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Volumn 75, Issue 7, 2014, Pages 614-620

CD40 expression in renal cell carcinoma is associated with tumor apoptosis, CD8+ T cell frequency and patient survival

Author keywords

Apoptosis; CD40; CD8; Renal cell carcinoma; Survival

Indexed keywords

CD40 ANTIGEN; CD8 ANTIGEN; TUMOR MARKER;

EID: 84902254477     PISSN: 01988859     EISSN: 18791166     Source Type: Journal    
DOI: 10.1016/j.humimm.2014.04.018     Document Type: Article
Times cited : (28)

References (47)
  • 1
    • 0031944607 scopus 로고    scopus 로고
    • CD40 and CD154 in cell-mediated immunity
    • Grewal I.S., Flavell R.A. CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 1998, 16:111-135.
    • (1998) Annu Rev Immunol , vol.16 , pp. 111-135
    • Grewal, I.S.1    Flavell, R.A.2
  • 3
    • 0033697454 scopus 로고    scopus 로고
    • CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal
    • Schulz O., Edwards A.D., Schito M., Aliberti J., Manickasingham S., Sher A., et al. CD40 triggering of heterodimeric IL-12 p70 production by dendritic cells in vivo requires a microbial priming signal. Immunity 2000, 13(4):453-462.
    • (2000) Immunity , vol.13 , Issue.4 , pp. 453-462
    • Schulz, O.1    Edwards, A.D.2    Schito, M.3    Aliberti, J.4    Manickasingham, S.5    Sher, A.6
  • 4
    • 0033912082 scopus 로고    scopus 로고
    • CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily
    • Eliopoulos A.G., Davies C., Knox P.G., Gallagher N.J., Afford S.C., Adams D.H., et al. CD40 induces apoptosis in carcinoma cells through activation of cytotoxic ligands of the tumor necrosis factor superfamily. Mol Cell Biol 2000, 20(15):5503-5515.
    • (2000) Mol Cell Biol , vol.20 , Issue.15 , pp. 5503-5515
    • Eliopoulos, A.G.1    Davies, C.2    Knox, P.G.3    Gallagher, N.J.4    Afford, S.C.5    Adams, D.H.6
  • 5
    • 33644810627 scopus 로고    scopus 로고
    • CD40: a mediator of pro- and anti-inflammatory signals in renal tubular epithelial cells
    • Laxmanan S., Datta D., Geehan C., Briscoe D.M., Pal S. CD40: a mediator of pro- and anti-inflammatory signals in renal tubular epithelial cells. J Am Soc Nephrol 2005, 16(9):2714-2723.
    • (2005) J Am Soc Nephrol , vol.16 , Issue.9 , pp. 2714-2723
    • Laxmanan, S.1    Datta, D.2    Geehan, C.3    Briscoe, D.M.4    Pal, S.5
  • 6
    • 0036087432 scopus 로고    scopus 로고
    • CD40 ligation stimulates MCP-1 and IL-8 production, TRAF6 recruitment, and MAPK activation in proximal tubule cells
    • Li H., Nord E.P. CD40 ligation stimulates MCP-1 and IL-8 production, TRAF6 recruitment, and MAPK activation in proximal tubule cells. Am J Physiol Renal Physiol 2002, 282(6):F1020-F1033.
    • (2002) Am J Physiol Renal Physiol , vol.282 , Issue.6
    • Li, H.1    Nord, E.P.2
  • 7
    • 20844457959 scopus 로고    scopus 로고
    • CD40/CD154 ligation induces mononuclear cell adhesion to human renal proximal tubule cells via increased ICAM-1 expression
    • Li H., Nord E.P. CD40/CD154 ligation induces mononuclear cell adhesion to human renal proximal tubule cells via increased ICAM-1 expression. Am J Physiol Renal Physiol 2005, 289(1):F145-F153.
