-
2
-
-
40149093414
-
Antiretroviral treatment in pregnancy
-
Stek AM. Antiretroviral treatment in pregnancy. Curr Opin HIV AIDS. 2008;3:155-160.
-
(2008)
Curr Opin HIV AIDS.
, vol.3
, pp. 155-160
-
-
Stek, A.M.1
-
3
-
-
20944443338
-
The safety of antiretroviral drugs in pregnancy
-
Thorne C, Newell ML. The safety of antiretroviral drugs in pregnancy. Expert Opin Drug Saf. 2005;4:323-335.
-
(2005)
Expert Opin Drug Saf.
, vol.4
, pp. 323-335
-
-
Thorne, C.1
Newell, M.L.2
-
4
-
-
4644291083
-
Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy
-
Watts DH, Covington DL, Beckerman K, et al. Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy. Am J Obstet Gynecol. 2004;191:985-992.
-
(2004)
Am J Obstet Gynecol.
, vol.191
, pp. 985-992
-
-
Watts, D.H.1
Covington, D.L.2
Beckerman, K.3
-
5
-
-
0024981025
-
Rise and fall of Western diseases
-
Barker DJ. Rise and fall of Western diseases. Nature. 1989;338:371-372.
-
(1989)
Nature.
, vol.338
, pp. 371-372
-
-
Barker, D.J.1
-
6
-
-
0024469193
-
Weight in infancy and death from ischaemic heart disease
-
Barker DJ, Winter PD, Osmond C, et al. Weight in infancy and death from ischaemic heart disease. Lancet. 1989;2:577-580.
-
(1989)
Lancet.
, vol.2
, pp. 577-580
-
-
Barker, D.J.1
Winter, P.D.2
Osmond, C.3
-
7
-
-
0024230485
-
Morphological aspects of the placenta in HIV pregnancies
-
Jauniaux E, Nessmann C, Imbert MC, et al. Morphological aspects of the placenta in HIV pregnancies. Placenta. 1988;9:633-642.
-
(1988)
Placenta.
, vol.9
, pp. 633-642
-
-
Jauniaux, E.1
Nessmann, C.2
Imbert, M.C.3
-
8
-
-
84869118362
-
Morphologic changes in the placentas of HIV-positive women and their association with degree of immune suppression
-
Vermaak A, Theron GB, Schubert PT, et al. Morphologic changes in the placentas of HIV-positive women and their association with degree of immune suppression. Int J Gynaecol Obstet. 2012;119:239-243.
-
(2012)
Int J Gynaecol Obstet.
, vol.119
, pp. 239-243
-
-
Vermaak, A.1
Theron, G.B.2
Schubert, P.T.3
-
9
-
-
0033680577
-
Placental abnormalities associated with human immunodeficiency virus type 1 infection and perinatal transmission in Bangkok, Thailand
-
Schwartz DA, Sungkarat S, Shaffer N, et al. Placental abnormalities associated with human immunodeficiency virus type 1 infection and perinatal transmission in Bangkok, Thailand. J Infect Dis. 2000;182:1652-1657.
-
(2000)
J Infect Dis.
, vol.182
, pp. 1652-1657
-
-
Schwartz, D.A.1
Sungkarat, S.2
Shaffer, N.3
-
10
-
-
40549139520
-
Maternal HIV status and pregnancy outcomes in northeastern Tanzania: A registry-based study
-
Habib NA, Daltveit AK, Bergsjø P, et al. Maternal HIV status and pregnancy outcomes in northeastern Tanzania: a registry-based study. BJOG. 2008;115:616-624.
-
(2008)
BJOG
, vol.115
, pp. 616-624
-
-
Habib, N.A.1
Daltveit, A.K.2
Bergsjø, P.3
-
11
-
-
84861537697
-
Maternal HIV infection associated with small-for-gestational age infants but not preterm births: Evidence from rural South Africa
-
Ndirangu J, Newell ML, Bland RM, et al. Maternal HIV infection associated with small-for-gestational age infants but not preterm births: evidence from rural South Africa. Hum Reprod. 2012;27:1846-1856.
-
(2012)
Hum Reprod.
, vol.27
, pp. 1846-1856
-
-
Ndirangu, J.1
Newell, M.L.2
Bland, R.M.3
-
12
-
-
0028972960
-
The effect of human immunodeficiency virus infection on birthweight, and infant and child mortality in urban Malawi
-
Taha TE, Dallabetta GA, Canner JK, et al. The effect of human immunodeficiency virus infection on birthweight, and infant and child mortality in urban Malawi. Int J Epidemiol. 1995;24:1022-1029.
-
(1995)
Int J Epidemiol.
, vol.24
, pp. 1022-1029
-
-
Taha, T.E.1
Dallabetta, G.A.2
Canner, J.K.3
-
13
-
-
70349263446
-
Anthropometric indices of infants born to HIV-1-infected mothers: A prospective cohort study in Lagos, Nigeria
-
Ezeaka VC, Iroha EO, Akinsulie AO, et al. Anthropometric indices of infants born to HIV-1-infected mothers: a prospective cohort study in Lagos, Nigeria. Int J STD AIDS. 2009;20:545-548.
