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Volumn 33, Issue 7, 2014, Pages 734-740

Metabolic complications of in utero maternal HIV and antiretroviral exposure in HIV-exposed infants

Author keywords

ARV; complications; exposure; HIV; metabolic

Indexed keywords

ANTIRETROVIRUS AGENT; DIDANOSINE; EFAVIRENZ; EMTRICITABINE PLUS TENOFOVIR DISOPROXIL; LAMIVUDINE PLUS ZIDOVUDINE; MITOCHONDRIAL DNA; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; TENOFOVIR; TENOFOVIR DISOPROXIL; ZIDOVUDINE;

EID: 84902543309     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0000000000000224     Document Type: Article
Times cited : (39)

References (90)
  • 2
    • 40149093414 scopus 로고    scopus 로고
    • Antiretroviral treatment in pregnancy
    • Stek AM. Antiretroviral treatment in pregnancy. Curr Opin HIV AIDS. 2008;3:155-160.
    • (2008) Curr Opin HIV AIDS. , vol.3 , pp. 155-160
    • Stek, A.M.1
  • 3
    • 20944443338 scopus 로고    scopus 로고
    • The safety of antiretroviral drugs in pregnancy
    • Thorne C, Newell ML. The safety of antiretroviral drugs in pregnancy. Expert Opin Drug Saf. 2005;4:323-335.
    • (2005) Expert Opin Drug Saf. , vol.4 , pp. 323-335
    • Thorne, C.1    Newell, M.L.2
  • 4
    • 4644291083 scopus 로고    scopus 로고
    • Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy
    • Watts DH, Covington DL, Beckerman K, et al. Assessing the risk of birth defects associated with antiretroviral exposure during pregnancy. Am J Obstet Gynecol. 2004;191:985-992.
    • (2004) Am J Obstet Gynecol. , vol.191 , pp. 985-992
    • Watts, D.H.1    Covington, D.L.2    Beckerman, K.3
  • 5
    • 0024981025 scopus 로고
    • Rise and fall of Western diseases
    • Barker DJ. Rise and fall of Western diseases. Nature. 1989;338:371-372.
    • (1989) Nature. , vol.338 , pp. 371-372
    • Barker, D.J.1
  • 6
    • 0024469193 scopus 로고
    • Weight in infancy and death from ischaemic heart disease
    • Barker DJ, Winter PD, Osmond C, et al. Weight in infancy and death from ischaemic heart disease. Lancet. 1989;2:577-580.
    • (1989) Lancet. , vol.2 , pp. 577-580
    • Barker, D.J.1    Winter, P.D.2    Osmond, C.3
  • 7
    • 0024230485 scopus 로고
    • Morphological aspects of the placenta in HIV pregnancies
    • Jauniaux E, Nessmann C, Imbert MC, et al. Morphological aspects of the placenta in HIV pregnancies. Placenta. 1988;9:633-642.
    • (1988) Placenta. , vol.9 , pp. 633-642
    • Jauniaux, E.1    Nessmann, C.2    Imbert, M.C.3
  • 8
    • 84869118362 scopus 로고    scopus 로고
    • Morphologic changes in the placentas of HIV-positive women and their association with degree of immune suppression
    • Vermaak A, Theron GB, Schubert PT, et al. Morphologic changes in the placentas of HIV-positive women and their association with degree of immune suppression. Int J Gynaecol Obstet. 2012;119:239-243.
    • (2012) Int J Gynaecol Obstet. , vol.119 , pp. 239-243
    • Vermaak, A.1    Theron, G.B.2    Schubert, P.T.3
  • 9
    • 0033680577 scopus 로고    scopus 로고
    • Placental abnormalities associated with human immunodeficiency virus type 1 infection and perinatal transmission in Bangkok, Thailand
    • Schwartz DA, Sungkarat S, Shaffer N, et al. Placental abnormalities associated with human immunodeficiency virus type 1 infection and perinatal transmission in Bangkok, Thailand. J Infect Dis. 2000;182:1652-1657.
    • (2000) J Infect Dis. , vol.182 , pp. 1652-1657
    • Schwartz, D.A.1    Sungkarat, S.2    Shaffer, N.3
  • 10
    • 40549139520 scopus 로고    scopus 로고
    • Maternal HIV status and pregnancy outcomes in northeastern Tanzania: A registry-based study
    • Habib NA, Daltveit AK, Bergsjø P, et al. Maternal HIV status and pregnancy outcomes in northeastern Tanzania: a registry-based study. BJOG. 2008;115:616-624.
    • (2008) BJOG , vol.115 , pp. 616-624
    • Habib, N.A.1    Daltveit, A.K.2    Bergsjø, P.3
  • 11
    • 84861537697 scopus 로고    scopus 로고
    • Maternal HIV infection associated with small-for-gestational age infants but not preterm births: Evidence from rural South Africa
    • Ndirangu J, Newell ML, Bland RM, et al. Maternal HIV infection associated with small-for-gestational age infants but not preterm births: evidence from rural South Africa. Hum Reprod. 2012;27:1846-1856.
    • (2012) Hum Reprod. , vol.27 , pp. 1846-1856
    • Ndirangu, J.1    Newell, M.L.2    Bland, R.M.3
  • 12
    • 0028972960 scopus 로고
    • The effect of human immunodeficiency virus infection on birthweight, and infant and child mortality in urban Malawi
    • Taha TE, Dallabetta GA, Canner JK, et al. The effect of human immunodeficiency virus infection on birthweight, and infant and child mortality in urban Malawi. Int J Epidemiol. 1995;24:1022-1029.
