Fast multiclonal clusterization of V(D)J recombinations from high-throughput sequencing

BMC Genomics

Volumn 15, Issue 1, 2014, Pages

  Giraud, Mathieu ^a   Salson, Mikaël ^a   Duez, Marc ^a,e   Villenet, Céline ^a   Quief, Sabine ^a,d   Caillault, Aurélie ^b   Grardel, Nathalie ^b   Roumier, Christophe ^b,c   Preudhomme, Claude ^b,c   Figeac, Martin ^a  

^a UNIV LILLE   (France)

^b Functional and Structural Genomic Platform Université Lille 2 IFR 114 ^*  (France)

^c JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^d Cancer Research Institute of Lille   (France)

^e SIRIC OncoLille   (France)

Author keywords

High throughput sequencing; Immunology; Leukemia; Minimal residual disease follow up; Repertoire sequencing; Sequence analysis; V(D)J recombinations

Indexed keywords

DNA; T CELL RECEPTOR GAMMA; T LYMPHOCYTE RECEPTOR; UNCLASSIFIED DRUG;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADAPTIVE IMMUNITY; AMPLICON; ARTICLE; CANCER PATIENT; CLUSTER ANALYSIS; COMPUTER PREDICTION; COMPUTER PROGRAM; DNA EXTRACTION; DNA LIBRARY; GENE REARRANGEMENT; GENETIC ALGORITHM; GENETIC DATABASE; HIDDEN MARKOV MODEL; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOLOGICAL MEMORY; MINIMAL RESIDUAL DISEASE; POLYMERASE CHAIN REACTION; QUANTITATIVE ANALYSIS; VDJ RECOMBINATION; VIDJIL; ALGORITHM; DNA SEQUENCE; GENETICS; NEOPLASM, RESIDUAL; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROCEDURES;

ALGORITHMS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; NEOPLASM, RESIDUAL; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SEQUENCE ANALYSIS, DNA; SOFTWARE; V(D)J RECOMBINATION;

EID: 84902532520     PISSN: None     EISSN: 14712164     Source Type: Journal    
DOI: 10.1186/1471-2164-15-409     Document Type: Article

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