-
(2009)
Int J STD AIDS.
, vol.20
, pp. 545-548
-
-
Ezeaka, V.C.1
Iroha, E.O.2
Akinsulie, A.O.3
-
14
-
-
0025763743
-
Perinatal transmission of HIV-1: Lack of impact of maternal HIV infection on characteristics of livebirths and on neonatal mortality in Kigali, Rwanda
-
Lepage P, Dabis F, Hitimana DG, et al. Perinatal transmission of HIV-1: lack of impact of maternal HIV infection on characteristics of livebirths and on neonatal mortality in Kigali, Rwanda. AIDS. 1991;5:295-300.
-
(1991)
AIDS
, vol.5
, pp. 295-300
-
-
Lepage, P.1
Dabis, F.2
Hitimana, D.G.3
-
15
-
-
7344221468
-
Safety of the maternal-infant zidovudine regimen utilized in the Pediatric AIDS Clinical Trial Group 076 Study
-
Sperling RS, Shapiro DE, McSherry GD, et al. Safety of the maternal-infant zidovudine regimen utilized in the Pediatric AIDS Clinical Trial Group 076 Study. AIDS. 1998;12:1805-1813.
-
(1998)
AIDS
, vol.12
, pp. 1805-1813
-
-
Sperling, R.S.1
Shapiro, D.E.2
McSherry, G.D.3
-
16
-
-
0033528521
-
6-month efficacy, tolerance, and acceptability of a short regimen of oral zidovudine to reduce vertical transmission of HIV in breastfed children in Côte d'Ivoire and Burkina Faso: A double-blind placebo-controlled multicentre trial
-
DITRAME Study Group. DIminution de la Transmission Mère-Enfant
-
Dabis F, Msellati P, Meda N, et al. 6-month efficacy, tolerance, and acceptability of a short regimen of oral zidovudine to reduce vertical transmission of HIV in breastfed children in Côte d'Ivoire and Burkina Faso: a double-blind placebo-controlled multicentre trial. DITRAME Study Group. DIminution de la Transmission Mère-Enfant. Lancet. 1999;353:786-792.
-
(1999)
Lancet.
, vol.353
, pp. 786-792
-
-
Dabis, F.1
Msellati, P.2
Meda, N.3
-
17
-
-
0035227158
-
Safety of late in utero exposure to zidovudine in infants born to human immunodeficiency virus-infected mothers: Bangkok
-
Bangkok Collaborative Perinatal HIV Transmission Study Group
-
Chotpitayasunondh T, Vanprapar N, Simonds RJ, et al. Safety of late in utero exposure to zidovudine in infants born to human immunodeficiency virus-infected mothers: Bangkok. Bangkok Collaborative Perinatal HIV Transmission Study Group. Pediatrics. 2001;107:E5.
-
(2001)
Pediatrics.
, vol.107
-
-
Chotpitayasunondh, T.1
Vanprapar, N.2
Simonds, R.J.3
-
18
-
-
33645550495
-
Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmission
-
Briand N, Le Coeur S, Traisathit P, et al. Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmission. Pediatr Infect Dis J. 2006;25:325-332.
-
(2006)
Pediatr Infect Dis J.
, vol.25
, pp. 325-332
-
-
Briand, N.1
Le Coeur, S.2
Traisathit, P.3
-
19
-
-
0032991193
-
Is zidovudine therapy in pregnant HIV- infected women associated with gestational age and birthweight?
-
The European Collaborative Study
-
The European Collaborative Study. Is zidovudine therapy in pregnant HIV- infected women associated with gestational age and birthweight? AIDS. 1999;13:119-124.
-
(1999)
AIDS
, vol.13
, pp. 119-124
-
-
-
20
-
-
0036174438
-
Assessment of mitochondrial toxicity in human cells treated with tenofovir: Comparison with other nucleoside reverse transcriptase inhibitors
-
Birkus G, Hitchcock MJ, Cihlar T. Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors. Antimicrob Agents Chemother. 2002;46:716-723.
-
(2002)
Antimicrob Agents Chemother.
, vol.46
, pp. 716-723
-
-
Birkus, G.1
Hitchcock, M.J.2
Cihlar, T.3
-
21
-
-
1642420304
-
Relationship between antiviral activity and host toxicity: Comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine- triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase
-
Feng JY, Murakami E, Zorca SM, et al. Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase. Antimicrob Agents Chemother. 2004;48:1300-1306.
-
(2004)
Antimicrob Agents Chemother.
, vol.48
, pp. 1300-1306
-
-
Feng, J.Y.1
Murakami, E.2
Zorca, S.M.3
-
23
-
-
48749127377
-
Towards universal access: Scaling up priority HIV/AIDS interventions in the health sector
-
Available at Accessed May 10, 2013
-
WHO. Towards universal access: scaling up priority HIV/AIDS interventions in the health sector. Progress report 2009. Available at: http://www. unaidsrstesa.org/resources/reports/towards-universal-access-scaling-priority- hivaids-interventions-health-sector. Accessed May 10, 2013.
