An anti-c-Fms antibody inhibits orthodontic tooth movement

Journal of Dental Research

Volumn 87, Issue 4, 2008, Pages 396-400

  Kitaura, H ^a   Yoshimatsu, M ^a   Fujimura, Y ^a   Eguchi, T ^a   Kohara, H ^a   Yamaguchi, A ^b   Yoshida, N ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

c fms; Mouse; Orthodontics; Osteoclast; TNF

Indexed keywords

ACID PHOSPHATASE; ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; BIOLOGICAL MARKER; COLONY STIMULATING FACTOR RECEPTOR; IMMUNOGLOBULIN G; ISOENZYME; MONOCLONAL ANTIBODY; TARTRATE-RESISTANT ACID PHOSPHATASE; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL; ANIMAL MODEL; ARTICLE; C57BL MOUSE; CELL DIFFERENTIATION; DRUG ANTAGONISM; DRUG EFFECT; MECHANICAL STRESS; MOUSE; MOUSE STRAIN; OSTEOCLAST; OSTEOLYSIS; PATHOPHYSIOLOGY; PERIODONTAL DISEASE;

ACID PHOSPHATASE; ANIMALS; ANTIBODIES, MONOCLONAL; BIOLOGICAL MARKERS; BONE RESORPTION; CELL DIFFERENTIATION; IMMUNOGLOBULIN G; ISOENZYMES; MICE; MICE, INBRED C57BL; MICE, INBRED STRAINS; MODELS, ANIMAL; OSTEOCLASTS; OSTEOLYSIS; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; STRESS, MECHANICAL; TOOTH MOVEMENT; TUMOR NECROSIS FACTOR-ALPHA;

EID: 42449123141     PISSN: 00220345     EISSN: None     Source Type: Journal    
DOI: 10.1177/154405910808700405     Document Type: Article

References (24)

1. Abu-Amer Y, Ross FP, Edwards J, Teitelbaum SL (1997). Lipopolysaccharide-stimulated osteoclastogenesis is mediated by tumor necrosis factor via its P55 receptor. J Clin Invest 100:1557-1565.
2. Azuma Y, Kaji K, Katogi R, Takeshita S, Kudo A (2000). Tumor necrosis factor-alpha induces differentiation of and bone resorption by osteoclasts. J Biol Chem 275:4858-4864.
3. Chung CJ, Soma K, Rittling SR, Denhardt DT, Hayata T, Nakashima K, et al. (2008). OPN deficiency suppresses appearance of odontoclastic cells and resorption of the tooth root induced by experimental force application. J Cell Physiol 214:614-620
4. Harris DA, Jones AS, Darendeliler MA (2006). Physical properties of root cementum: part 8. Volumetric analysis of root resorption craters after application of controlled intrusive light and heavy orthodontic forces: a microcomputed tomography scan study. Am J Orthod Dentofacial Orthop 130:639-647.
5. Kim N, Kadono Y, Takami M, Lee J, Lee SH, Okada F, et al. (2005). Osteoclast differentiation independent of the TRANCE-RANK-TRAF6 axis. J Exp Med 202:589-595.
6. Kimble RB, Srivastava S, Ross FP, Matayoshi A, Pacifici R (1996). Estrogen deficiency increases the ability of stromal cells to support murine osteoclastogenesis via an interleukin-1 and tumor necrosis factor-mediated stimulation of macrophage colony-stimulating factor production. J Biol Chem 271:28890-28897.
7. Kitaura H, Sands MS, Aya K, Zhou P, Hirayama T, Umgenannt B, et al. (2004). Marrow stromal cells and osteoclast precursors differentially contribute to TNF-alpha-induced osteoclastogenesis in vivo. J Immunol 173:4838-4846.
8. Kitaura H, Zhou P, Kim HJ, Novack DV, Ross FP, Teitelbaum SL (2005). M-CSF mediates TNF-induced inflammatory osteolysis. J Clin Invest 115:3418-3427.
9. Kobayashi K, Takahashi N, Jimi E, Udagawa N, Takami M, Kotake S, et al. (2000). Tumor necrosis factor alpha stimulates osteoclast differentiation by a mechanism independent of the ODF/RANKL-RANK interaction. J Exp Med 191:275-286.
10. Kong YY, Yoshida H, Sarosi I, Tan HL, Timms E, Capparelli C, et al. (1999). OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397:315-323.
11. Lam J, Takeshita S, Barker JE, Kanagawa O, Ross FP, Teitelbaum SL (2000). TNF-alpha induces osteoclastogenesis by direct stimulation of macrophages exposed to permissive levels of RANK ligand. J Clin Invest 106:1481-1488.
12. Lowney JJ, Norton LA, Shafer DM, Rossomando EF (1995). Orthodontic forces increase tumor necrosis factor alpha in the human gingival sulcus. Am J Orthod Dentofacial Orthop 108:519-524.
13. MacEwan DJ (2002). TNF receptor subtype signalling: differences and cellular consequences. Cell Signal 14:477-492.
14. Merkel KD, Erdmann JM, McHugh KP, Abu-Amer Y, Ross FP, Teitelbaum SL (1999). Tumor necrosis factor-alpha mediates orthopedic implant osteolysis. Am J Pathol 154:203-210.
15. Ogasawara T, Yoshimine Y, Kiyoshima T, Kobayashi I, Matsuo K, Akamine A, et al. (2004). In situ expression of RANKL, RANK, osteoprotegerin and cytokines in osteoclasts of rat periodontal tissue. J Periodontal Res 39:42-49.
16. Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, et al. (2002). Osteoclasts are essential for TNF-alpha-mediated joint destruction. J Clin Invest 110:1419-1427.
17. Srivastava S, Weitzmann MN, Kimble RB, Rizzo M, Zahner M, Milbrandt J, et al. (1998). Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1. J Clin Invest 102:1850-1859.
18. Sudo T, Nishikawa S, Ogawa M, Kataoka H, Ohno N, Izawa A, et al. (1995). Functional hierarchy of c-kit and c-fms in intramarrow production of CFU-M. Oncogene 11:2469-2476.
19. Takei I, Takagi M, Ida H, Ogino T, Santavirta S, Konttinen YT (2000). High macrophage-colony stimulating factor levels in synovial fluid of loose artificial hip joints. J Rheumatol 27:894-899.
20. Takeshita S, Kaji K, Kudo A (2000). Identification and characterization of the new osteoclast progenitor with macrophage phenotypes being able to differentiate into mature osteoclasts. J Bone Miner Res 15:1477-1488.
21. Teitelbaum SL (2000). Bone resorption by osteoclasts. Science 289:1504-1508.
22. Uematsu S, Mogi M, Deguchi T (1996). Interleukin (IL)-1 beta, IL-6, tumor necrosis factor-alpha, epidermal growth factor, and beta 2-microglobulin levels are elevated in gingival crevicular fluid during human orthodontic tooth movement. J Dent Res 75:562-567.
23. Yang PT, Kasai H, Xiao WG, Zhao LJ, He LM, Yamashita A, et al. (2006). Increased expression of macrophage colony-stimulating factor in ankylosing spondylitis and rheumatoid arthritis. Ann Rheum Dis 65:1671-1672.
24. Yoshimatsu M, Shibata Y, Kitaura H, Chang X, Moriishi T, Hashimoto F, et al. (2006). Experimental model of tooth movement by orthodontic force in mice and its application to tumor necrosis factor receptor-deficient mice. J Bone Miner Metab 24:20-27.