Expression pattern of human ATP-binding cassette transporters in skin

Pharmacology Research and Perspectives

Volumn 1, Issue 1, 2013, Pages

  Takenaka, Saya ^a   Itoh, Tomoo ^a   Fujiwara, Ryoichi ^a  

^a KITASATO UNIVERSITY   (Japan)

Author keywords

ABC transporter; cancer; mRNA expression; skin; toxicology

Indexed keywords

EID: 84902314010     PISSN: None     EISSN: 20521707     Source Type: Journal    
DOI: 10.1002/prp2.5     Document Type: Article

References (37)

1. Arnould I, Schriml LM, Prades C, Lachtermacher-Triunfol M, Schneider T, Maintoux C, et al. (2001). Identifying and characterizing a five-gene cluster of ATP-binding cassette transporters mapping to human chromosome 17q24: a new subgroup within the ABCA subfamily. GeneScreen 1: 157–164.
2. Baron JM, Höller D, Schiffer R, Frankenberg S, Neis M, Merk HF, et al. (2001). Expression of multiple cytochrome p450 enzymes and multidrug resistance-associated transport proteins in human skin keratinocytes. J Invest Dermatol 116: 541–548.
3. Berggren S, Gall C, Wollnitz N, Ekelund M, Karlbom U, Hoogstraate J, et al. (2007). Gene and protein expression of P-glycoprotein, MRP1, MRP2, and CYP3A4 in the small and large human intestine. Mol Pharm 4: 252–257.
4. Borst P, Zelcer N, van Helvoort A (2000). ABC transporters in lipid transport. Biochim Biophys Acta 1486: 128–144.
5. Broccardo C, Luciani M, Chimini G (1999). The ABCA subclass of mammalian transporters. Biochim Biophys Acta 1461: 395–404.
6. Childs S, Yeh RL, Georges E, Ling V (1995). Identification of a sister gene to P-glycoprotein. Cancer Res 55: 2029–2034.
7. Dean M, Hamon Y, Chimini G (2001a). The human ATP-binding cassette (ABC) transporter superfamily. J Lipid Res 42: 1007–1017.
8. Dean M, Rzhetsky A, Allikmets R (2001b). The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 11: 1156–1166.
9. Fritsch PO, Sidoroff A (2000). Drug-induced Stevens–Johnson syndrome/toxic epidermal necrolysis. Am J Clin Dermatol 1: 349–360.
10. Glavinas H, Krajcsi P, Cserepes J, Sarkadi B (2004). The role of ABC transporters in drug resistance, metabolism and toxicity. Curr Drug Deliv 1: 27–42.
11. Harber LC, Baer RL (1972). Pathogenic mechanisms of drug-induced photosensitivity. J Invest Dermatol 58: 327–342.
12. Kaminski WE, Wenzel JJ, Piehler A, Langmann T, Schmitz G (2001). ABCA6, a novel a subclass ABC transporter. Biochem Biophys Res Commun 285: 1295–1301.
13. Kaplan AP (1984). Drug-induced skin disease. J Allergy Clin Immunol 74: 573–579.
14. Kassahun K, Pearson PG, Tang W, McIntosh I, Leung K, Elmore C, et al. (2001). Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission. Chem Res Toxicol 14: 62–70.
15. Kato Y, Miyazaki T, Kano T, Sugiura T, Kubo Y, Tsuji A (2009). Involvement of influx and efflux transport systems in gastrointestinal absorption of celiprolol. J Pharm Sci 98: 2529–2539.
16. Knowles SR, Uetrecht J, Shear NH (2000). Idiosyncratic drug reactions: the reactive metabolite syndromes. Lancet 356: 1587–1591.
17. Koga T, Fujiwara R, Nakajima M, Yokoi T (2011). Toxicological evaluation of acyl glucuronides of nonsteroidal anti-inflammatory drugs using human embryonic kidney 293 cells stably expressing human UDP-glucuronosyltransferase and human hepatocytes. Drug Metab Dispos 39: 54–60.
18. König J, Rost D, Cui Y, Keppler D (1999). Characterization of the human multidrug resistance protein isoform MRP3 localized to the basolateral hepatocyte membrane. Hepatology 29: 1156–1163.