    • (1995) Int J Epidemiol. , vol.24 , pp. 1022-1029
    • Taha, T.E.1    Dallabetta, G.A.2    Canner, J.K.3
  • 13
    • 70349263446 scopus 로고    scopus 로고
    • Anthropometric indices of infants born to HIV-1-infected mothers: A prospective cohort study in Lagos, Nigeria
    • Ezeaka VC, Iroha EO, Akinsulie AO, et al. Anthropometric indices of infants born to HIV-1-infected mothers: a prospective cohort study in Lagos, Nigeria. Int J STD AIDS. 2009;20:545-548.
    • (2009) Int J STD AIDS. , vol.20 , pp. 545-548
    • Ezeaka, V.C.1    Iroha, E.O.2    Akinsulie, A.O.3
  • 14
    • 0025763743 scopus 로고
    • Perinatal transmission of HIV-1: Lack of impact of maternal HIV infection on characteristics of livebirths and on neonatal mortality in Kigali, Rwanda
    • Lepage P, Dabis F, Hitimana DG, et al. Perinatal transmission of HIV-1: lack of impact of maternal HIV infection on characteristics of livebirths and on neonatal mortality in Kigali, Rwanda. AIDS. 1991;5:295-300.
    • (1991) AIDS , vol.5 , pp. 295-300
    • Lepage, P.1    Dabis, F.2    Hitimana, D.G.3
  • 15
    • 7344221468 scopus 로고    scopus 로고
    • Safety of the maternal-infant zidovudine regimen utilized in the Pediatric AIDS Clinical Trial Group 076 Study
    • Sperling RS, Shapiro DE, McSherry GD, et al. Safety of the maternal-infant zidovudine regimen utilized in the Pediatric AIDS Clinical Trial Group 076 Study. AIDS. 1998;12:1805-1813.
    • (1998) AIDS , vol.12 , pp. 1805-1813
    • Sperling, R.S.1    Shapiro, D.E.2    McSherry, G.D.3
  • 16
    • 0033528521 scopus 로고    scopus 로고
    • 6-month efficacy, tolerance, and acceptability of a short regimen of oral zidovudine to reduce vertical transmission of HIV in breastfed children in Côte d'Ivoire and Burkina Faso: A double-blind placebo-controlled multicentre trial
    • DITRAME Study Group. DIminution de la Transmission Mère-Enfant
    • Dabis F, Msellati P, Meda N, et al. 6-month efficacy, tolerance, and acceptability of a short regimen of oral zidovudine to reduce vertical transmission of HIV in breastfed children in Côte d'Ivoire and Burkina Faso: a double-blind placebo-controlled multicentre trial. DITRAME Study Group. DIminution de la Transmission Mère-Enfant. Lancet. 1999;353:786-792.
    • (1999) Lancet. , vol.353 , pp. 786-792
    • Dabis, F.1    Msellati, P.2    Meda, N.3
  • 17
    • 0035227158 scopus 로고    scopus 로고
    • Safety of late in utero exposure to zidovudine in infants born to human immunodeficiency virus-infected mothers: Bangkok
    • Bangkok Collaborative Perinatal HIV Transmission Study Group
    • Chotpitayasunondh T, Vanprapar N, Simonds RJ, et al. Safety of late in utero exposure to zidovudine in infants born to human immunodeficiency virus-infected mothers: Bangkok. Bangkok Collaborative Perinatal HIV Transmission Study Group. Pediatrics. 2001;107:E5.
    • (2001) Pediatrics. , vol.107
    • Chotpitayasunondh, T.1    Vanprapar, N.2    Simonds, R.J.3
  • 18
    • 33645550495 scopus 로고    scopus 로고
    • Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmission
    • Briand N, Le Coeur S, Traisathit P, et al. Growth of human immunodeficiency virus-uninfected children exposed to perinatal zidovudine for the prevention of mother-to-child human immunodeficiency virus transmission. Pediatr Infect Dis J. 2006;25:325-332.
    • (2006) Pediatr Infect Dis J. , vol.25 , pp. 325-332
    • Briand, N.1    Le Coeur, S.2    Traisathit, P.3
  • 19
    • 0032991193 scopus 로고    scopus 로고
    • Is zidovudine therapy in pregnant HIV- infected women associated with gestational age and birthweight?
    • The European Collaborative Study
    • The European Collaborative Study. Is zidovudine therapy in pregnant HIV- infected women associated with gestational age and birthweight? AIDS. 1999;13:119-124.
    • (1999) AIDS , vol.13 , pp. 119-124
  • 20
    • 0036174438 scopus 로고    scopus 로고
    • Assessment of mitochondrial toxicity in human cells treated with tenofovir: Comparison with other nucleoside reverse transcriptase inhibitors
    • Birkus G, Hitchcock MJ, Cihlar T. Assessment of mitochondrial toxicity in human cells treated with tenofovir: comparison with other nucleoside reverse transcriptase inhibitors. Antimicrob Agents Chemother. 2002;46:716-723.
    • (2002) Antimicrob Agents Chemother. , vol.46 , pp. 716-723
    • Birkus, G.1    Hitchcock, M.J.2    Cihlar, T.3
  • 21
    • 1642420304 scopus 로고    scopus 로고
    • Relationship between antiviral activity and host toxicity: Comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine- triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase
    • Feng JY, Murakami E, Zorca SM, et al. Relationship between antiviral activity and host toxicity: comparison of the incorporation efficiencies of 2',3'-dideoxy-5-fluoro-3'-thiacytidine-triphosphate analogs by human immunodeficiency virus type 1 reverse transcriptase and human mitochondrial DNA polymerase. Antimicrob Agents Chemother. 2004;48:1300-1306.