    • (2005) Am J Physiol Renal Physiol , vol.289 , Issue.1
    • Li, H.1    Nord, E.P.2
  • 8
    • 0031027019 scopus 로고    scopus 로고
    • Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritides
    • Yellin M.J., D'Agati V., Parkinson G., Han A.S., Szema A., Baum D., et al. Immunohistologic analysis of renal CD40 and CD40L expression in lupus nephritis and other glomerulonephritides. Arthritis Rheum 1997, 40(1):124-134.
    • (1997) Arthritis Rheum , vol.40 , Issue.1 , pp. 124-134
    • Yellin, M.J.1    D'Agati, V.2    Parkinson, G.3    Han, A.S.4    Szema, A.5    Baum, D.6
  • 10
    • 0037143792 scopus 로고    scopus 로고
    • Expression of CD154 on renal cell carcinomas and effect on cell proliferation, motility and platelet-activating factor synthesis
    • Bussolati B., Russo S., Deambrosis I., Cantaluppi V., Volpe A., Ferrando U., et al. Expression of CD154 on renal cell carcinomas and effect on cell proliferation, motility and platelet-activating factor synthesis. Int J Cancer 2002, 100(6):654-661.
    • (2002) Int J Cancer , vol.100 , Issue.6 , pp. 654-661
    • Bussolati, B.1    Russo, S.2    Deambrosis, I.3    Cantaluppi, V.4    Volpe, A.5    Ferrando, U.6
  • 11
    • 27744453515 scopus 로고    scopus 로고
    • Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L
    • Lee J.K., Seki N., Sayers T.J., Subleski J., Gruys E.M., Murphy W.J., et al. Constitutive expression of functional CD40 on mouse renal cancer cells: induction of Fas and Fas-mediated killing by CD40L. Cell Immunol 2005, 235(2):145-152.
    • (2005) Cell Immunol , vol.235 , Issue.2 , pp. 145-152
    • Lee, J.K.1    Seki, N.2    Sayers, T.J.3    Subleski, J.4    Gruys, E.M.5    Murphy, W.J.6
  • 12
    • 33646862241 scopus 로고    scopus 로고
    • Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression
    • Shorts L., Weiss J.M., Lee J.K., Welniak L.A., Subleski J., Back T., et al. Stimulation through CD40 on mouse and human renal cell carcinomas triggers cytokine production, leukocyte recruitment, and antitumor responses that can be independent of host CD40 expression. J Immunol 2006, 176(11):6543-6552.
    • (2006) J Immunol , vol.176 , Issue.11 , pp. 6543-6552
    • Shorts, L.1    Weiss, J.M.2    Lee, J.K.3    Welniak, L.A.4    Subleski, J.5    Back, T.6
  • 13
    • 0029835904 scopus 로고    scopus 로고
    • CD40 is a prognostic marker in primary cutaneous malignant melanoma
    • van den Oord J.J., Maes A., Stas M., Nuyts J., Battocchio S., Kasran A., et al. CD40 is a prognostic marker in primary cutaneous malignant melanoma. Am J Pathol 1996, 149(6):1953-1961.
    • (1996) Am J Pathol , vol.149 , Issue.6 , pp. 1953-1961
    • van den Oord, J.J.1    Maes, A.2    Stas, M.3    Nuyts, J.4    Battocchio, S.5    Kasran, A.6
  • 14
    • 70350069890 scopus 로고    scopus 로고
    • Expression of CD40 and CD40L in gastric cancer tissue and its clinical significance
    • Li R., Chen W.C., Pang X.Q., Hua C., Li L., Zhang X.G. Expression of CD40 and CD40L in gastric cancer tissue and its clinical significance. Int J Mol Sci 2009, 10(9):3900-3917.
    • (2009) Int J Mol Sci , vol.10 , Issue.9 , pp. 3900-3917
    • Li, R.1    Chen, W.C.2    Pang, X.Q.3    Hua, C.4    Li, L.5    Zhang, X.G.6
  • 15
    • 49049096326 scopus 로고    scopus 로고
    • Up-regulation of CD40 with juxtacrine activity in human nonsmall lung cancer cells correlates with poor prognosis
    • Ishikawa K., Miyamoto M., Yoshioka T., Kato T., Kaji M., Ohbuchi T., et al. Up-regulation of CD40 with juxtacrine activity in human nonsmall lung cancer cells correlates with poor prognosis. Cancer 2008, 113(3):530-541.
