification of the mitral annulus or aortic valve. Heart 1997, 78, 472-4.
4. Savage DD, Garrison RJ, Castelli WP, et al. Prevalence of submitral (anular) calcium and its correlates in a general populationbased sample (the Framingham Study). Am J Cardiol 1983, 51, 1375-8.
5. Iribarren C, Sidney S, Sternfeld B, Browner WS. Calcification of the aortic arch, risk factors and association with coronary heart disease, stroke, and peripheral vascular disease. JAMA 2000, 283, 2810-5.
6. Keelan PC, Bielak LF, Ashai K, et al. Long-term prognostic value of coronary calcification detected by electron-beam computed tomography in patients undergoing coronary angiography. Circulation 2001, 104, 412-7.
7. Heiss A, DuChesne A, Denecke B, et al. Structural basis of calcification inhibition by alpha2-HS glycoprotein/fetuin-A. Formation of colloidal calciprotein particles. J Biol Chem 2003, 278, 13333-41.
8. Hermans MM, Brandenburg V, Ketteler M, et al. Association of Serum Fetuin-A Levels with Mortality in Dialysis Patients. Kidney Int 2005, 67:2295-304.
9. Wang AY, Woo J, Lam CW, et al. Associations of serum fetuin-A with malnutrition, inflammation, atherosclerosis and valvular calcification syndrome and outcome in peritoneal dialysis patients. Nephrol Dial Transplant 2005, 20, 1676-85.
10. Lebreton JP, Joisel F, Raoult JP, et al. Serum concentration of human alpha 2 HS glycoprotein during the inflammatory process, evidence that alpha 2 HS glycoprotein is a negative acutephase reactant. J Clin Invest 1979, 64, 1118-29.
11. Kelly RA, Smith TW. Cytokines and cardiac contractile function. Circulation 1997, 95, 778-81.
12. Ketteler M. Fetuin-A and extraosseous calcification in uremia. Curr Opin Nephrol Hypertens 2005, 14:337-42.
13. Ix JH, Chertow GM, Shlipak MG, Brandenburg VM, Ketteler M, Whooley MA. Association of Fetuin-A With Mitral Annular Calcification and Aortic Stenosis Among Persons With Coronary Heart Disease. Circulation 2007, 19:2533-9.
14. Merx MW, Schafer C, Westenfeld R, et al. Myocardial stiffness, cardiac remodeling, and diastolic dysfunction in calcificationprone fetuin-A-deficient mice. J Am Soc Nephrol 2005, 16:3357-64.
15. Thygesen K, Alpert JS, White HD. Universal definition of myocardial infarction. Circulation. 2007, 116:2634-53.
16. Meltzer RS, Martin RP, Robbins BS, Popp RL. Mitral annular calcification, clinical and echocardiographic features. Acta Cardiol 1980, 35:189-202.
17. Barasch E, Gottdiener JS, Larsen EK, Chaves PH, Newman AB, Manolio TA. Clinical significance of calcification of the fibrous skeleton of the heart and aortosclerosis in community dwelling elderly:the Cardiovascular Health Study (CHS). Am Heart J 2006, 151:39-47.
18. Skjaerpe T, Hegrenaes L, Hatle L. Noninvasive estimation of valve area in patients with aortic stenosis by Doppler ultrasound and two-dimensional echocardiography. Circulation 1985, 72:810-8.
19. Zoghbi WA, Farmer KL, Soto JG, Nelson JG, Quinones MA. Accurate noninvasive quantification of stenotic aortic valve area by Doppler echocardiography. Circulation 1986, 73:452-9.
20. Cowell SJ, Newby DE, Prescott RJ, Bloomfield P, Reid J, Northridge DB, Boon NA. A randomized trial of intensive lipid-lowering therapy in calcific aortic stenosis. N Engl J Med 2005, 352:2389-97.
21. American Heart Association, Heart and Stroke Facts, 1995 Statistical Suppl. Dallas, American Heart Association 1994.
22. Moe SM, Reslerova M, Ketteler M, et al. Role of calcification inhibitors in the pathogenesis of vascular calcification in chronic kidney disease (CKD). Kidney Int 2005, 67:2295-304.
23. Ketteler M, Bongartz P, Westenfeld R, et al. Association of low fetuin-A (AHSG) concentrations in serum with cardiovascular mortality in patients on dialysis, a cross-sectional study. Lancet 2003, 361:827-33.
24. Stenvinkel P, Wang K, Qureshi AR, et al. Low fetuin-A levels are associated with cardiovascular death, impact of variations in the gene encoding fetuin. Kidney Int 2005, 67:2383-92.
25. Abbate A, Bonanno E, Mauriello A, et al. Widespread myocardial inflammation and infarct related artery patency. Circulation 2004, 110:46-50.
26. Kilic T, Ural D, Ural E, et al. Relation between proinfiammatory to anti-inflammatory cytokine ratios and long-term prognosis in patients with non-ST elevation acute coronary syndrome. Heart 2006, 92:1041-6.
27. Wang H, Zhang M, Bianchi M, Sherry B, Sama A, Tracey KJ. Fetuin (alpha2-HS-glycoprotein) opsonizes cationic macrophage deactivating molecules. Proc Natl Acad Sci USA 1998, 95:14429-34.
28. Ombrellino M, Wang H, Yang H, et al. Fetuin, a negative acute phase protein, attenuates TNF synthesis and the innate inflammatory response to carrageenan. Shock 2001, 15:181-5.
29. Ross R. Atherosclerosis-an inflammatory disease. N Engl J Med 1999, 340:115-6.
30. Theroux P, Armstrong PW, Mahaffey KW, Hochman JS, Malloy KJ, Rollins S, et al. Prognostic significance of blood markers of inflammation in patients with ST-segment elevation myocardial infarction undergoing primary angioplasty and effects of pexelizumab, a C5 inhibitor, a substudy of the COMMA trial. Eur Heart J 2005, 26:1964-70.
31. Rittig K, Thamer C, Haupt A, et al. High plasma fetuin-A is associated with increased carotid intima-media thickness in a middleaged population. Atherosclerosis 2009, 207, 341-342.
32. Weikert C, Stefan N, Schulze MB, et al. Plasma fetuin-a levels and the risk of myocardial infarction and ischemic stroke. Circulation. 2008, 118:2555-62.
33. Elabbassi W, Al-Nooryani A. Acute coronary syndrome. An acute inflammatory syndrome. Saudi Med J. 2006, 27:1799-803.
34. Bilgir O, Kebapcilar L, Bilgir F, et al. Decreased serum fetuin-A levels are associated with coronary artery diseases. Intern Med. 2010, 49:1281-5.
35. Basar N, Sen N, Kanat S, et al. Lower fetuin-A predicts angiographic impaired reperfusion and mortality in ST-elevation myocardial infarction. J Investig Med. 2011, 59:816-22.
36. Ahmed K, Jeong MH, Chakraborty R, et al. Prognostic impact of baseline high-sensitivity C-reactive protein in patients with acute myocardial infarction undergoing percutaneous coronary intervention based on body mass index. Korean Circ J. 2012, 42:164-72.
37. Lim P, Collet JP, Moutereau S, et al. Fetuin-A is an independent predictor of death after ST elevation myocardial infarction. Clin Chem 2007, 53:1835-40.