    • (2004) Antimicrob Agents Chemother. , vol.48 , pp. 1300-1306
    • Feng, J.Y.1    Murakami, E.2    Zorca, S.M.3
  • 23
    • 48749127377 scopus 로고    scopus 로고
    • Towards universal access: Scaling up priority HIV/AIDS interventions in the health sector
    • Available at Accessed May 10, 2013
    • WHO. Towards universal access: scaling up priority HIV/AIDS interventions in the health sector. Progress report 2009. Available at: http://www. unaidsrstesa.org/resources/reports/towards-universal-access-scaling-priority- hivaids-interventions-health-sector. Accessed May 10, 2013.
    • WHO Progress Report 2009
  • 24
    • 84858139266 scopus 로고    scopus 로고
    • Global HIV/AIDS response: Epidemic update and health sector progress towards universal access
    • WHO Available at Accessed May 10, 2012
    • WHO. Global HIV/AIDS response: epidemic update and health sector progress towards universal access. Progress report 2011. Available at: http://www.who.int/hiv/pub/progress-report2011/en/. Accessed May 10, 2012.
    • Progress Report 2011
  • 25
    • 84861526377 scopus 로고    scopus 로고
    • Safety of tenofovir use during pregnancy: Early growth outcomes in HIV-exposed uninfected infants
    • Pediatric HIV/AIDS Cohort Study (PHACS)
    • Siberry GK, Williams PL, Mendez H, et al.; Pediatric HIV/AIDS Cohort Study (PHACS). Safety of tenofovir use during pregnancy: early growth outcomes in HIV-exposed uninfected infants. AIDS. 2012;26:1151-1159.
    • (2012) AIDS , vol.26 , pp. 1151-1159
    • Siberry, G.K.1    Williams, P.L.2    Mendez, H.3
  • 26
    • 84891915489 scopus 로고    scopus 로고
    • Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy
    • P1025 Team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group
    • Ransom CE, Huo Y, Patel K, et al.; P1025 Team of the International Maternal Pediatric Adolescent AIDS Clinical Trials Group. Infant growth outcomes after maternal tenofovir disoproxil fumarate use during pregnancy. J Acquir Immune Defic Syndr. 2013;64:374-381.
    • (2013) J Acquir Immune Defic Syndr. , vol.64 , pp. 374-381
    • Ransom, C.E.1    Huo, Y.2    Patel, K.3
  • 27
    • 84861553641 scopus 로고    scopus 로고
    • Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial
    • DART trial team
    • Gibb DM, Kizito H, Russell EC, et al.; DART trial team. Pregnancy and infant outcomes among HIV-infected women taking long-term ART with and without tenofovir in the DART trial. PLoS Med. 2012;9:e1001217.
    • (2012) PLoS Med. , vol.9
    • Gibb, D.M.1    Kizito, H.2    Russell, E.C.3
  • 28
    • 0037071791 scopus 로고    scopus 로고
    • Antiretroviral therapy during pregnancy and the risk of an adverse outcome
    • Tuomala RE, Shapiro DE, Mofenson LM, et al. Antiretroviral therapy during pregnancy and the risk of an adverse outcome. N Engl J Med. 2002;346:1863-1870.
    • (2002) N Engl J Med. , vol.346 , pp. 1863-1870
    • Tuomala, R.E.1    Shapiro, D.E.2    Mofenson, L.M.3
  • 29
    • 0037379462 scopus 로고    scopus 로고
    • Exposure to antiretroviral therapy in utero or early life: The health of uninfected children born to HIV-infected women
    • European Collaborative Study
    • European Collaborative Study. Exposure to antiretroviral therapy in utero or early life: the health of uninfected children born to HIV-infected women. J Acquir Immune Defic Syndr. 2003;32:380-387.
    • (2003) J Acquir Immune Defic Syndr. , vol.32 , pp. 380-387
  • 30
    • 84869066654 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana
    • Chen JY, Ribaudo HJ, Souda S, et al. Highly active antiretroviral therapy and adverse birth outcomes among HIV-infected women in Botswana. J Infect Dis. 2012;206:1695-1705.
    • (2012) J Infect Dis. , vol.206 , pp. 1695-1705
    • Chen, J.Y.1    Ribaudo, H.J.2    Souda, S.3
  • 31
    • 59849097134 scopus 로고    scopus 로고
    • Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire
    • Ekouevi DK, Coffie PA, Becquet R, et al. Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire. AIDS. 2008;22:1815-1820.
    • (2008) AIDS , vol.22 , pp. 1815-1820
    • Ekouevi, D.K.1    Coffie, P.A.2    Becquet, R.3
  • 32
    • 84877113825 scopus 로고    scopus 로고
    • Combination antiretroviral use and preterm birth
    • Pediatric HIV/AIDS Cohort Study
    • Watts DH, Williams PL, Kacanek D, et al.; Pediatric HIV/AIDS Cohort Study. Combination antiretroviral use and preterm birth. J Infect Dis. 2013;207:612-621.
    • (2013) J Infect Dis. , vol.207 , pp. 612-621
    • Watts, D.H.1    Williams, P.L.2    Kacanek, D.3
  • 33
    • 84861918643 scopus 로고    scopus 로고
    • Infant outcomes after maternal antiretroviral exposure in resource-limited settings
    • ACTG 5190/PACTG 1054 Study Team
    • Nielsen-Saines K, Komarow L, Cu-Uvin S, et al.; ACTG 5190/PACTG 1054 Study Team. Infant outcomes after maternal antiretroviral exposure in resource-limited settings. Pediatrics. 2012;129:e1525-e1532.
    • (2012) Pediatrics. , vol.129
    • Nielsen-Saines, K.1    Komarow, L.2    Cu-Uvin, S.3
  • 34
    • 84863696899 scopus 로고    scopus 로고
    • Small-for-gestational-age births in pregnant women with HIV, due to severity of HIV disease, not antiretroviral therapy
    • Aaron E, Bonacquisti A, Mathew L, et al. Small-for-gestational-age births in pregnant women with HIV, due to severity of HIV disease, not antiretroviral therapy. Infect Dis Obstet Gynecol. 2012;2012:135030.