    • (2008) Cancer , vol.113 , Issue.3 , pp. 530-541
    • Ishikawa, K.1    Miyamoto, M.2    Yoshioka, T.3    Kato, T.4    Kaji, M.5    Ohbuchi, T.6
  • 16
    • 84877698867 scopus 로고    scopus 로고
    • Infiltration of CD40-positive tumor-associated macrophages indicates a favorable prognosis in colorectal cancer patients
    • Kinouchi M., Miura K., Mizoi T., Ishida K., Fujibuchi W., Sasaki H., et al. Infiltration of CD40-positive tumor-associated macrophages indicates a favorable prognosis in colorectal cancer patients. Hepatogastroenterology 2012, 60(121).
    • (2012) Hepatogastroenterology , vol.60 , Issue.121
    • Kinouchi, M.1    Miura, K.2    Mizoi, T.3    Ishida, K.4    Fujibuchi, W.5    Sasaki, H.6
  • 17
    • 84870923481 scopus 로고    scopus 로고
    • Monocyte CD40 expression in head and neck squamous cell carcinoma (HNSCC)
    • Sathawane D., Kharat R.S., Halder S., Roy S., Swami R., Patel R., et al. Monocyte CD40 expression in head and neck squamous cell carcinoma (HNSCC). Hum Immunol 2013, 74(1):1-5.
    • (2013) Hum Immunol , vol.74 , Issue.1 , pp. 1-5
    • Sathawane, D.1    Kharat, R.S.2    Halder, S.3    Roy, S.4    Swami, R.5    Patel, R.6
  • 18
    • 79961101225 scopus 로고    scopus 로고
    • Analysis of CD40 expression in breast cancer and its relation to clinicopathological characteristics
    • Slobodova Z., Ehrmann J., Krejci V., Zapletalova J., Melichar B. Analysis of CD40 expression in breast cancer and its relation to clinicopathological characteristics. Neoplasma 2011, 58(3):189-197.
    • (2011) Neoplasma , vol.58 , Issue.3 , pp. 189-197
    • Slobodova, Z.1    Ehrmann, J.2    Krejci, V.3    Zapletalova, J.4    Melichar, B.5
  • 19
    • 0031788449 scopus 로고    scopus 로고
    • CD40 is functionally expressed on human breast carcinomas: variable inducibility by cytokines and enhancement of Fas-mediated apoptosis
    • Wingett D.G., Vestal R.E., Forcier K., Hadjokas N., Nielson C.P. CD40 is functionally expressed on human breast carcinomas: variable inducibility by cytokines and enhancement of Fas-mediated apoptosis. Breast Cancer Res Treat 1998, 50(1):27-36.
    • (1998) Breast Cancer Res Treat , vol.50 , Issue.1 , pp. 27-36
    • Wingett, D.G.1    Vestal, R.E.2    Forcier, K.3    Hadjokas, N.4    Nielson, C.P.5
  • 20
    • 84867571398 scopus 로고    scopus 로고
    • Expression of CD40 and growth-inhibitory activity of CD40 agonist in ovarian carcinoma cells
    • Zhou Y., He J., Gou L.T., Mu B., Liao W.C., Ma C., et al. Expression of CD40 and growth-inhibitory activity of CD40 agonist in ovarian carcinoma cells. Cancer Immunol Immunother 2012, 61(10):1735-1743.
    • (2012) Cancer Immunol Immunother , vol.61 , Issue.10 , pp. 1735-1743
    • Zhou, Y.1    He, J.2    Gou, L.T.3    Mu, B.4    Liao, W.C.5    Ma, C.6
  • 21
    • 51649083689 scopus 로고    scopus 로고
    • Expression of CD40 and growth-inhibitory activity of CD40 ligand in colon cancer ex vivo
    • Wu Y., Wang L., He X., Xu H., Zhou L., Zhao F., et al. Expression of CD40 and growth-inhibitory activity of CD40 ligand in colon cancer ex vivo. Cell Immunol 2008, 253(1-2):102-109.
