Targeted Metabolomic study indicating glycyrrhizin's protection against acetaminophen-induced liver damage through reversing fatty acid metabolism

Phytotherapy Research

Volumn 28, Issue 6, 2014, Pages 933-936

  Yu, Jian ^a   Jiang, Yang Shen ^a   Jiang, Yuan ^a   Peng, Yan Fang ^a   Sun, Zhuang ^a   Dai, Xiao Nan ^a   Cao, Qiu Ting ^a   Sun, Ying Ming ^a   Han, Jing Chun ^a   Gao, Ya Jie ^b  

^a DALIAN UNIVERSITY   (China)

^b DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

acetaminophen; fatty acids; glycyrrhizin; liver toxicity

Indexed keywords

ACYLCARNITINE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARNITINE OLEATE; GLYCYRRHIZIC ACID; MYRISTOYLCARNITINE; PALMITOLEOYLCARNITINE; PALMITOYLCARNITINE; PARACETAMOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; DRUG TARGETING; ENZYME ACTIVITY; FATTY ACID METABOLISM; LIVER PROTECTION; MALE; METABOLOMICS; MOUSE; NONHUMAN; PRINCIPAL COMPONENT ANALYSIS; TIME OF FLIGHT MASS SPECTROMETRY; TOXIC HEPATITIS; TREATMENT DURATION; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

MUS;

ACETAMINOPHEN; ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARNITINE; CHROMATOGRAPHY, LIQUID; DRUG-INDUCED LIVER INJURY; GLYCYRRHIZIC ACID; LIPID METABOLISM; MALE; MASS SPECTROMETRY; METABOLOME; MICE; MICE, INBRED C57BL;

EID: 84902271402     PISSN: 0951418X     EISSN: 10991573     Source Type: Journal    
DOI: 10.1002/ptr.5072     Document Type: Article

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