    • (2012) Infect Dis Obstet Gynecol. , vol.2012 , pp. 135030
    • Aaron, E.1    Bonacquisti, A.2    Mathew, L.3
  • 35
    • 0028820778 scopus 로고
    • Maternal HIV infection, drug use, and growth of uninfected children in their first 3 years
    • Ross A, Raab GM, Mok J, et al. Maternal HIV infection, drug use, and growth of uninfected children in their first 3 years. Arch Dis Child. 1995;73:490-495.
    • (1995) Arch Dis Child. , vol.73 , pp. 490-495
    • Ross, A.1    Raab, G.M.2    Mok, J.3
  • 36
    • 17144457068 scopus 로고    scopus 로고
    • Height, weight, and growth in children born to mothers with HIV-1 infection in Europe
    • European Collaborative Study
    • Newell ML, Borja MC, Peckham C; European Collaborative Study. Height, weight, and growth in children born to mothers with HIV-1 infection in Europe. Pediatrics. 2003;111:e52-e60.
    • (2003) Pediatrics. , vol.111
    • Newell, M.L.1    Borja, M.C.2    Peckham, C.3
  • 37
    • 0033550472 scopus 로고    scopus 로고
    • Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Pediatric AIDS Clinical Trials Group Protocol 219/076 Teams
    • Culnane M, Fowler M, Lee SS, et al. Lack of long-term effects of in utero exposure to zidovudine among uninfected children born to HIV-infected women. Pediatric AIDS Clinical Trials Group Protocol 219/076 Teams. JAMA. 1999;281:151-157.
    • (1999) JAMA , vol.281 , pp. 151-157
    • Culnane, M.1    Fowler, M.2    Lee, S.S.3
  • 38
    • 27444441657 scopus 로고    scopus 로고
    • Does exposure to antiretroviral therapy affect growth in the first 18 months of life in uninfected children born to HIV-infected women?
    • European Collaborative Study
    • Hankin C, Thorne C, Newell ML; European Collaborative Study. Does exposure to antiretroviral therapy affect growth in the first 18 months of life in uninfected children born to HIV-infected women? J Acquir Immune Defic Syndr. 2005;40:364-370.
    • (2005) J Acquir Immune Defic Syndr , vol.40 , pp. 364-370
    • Hankin, C.1    Thorne, C.2    Newell, M.L.3
  • 39
    • 70349622497 scopus 로고    scopus 로고
    • Growth of uninfected infants exposed to antiretrovirals born to HIV-infected woman
    • Ibieta MF, Cano JM, Amador JT, et al. [Growth of uninfected infants exposed to antiretrovirals born to HIV-infected woman]. An Pediatr (Barc). 2009;71:299-309.
    • (2009) An Pediatr (Barc). , vol.71 , pp. 299-309
    • Ibieta, M.F.1    Cano, J.M.2    Amador, J.T.3
  • 40
    • 84879417137 scopus 로고    scopus 로고
    • Growth and body composition of uninfected children exposed to human immunodeficiency virus: Comparison with a contemporary cohort and United States National Standards
    • e1
    • Neri D, Somarriba GA, Schaefer NN, et al. Growth and body composition of uninfected children exposed to human immunodeficiency virus: comparison with a contemporary cohort and United States National Standards. J Pediatr. 2013;163:249-54.e1.
    • (2013) J Pediatr. , vol.163 , pp. 249-254
    • Neri, D.1    Somarriba, G.A.2    Schaefer, N.N.3
  • 41
    • 78751618054 scopus 로고    scopus 로고
    • Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana
    • Powis KM, Smeaton L, Ogwu A, et al. Effects of in utero antiretroviral exposure on longitudinal growth of HIV-exposed uninfected infants in Botswana. J Acquir Immune Defic Syndr. 2011;56:131-138.
    • (2011) J Acquir Immune Defic Syndr. , vol.56 , pp. 131-138
    • Powis, K.M.1    Smeaton, L.2    Ogwu, A.3
  • 43
    • 0036232565 scopus 로고    scopus 로고
    • Bone mineral content is lower in prepubertal HIV-infected children
    • Arpadi SM, Horlick M, Thornton J, et al. Bone mineral content is lower in prepubertal HIV-infected children. J Acquir Immune Defic Syndr. 2002;29:450-454.
    • (2002) J Acquir Immune Defic Syndr. , vol.29 , pp. 450-454
    • Arpadi, S.M.1    Horlick, M.2    Thornton, J.3
  • 44
    • 0035964662 scopus 로고    scopus 로고
    • Bone mineral loss through increased bone turnover in HIV-infected children treated with highly active antiretroviral therapy
    • Mora S, Sala N, Bricalli D, et al. Bone mineral loss through increased bone turnover in HIV-infected children treated with highly active antiretroviral therapy. AIDS. 2001;15:1823-1829.
    • (2001) AIDS , vol.15 , pp. 1823-1829
    • Mora, S.1    Sala, N.2    Bricalli, D.3
  • 45
    • 0842313032 scopus 로고    scopus 로고
    • Longitudinal changes of bone mineral density and metabolism in antiretroviral-treated human immunodeficiency virus-infected children
    • Mora S, Zamproni I, Beccio S, et al. Longitudinal changes of bone mineral density and metabolism in antiretroviral-treated human immunodeficiency virus-infected children. J Clin Endocrinol Metab. 2004;89:24-28.
    • (2004) J Clin Endocrinol Metab. , vol.89 , pp. 24-28
    • Mora, S.1    Zamproni, I.2    Beccio, S.3
  • 46
    • 3042848853 scopus 로고    scopus 로고
    • Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral- naive patients: A 3-year randomized trial
    • 903 Study Group
    • Gallant JE, Staszewski S, Pozniak AL, et al.; 903 Study Group. Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral- naive patients: a 3-year randomized trial. JAMA. 2004;292:191-201.