    • (2008) Cell Immunol , vol.253 , Issue.1-2 , pp. 102-109
    • Wu, Y.1    Wang, L.2    He, X.3    Xu, H.4    Zhou, L.5    Zhao, F.6
  • 22
    • 33947223664 scopus 로고    scopus 로고
    • Prospect of targeting the CD40 pathway for cancer therapy
    • Vonderheide R.H. Prospect of targeting the CD40 pathway for cancer therapy. Clin Cancer Res 2007, 13(4):1083-1088.
    • (2007) Clin Cancer Res , vol.13 , Issue.4 , pp. 1083-1088
    • Vonderheide, R.H.1
  • 23
    • 84874845333 scopus 로고    scopus 로고
    • Agonistic CD40 antibodies and cancer therapy
    • Vonderheide R.H., Glennie M.J. Agonistic CD40 antibodies and cancer therapy. Clin Cancer Res 2013, 19(5):1035-1043.
    • (2013) Clin Cancer Res , vol.19 , Issue.5 , pp. 1035-1043
    • Vonderheide, R.H.1    Glennie, M.J.2
  • 24
    • 33845792555 scopus 로고    scopus 로고
    • Cell profiler: image analysis software for identifying and quantifying cell phenotypes
    • Carpenter A.E., Jones T.R., Lamprecht M.R., Clarke C., Kang I.H., Friman O., et al. Cell profiler: image analysis software for identifying and quantifying cell phenotypes. Genome Biol 2006, 7(10):R100.
    • (2006) Genome Biol , vol.7 , Issue.10
    • Carpenter, A.E.1    Jones, T.R.2    Lamprecht, M.R.3    Clarke, C.4    Kang, I.H.5    Friman, O.6
  • 25
    • 84902251785 scopus 로고    scopus 로고
    • Team RC R: A language and environment for statistical computing. R Foundation for Statistical Computing
    • Team RC (2013) R: A language and environment for statistical computing. R Foundation for Statistical Computing. http://www.R-project.org/.
    • (2013)
  • 26
    • 84878145323 scopus 로고    scopus 로고
    • A self-help program for memory CD8+ T cells: positive feedback via CD40-CD40L signaling as a critical determinant of secondary expansion
    • Shugart J.A., Bambina S., Alice A.F., Montler R., Bahjat K.S. A self-help program for memory CD8+ T cells: positive feedback via CD40-CD40L signaling as a critical determinant of secondary expansion. PLoS ONE 2013, 8(5):e64878.
    • (2013) PLoS ONE , vol.8 , Issue.5
    • Shugart, J.A.1    Bambina, S.2    Alice, A.F.3    Montler, R.4    Bahjat, K.S.5
  • 27
    • 78649676646 scopus 로고    scopus 로고
    • Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade
    • Genega E.M., Ghebremichael M., Najarian R., Fu Y., Wang Y., Argani P., et al. Carbonic anhydrase IX expression in renal neoplasms: correlation with tumor type and grade. Am J Clin Pathol 2010, 134(6):873-879.
    • (2010) Am J Clin Pathol , vol.134 , Issue.6 , pp. 873-879
    • Genega, E.M.1    Ghebremichael, M.2    Najarian, R.3    Fu, Y.4    Wang, Y.5    Argani, P.6
  • 28
    • 0036215615 scopus 로고    scopus 로고
    • CD40 activation in epithelial ovarian carcinoma cells modulates growth, apoptosis, and cytokine secretion
    • Gallagher N.J., Eliopoulos A.G., Agathangelo A., Oates J., Crocker J., Young L.S. CD40 activation in epithelial ovarian carcinoma cells modulates growth, apoptosis, and cytokine secretion. Mol Pathol 2002, 55(2):110-120.
