The prevention of ischemia/reperfusion induced oxidative damage by venous blood in rabbit kidneys monitored with biochemical, histopatological and immunohistochemical analysis

Journal of Physiology and Pharmacology

Volumn 65, Issue 3, 2014, Pages 383-392

  Cetin, N ^a   Suleyman, H ^a   Sener, E ^b   Demirci, E ^c   Gundogdu, C ^c   Akcay, F ^c  

^a RECEP TAYYIP ERDOGAN UNIVERSITY   (Turkey)

^b Erzurum Region Education and Research Hospital   (Turkey)

^c ATATÜRK UNIVERSITY   (Turkey)

Author keywords

Blood urea nitrogen; Glutathione; Ischemia reperfusion injury; Melatonin; Oxidative stress; Venous blood; Xanthine oxidase

Indexed keywords

8 HYDROXYGUANINE; CREATININE; GLUTATHIONE; MALONALDEHYDE; MELATONIN; PROTEIN BCL 2; XANTHINE OXIDASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DNA DAMAGE; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; KIDNEY ISCHEMIA; MALE; NECROSIS; NONHUMAN; OXIDATIVE STRESS; PREVALENCE; RABBIT; REPERFUSION INJURY; UREA NITROGEN BLOOD LEVEL; ANIMAL; KIDNEY; KIDNEY VEIN; METABOLISM; PATHOLOGY;

ANIMALS; IMMUNOHISTOCHEMISTRY; KIDNEY; MALE; OXIDATIVE STRESS; RABBITS; RENAL VEINS; REPERFUSION INJURY;

