Preparation and evaluation of charged solid lipid nanoparticles of tetrandrine for ocular drug delivery system: Pharmacokinetics, cytotoxicity and cellular uptake studies

Drug Development and Industrial Pharmacy

Volumn 40, Issue 7, 2014, Pages 980-987

  Li, Jiawei ^a,b   Guo, Xiujun ^a,b   Liu, Zhidong ^a,b   Okeke, Chukwunweike Ikechukwu ^a,b   Li, Nan ^a,b   Zhao, Hainan ^a,b   Aggrey, Mike Okweesi ^a,b   Pan, Weisan ^c   Wu, Tao ^d  

^a BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^b TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^c SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^d Institute of Double Crane   (China)

Author keywords

Cellular uptake; Cytotoxicity; Ocular solid lipid nanoparticles; Pharmacokinetics; Tetrandrine

Indexed keywords

CALCEIN; SOLID LIPID NANOPARTICLE; TETRANDRINE; BENZYLISOQUINOLINE DERIVATIVE; DRUG CARRIER; EYE DROPS; LIPID; NANOPARTICLE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIFFERENTIAL SCANNING CALORIMETRY; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG UPTAKE; EMULSION; ENCAPSULATION; EVAPORATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PARTICLE SIZE; TEMPERATURE; X RAY DIFFRACTION; ZETA POTENTIAL; ANIMAL; CELL LINE; CELL SURVIVAL; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG FORMULATION; EPITHELIUM CELL; EYE; INTRAOCULAR DRUG ADMINISTRATION; METABOLISM; MICRODIALYSIS; PROCEDURES; RABBIT; SURFACE PROPERTY; TOXICITY; TRANSMISSION ELECTRON MICROSCOPY;

ADMINISTRATION, OPHTHALMIC; ANIMALS; BENZYLISOQUINOLINES; CALORIMETRY, DIFFERENTIAL SCANNING; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG CARRIERS; DRUG COMPOUNDING; DRUG LIBERATION; EPITHELIAL CELLS; EYE; FLOW CYTOMETRY; HUMANS; LIPIDS; MICRODIALYSIS; MICROSCOPY, ELECTRON, TRANSMISSION; NANOPARTICLES; OPHTHALMIC SOLUTIONS; PARTICLE SIZE; RABBITS; SURFACE PROPERTIES;

EID: 84902241711     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2013.795582     Document Type: Article

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