    • (2004) JAMA , vol.292 , pp. 191-201
    • Gallant, J.E.1    Staszewski, S.2    Pozniak, A.L.3
  • 47
    • 44649084952 scopus 로고    scopus 로고
    • Risk factors for decreased bone density and effects of HIV on bone in the elderly
    • Jones S, Restrepo D, Kasowitz A, et al. Risk factors for decreased bone density and effects of HIV on bone in the elderly. Osteoporos Int. 2008;19:913-918.
    • (2008) Osteoporos Int. , vol.19 , pp. 913-918
    • Jones, S.1    Restrepo, D.2    Kasowitz, A.3
  • 48
    • 33749059820 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy: Impact on bone mineral density in HIV-infected children
    • Gafni RI, Hazra R, Reynolds JC, et al. Tenofovir disoproxil fumarate and an optimized background regimen of antiretroviral agents as salvage therapy: impact on bone mineral density in HIV-infected children. Pediatrics. 2006;118:e711-e718.
    • (2006) Pediatrics. , vol.118
    • Gafni, R.I.1    Hazra, R.2    Reynolds, J.C.3
  • 49
    • 40749108414 scopus 로고    scopus 로고
    • Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus
    • Purdy JB, Gafni RI, Reynolds JC, et al. Decreased bone mineral density with off-label use of tenofovir in children and adolescents infected with human immunodeficiency virus. J Pediatr. 2008;152:582-584.
    • (2008) J Pediatr. , vol.152 , pp. 582-584
    • Purdy, J.B.1    Gafni, R.I.2    Reynolds, J.C.3
  • 50
    • 27944475515 scopus 로고    scopus 로고
    • A 12-month treatment with tenofovir does not impair bone mineral accrual in HIV-infected children
    • Giacomet V, Mora S, Martelli L, et al. A 12-month treatment with tenofovir does not impair bone mineral accrual in HIV-infected children. J Acquir Immune Defic Syndr. 2005;40:448-450.
    • (2005) J Acquir Immune Defic Syndr. , vol.40 , pp. 448-450
    • Giacomet, V.1    Mora, S.2    Martelli, L.3
  • 51
    • 0033040847 scopus 로고    scopus 로고
    • Administration of 9-[ 2-®-(phosphonomethoxy)propyl]adenine (PMPA) to gravid and infant rhesus macaques (Macaca mulatta): Safety and efficacy studies
    • Tarantal AF, Marthas ML, Shaw JP, et al. Administration of 9-[ 2-®-(phosphonomethoxy)propyl]adenine (PMPA) to gravid and infant rhesus macaques (Macaca mulatta): safety and efficacy studies. J Acquir Immune Defic Syndr Hum Retrovirol. 1999;20:323-333.
    • (1999) J Acquir Immune Defic Syndr Hum Retrovirol. , vol.20 , pp. 323-333
    • Tarantal, A.F.1    Marthas, M.L.2    Shaw, J.P.3
  • 52
    • 0036500034 scopus 로고    scopus 로고
    • Fetal and maternal outcome after administration of tenofovir to gravid rhesus monkeys (Macaca mulatta)
    • Tarantal AF, Castillo A, Ekert JE, et al. Fetal and maternal outcome after administration of tenofovir to gravid rhesus monkeys (Macaca mulatta). J Acquir Immune Defic Syndr. 2002;29:207-220.
    • (2002) J Acquir Immune Defic Syndr. , vol.29 , pp. 207-220
    • Tarantal, A.F.1    Castillo, A.2    Ekert, J.E.3
  • 53
    • 81255178826 scopus 로고    scopus 로고
    • Exposure to antiretroviral agents during pregnancy does not alter bone status in infants
    • Mora S, Giacomet V, Viganò A, et al. Exposure to antiretroviral agents during pregnancy does not alter bone status in infants. Bone. 2012;50:255-258.
    • (2012) Bone. , vol.50 , pp. 255-258
    • Mora, S.1    Giacomet, V.2    Viganò, A.3
  • 54
    • 83455179365 scopus 로고    scopus 로고
    • In utero exposure to tenofovir disoproxil fumarate does not impair growth and bone health in HIV-uninfected children born to HIV-infected mothers
    • Viganò A, Mora S, Giacomet V, et al. In utero exposure to tenofovir disoproxil fumarate does not impair growth and bone health in HIV-uninfected children born to HIV-infected mothers. Antivir Ther. 2011;16:1259-1266.
    • (2011) Antivir Ther. , vol.16 , pp. 1259-1266
    • Viganò, A.1    Mora, S.2    Giacomet, V.3
  • 55
    • 84902538629 scopus 로고    scopus 로고
    • Study of effects of tenofovir on bone health and kidneys during pregnancy and breastfeeding. Available at Accessed June 5, 2013
    • Study of effects of tenofovir on bone health and kidneys during pregnancy and breastfeeding. Available at: http://clinicaltrials.gov/ct2/show/NCT0106 6858?term=impaact+1077&rank=1. Accessed June 5, 2013.
  • 56
    • 0033604060 scopus 로고    scopus 로고
    • Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues
    • Blanche S, Tardieu M, Rustin P, et al. Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues. Lancet. 1999;354:1084-1089.
    • (1999) Lancet. , vol.354 , pp. 1084-1089
    • Blanche, S.1    Tardieu, M.2    Rustin, P.3
  • 57
    • 0024406638 scopus 로고
    • Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma
    • König H, Behr E, Löwer J, et al. Azidothymidine triphosphate is an inhibitor of both human immunodeficiency virus type 1 reverse transcriptase and DNA polymerase gamma. Antimicrob Agents Chemother. 1989;33:2109-2114.