-
WHO Progress Report 2009
-
-
-
24
-
-
84858139266
-
Global HIV/AIDS response: Epidemic update and health sector progress towards universal access
-
WHO Available at Accessed May 10, 2012
-
WHO. Global HIV/AIDS response: epidemic update and health sector progress towards universal access. Progress report 2011. Available at: http://www.who.int/hiv/pub/progress-report2011/en/. Accessed May 10, 2012.
-
Progress Report 2011
-
-
-
25
-
-
84861526377
-
Safety of tenofovir use during pregnancy: Early growth outcomes in HIV-exposed uninfected infants
-
Pediatric HIV/AIDS Cohort Study (PHACS)
-
Siberry GK, Williams PL, Mendez H, et al.; Pediatric HIV/AIDS Cohort Study (PHACS). Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants. AIDS. 2012;26:1151-1159.
-
(2012)
AIDS
, vol.26
, pp. 1151-1159
-
-
Siberry, G.K.1
Williams, P.L.2
Mendez, H.3
-
26
-
-
84891915489
-
Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy
-
P1025 Team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group
-
Ransom CE, Huo Y, Patel K, et al.; P1025 Team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group. Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy. J Acquir Immune Defic Syndr. 2013;64:374-381.
-
(2013)
J Acquir Immune Defic Syndr.
, vol.64
, pp. 374-381
-
-
Ransom, C.E.1
Huo, Y.2
Patel, K.3
-
27
-
-
84861553641
-
Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial
-
DART trial team
-
Gibb DM, Kizito H, Russell EC, et al.; DART trial team. Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial. PLoS Med. 2012;9:e1001217.
-
(2012)
PLoS Med.
, vol.9
-
-
Gibb, D.M.1
Kizito, H.2
Russell, E.C.3
-
28
-
-
0037071791
-
Antiretroviral therapy during pregnancy and the risk of an adverse outcome
-
Tuomala RE, Shapiro DE, Mofenson LM, et al. Antiretroviral therapy during pregnancy and the risk of an adverse outcome. N Engl J Med. 2002;346:1863-1870.
-
(2002)
N Engl J Med.
, vol.346
, pp. 1863-1870
-
-
Tuomala, R.E.1
Shapiro, D.E.2
Mofenson, L.M.3
-
29
-
-
0037379462
-
Exposure to antiretroviral therapy in utero or early life: The health of uninfected children born to HIV-infected women
-
European Collaborative Study
-
European Collaborative Study. Exposure to antiretroviral therapy in utero or early life: the health of uninfected children born to HIV-infected women. J Acquir Immune Defic Syndr. 2003;32:380-387.
-
(2003)
J Acquir Immune Defic Syndr.
, vol.32
, pp. 380-387
-
-
-
30
-
-
84869066654
-
Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana
-
Chen JY, Ribaudo HJ, Souda S, et al. Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana. J Infect Dis. 2012;206:1695-1705.
-
(2012)
J Infect Dis.
, vol.206
, pp. 1695-1705
-
-
Chen, J.Y.1
Ribaudo, H.J.2
Souda, S.3
-
31
-
-
59849097134
-
Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire
-
Ekouevi DK, Coffie PA, Becquet R, et al. Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire. AIDS. 2008;22:1815-1820.
-
(2008)
AIDS
, vol.22
, pp. 1815-1820
-
-
Ekouevi, D.K.1
Coffie, P.A.2
Becquet, R.3
-
32
-
-
84877113825
-
Combination antiretroviral use and preterm birth
-
Pediatric HIV/AIDS Cohort Study
-
Watts DH, Williams PL, Kacanek D, et al.; Pediatric HIV/AIDS Cohort Study. Combination antiretroviral use and preterm birth. J Infect Dis. 2013;207:612-621.
-
(2013)
J Infect Dis.
, vol.207
, pp. 612-621
-
-
Watts, D.H.1
Williams, P.L.2
Kacanek, D.3
-
33
-
-
84861918643
-
Infant outcomes after maternal antiretroviral exposure in resource-limited settings
-
ACTG 5190/PACTG 1054 Study Team
-
Nielsen-Saines K, Komarow L, Cu-Uvin S, et al.; ACTG 5190/PACTG 1054 Study Team. Infant outcomes after maternal antiretroviral exposure in resource-limited settings. Pediatrics. 2012;129:e1525-e1532.
-
(2012)
Pediatrics.
, vol.129
-
-
Nielsen-Saines, K.1
Komarow, L.2
Cu-Uvin, S.3
-
34
-
-
84863696899
-
Small-for-gestational-age births in pregnant women with HIV, due to severity of HIV disease, not antiretroviral therapy
-
Aaron E, Bonacquisti A, Mathew L, et al. Small-for-gestational-age births in pregnant women with HIV, due to severity of HIV disease, not antiretroviral therapy. Infect Dis Obstet Gynecol. 2012;2012:135030.
-
(2012)
Infect Dis Obstet Gynecol.
, vol.2012
, pp. 135030
-
-
Aaron, E.1
Bonacquisti, A.2
Mathew, L.3
-
35
-
-
0028820778
-
Maternal HIV infection, drug use, and growth of uninfected children in their first 3 years
-
Ross A, Raab GM, Mok J, et al. Maternal HIV infection, drug use, and growth of uninfected children in their first 3 years. Arch Dis Child. 1995;73:490-495.
