Retraction: Macrophage Colony-Stimulating Factor Augments Tie2-Expressing Monocyte Differentiation, Angiogenic Function, and Recruitment in a Mouse Model of Breast Cancer (PLoS ONE (2014) 9:6 (e98623) DOI: 10.1371/journal.pone.0098623);Macrophage colony-stimulating factor augments Tie2-expressing monocyte differentiation, angiogenic function, and recruitment in a mouse model of breast cancer

PLoS ONE

Volumn 9, Issue 6, 2014, Pages

  Forget, Mary A ^a   Voorhees, Jeffrey L ^a   Cole, Sara L ^a   Dakhlallah, Duaa ^a   Patterson, Ivory L ^a   Gross, Amy C ^a   Moldovan, Leni ^a   Mo, Xiaokui ^a   Evans, Randall ^a   Marsh, Clay B ^a,b   Eubank, Tim D ^a,b  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ANGIOPOIETIN RECEPTOR; CD14 ANTIGEN; COLONY STIMULATING FACTOR 1; HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PHOSPHATIDYLINOSITOL 3 KINASE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIANGIOGENIC ACTIVITY; ARTICLE; BONE MARROW CELL; BREAST CANCER; CANCER GROWTH; CELL DIFFERENTIATION; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; GENE TARGETING; HUMAN; HUMAN CELL; IN VIVO STUDY; MONOCYTE; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION; ANIMAL; BREAST TUMOR; CYTOLOGY; DRUG EFFECTS; METABOLISM;

ANIMALS; ANTIGENS, CD14; BREAST NEOPLASMS; CELL DIFFERENTIATION; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MACROPHAGE COLONY-STIMULATING FACTOR; MICE; MONOCYTES; RECEPTOR, TIE-2;

EID: 84902456985     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0235096     Document Type: Erratum

References (63)