EID: 84902524518     PISSN: 08675910     EISSN: 18991505     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Kren V, Walterova D. Silybin and silymarin - new effects and applications. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2005; 149: 29-41.
2. Parks DA, Williams TK, Beckman JS. Conversion of xanthine dehydrogenase to oxidase in ischemic rat intestine: a reevaluation. Am J Physiol 1988; 254: 768-774.
3. Grace PA. Ischaemia-reperfusion injury. Br J Surg 1994; 81: 637-647.
4. Li C, Jackson RM. Reactive species mechanisms of cellular hypoxia-reoxygenation injury. Am J Physiol Cell Physiol 2002; 282: 227-241.
5. Zimmerman BJ, Granger DN. Reperfusion injury. Surg Clin North Am 1992; 72: 65-83.
6. Lindsay TF, Liauw S, Romaschin AD, Walker PM. The effect of ischemia/reperfusion on adenine nucleotide metabolism and xanthine oxidase production in skeletal muscle. J Va s c S u r g 1990; 12: 8-15.
7. Parks DA, Granger DN. Contributions of ischemia and reperfusion to mucosal lesion formation. Am J Physiol 1986; 250: 749-753.
8. Del Maestro RF. An approach to free radicals in medicine and biology. Acta Physiol Scand Suppl 1980; 492: 153-168.
9. Marnett LJ. Oxyradicals and DNA damage. Carcinogenesis 2000; 21: 361-370.
10. Huang HY, Helzlsouer KJ, Appel LJ. The effects of vitamin C and vitamin E on oxidative DNA damage: results from a randomized controlled trial. Cancer Epidemiol Biomarkers Prev 2000; 9: 647-652.
11. Collard CD, Gelman S. Pathophysiology, clinical manifestations, and prevention of ischemia-reperfusion injury. Anesthesiology 2001; 94: 1133-1138.
12. Orrenius S, Ankarcrona M, Nicotera P. Mechanisms of calcium-related cell death. Adv Neurol 1996; 71: 137-149; discussion 49-51.
13. Widmaier EP, Raff H, Strang KT. Respiratory physiology. In: Vander, Sherman, Luciano's Human Physiology: The Mechanisms of Body Function, EP Widmaier, H Raff, KT Strang (eds.). McGraw- Hill Companies; 2003. pp. 484-489.
14. Reiter RJ. Cytoprotective properties of melatonin: presumed association with oxidative damage and aging. Nutrition 1998; 14: 691-696.
15. Reiter RJ, Tan DX. Melatonin: a novel protective agent against oxidative injury of the ischemic/reperfused heart. Cardiovasc Res 2003; 58: 10-19.
16. Brzezinska-Slebodzinska E, Slebodzinski AB, Styczynska E. Stimulatory effect of melatonin on the 5 '-monodeiodinase activity in the liver, kidney, and brown adipose tissue during the early neonatal period of the rabbit. J Pineal Res 1998; 24: 137-141.
17. Tok A, Sener E, Albayrak A, et al. Effect of mirtazapine on oxidative stress created in rat kidneys by ischemia-reperfusion. Ren Fail 2012; 34: 103-110.
18. Armstrong D. Free radical and antioxidant protocols. Introduction. Methods Mol Biol 1998; 108: 5-8.
19. Mosca F, Fattorini D, Bompadre S, Littarru GP. Assay of coenzyme Q10 in plasma by a single dilution step. Anal Biochem 2002; 305: 49-54.
20. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351-358.
21. Prajda N, Weber G. Malignant transformation-linked imbalance: decreased xanthine oxidase activity in hepatomas. FEBS Lett 1975; 59: 245-249.
22. Sedlak J, Lindsay RH. Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent. Anal Biochem 1968; 25: 192-205.
23. Shigenaga MK, Aboujaoude EN, Chen Q, Ames BN. Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detection. Methods Enzymol 1994; 234: 16-33.
24. Paller MS. The cell biology of reperfusion injury in the kidney. J Invest Med 1994; 42: 632-639.
25. Isaoglu U, Yilmaz M, Calik M, et al. Biochemical and histopathological investigation of the protective effect of disulfiram in ischemia-induced ovary damage. Gynecol Endocrinol 2012; 28: 143-147.
26. Ross D. Glutathione, free radicals and chemotherapeutic agents. Mechanisms of free-radical induced toxicity and glutathione-dependent protection. Pharmacol Ther 1988; 37: 231-249.
27. Meister A, Anderson ME. Glutathione. Annu Rev Biochem 1983; 52: 711-760.
28. Cadet J, Douki T, Gasparutto D, Ravanat JL. Oxidative damage to DNA: formation, measurement and biochemical features. Mutat Res 2003; 531: 5-23.
29. De Martinis BS, De Lourdes Pires Bianchi M. Methodology for urinary 8-hydroxy-2'-deoxyguanosine analysis by HPLC with electrochemical detection. Pharmacol Res 2002; 46: 129-131.
30. Drobnik J, Tosik D, Piera L, et al. Melatonin-induced glycosaminoglycans augmentation in myocardium remote to infarction. J Physiol Pharmacol 2013; 64: 737-744.
31. Gonciarz M, Gonciarz Z, Bielanski W, et al. The effects of long-term melatonin treatment on plasma liver enzymes levels and plasma concentrations of lipids and melatonin in patients with nonalcoholic steatohepatitis: a pilot study. J Physiol Pharmacol 2012; 63: 35-40.
32. Reiter RJ, Rosales-Corral S, Coto-Montes A, et al. The photoperiod, circadian regulation and chronodisruption: the requisite interplay between the suprachiasmatic nuclei and the pineal and gut melatonin. J Physiol Pharmacol 2011; 62: 269-274.
33. Parlakpinar H, Sahna E, Ozer M, Ozugurlu F, Vardi N, Acet A. Physiological and pharmacological concentrations of melatonin protect against cisplatin-induced acute renal injury. J Pineal Res 2002; 33: 161-166.
34. Tan D, Reiter RJ, Chen L, Poeggeler B, Manchester LC, Barlow-Walden LR. Both physiological and pharmacological levels of melatonin reduce DNA adduct formation induced by the carcinogen safrole. Carcinogenesis 1994; 15: 215-218.
35. Cuzzocrea S, Reiter RJ. Pharmacological action of melatonin in shock, inflammation and ischemia/reperfusion injury. Eur J Pharmacology 2001; 426: 1-10.
36. Dickey DT, Muldoon LL, Doolittle ND, Peterson DR, Kraemer DF, Neuwelt EA. Effect of N-acetylcysteine route of administration on chemoprotection against cisplatin-induced toxicity in rat models. Cancer Chemother Pharmacol 2008; 62: 235-241.
37. Siesjo B. Mechanisms of ischemic brain damage. Crit Care Med 1988; 16: 954-963.
38. DiMari J, Megyesi J, Udvarhelyi N, Price P, Davis R, Safirstein R. N-acetyl cysteine ameliorates ischemic renal failure. Am J Physiol 1997; 272: F292-F298.
39. Slusser SO, Grotyohann LW, Martin LF, Scaduto RC. Glutathione catabolism by the ischemic rat kidney. Am J Physiol 1990; 258: F1547-F1553.
40. Tariq M, Morais C, Sobki S, Al Sulaiman M, Al Khader A. N-acetylcysteine attenuates cyclosporin-induced nephrotoxicity in rats. Nephrol Dials Transplant 1999; 14: 923-929.
41. Sutton TA, Molitoris BA. Mechanisms of cellular injury in ischemic acute renal failure. Semin Nephrol 1998; 18: 490-497.
42. Frega NS, DiBona DR, Guertler B, Leaf A. Ischemic renal injury. Kidney Int Suppl 1976; 6: 17-25.
43. Daemen MA, de Vries B, Buurman WA. Apoptosis and inflammation in renal reperfusion injury. Transplantation 2002; 73: 1693-1700.
44. Tsujimoto Y. Role of Bcl-2 family proteins in apoptosis: apoptosomes or mitochondria? Genes Cells 1998; 3: 697-707.
45. Ito T, Deng X, Carr B, May WS. Bcl-2 phosphorylation required for anti-apoptosis function. J Biol Chem 1997; 272: 11671-11673.
46. Fennell DA, Cotter FE. Controlling the mitochondrial gatekeeper for effective chemotherapy. Br J Haematol 2000; 111: 52-60.
47. Sener MT, Sener E, Tok A, et al. A Biochemical and histologic study of lethal cisplatin nephrotoxicity prevention by mirtazapine. Pharmacol Rep 2012; 64: 594-602.