-
(1995)
Arch Dis Child.
, vol.73
, pp. 490-495
-
-
Ross, A.1
Raab, G.M.2
Mok, J.3
-
36
-
-
17144457068
-
Height, weight, and growth in children born to mothers with HIV-1 infection in Europe
-
European Collaborative Study
-
Newell ML, Borja MC, Peckham C; European Collaborative Study. Height, weight, and growth in children born to mothers with HIV-1 infection in Europe. Pediatrics. 2003;111:e52-e60.
-
(2003)
Pediatrics.
, vol.111
-
-
Newell, M.L.1
Borja, M.C.2
Peckham, C.3
-
37
-
-
0033550472
-
Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Pediatric AIDS Clinical Trials Group Protocol 219/076 Teams
-
Culnane M, Fowler M, Lee SS, et al. Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Pediatric AIDS Clinical Trials Group Protocol 219/076 Teams. JAMA. 1999;281:151-157.
-
(1999)
JAMA
, vol.281
, pp. 151-157
-
-
Culnane, M.1
Fowler, M.2
Lee, S.S.3
-
38
-
-
27444441657
-
Does exposure to antiretroviral therapy affect growth in the first 18 months of life in uninfected children born to HIV-infected women?
-
European Collaborative Study
-
Hankin C, Thorne C, Newell ML; European Collaborative Study. Does exposure to antiretroviral therapy affect growth in the first 18 months of life in uninfected children born to HIV-infected women? J Acquir Immune Defic Syndr. 2005;40:364-370.
-
(2005)
J Acquir Immune Defic Syndr
, vol.40
, pp. 364-370
-
-
Hankin, C.1
Thorne, C.2
Newell, M.L.3
-
39
-
-
70349622497
-
Growth of uninfected infants exposed to antiretrovirals born to HIV-infected woman
-
Ibieta MF, Cano JM, Amador JT, et al. [Growth of uninfected infants exposed to antiretrovirals born to HIV-infected woman]. An Pediatr (Barc). 2009;71:299-309.
-
(2009)
An Pediatr (Barc).
, vol.71
, pp. 299-309
-
-
Ibieta, M.F.1
Cano, J.M.2
Amador, J.T.3
-
40
-
-
84879417137
-
Growth and body composition of uninfected children exposed to human immunodeficiency virus: Comparison with a contemporary cohort and United States National Standards
-
e1
-
Neri D, Somarriba GA, Schaefer NN, et al. Growth and body composition of uninfected children exposed to human immunodeficiency virus: comparison with a contemporary cohort and United States National Standards. J Pediatr. 2013;163:249-54.e1.
-
(2013)
J Pediatr.
, vol.163
, pp. 249-254
-
-
Neri, D.1
Somarriba, G.A.2
Schaefer, N.N.3
-
41
-
-
78751618054
-
Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana
-
Powis KM, Smeaton L, Ogwu A, et al. Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana. J Acquir Immune Defic Syndr. 2011;56:131-138.
-
(2011)
J Acquir Immune Defic Syndr.
, vol.56
, pp. 131-138
-
-
Powis, K.M.1
Smeaton, L.2
Ogwu, A.3
-
43
-
-
0036232565
-
Bone mineral content is lower in prepubertal HIV-infected children
-
Arpadi SM, Horlick M, Thornton J, et al. Bone mineral content is lower in prepubertal HIV-infected children. J Acquir Immune Defic Syndr. 2002;29:450-454.
-
(2002)
J Acquir Immune Defic Syndr.
, vol.29
, pp. 450-454
-
-
Arpadi, S.M.1
Horlick, M.2
Thornton, J.3
-
44
-
-
0035964662
-
Bone mineral loss through increased bone turnover in HIV-infected children treated with highly active antiretroviral therapy
-
Mora S, Sala N, Bricalli D, et al. Bone mineral loss through increased bone turnover in HIV-infected children treated with highly active antiretroviral therapy. AIDS. 2001;15:1823-1829.
-
(2001)
AIDS
, vol.15
, pp. 1823-1829
-
-
Mora, S.1
Sala, N.2
Bricalli, D.3
-
45
-
-
0842313032
-
Longitudinal changes of bone mineral density and metabolism in antiretroviral-treated human immunodeficiency virus-infected children
-
Mora S, Zamproni I, Beccio S, et al. Longitudinal changes of bone mineral density and metabolism in antiretroviral-treated human immunodeficiency virus-infected children. J Clin Endocrinol Metab. 2004;89:24-28.
-
(2004)
J Clin Endocrinol Metab.
, vol.89
, pp. 24-28
-
-
Mora, S.1
Zamproni, I.2
Beccio, S.3
-
46
-
-
3042848853
-
Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral- naive patients: A 3-year randomized trial
-
903 Study Group
-
Gallant JE, Staszewski S, Pozniak AL, et al.; 903 Study Group. Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral- naive patients: a 3-year randomized trial. JAMA. 2004;292:191-201.