    • (2002) Mol Pathol , vol.55 , Issue.2 , pp. 110-120
    • Gallagher, N.J.1    Eliopoulos, A.G.2    Agathangelo, A.3    Oates, J.4    Crocker, J.5    Young, L.S.6
  • 29
    • 41149132993 scopus 로고    scopus 로고
    • Twelve immunotherapy drugs that could cure cancers
    • Cheever M.A. Twelve immunotherapy drugs that could cure cancers. Immunol Rev 2008, 222:357-368.
    • (2008) Immunol Rev , vol.222 , pp. 357-368
    • Cheever, M.A.1
  • 30
    • 0141456489 scopus 로고    scopus 로고
    • A phase I trial of CD3/CD28-activated T cells (Xcellerated T cells) and interleukin-2 in patients with metastatic renal cell carcinoma
    • Thompson J.A., Figlin R.A., Sifri-Steele C., Berenson R.J., Frohlich M.W. A phase I trial of CD3/CD28-activated T cells (Xcellerated T cells) and interleukin-2 in patients with metastatic renal cell carcinoma. Clin Cancer Res 2003, 9(10 Pt. 1):3562-3570.
    • (2003) Clin Cancer Res , vol.9 , Issue.10 PART 1 , pp. 3562-3570
    • Thompson, J.A.1    Figlin, R.A.2    Sifri-Steele, C.3    Berenson, R.J.4    Frohlich, M.W.5
  • 31
    • 0023115642 scopus 로고
    • A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone
    • Rosenberg S.A., Lotze M.T., Muul L.M., Chang A.E., Avis F.P., Leitman S., et al. A progress report on the treatment of 157 patients with advanced cancer using lymphokine-activated killer cells and interleukin-2 or high-dose interleukin-2 alone. N Engl J Med 1987, 316(15):889-897.
    • (1987) N Engl J Med , vol.316 , Issue.15 , pp. 889-897
    • Rosenberg, S.A.1    Lotze, M.T.2    Muul, L.M.3    Chang, A.E.4    Avis, F.P.5    Leitman, S.6
  • 32
    • 0023880178 scopus 로고
    • Interleukin 2 expanded tumor-infiltrating lymphocytes in human renal cell cancer: isolation, characterization, and antitumor activity
    • Belldegrun A., Muul L.M., Rosenberg S.A. Interleukin 2 expanded tumor-infiltrating lymphocytes in human renal cell cancer: isolation, characterization, and antitumor activity. Cancer Res 1988, 48(1):206-214.
    • (1988) Cancer Res , vol.48 , Issue.1 , pp. 206-214
    • Belldegrun, A.1    Muul, L.M.2    Rosenberg, S.A.3
  • 33
    • 0030036070 scopus 로고    scopus 로고
    • Prognostic factors of peripheral blood lymphocyte subsets in patients with renal cell carcinoma
    • Arima K., Nakagawa M., Yanagawa M., Sugimura Y., Tochigi H., Kawamura J. Prognostic factors of peripheral blood lymphocyte subsets in patients with renal cell carcinoma. Urol Int 1996, 57(1):5-10.
    • (1996) Urol Int , vol.57 , Issue.1 , pp. 5-10
    • Arima, K.1    Nakagawa, M.2    Yanagawa, M.3    Sugimura, Y.4    Tochigi, H.5    Kawamura, J.6
  • 34
    • 0025128367 scopus 로고
    • Immunohistochemical detection of major histocompatibility complex antigens and quantitative analysis of tumour-infiltrating mononuclear cells in renal cell cancer
    • Tomita Y., Nishiyama T., Fujiwara M., Sato S. Immunohistochemical detection of major histocompatibility complex antigens and quantitative analysis of tumour-infiltrating mononuclear cells in renal cell cancer. Br J Cancer 1990, 62(3):354-359.
    • (1990) Br J Cancer , vol.62 , Issue.3 , pp. 354-359
    • Tomita, Y.1    Nishiyama, T.2    Fujiwara, M.3    Sato, S.4
  • 35
    • 2442623312 scopus 로고    scopus 로고
    • High expression of chemokine gene as a favorable prognostic factor in renal cell carcinoma
    • Kondo T., Ito F., Nakazawa H., Horita S., Osaka Y., Toma H. High expression of chemokine gene as a favorable prognostic factor in renal cell carcinoma. J Urol 2004, 171(6 Pt. 1):2171-2175.