1. Stanley ER (1986) Action of the colony-stimulating factor, CSF1. Ciba Found. Symp. 118, 29-41.
2. Shurtleff SA, Downing JR, Rock CO, Hawkins SA, Roussel MF, et al. (1990) Structural features of the colony-stimulating factor 1 receptor that affect its association with phosphatidylinositol 3-kinase. EMBO J. 9, 2415-2421.
3. Reedijk M, Liu X, van der Geer P, Letwin K, Waterfield MD, et al. (1992) Tyr721 regulates specific binding of the CSF1R kinase insert to PI 3′-kinase SH2 domains: a model for SH2-mediated receptor-target interactions. EMBO J. 11, 1365-1372.
4. Yeung YG, Stanley ER (2003) Proteomic approaches to the analysis of early events in colony-stimulating factor-1 signal transduction. Mol. Cell. Proteomics 2, 1143-1155.
5. Curry JM, Eubank TD, Roberts RD, Wang Y, Pore N et al. (2008) M-CSF signals through the MAPK/ERK pathway via Sp1 to induce VEGF production and induces angiogenesis in vivo. PLoS One 3, e3405.
6. Wang Y, Zeigler MM, Lam GK, Hunter MG, Eubank TD et al. (2007) The role of the NADPH oxidase complex, p38 MAPK, and Akt in regulating human monocyte/macrophage survival. Am. J. Respir. Cell Mol. Biol. 36, 68-77. (Pubitemid 46067709)
7. Du R, Lu KV, Petritsch C, Liu P, Ganss R et al. (2008) HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. Cancer. Cell. 13, 206-220. (Pubitemid 351318372)
8. Bottazzi B, Polentarutti N, Acero R, Balsari A, Boraschi D et al. (1983) Regulation of the macrophage content of neoplasms by chemoattractants. Science 220, 210-212. (Pubitemid 13115270)
9. Orimo A, Gupta PB, Sgroi DC, Arenzana-Seisdedos F, Delaunay T, et al. (2005) Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion. Cell 121, 335-348. (Pubitemid 40692295)
10. Kuziel WA, Morgan SJ, Dawson TC, Griffin S, Smithies O, et al. (1997) Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2. Proc. Natl. Acad. Sci. U. S. A. 94, 12053-12058. (Pubitemid 27467841)
11. Sánchez-Martín L, Estecha A, Samaniego R, Sánchez-Ramón S, Vega MÁ, et al. (2011) The chemokine CXCL12 regulates monocyte-macrophage differentiation and RUNX3 expression. Blood 117, 88-97.
12. Elgert KD, Alleva DG, Mullins DW (1998) Tumor-induced immune dysfunction: the macrophage connection. J. Leukoc. Biol. 64, 275-290. (Pubitemid 28409233)
13. Eubank TD, Galloway M, Montague CM, Waldman WJ, Marsh CB (2003) MCSF induces vascular endothelial growth factor production and angiogenic activity from human monocytes. J. Immunol. 171, 2637-2643. (Pubitemid 37025577)
14. Bergers G, Brekken R, McMahon G, Vu TH, Itoh T et al. (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat. Cell Biol. 2, 737-744.
15. Bingle L, Brown NJ, Lewis CE (2002) The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J. Pathol. 196, 254-265. (Pubitemid 34189413)
16. DeNardo DG, Andreu P, Coussens LM (2010) Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer Metastasis Rev. 29, 309-316.
17. Gordon S, Martinez FO (2010) Alternative activation of macrophages: mechanism and functions. Immunity 32, 593-604.
18. Gordon S (2003) Alternative activation of macrophages. Nat. Rev. Immunol. 3, 23-35.
19. Mantovani A, Allavena P, Sica A (2004) Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression. Eur. J. Cancer 40, 1660-1667. (Pubitemid 38902900)
20. Lin EY, Nguyen AV, Russell RG, Pollard JW (2001) Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy. J. Exp. Med. 193, 727-740.
21. Lin EY, Gouon-Evans V, Nguyen AV, Pollard JW (2002) The macrophage growth factor CSF1 in mammary gland development and tumor progression. J. Mammary Gland Biol. Neoplasia 7, 147-162. (Pubitemid 38420772)
22. Murdoch C, Tazzyman S, Webster S, Lewis CE (2007) Expression of Tie-2 by human monocytes and their responses to angiopoietin-2. J. Immunol. 178, 7405-7411. (Pubitemid 46847468)
23. Venneri MA, De Palma M, Ponzoni M, Pucci F, Scielzo C et al. (2007) Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer. Blood 109, 5276-5285. (Pubitemid 46890548)
24. De Palma M, Venneri MA, Galli R, Sergi Sergi L, Politi LS et al. (2005) Tie2 identifies a hematopoietic lineage of proangiogenic monocytes required for tumor vessel formation and a mesenchymal population of pericyte progenitors. Cancer. Cell. 8, 211-226. (Pubitemid 41317592)
