Genistein inhibits osteoclastic differentiation of RAW 264.7 cells via regulation of ROS production and scavenging

International Journal of Molecular Sciences

Volumn 15, Issue 6, 2014, Pages 10605-10621

  Lee, Sang Hyun ^a   Kim, Jin Kyoung ^a   Jang, Hae Dong ^a  

^a Hannam University   (South Korea)

Author keywords

Genistein; Mitochondrial electron transport chain system; Nox1; Osteoclastic differentiation; Phase II antioxidant enzymes; Reactive oxygen species

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; COPPER ZINC SUPEROXIDE DISMUTASE; GENISTEIN; GLUTATHIONE; HEME OXYGENASE 1; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; REACTIVE OXYGEN METABOLITE; SCAVENGER; SUPEROXIDE; TRANSCRIPTION FACTOR NRF2; OSTEOCLAST DIFFERENTIATION FACTOR; OXIDOREDUCTASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 1; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOTOXICITY; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE ACTIVATION; GENE REPRESSION; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; MTT ASSAY; NONHUMAN; OSTEOCLAST; RADIOIMMUNOPRECIPITATION; RESPIRATORY CHAIN; RNA TRANSLATION; SPECTROFLUOROMETRY; WESTERN BLOTTING; ANIMAL; CELL LINE; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; ELECTRON TRANSPORT; HEPG2 CELL LINE; METABOLISM; MITOCHONDRION; MOUSE;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; ELECTRON TRANSPORT; FREE RADICAL SCAVENGERS; GENISTEIN; HEME OXYGENASE-1; HEP G2 CELLS; HUMANS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; MITOCHONDRIA; NADH, NADPH OXIDOREDUCTASES; NF-E2-RELATED FACTOR 2; OSTEOCLASTS; RANK LIGAND; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE;

EID: 84902352544     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms150610605     Document Type: Article

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