In vitro labelling of muscle type nicotinic receptors using a fluorophore-conjugated pinnatoxin F derivative

Toxicon

Volumn 87, Issue , 2014, Pages 17-25

  Hellyer, Shane D ^a   Selwood, Andrew I ^b   Van Ginkel, Roel ^b   Munday, Rex ^c   Sheard, Phil ^a   Miles, Christopher O ^d,e   Rhodes, Lesley ^b   Kerr, D Steven ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b CAWTHRON INSTITUTE   (New Zealand)

^c RUAKURA RESEARCH CENTRE   (New Zealand)

^d NORWEGIAN VETERINARY INSTITUTE   (Norway)

^e UNIVERSITY OF OSLO   (Norway)

Author keywords

Confocal imaging; Endplate; Fluorescent pinnatoxin; Nicotinic receptors; NMJ

Indexed keywords

ALPHA BUNGAROTOXIN; CHEMICAL COMPOUND; DIAMINOPOLYETHER SPACER; FLUORESCENT DYE; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR BLOCKING AGENT; PINNATOXIN F DERIVATIVE; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN; ALKALOID; PINNATOXIN F; SPIRO COMPOUND;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; CONJUGATION; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; FLUORESCENCE MICROSCOPY; IN VITRO STUDY; IN VIVO STUDY; MALE; MOTOR NERVE; MOUSE; NEUROMUSCULAR BLOCKING; NEUROMUSCULAR SYNAPSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TOXICITY TESTING; ANIMAL; BREATHING MUSCLE; DIAGNOSTIC USE; DRUG EFFECTS; LD 50; METABOLISM; SPRAGUE DAWLEY RAT; SYNTHESIS; TOXICITY; TRANSGENIC MOUSE;

ALKALOIDS; ANIMALS; FLUORESCENT DYES; LETHAL DOSE 50; MALE; MICE; MICE, TRANSGENIC; NEUROMUSCULAR JUNCTION; NICOTINIC ANTAGONISTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; RESPIRATORY MUSCLES; SPIRO COMPOUNDS;

EID: 84902329769     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2014.05.013     Document Type: Article

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