25. De Palma M, Mazzieri R, Politi LS, Pucci F, Zonari E et al. (2008) Tumortargeted interferon-alpha delivery by Tie2-expressing monocytes inhibits tumor growth and metastasis. Cancer. Cell. 14, 299-311.
26. Mazzieri R, Pucci F, Moi D, Zonari E, Ranghetti A et al. (2011) Targeting the ANG2/TIE2 axis inhibits tumor growth and metastasis by impairing angiogenesis and disabling rebounds of proangiogenic myeloid cells. Cancer. Cell. 19, 512-526.
27. Pucci F, Venneri MA, Biziato D, Nonis A, Moi D et al. (2009) A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships. Blood 114, 901-914.
28. Coffelt SB, Tal AO, Scholz A, De Palma M, Patel S et al. (2010) Angiopoietin-2 regulates gene expression in TIE2-expressing monocytes and augments their inherent proangiogenic functions. Cancer Res. 70, 5270-5280.
29. Coffelt SB, Chen YY, Muthana M, Welford AF, Tal AO et al. (2011) Angiopoietin 2 stimulates TIE2-expressing monocytes to suppress T cell activation and to promote regulatory T cell expansion. J. Immunol. 186, 4183-4190.
30. Kubota Y, Takubo K, Shimizu T, Ohno H, Kishi K, et al. (2009) CSF1 inhibition selectively targets pathological angiogenesis and lymphangiogenesis. J. Exp. Med. 206, 1089-1102.
31. Kitaura H, Yoshimatsu M, Fujimura Y, Eguchi T, Kohara H et al. (2008) An anti-c-Fms antibody inhibits orthodontic tooth movement. J. Dent. Res. 87, 396-400.
32. Fleetwood AJ, Lawrence T, Hamilton JA, Cook AD (2007) Granulocytemacrophage colony-stimulating factor (CSF) and macrophage CSF-dependent macrophage phenotypes display differences in cytokine profiles and transcription factor activities: implications for CSF blockade in inflammation. J. Immunol. 178, 5245-5252. (Pubitemid 46595309)
33. Lin EY, Pollard JW (2007) Tumor-associated macrophages press the angiogenic switch in breast cancer. Cancer Res. 67, 5064-5066. (Pubitemid 46997238)
34. Lin EY, Li JF, Gnatovskiy L, Deng Y, Zhu L et al. (2006) Macrophages regulate the angiogenic switch in a mouse model of breast cancer. Cancer Res. 66, 11238-11246. (Pubitemid 46009952)
35. Lewis CE, Leek R, Harris A, McGee JO (1995) Cytokine regulation of angiogenesis in breast cancer: the role of tumor-associated macrophages. J. Leukoc. Biol. 57, 747-751.
36. Wang Y, Keogh RJ, Hunter MG, Mitchell CA, Frey RS, et al. (2004) SHIP2 is recruited to the cell membrane upon macrophage colony-stimulating factor (CSF1) stimulation and regulates CSF1-induced signaling. J. Immunol. 173, 6820-6830. (Pubitemid 39541068)
37. Felcht M, Luck R, Schering A, Seidel P, Srivastava K, et al. (2012) Angiopoietin-2 differentially regulates angiogenesis through TIE2 and integrin signaling. J. Clin. Invest. 122, 1991-2005.
38. Wang JM, Griffin JD, Rambaldi A, Chen ZG, Mantovani A (1998) Induction of monocyte migration by recombinant macrophage colony-stimulating factor. J. Immunol. 141, 575-579.
39. Scholl SM, Lidereau R, de la Rochefordiere A, Le-Nir CC, Mosseri V et al. (1996) Circulating levels of the macrophage colony stimulating factor CSF1 in primary and metastatic breast cancer patients. A pilot study. Breast Cancer Res. Treat. 39, 275-283. (Pubitemid 26278942)
40. Scholl SM, Pallud C, Beuvon F, Hacene K, Stanley ER, et al. (1994) Anticolony-stimulating factor-1 antibody staining in primary breast adenocarcinomas correlates with marked inflammatory cell infiltrates and prognosis. J. Natl. Cancer Inst. 86, 120-126. (Pubitemid 24040150)
41. Varney ML, Olsen KJ, Mosley RL, Singh RK (2005) Paracrine regulation of vascular endothelial growth factor-a expression during macrophage-melanoma cell interaction: role of monocyte chemotactic protein-1 and macrophage colony-stimulating factor. J. Interferon Cytokine Res. 25, 674-683. (Pubitemid 43010522)
42. Jiao M, Nan KJ (2012) Activation of PI3 kinase/Akt/HIF-1alpha pathway contributes to hypoxia-induced epithelial-mesenchymal transition and chemoresistance in hepatocellular carcinoma. Int. J. Oncol. 40, 461-468.
43. Gort EH, Groot AJ, Derks van de Ven TL, van der Groep P, Verlaan I, et al. (2006) Hypoxia-inducible factor-1alpha expression requires PI 3-kinase activity and correlates with Akt1 phosphorylation in invasive breast carcinomas. Oncogene 25, 6123-6127. (Pubitemid 44562410)
