A microchip filter device incorporating slit arrays and 3-D flow for detection of circulating tumor cells using CAV1-EpCAM conjugated microbeads

Biomaterials

Volumn 35, Issue 26, 2014, Pages 7501-7510

  Kim, Yeon Jeong ^a,b   Koo, Gi Bang ^b   Lee, June Young ^d   Moon, Hui Sung ^a,b   Kim, Dong Gun ^c   Lee, Da Gyum ^c   Lee, Ju Yeon ^c   Oh, Jin Ho ^a   Park, Jong Myeon ^a,b   Kim, Minseok S ^d   Woo, Hyun Goo ^c   Kim, Seung Il ^e   Kang, Pilsung ^f   Choi, Wonshik ^f   Sim, Tae Seok ^d   Park, Woong Yang ^b,g   Lee, Jeong Gun ^d   Kim, You Sun ^c  

^a Samsung Advanced Institute of Technology (SAIT)   (South Korea)

^b Samsung Medical Center   (South Korea)

^c Ajou University School of Medicine   (South Korea)

^d SAMSUNG Electronics   (South Korea)

^e Yonsei University College of Medicine   (South Korea)

^f Korea University   (South Korea)

^g Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

3D flow path membrane filter; Caveolin1; CTCs; EMT

Indexed keywords

CHEMICAL DETECTION; CYTOLOGY; DIAGNOSIS; DISEASES; MICROPROCESSOR CHIPS; PATHOLOGY;

CAVEOLIN-1; CIRCULATING TUMOR CELLS; CTCS; EMT; EPITHELIAL CELL ADHESION MOLECULES; HETEROGENEOUS POPULATIONS; ISOLATION AND IDENTIFICATION; MEMBRANE FILTERS;

CELLS;

ALDEHYDE DEHYDROGENASE; BETA ACTIN; CAVEOLIN 1; CD133 ANTIGEN; CD24 ANTIGEN; CYTOKERATIN; EPITHELIAL CELL ADHESION MOLECULE; FIBRONECTIN; HERMES ANTIGEN; MELAMINE; MESSENGER RNA; NANOBEAD; NERVE CELL ADHESION MOLECULE; OCTAMER TRANSCRIPTION FACTOR 4; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VIMENTIN; CELL ADHESION MOLECULE; IMMOBILIZED PROTEIN; TUMOR ANTIGEN; TUMOR-ASSOCIATED ANTIGEN GA733;

ADHERENT CELL; ARTICLE; BLOOD SAMPLING; BREAST CANCER CELL LINE; BREAST METASTASIS; CANCER CELL CULTURE; CANCER PATIENT; CELL FRACTIONATION; CELL HETEROGENEITY; CELL POPULATION; CELL STRUCTURE; CELL VIABILITY; CIRCULATING TUMOR CELL; CLINICAL ARTICLE; CONJUGATION; CONTROLLED STUDY; DOWN REGULATION; EPITHELIAL MESENCHYMAL TRANSITION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HEMATOPOIETIC CELL; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; LUNG CANCER CELL LINE; MCF 7 CELL LINE; MEASUREMENT ACCURACY; MICROARRAY ANALYSIS; MICROARRAY KIT; MICROCHIP ANALYSIS; MICROTECHNOLOGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PHASE CONTRAST MICROSCOPY; PHENOTYPE; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; THREE DIMENSIONAL FLOW MICROCHIP FILTER; UPREGULATION; WESTERN BLOTTING; BLOOD; BREAST TUMOR; CELL SEPARATION; DEVICES; EQUIPMENT DESIGN; FEMALE; FILTRATION; METABOLISM; MICROFLUIDIC ANALYSIS; PATHOLOGY; TUMOR CELL LINE; TUMOR EMBOLISM;

ANTIGENS, NEOPLASM; BREAST NEOPLASMS; CAVEOLIN 1; CELL ADHESION MOLECULES; CELL LINE, TUMOR; CELL SEPARATION; EPITHELIAL-MESENCHYMAL TRANSITION; EQUIPMENT DESIGN; FEMALE; FILTRATION; HUMANS; IMMOBILIZED PROTEINS; MICROFLUIDIC ANALYTICAL TECHNIQUES; NEOPLASTIC CELLS, CIRCULATING;

EID: 84902533337     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.05.039     Document Type: Article

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