    • (1989) Antimicrob Agents Chemother. , vol.33 , pp. 2109-2114
    • König, H.1    Behr, E.2    Löwer, J.3
  • 58
    • 0025274663 scopus 로고
    • Mitochondrial myopathy caused by long-term zidovudine therapy
    • Dalakas MC, Illa I, Pezeshkpour GH, et al. Mitochondrial myopathy caused by long-term zidovudine therapy. N Engl J Med. 1990;322:1098-1105.
    • (1990) N Engl J Med. , vol.322 , pp. 1098-1105
    • Dalakas, M.C.1    Illa, I.2    Pezeshkpour, G.H.3
  • 59
    • 0028158398 scopus 로고
    • Cardiac mitochondrial DNA polymerase- gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine
    • Lewis W, Simpson JF, Meyer RR. Cardiac mitochondrial DNA polymerase- gamma is inhibited competitively and noncompetitively by phosphorylated zidovudine. Circ Res. 1994;74:344-348.
    • (1994) Circ Res. , vol.74 , pp. 344-348
    • Lewis, W.1    Simpson, J.F.2    Meyer, R.R.3
  • 60
    • 0026786397 scopus 로고
    • Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA
    • Copeland WC, Chen MS, Wang TS. Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA. J Biol Chem. 1992;267:21459-21464.
    • (1992) J Biol Chem. , vol.267 , pp. 21459-21464
    • Copeland, W.C.1    Chen, M.S.2    Wang, T.S.3
  • 61
    • 0014545828 scopus 로고
    • The enzymatic termination of polydeoxynucleotides by 2',3'- dideoxyadenosine triphosphate
    • Toji L, Cohen SS. The enzymatic termination of polydeoxynucleotides by 2',3'-dideoxyadenosine triphosphate. Proc Natl Acad Sci USA. 1969;63:871-877.
    • (1969) Proc Natl Acad Sci USA. , vol.63 , pp. 871-877
    • Toji, L.1    Cohen, S.S.2
  • 62
    • 0029077056 scopus 로고
    • Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase
    • Eriksson S, Xu B, Clayton DA. Efficient incorporation of anti-HIV deoxynucleotides by recombinant yeast mitochondrial DNA polymerase. J Biol Chem. 1995;270:18929-18934.
    • (1995) J Biol Chem. , vol.270 , pp. 18929-18934
    • Eriksson, S.1    Xu, B.2    Clayton, D.A.3
  • 63
    • 0034192228 scopus 로고    scopus 로고
    • Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine
    • Gerschenson M, Erhart SW, Paik CY, et al. Fetal mitochondrial heart and skeletal muscle damage in Erythrocebus patas monkeys exposed in utero to 3'-azido-3'-deoxythymidine. AIDS Res Hum Retroviruses. 2000;16:635-644.
    • (2000) AIDS Res Hum Retroviruses. , vol.16 , pp. 635-644
    • Gerschenson, M.1    Erhart, S.W.2    Paik, C.Y.3
  • 64
    • 0034209854 scopus 로고    scopus 로고
    • Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria
    • Ewings EL, Gerschenson M, St Claire MC, et al. Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria. J Acquir Immune Defic Syndr. 2000;24:100-105.
    • (2000) J Acquir Immune Defic Syndr. , vol.24 , pp. 100-105
    • Ewings, E.L.1    Gerschenson, M.2    St Claire, M.C.3
  • 65
    • 27144536621 scopus 로고    scopus 로고
    • Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors
    • Divi RL, Leonard SL, Kuo MM, et al. Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors. Cardiovasc Toxicol. 2005;5:333-346.
    • (2005) Cardiovasc Toxicol. , vol.5 , pp. 333-346
    • Divi, R.L.1    Leonard, S.L.2    Kuo, M.M.3
  • 66
    • 84876906224 scopus 로고    scopus 로고
    • Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age
    • Olivero OA, Torres LR, Gorjifard S, et al. Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age. J Infect Dis. 2013;208:244-248.
    • (2013) J Infect Dis. , vol.208 , pp. 244-248
    • Olivero, O.A.1    Torres, L.R.2    Gorjifard, S.3
  • 67
    • 58549094952 scopus 로고    scopus 로고
    • Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1
    • Torres SM, Walker DM, McCash CL, et al. Mutational analysis of the mitochondrial tRNA genes and flanking regions in umbilical cord tissue from uninfected infants receiving AZT-based therapies for prophylaxis of HIV-1. Environ Mol Mutagen. 2009;50:10-26.
    • (2009) Environ Mol Mutagen. , vol.50 , pp. 10-26
    • Torres, S.M.1    Walker, D.M.2    McCash, C.L.3
  • 68
    • 84876926913 scopus 로고    scopus 로고
    • Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination
    • André-Schmutz I, Dal-Cortivo L, Six E, et al. Genotoxic signature in cord blood cells of newborns exposed in utero to a Zidovudine-based antiretroviral combination. J Infect Dis. 2013;208:235-243.
    • (2013) J Infect Dis. , vol.208 , pp. 235-243
    • André-Schmutz, I.1    Dal-Cortivo, L.2    Six, E.3
  • 69
    • 0038078685 scopus 로고    scopus 로고
    • Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers
    • Women and Infants Transmission Study (WITS) Group
    • Poirier MC, Divi RL, Al-Harthi L, et al.; Women and Infants Transmission Study (WITS) Group. Long-term mitochondrial toxicity in HIV-uninfected infants born to HIV-infected mothers. J Acquir Immune Defic Syndr. 2003;33:175-183.