-
(2004)
JAMA
, vol.292
, pp. 191-201
-
-
Gallant, J.E.1
Staszewski, S.2
Pozniak, A.L.3
-
47
-
-
44649084952
-
Risk factors for decreased bone density and effects of HIV on bone in the elderly
-
Jones S, Restrepo D, Kasowitz A, et al. Risk factors for decreased bone density and effects of HIV on bone in the elderly. Osteoporos Int. 2008;19:913-918.
-
(2008)
Osteoporos Int.
, vol.19
, pp. 913-918
-
-
Jones, S.1
Restrepo, D.2
Kasowitz, A.3
-
48
-
-
33749059820
-
Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy: Impact on bone mineral density in HIV-infected children
-
Gafni RI, Hazra R, Reynolds JC, et al. Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy: impact on bone mineral density in HIV-infected children. Pediatrics. 2006;118:e711-e718.
-
(2006)
Pediatrics.
, vol.118
-
-
Gafni, R.I.1
Hazra, R.2
Reynolds, J.C.3
-
49
-
-
40749108414
-
Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus
-
Purdy JB, Gafni RI, Reynolds JC, et al. Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus. J Pediatr. 2008;152:582-584.
-
(2008)
J Pediatr.
, vol.152
, pp. 582-584
-
-
Purdy, J.B.1
Gafni, R.I.2
Reynolds, J.C.3
-
50
-
-
27944475515
-
A 12-month treatment with tenofovir does not impair bone mineral accrual in HIV-infected children
-
Giacomet V, Mora S, Martelli L, et al. A 12-month treatment with tenofovir does not impair bone mineral accrual in HIV-infected children. J Acquir Immune Defic Syndr. 2005;40:448-450.
-
(2005)
J Acquir Immune Defic Syndr.
, vol.40
, pp. 448-450
-
-
Giacomet, V.1
Mora, S.2
Martelli, L.3
-
51
-
-
0033040847
-
Administration of 9-[ 2-®-(phosphonomethoxy)propyl]adenine (PMPA) to gravid and infant rhesus macaques (Macaca mulatta): Safety and efficacy studies
-
Tarantal AF, Marthas ML, Shaw JP, et al. Administration of 9-[ 2-®-(phosphonomethoxy)propyl]adenine (PMPA) to gravid and infant rhesus macaques (Macaca mulatta): safety and efficacy studies. J Acquir Immune Defic Syndr Hum Retrovirol. 1999;20:323-333.
-
(1999)
J Acquir Immune Defic Syndr Hum Retrovirol.
, vol.20
, pp. 323-333
-
-
Tarantal, A.F.1
Marthas, M.L.2
Shaw, J.P.3
-
52
-
-
0036500034
-
Fetal and maternal outcome after administration of tenofovir to gravid rhesus monkeys (Macaca mulatta)
-
Tarantal AF, Castillo A, Ekert JE, et al. Fetal and maternal outcome after administration of tenofovir to gravid rhesus monkeys (Macaca mulatta). J Acquir Immune Defic Syndr. 2002;29:207-220.
-
(2002)
J Acquir Immune Defic Syndr.
, vol.29
, pp. 207-220
-
-
Tarantal, A.F.1
Castillo, A.2
Ekert, J.E.3
-
53
-
-
81255178826
-
Exposure to antiretroviral agents during pregnancy does not alter bone status in infants
-
Mora S, Giacomet V, Viganò A, et al. Exposure to antiretroviral agents during pregnancy does not alter bone status in infants. Bone. 2012;50:255-258.
-
(2012)
Bone.
, vol.50
, pp. 255-258
-
-
Mora, S.1
Giacomet, V.2
Viganò, A.3
-
54
-
-
83455179365
-
In utero exposure to tenofovir disoproxil fumarate does not impair growth and bone health in HIV-uninfected children born to HIV-infected mothers
-
Viganò A, Mora S, Giacomet V, et al. In utero exposure to tenofovir disoproxil fumarate does not impair growth and bone health in HIV-uninfected children born to HIV-infected mothers. Antivir Ther. 2011;16:1259-1266.
-
(2011)
Antivir Ther.
, vol.16
, pp. 1259-1266
-
-
Viganò, A.1
Mora, S.2
Giacomet, V.3
-
55
-
-
84902538629
-
-
Study of effects of tenofovir on bone health and kidneys during pregnancy and breastfeeding. Available at Accessed June 5, 2013
-
Study of effects of tenofovir on bone health and kidneys during pregnancy and breastfeeding. Available at: http://clinicaltrials.gov/ct2/show/NCT0106 6858?term=impaact+1077&rank=1. Accessed June 5, 2013.
-
-
-
-
56
-
-
0033604060
-
Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues
-
Blanche S, Tardieu M, Rustin P, et al. Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues. Lancet. 1999;354:1084-1089.
-
(1999)
Lancet.
, vol.354
, pp. 1084-1089
-
-
Blanche, S.1
Tardieu, M.2
Rustin, P.3
-
57
-
-
0024406638
-
Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma
-
König H, Behr E, Löwer J, et al. Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma. Antimicrob Agents Chemother. 1989;33:2109-2114.