    • (2004) J Urol , vol.171 , Issue.6 PART 1 , pp. 2171-2175
    • Kondo, T.1    Ito, F.2    Nakazawa, H.3    Horita, S.4    Osaka, Y.5    Toma, H.6
  • 36
    • 0029852590 scopus 로고    scopus 로고
    • Prognostic value of the immunomonitoring of patients with renal cell carcinoma under therapy with IL-2/IFN-alpha-2 in combination with 5-FU
    • Gohring B., Riemann D., Rebmann U., Heynemann H., Schabel J., Langner J. Prognostic value of the immunomonitoring of patients with renal cell carcinoma under therapy with IL-2/IFN-alpha-2 in combination with 5-FU. Urol Res 1996, 24(5):297-303.
    • (1996) Urol Res , vol.24 , Issue.5 , pp. 297-303
    • Gohring, B.1    Riemann, D.2    Rebmann, U.3    Heynemann, H.4    Schabel, J.5    Langner, J.6
  • 37
    • 0036875904 scopus 로고    scopus 로고
    • Predictive value of CD8highCD57+ lymphocyte subset in interferon therapy of patients with renal cell carcinoma
    • Characiejus D., Pasukoniene V., Kazlauskaite N., Valuckas K.P., Petraitis T., Mauricas M., et al. Predictive value of CD8highCD57+ lymphocyte subset in interferon therapy of patients with renal cell carcinoma. Anticancer Res 2002, 22(6B):3679-3683.
    • (2002) Anticancer Res , vol.22 , Issue.6 B , pp. 3679-3683
    • Characiejus, D.1    Pasukoniene, V.2    Kazlauskaite, N.3    Valuckas, K.P.4    Petraitis, T.5    Mauricas, M.6
  • 38
    • 0031051536 scopus 로고    scopus 로고
    • Can the CD4+/CD8+ ratio predict the outcome of interferon-alpha therapy for renal cell carcinoma?
    • Hernberg M., Muhonen T., Pyrhonen S. Can the CD4+/CD8+ ratio predict the outcome of interferon-alpha therapy for renal cell carcinoma?. Ann Oncol 1997, 8(1):71-77.
    • (1997) Ann Oncol , vol.8 , Issue.1 , pp. 71-77
    • Hernberg, M.1    Muhonen, T.2    Pyrhonen, S.3
  • 39
    • 78449284621 scopus 로고    scopus 로고
    • Prognostic significance of survivin expression in renal cell cancer and its correlation with radioresistance
    • Lei Y., Geng Z., Guo-Jun W., He W., Jian-Lin Y. Prognostic significance of survivin expression in renal cell cancer and its correlation with radioresistance. Mol Cell Biochem 2010, 344(1-2):23-31.
    • (2010) Mol Cell Biochem , vol.344 , Issue.1-2 , pp. 23-31
    • Lei, Y.1    Geng, Z.2    Guo-Jun, W.3    He, W.4    Jian-Lin, Y.5
  • 40
    • 0032410818 scopus 로고    scopus 로고
    • The inhibitors of apoptosis (IAPs) and their emerging role in cancer
    • LaCasse E.C., Baird S., Korneluk R.G., MacKenzie A.E. The inhibitors of apoptosis (IAPs) and their emerging role in cancer. Oncogene 1998, 17(25):3247-3259.
    • (1998) Oncogene , vol.17 , Issue.25 , pp. 3247-3259
    • LaCasse, E.C.1    Baird, S.2    Korneluk, R.G.3    MacKenzie, A.E.4
  • 41
    • 76049124188 scopus 로고    scopus 로고
    • Enhanced tumor radiosensitivity by a survivin dominant-negative mutant
    • Yuan Q.Z., Wang C.T., Mao Y.Q., Zhang P., Shi H.S., Li Z.Y., et al. Enhanced tumor radiosensitivity by a survivin dominant-negative mutant. Oncol Rep 2010, 23(1):97-103.