44. Jacquel A, Benikhlef N, Paggetti J, Lalaoui N, Guery L, et al. (2009) Colony-stimulating factor-1-induced oscillations in phosphatidylinositol-3 kinase/AKT are required for caspase activation in monocytes undergoing differentiation into macrophages. Blood 114, 3633-3641.
45. Kelley TW, Graham MM, Doseff AI, Pomerantz RW, Lau SM, et al. (1999) Macrophage colony-stimulating factor promotes cell survival through Akt/protein kinase B. J. Biol. Chem. 274, 26393-26398.
46. Dube A, Akbarali Y, Sato TN, Libermann TA, Oettgen P (1999) Role of the Ets transcription factors in the regulation of the vascular-specific Tie2 gene. Circ. Res. 84, 1177-1185. (Pubitemid 29244779)
47. Song H, Suehiro J, Kanki Y, Kawai Y, Inoue K, et al. (2009) Critical role for GATA3 in mediating Tie2 expression and function in large vessel endothelial cells. J. Biol. Chem. 284, 29109-29124.
48. Hu B, Jarzynka MJ, Guo P, Imanishi Y, Schlaepfer DD, et al. (2006) Angiopoietin 2 induces glioma cell invasion by stimulating matrix metalloprotease 2 expression through the alphavbeta1 integrin and focal adhesion kinase signaling pathway. Cancer Res. 66, 775-783. (Pubitemid 43165942)
49. Hu B, Guo P, Fang Q, Tao HQ, Wang D, et al. (2003) Angiopoietin-2 induces human glioma invasion through the activation of matrix metalloprotease-2. Proc. Natl. Acad. Sci. U. S. A. 100, 8904-8909. (Pubitemid 36899196)
50. Ichihara E, Kaneda K, Saito Y, Yamakawa N, Morishita K (2011) Angiopoietin1 contributes to the maintenance of cell quiescence in EVI1(high) leukemia cells. Biochem. Biophys. Res. Commun. 416, 239-245.
51. Ichikawa Y, Pluznik DH, Sachs L (1996) In vitro control of the development of macrophage and granulocyte colonies. Proc. Natl. Acad. Sci.U. S. A. 56, 488-495.
52. Tsutsui S, Inoue H, Yasuda K, Suzuki K, Takeuchi H, et al. (2006) Angiopoietin 2 expression in invasive ductal carcinoma of the breast: its relationship to the VEGF expression and microvessel density. Breast Cancer Res. Treat. 98, 261-266. (Pubitemid 44195595)
53. Engels K, Fox SB, Whitehouse RM, Gatter KC, Harris AL (1997) Up-regulation of thymidine phosphorylase expression is associated with a discrete pattern of angiogenesis in ductal carcinomas in situ of the breast. J. Pathol. 182, 414-420. (Pubitemid 27317206)
54. Condeelis J, Pollard JW (2006) Macrophages: obligate partners for tumor cell migration, invasion, and metastasis. Cell 124, 263-266. (Pubitemid 43121975)
55. Leek RD, Landers R, Fox SB, Ng F, Harris AL, et al. (1998) Association of tumour necrosis factor alpha and its receptors with thymidine phosphorylase expression in invasive breast carcinoma. Br. J. Cancer 77, 2246-2251. (Pubitemid 28263948)
56. Zhu XD, Zhang JB, Zhuang PY, Zhu HG, Zhang W et al. (2008) High expression of macrophage colony-stimulating factor in peritumoral liver tissue is associated with poor survival after curative resection of hepatocellular carcinoma. J. Clin. Oncol. 26, 2707-2716.
57. Fleetwood AJ, Dinh H, Cook AD, Hertzog PJ, Hamilton JA (2009) GCSF1- and CSF1-dependent macrophage phenotypes display differential dependence on type I interferon signaling. J. Leukoc. Biol. 86, 411-421
58. Martinez FO, Gordon S, Locati M, Mantovani A (2006) Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J. Immunol. 177, 7303-7311. (Pubitemid 44715100)
59. Wyckoff J, Wang W, Lin EY, Wang Y, Pixley F, et al. (2004) A paracrine loop between tumor cells and macrophages is required for tumor cell migration in mammary tumors. Cancer Res. 64, 7022-7029. (Pubitemid 39331012)
60. Wyckoff JB, Wang Y, Lin EY, Li JF, Goswami S et al. (2007) Direct visualization of macrophage-assisted tumor cell intravasation in mammary tumors. Cancer Res. 67, 2649-2656. (Pubitemid 46548952)
61. DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, et al. (2009) CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer. Cell. 16, 91-102.
62. He H, Xu J, Warren CM, Duan D, Li X, et al. (2012) Endothelial cells provide an instructive niche for the differentiation and functional polarization of M2-like macrophages. Blood. 120, 3152-62.
63. De Palma M, Naldini L. (2011) Angiopoietin-2 TIEs up macrophages in tumor angiogenesis. Clin Cancer Res. 17, 5226-32.