-
(1989)
Antimicrob Agents Chemother.
, vol.33
, pp. 2109-2114
-
-
König, H.1
Behr, E.2
Löwer, J.3
-
58
-
-
0025274663
-
Mitochondrial myopathy caused by long-term zidovudine therapy
-
Dalakas MC, Illa I, Pezeshkpour GH, et al. Mitochondrial myopathy caused by long-term zidovudine therapy. N Engl J Med. 1990;322:1098-1105.
-
(1990)
N Engl J Med.
, vol.322
, pp. 1098-1105
-
-
Dalakas, M.C.1
Illa, I.2
Pezeshkpour, G.H.3
-
59
-
-
0028158398
-
Cardiac mitochondrial DNA polymerase- gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine
-
Lewis W, Simpson JF, Meyer RR. Cardiac mitochondrial DNA polymerase- gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine. Circ Res. 1994;74:344-348.
-
(1994)
Circ Res.
, vol.74
, pp. 344-348
-
-
Lewis, W.1
Simpson, J.F.2
Meyer, R.R.3
-
60
-
-
0026786397
-
Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA
-
Copeland WC, Chen MS, Wang TS. Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. J Biol Chem. 1992;267:21459-21464.
-
(1992)
J Biol Chem.
, vol.267
, pp. 21459-21464
-
-
Copeland, W.C.1
Chen, M.S.2
Wang, T.S.3
-
61
-
-
0014545828
-
The enzymatic termination of polydeoxynucleotides by 2',3'- dideoxyadenosine triphosphate
-
Toji L, Cohen SS. The enzymatic termination of polydeoxynucleotides by 2',3'-dideoxyadenosine triphosphate. Proc Natl Acad Sci USA. 1969;63:871-877.
-
(1969)
Proc Natl Acad Sci USA.
, vol.63
, pp. 871-877
-
-
Toji, L.1
Cohen, S.S.2
-
62
-
-
0029077056
-
Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase
-
Eriksson S, Xu B, Clayton DA. Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase. J Biol Chem. 1995;270:18929-18934.
-
(1995)
J Biol Chem.
, vol.270
, pp. 18929-18934
-
-
Eriksson, S.1
Xu, B.2
Clayton, D.A.3
-
63
-
-
0034192228
-
Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine
-
Gerschenson M, Erhart SW, Paik CY, et al. Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine. AIDS Res Hum Retroviruses. 2000;16:635-644.
-
(2000)
AIDS Res Hum Retroviruses.
, vol.16
, pp. 635-644
-
-
Gerschenson, M.1
Erhart, S.W.2
Paik, C.Y.3
-
64
-
-
0034209854
-
Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria
-
Ewings EL, Gerschenson M, St Claire MC, et al. Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria. J Acquir Immune Defic Syndr. 2000;24:100-105.
-
(2000)
J Acquir Immune Defic Syndr.
, vol.24
, pp. 100-105
-
-
Ewings, E.L.1
Gerschenson, M.2
St Claire, M.C.3
-
65
-
-
27144536621
-
Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors
-
Divi RL, Leonard SL, Kuo MM, et al. Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors. Cardiovasc Toxicol. 2005;5:333-346.
-
(2005)
Cardiovasc Toxicol.
, vol.5
, pp. 333-346
-
-
Divi, R.L.1
Leonard, S.L.2
Kuo, M.M.3
-
66
-
-
84876906224
-
Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age
-
Olivero OA, Torres LR, Gorjifard S, et al. Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age. J Infect Dis. 2013;208:244-248.
-
(2013)
J Infect Dis.
, vol.208
, pp. 244-248
-
-
Olivero, O.A.1
Torres, L.R.2
Gorjifard, S.3
-
67
-
-
58549094952
-
Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1
-
Torres SM, Walker DM, McCash CL, et al. Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1. Environ Mol Mutagen. 2009;50:10-26.
-
(2009)
Environ Mol Mutagen.
, vol.50
, pp. 10-26
-
-
Torres, S.M.1
Walker, D.M.2
McCash, C.L.3
-
68
-
-
84876926913
-
Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination
-
André-Schmutz I, Dal-Cortivo L, Six E, et al. Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination. J Infect Dis. 2013;208:235-243.
-
(2013)
J Infect Dis.
, vol.208
, pp. 235-243
-
-
André-Schmutz, I.1
Dal-Cortivo, L.2
Six, E.3
-
69
-
-
0038078685
-
Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers
-
Women and Infants Transmission Study (WITS) Group
-
Poirier MC, Divi RL, Al-Harthi L, et al.; Women and Infants Transmission Study (WITS) Group. Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers. J Acquir Immune Defic Syndr. 2003;33:175-183.
-
(2003)
J Acquir Immune Defic Syndr.
, vol.33
, pp. 175-183
-
-
Poirier, M.C.1
Divi, R.L.2
Al-Harthi, L.3
-
70
-
-
2342613668
-
Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir
-
Divi RL, Walker VE, Wade NA, et al. Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir. AIDS. 2004;18:1013-1021.