    • (2010) Oncol Rep , vol.23 , Issue.1 , pp. 97-103
    • Yuan, Q.Z.1    Wang, C.T.2    Mao, Y.Q.3    Zhang, P.4    Shi, H.S.5    Li, Z.Y.6
  • 42
    • 48749089520 scopus 로고    scopus 로고
    • Increased survivin expression confers chemoresistance to tumor-associated endothelial cells
    • Virrey J.J., Guan S., Li W., Schonthal A.H., Chen T.C., Hofman F.M. Increased survivin expression confers chemoresistance to tumor-associated endothelial cells. Am J Pathol 2008, 173(2):575-585.
    • (2008) Am J Pathol , vol.173 , Issue.2 , pp. 575-585
    • Virrey, J.J.1    Guan, S.2    Li, W.3    Schonthal, A.H.4    Chen, T.C.5    Hofman, F.M.6
  • 43
    • 84875511102 scopus 로고    scopus 로고
    • Predictive factors for response to treatment in patients with advanced renal cell carcinoma
    • Muriel Lopez C., Esteban E., Astudillo A., Pardo P., Berros J.P., Izquierdo M., et al. Predictive factors for response to treatment in patients with advanced renal cell carcinoma. Invest New Drugs 2012, 30(6):2443-2449.
    • (2012) Invest New Drugs , vol.30 , Issue.6 , pp. 2443-2449
    • Muriel Lopez, C.1    Esteban, E.2    Astudillo, A.3    Pardo, P.4    Berros, J.P.5    Izquierdo, M.6
  • 44
    • 77952878558 scopus 로고    scopus 로고
    • Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy
    • Stillebroer A.B., Mulders P.F., Boerman O.C., Oyen W.J., Oosterwijk E. Carbonic anhydrase IX in renal cell carcinoma: implications for prognosis, diagnosis, and therapy. Eur Urol 2010, 58(1):75-83.
    • (2010) Eur Urol , vol.58 , Issue.1 , pp. 75-83
    • Stillebroer, A.B.1    Mulders, P.F.2    Boerman, O.C.3    Oyen, W.J.4    Oosterwijk, E.5
  • 45
    • 75349092529 scopus 로고    scopus 로고
    • Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: prognostic and diagnostic potentials
    • Zhou G.X., Ireland J., Rayman P., Finke J., Zhou M. Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: prognostic and diagnostic potentials. Urology 2010, 75(2):257-261.
    • (2010) Urology , vol.75 , Issue.2 , pp. 257-261
    • Zhou, G.X.1    Ireland, J.2    Rayman, P.3    Finke, J.4    Zhou, M.5
  • 46
    • 84877702039 scopus 로고    scopus 로고
    • Carbonic anhydrase IX (CAIX) is not an independent predictor of outcome in patients with clear cell renal cell carcinoma (ccRCC) after long-term follow-up
    • Zhang B.Y., Thompson R.H., Lohse C.M., Dronca R.S., Cheville J.C., Kwon E.D., et al. Carbonic anhydrase IX (CAIX) is not an independent predictor of outcome in patients with clear cell renal cell carcinoma (ccRCC) after long-term follow-up. BJU Int 2013, 111(7):1046-1053.
    • (2013) BJU Int , vol.111 , Issue.7 , pp. 1046-1053
    • Zhang, B.Y.1    Thompson, R.H.2    Lohse, C.M.3    Dronca, R.S.4    Cheville, J.C.5    Kwon, E.D.6
  • 47
    • 29644431786 scopus 로고    scopus 로고
    • Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects
    • Buhtoiarov I.N., Lum H.D., Berke G., Sondel P.M., Rakhmilevich A.L. Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects. J Immunol 2006, 176(1):309-318.
    • (2006) J Immunol , vol.176 , Issue.1 , pp. 309-318
    • Buhtoiarov, I.N.1    Lum, H.D.2    Berke, G.3    Sondel, P.M.4    Rakhmilevich, A.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.