Design and synthesis of novel 1,2,3-triazole derivatives of coronopilin as anti-cancer compounds

European Journal of Medicinal Chemistry

Volumn 82, Issue , 2014, Pages 255-262

  Khazir, Jabeena ^b   Hyder, Irfan ^a   Gayatri, J Laxmi ^a   Prasad Yandrati, Leela ^a   Nalla, Naresh ^a   Chasoo, Gousia ^b   Mahajan, Ajay ^b   Saxena, A K ^b   Alam, M S ^c   Qazi, G N ^c   Sampath Kumar, Halmuthur M ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c HAMDARD UNIVERSITY   (India)

Author keywords

1,2,3 Triazole; Coronopilin; NF B (p65) inhibitors; Parthenin; Sesquiterpenoid lactone

Indexed keywords

1,2,3 TRIAZOLE CORONOPILIN DERIVATIVE; 1,2,3 TRIAZOLE DERIVATIVE; ANTINEOPLASTIC AGENT; DOXORUBICIN; FLUOROURACIL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOMYCIN; PARTHENIN; UNCLASSIFIED DRUG; AZULENE DERIVATIVE; CORONOPILIN; SESQUITERPENE; TRIAZOLE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER CELL LINE; CELL CYCLE G1 PHASE; CLICK CHEMISTRY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SYNTHESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HELA CELL LINE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IC 50; IN VITRO STUDY; LEUKEMIA CELL LINE; LUNG CANCER CELL LINE; MCF 7 CELL LINE; PROSTATE CANCER CELL LINE; WESTERN BLOTTING; CELL PROLIFERATION; CHEMICAL STRUCTURE; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; AZULENES; CELL LINE, TUMOR; CELL PROLIFERATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DESIGN; DRUG SCREENING ASSAYS, ANTITUMOR; HELA CELLS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; SESQUITERPENES; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 84902192717     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.05.053     Document Type: Article

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