-
(2004)
AIDS
, vol.18
, pp. 1013-1021
-
-
Divi, R.L.1
Walker, V.E.2
Wade, N.A.3
-
71
-
-
0037378552
-
Placenta and cord blood mitochondrial DNA toxicity in HIV-infected women receiving nucleoside reverse transcriptase inhibitors during pregnancy
-
Shiramizu B, Shikuma KM, Kamemoto L, et al. Placenta and cord blood mitochondrial DNA toxicity in HIV-infected women receiving nucleoside reverse transcriptase inhibitors during pregnancy. J Acquir Immune Defic Syndr. 2003;32:370-374.
-
(2003)
J Acquir Immune Defic Syndr.
, vol.32
, pp. 370-374
-
-
Shiramizu, B.1
Shikuma, K.M.2
Kamemoto, L.3
-
72
-
-
71949085037
-
Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women
-
Aldrovandi GM, Chu C, Shearer WT, et al. Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women. Pediatrics. 2009;124:e1189-e1197.
-
(2009)
Pediatrics.
, vol.124
-
-
Aldrovandi, G.M.1
Chu, C.2
Shearer, W.T.3
-
73
-
-
51749113366
-
Perinatal exposure to antiretroviral therapy is associated with increased blood mitochondrial DNA levels and decreased mitochondrial gene expression in infants
-
Côté HC, Raboud J, Bitnun A, et al. Perinatal exposure to antiretroviral therapy is associated with increased blood mitochondrial DNA levels and decreased mitochondrial gene expression in infants. J Infect Dis. 2008;198:851-859.
-
(2008)
J Infect Dis.
, vol.198
, pp. 851-859
-
-
Côté, H.C.1
Raboud, J.2
Bitnun, A.3
-
74
-
-
44949129640
-
Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy
-
AIDS Clinical Trials Group A5084
-
McComsey GA, Kang M, Ross AC, et al.; AIDS Clinical Trials Group A5084. Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy. HIV Clin Trials. 2008;9:126-136.
-
(2008)
HIV Clin Trials.
, vol.9
, pp. 126-136
-
-
McComsey, G.A.1
Kang, M.2
Ross, A.C.3
-
75
-
-
84864584463
-
Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords
-
Kunz A, von Wurmb-Schwark N, Sewangi J, et al. Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords. PLoS One. 2012;7:e41637.
-
(2012)
PLoS One.
, vol.7
-
-
Kunz, A.1
Von Wurmb-Schwark, N.2
Sewangi, J.3
-
76
-
-
84855353782
-
Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress
-
Ross AC, Leong T, Avery A, et al. Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress. HIV Med. 2012;13:98-106.
-
(2012)
HIV Med.
, vol.13
, pp. 98-106
-
-
Ross, A.C.1
Leong, T.2
Avery, A.3
-
77
-
-
33748103186
-
Mitochondrial (mt) DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients
-
Maagaard A, Holberg-Petersen M, Kollberg G, et al. Mitochondrial (mt) DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients. Antivir Ther. 2006;11:601-608.
-
(2006)
Antivir Ther.
, vol.11
, pp. 601-608
-
-
Maagaard, A.1
Holberg-Petersen, M.2
Kollberg, G.3
-
78
-
-
67649194801
-
Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy
-
Gingelmaier A, Grubert TA, Kost BP, et al. Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy. Antivir Ther. 2009;14:331-338.
-
(2009)
Antivir Ther.
, vol.14
, pp. 331-338
-
-
Gingelmaier, A.1
Grubert, T.A.2
Kost, B.P.3
-
79
-
-
84873059408
-
Abnormal newborn screens and acylcarnitines in HIV-exposed and ARV-exposed infants
-
Kirmse B, Hobbs CV, Peter I, et al. Abnormal newborn screens and acylcarnitines in HIV-exposed and ARV-exposed infants. Pediatr Infect Dis J. 2013;32:146-150.
-
(2013)
Pediatr Infect Dis J.
, vol.32
, pp. 146-150
-
-
Kirmse, B.1
Hobbs, C.V.2
Peter, I.3
-
80
-
-
0033604038
-
Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
-
Brinkman K, Smeitink JA, Romijn JA, et al. Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy. Lancet. 1999;354:1112-1115.
-
(1999)
Lancet.
, vol.354
, pp. 1112-1115
-
-
Brinkman, K.1
Smeitink, J.A.2
Romijn, J.A.3
-
81
-
-
70849087607
-
Lactic acidosis in HIV-exposed infants with perinatal exposure to antiretroviral therapy
-
Shah I. Lactic acidosis in HIV-exposed infants with perinatal exposure to antiretroviral therapy. Ann Trop Paediatr. 2009;29:257-261.
-
(2009)
Ann Trop Paediatr.
, vol.29
, pp. 257-261
-
-
Shah, I.1
-
82
-
-
16644382547
-
Hyperlactatemia in human immunodeficiency virus-uninfected infants who are exposed to antiretrovirals
-
Noguera A, Fortuny C, Muñoz-Almagro C, et al. Hyperlactatemia in human immunodeficiency virus-uninfected infants who are exposed to antiretrovirals. Pediatrics. 2004;114:e598-e603.