19. Langmann T, Mauerer R, Zahn A, Moehle C, Probst M, Stremmel W, et al. (2003). Real-time reverse transcription-PCR expression profiling of the complete human ATP-binding cassette transporter superfamily in various tissues. Clin Chem 49: 230–238.
20. Lu K, Lee MH, Patel SB (2001). Dietary cholesterol absorption; more than just bile. Trends Endocrinol Metab 12: 314–320.
21. Manautou JE, de Waart DR, Kunne C, Zelcer N, Goedken M, Borst P, et al. (2005). Altered disposition of acetaminophen in mice with a disruption of the Mrp3 gene. Hepatology 42: 1091–1098.
22. Meier Y, Pauli-Magnus C, Zanger UM, Klein K, Schaeffeler E, Nussler AK, et al. (2006). Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver. Hepatology 44: 62–74.
23. Ohtsuki S, Kamoi M, Watanabe Y, Suzuki H, Hori S, Terasaki T (2007). Correlation of induction of ATP-binding cassette transporter A5 (ABCA5) and ABCB1 mRNAs with differentiation state of human colon tumor. Biol Pharm Bull 30: 1144–1146.
24. Rappa G, Lorico A, Liu MC, Kruh GD, Cory AH, Cory JG, et al. (1997). Overexpression of the multidrug resistance genes mdr1, mdr3, and mrp in L1210 leukemia cells resistant to inhibitors of ribonucleotide reductase. Biochem Pharmacol 54: 649–655.
25. Richard M, Drouin R, Beaulieu AD (1998). ABC50, a novel human ATP-binding cassette protein found in tumor necrosis factor-alpha-stimulated synoviocytes. Genomics 53: 137–145.
26. Saiag P, Caumes E, Chosidow O, Revuz J, Roujeau JC (1992). Drug-induced toxic epidermal necrolysis (Lyell syndrome) in patients infected with the human immunodeficiency virus. J Am Acad Dermatol 26: 567–574.
27. Sakaguchi K, Green M, Stock N, Reger TS, Zunic J, King C (2004). Glucuronidation of carboxylic acid containing compounds by UDP-glucuronosyltransferase isoforms. Arch Biochem Biophys 424: 219–225.
28. Schmitz G, Kaminski WE, Orso E (2000). ABC transporters in cellular lipid trafficking. Curr Opin Lipidol 11: 493–501.
29. Schmitz G, Langmann T, Heimerl S (2001). Role of ABCG1 and other ABCG family members in lipid metabolism. J Lipid Res 42: 1513–1520.
30. Shiohara T, Inaoka M, Kano Y (2006). Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpes viruses and antiviral and antidrug immune responses. Allergol Int 55: 1–8.
31. Siddiqui A, Kerb R, Weale ME, Brinkmann U, Smith A, Goldstein DB, et al. (2003). Association of multidrug resistance in epilepsy with a polymorphism in the drug-transporter gene ABCB1. N Engl J Med 348: 1442–1448.
32. Sommers KR, Kong KM, Bui DT, Fruehauf JP, Holcombe RF (2003). Stevens–Johnson syndrome/toxic epidermal necrolysis in a patient receiving concurrent radiation and gemcitabine. Anticancer Drugs 14: 659–662.
33. Staines AG, Coughtrie MW, Burchell B (2004). N-glucuronidation of carbamazepine in human tissues is mediated by UGT2B7. J Pharmacol Exp Ther 311: 1131–1137.
34. Sumida K, Kawana M, Kouno E, Itoh T, Takano S, Narawa T, et al. (2013). Importance of UDP-glucuronosyltransferase 1A1 expression in skin and its induction by ultraviolet B in neonatal hyperbilirubinemia. Mol Pharmacol 84: 1–8.
35. Szakács G, Paterson JK, Ludwig JA, Booth-Genthe C, Gottesman MM (2006). Targeting multidrug resistance in cancer. Nat Rev Drug Discov 5: 219–234.
36. Tsankov N, Angelova I, Kazandjieva J (2000). Drug-induced psoriasis. Recognition and management. Am J Clin Dermatol 1: 159–165.
37. Yamazaki H, Shibata A, Suzuki M, Nakajima M, Shimada N, Guengerich FP, et al. (1999). Oxidation of troglitazone to a quinone-type metabolite catalyzed by cytochrome P-450 2C8 and P-450 3A4 in human liver microsomes. Drug Metab Dispos 27: 1260–1266.