    • (2003) J Acquir Immune Defic Syndr. , vol.33 , pp. 175-183
    • Poirier, M.C.1    Divi, R.L.2    Al-Harthi, L.3
  • 70
    • 2342613668 scopus 로고    scopus 로고
    • Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir
    • Divi RL, Walker VE, Wade NA, et al. Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to Combivir. AIDS. 2004;18:1013-1021.
    • (2004) AIDS , vol.18 , pp. 1013-1021
    • Divi, R.L.1    Walker, V.E.2    Wade, N.A.3
  • 71
    • 0037378552 scopus 로고    scopus 로고
    • Placenta and cord blood mitochondrial DNA toxicity in HIV-infected women receiving nucleoside reverse transcriptase inhibitors during pregnancy
    • Shiramizu B, Shikuma KM, Kamemoto L, et al. Placenta and cord blood mitochondrial DNA toxicity in HIV-infected women receiving nucleoside reverse transcriptase inhibitors during pregnancy. J Acquir Immune Defic Syndr. 2003;32:370-374.
    • (2003) J Acquir Immune Defic Syndr. , vol.32 , pp. 370-374
    • Shiramizu, B.1    Shikuma, K.M.2    Kamemoto, L.3
  • 72
    • 71949085037 scopus 로고    scopus 로고
    • Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women
    • Aldrovandi GM, Chu C, Shearer WT, et al. Antiretroviral exposure and lymphocyte mtDNA content among uninfected infants of HIV-1-infected women. Pediatrics. 2009;124:e1189-e1197.
    • (2009) Pediatrics. , vol.124
    • Aldrovandi, G.M.1    Chu, C.2    Shearer, W.T.3
  • 73
    • 51749113366 scopus 로고    scopus 로고
    • Perinatal exposure to antiretroviral therapy is associated with increased blood mitochondrial DNA levels and decreased mitochondrial gene expression in infants
    • Côté HC, Raboud J, Bitnun A, et al. Perinatal exposure to antiretroviral therapy is associated with increased blood mitochondrial DNA levels and decreased mitochondrial gene expression in infants. J Infect Dis. 2008;198:851-859.
    • (2008) J Infect Dis. , vol.198 , pp. 851-859
    • Côté, H.C.1    Raboud, J.2    Bitnun, A.3
  • 74
    • 44949129640 scopus 로고    scopus 로고
    • Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy
    • AIDS Clinical Trials Group A5084
    • McComsey GA, Kang M, Ross AC, et al.; AIDS Clinical Trials Group A5084. Increased mtDNA levels without change in mitochondrial enzymes in peripheral blood mononuclear cells of infants born to HIV-infected mothers on antiretroviral therapy. HIV Clin Trials. 2008;9:126-136.
    • (2008) HIV Clin Trials. , vol.9 , pp. 126-136
    • McComsey, G.A.1    Kang, M.2    Ross, A.C.3
  • 75
    • 84864584463 scopus 로고    scopus 로고
    • Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords
    • Kunz A, von Wurmb-Schwark N, Sewangi J, et al. Zidovudine exposure in HIV-1 infected Tanzanian women increases mitochondrial DNA levels in placenta and umbilical cords. PLoS One. 2012;7:e41637.
    • (2012) PLoS One. , vol.7
    • Kunz, A.1    Von Wurmb-Schwark, N.2    Sewangi, J.3
  • 76
    • 84855353782 scopus 로고    scopus 로고
    • Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress
    • Ross AC, Leong T, Avery A, et al. Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress. HIV Med. 2012;13:98-106.
    • (2012) HIV Med. , vol.13 , pp. 98-106
    • Ross, A.C.1    Leong, T.2    Avery, A.3
  • 77
    • 33748103186 scopus 로고    scopus 로고
    • Mitochondrial (mt) DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients
    • Maagaard A, Holberg-Petersen M, Kollberg G, et al. Mitochondrial (mt) DNA changes in tissue may not be reflected by depletion of mtDNA in peripheral blood mononuclear cells in HIV-infected patients. Antivir Ther. 2006;11:601-608.
    • (2006) Antivir Ther. , vol.11 , pp. 601-608
    • Maagaard, A.1    Holberg-Petersen, M.2    Kollberg, G.3
  • 78
    • 67649194801 scopus 로고    scopus 로고
    • Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy
    • Gingelmaier A, Grubert TA, Kost BP, et al. Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy. Antivir Ther. 2009;14:331-338.
    • (2009) Antivir Ther. , vol.14 , pp. 331-338
    • Gingelmaier, A.1    Grubert, T.A.2    Kost, B.P.3
  • 79
    • 84873059408 scopus 로고    scopus 로고
    • Abnormal newborn screens and acylcarnitines in HIV-exposed and ARV-exposed infants
    • Kirmse B, Hobbs CV, Peter I, et al. Abnormal newborn screens and acylcarnitines in HIV-exposed and ARV-exposed infants. Pediatr Infect Dis J. 2013;32:146-150.
    • (2013) Pediatr Infect Dis J. , vol.32 , pp. 146-150
    • Kirmse, B.1    Hobbs, C.V.2    Peter, I.3
  • 80
    • 0033604038 scopus 로고    scopus 로고
    • Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
    • Brinkman K, Smeitink JA, Romijn JA, et al. Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy. Lancet. 1999;354:1112-1115.
    • (1999) Lancet. , vol.354 , pp. 1112-1115
    • Brinkman, K.1    Smeitink, J.A.2    Romijn, J.A.3
  • 81
    • 70849087607 scopus 로고    scopus 로고
    • Lactic acidosis in HIV-exposed infants with perinatal exposure to antiretroviral therapy
    • Shah I. Lactic acidosis in HIV-exposed infants with perinatal exposure to antiretroviral therapy. Ann Trop Paediatr. 2009;29:257-261.