-
(2004)
Pediatrics.
, vol.114
-
-
Noguera, A.1
Fortuny, C.2
Muñoz-Almagro, C.3
-
83
-
-
33750138097
-
Serum lactate levels in infants exposed peripartum to antiretroviral agents to prevent mother- to-child transmission of HIV: Agence Nationale de Recherches sur le SIDA et les Hépatites Virales 1209 study, Abidjan, Ivory Coast
-
Agence Nationale de Recherches Sur le SIDA 1201/1202 Ditrame Plus Study Group
-
Ekouevi DK, Touré R, Becquet R, et al.; Agence Nationale de Recherches Sur le SIDA 1201/1202 Ditrame Plus Study Group. Serum lactate levels in infants exposed peripartum to antiretroviral agents to prevent mother- to-child transmission of HIV: Agence Nationale de Recherches Sur le SIDA et les Hépatites Virales 1209 study, Abidjan, Ivory Coast. Pediatrics. 2006;118:e1071-e1077.
-
(2006)
Pediatrics.
, vol.118
-
-
Ekouevi, D.K.1
Touré, R.2
Becquet, R.3
-
84
-
-
81855164872
-
Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications
-
Pediatric HIVAIDS Cohort Study
-
Crain MJ, Williams PL, Griner R, et al.; Pediatric HIVAIDS Cohort Study. Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications. Pediatr Infect Dis J. 2011;30:1069-1074.
-
(2011)
Pediatr Infect Dis J.
, vol.30
, pp. 1069-1074
-
-
Crain, M.J.1
Williams, P.L.2
Griner, R.3
-
85
-
-
0042232027
-
Persistent mitochondrial dysfunction in HIV-1-exposed but uninfected infants: Clinical screening in a large prospective cohort
-
French Perinatal Cohort Study Group
-
Barret B, Tardieu M, Rustin P, et al.; French Perinatal Cohort Study Group. Persistent mitochondrial dysfunction in HIV-1-exposed but uninfected infants: clinical screening in a large prospective cohort. AIDS. 2003;17:1769-1785.
-
(2003)
AIDS
, vol.17
, pp. 1769-1785
-
-
Barret, B.1
Tardieu, M.2
Rustin, P.3
-
86
-
-
0034319154
-
Nucleoside exposure in the children of HIV-infected women receiving antiretroviral drugs: Absence of clear evidence for mitochondrial disease in children who died before 5 years of age in five United States cohorts
-
The Perinatal Safety Review Working Group
-
The Perinatal Safety Review Working Group. Nucleoside exposure in the children of HIV-infected women receiving antiretroviral drugs: absence of clear evidence for mitochondrial disease in children who died before 5 years of age in five United States cohorts. J Acquir Immune Defic Syndr. 2000;25:261-268.
-
(2000)
J Acquir Immune Defic Syndr.
, vol.25
, pp. 261-268
-
-
-
87
-
-
0033637597
-
Drug safety during pregnancy and in infants. Lack of mortality related to mitochondrial dysfunction among perinatally HIV-exposed children in pediatric HIV surveillance
-
Perinatal Safety Review Working Group; State and Local Health Department HIV/AIDS Surveillance Programs
-
Lindegren ML, Rhodes P, Gordon L, et al.; Perinatal Safety Review Working Group; State and Local Health Department HIV/AIDS Surveillance Programs. Drug safety during pregnancy and in infants. Lack of mortality related to mitochondrial dysfunction among perinatally HIV-exposed children in pediatric HIV surveillance. Ann N Y Acad Sci. 2000;918:222-235.
-
(2000)
Ann N y Acad Sci.
, vol.918
, pp. 222-235
-
-
Lindegren, M.L.1
Rhodes, P.2
Gordon, L.3
-
88
-
-
74049132363
-
Potential confounding of the association between exposure to nucleoside analogues and mitochondrial dysfunction in HIV-uninfected and indeterminate infants
-
Brogly SB, Foca M, Deville JG, et al. Potential confounding of the association between exposure to nucleoside analogues and mitochondrial dysfunction in HIV-uninfected and indeterminate infants. J Acquir Immune Defic Syndr. 2010;53:154-157.
-
(2010)
J Acquir Immune Defic Syndr.
, vol.53
, pp. 154-157
-
-
Brogly, S.B.1
Foca, M.2
Deville, J.G.3
-
89
-
-
0034648743
-
Absence of cardiac toxicity of zidovudine in infants
-
Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group
-
Lipshultz SE, Easley KA, Orav EJ, et al. Absence of cardiac toxicity of zidovudine in infants. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group. N Engl J Med. 2000;343:759-766.
-
(2000)
N Engl J Med.
, vol.343
, pp. 759-766
-
-
Lipshultz, S.E.1
Easley, K.A.2
Orav, E.J.3
-
90
-
-
34247609876
-
In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children
-
Brogly SB, Ylitalo N, Mofenson LM, et al. In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children. AIDS. 2007;21:929-938. Development
-
(2007)
AIDS
, vol.21
, pp. 929-938
-
-
Brogly, S.B.1
Ylitalo, N.2
Mofenson, L.M.3
|