    • (2009) Ann Trop Paediatr. , vol.29 , pp. 257-261
    • Shah, I.1
  • 82
    • 16644382547 scopus 로고    scopus 로고
    • Hyperlactatemia in human immunodeficiency virus-uninfected infants who are exposed to antiretrovirals
    • Noguera A, Fortuny C, Muñoz-Almagro C, et al. Hyperlactatemia in human immunodeficiency virus-uninfected infants who are exposed to antiretrovirals. Pediatrics. 2004;114:e598-e603.
    • (2004) Pediatrics. , vol.114
    • Noguera, A.1    Fortuny, C.2    Muñoz-Almagro, C.3
  • 83
    • 33750138097 scopus 로고    scopus 로고
    • Serum lactate levels in infants exposed peripartum to antiretroviral agents to prevent mother- to-child transmission of HIV: Agence Nationale de Recherches sur le SIDA et les Hépatites Virales 1209 study, Abidjan, Ivory Coast
    • Agence Nationale de Recherches Sur le SIDA 1201/1202 Ditrame Plus Study Group
    • Ekouevi DK, Touré R, Becquet R, et al.; Agence Nationale de Recherches Sur le SIDA 1201/1202 Ditrame Plus Study Group. Serum lactate levels in infants exposed peripartum to antiretroviral agents to prevent mother- to-child transmission of HIV: Agence Nationale de Recherches Sur le SIDA et les Hépatites Virales 1209 study, Abidjan, Ivory Coast. Pediatrics. 2006;118:e1071-e1077.
    • (2006) Pediatrics. , vol.118
    • Ekouevi, D.K.1    Touré, R.2    Becquet, R.3
  • 84
    • 81855164872 scopus 로고    scopus 로고
    • Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications
    • Pediatric HIVAIDS Cohort Study
    • Crain MJ, Williams PL, Griner R, et al.; Pediatric HIVAIDS Cohort Study. Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications. Pediatr Infect Dis J. 2011;30:1069-1074.
    • (2011) Pediatr Infect Dis J. , vol.30 , pp. 1069-1074
    • Crain, M.J.1    Williams, P.L.2    Griner, R.3
  • 85
    • 0042232027 scopus 로고    scopus 로고
    • Persistent mitochondrial dysfunction in HIV-1-exposed but uninfected infants: Clinical screening in a large prospective cohort
    • French Perinatal Cohort Study Group
    • Barret B, Tardieu M, Rustin P, et al.; French Perinatal Cohort Study Group. Persistent mitochondrial dysfunction in HIV-1-exposed but uninfected infants: clinical screening in a large prospective cohort. AIDS. 2003;17:1769-1785.
    • (2003) AIDS , vol.17 , pp. 1769-1785
    • Barret, B.1    Tardieu, M.2    Rustin, P.3
  • 86
    • 0034319154 scopus 로고    scopus 로고
    • Nucleoside exposure in the children of HIV-infected women receiving antiretroviral drugs: Absence of clear evidence for mitochondrial disease in children who died before 5 years of age in five United States cohorts
    • The Perinatal Safety Review Working Group
    • The Perinatal Safety Review Working Group. Nucleoside exposure in the children of HIV-infected women receiving antiretroviral drugs: absence of clear evidence for mitochondrial disease in children who died before 5 years of age in five United States cohorts. J Acquir Immune Defic Syndr. 2000;25:261-268.
    • (2000) J Acquir Immune Defic Syndr. , vol.25 , pp. 261-268
  • 87
    • 0033637597 scopus 로고    scopus 로고
    • Drug safety during pregnancy and in infants. Lack of mortality related to mitochondrial dysfunction among perinatally HIV-exposed children in pediatric HIV surveillance
    • Perinatal Safety Review Working Group; State and Local Health Department HIV/AIDS Surveillance Programs
    • Lindegren ML, Rhodes P, Gordon L, et al.; Perinatal Safety Review Working Group; State and Local Health Department HIV/AIDS Surveillance Programs. Drug safety during pregnancy and in infants. Lack of mortality related to mitochondrial dysfunction among perinatally HIV-exposed children in pediatric HIV surveillance. Ann N Y Acad Sci. 2000;918:222-235.
    • (2000) Ann N y Acad Sci. , vol.918 , pp. 222-235
    • Lindegren, M.L.1    Rhodes, P.2    Gordon, L.3
  • 88
    • 74049132363 scopus 로고    scopus 로고
    • Potential confounding of the association between exposure to nucleoside analogues and mitochondrial dysfunction in HIV-uninfected and indeterminate infants
    • Brogly SB, Foca M, Deville JG, et al. Potential confounding of the association between exposure to nucleoside analogues and mitochondrial dysfunction in HIV-uninfected and indeterminate infants. J Acquir Immune Defic Syndr. 2010;53:154-157.
    • (2010) J Acquir Immune Defic Syndr. , vol.53 , pp. 154-157
    • Brogly, S.B.1    Foca, M.2    Deville, J.G.3
  • 89
    • 0034648743 scopus 로고    scopus 로고
    • Absence of cardiac toxicity of zidovudine in infants
    • Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group
    • Lipshultz SE, Easley KA, Orav EJ, et al. Absence of cardiac toxicity of zidovudine in infants. Pediatric Pulmonary and Cardiac Complications of Vertically Transmitted HIV Infection Study Group. N Engl J Med. 2000;343:759-766.
    • (2000) N Engl J Med. , vol.343 , pp. 759-766
    • Lipshultz, S.E.1    Easley, K.A.2    Orav, E.J.3
  • 90
    • 34247609876 scopus 로고    scopus 로고
    • In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children
    • Brogly SB, Ylitalo N, Mofenson LM, et al. In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children. AIDS. 2007;21:929-938. Development
    • (2007) AIDS , vol.21 , pp. 929-938
    • Brogly, S.B.1    Ylitalo, N.2    Mofenson, L.M.3


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