메뉴 건너뛰기




Volumn 171, Issue 13, 2014, Pages 3171-3181

Ginsenoside Rb3 attenuates oxidative stress and preserves endothelial function in renal arteries from hypertensive rats

Author keywords

endothelial dysfunction; ginsenoside Rb3; hypertension; oxidative stress; renal artery

Indexed keywords

ANTIOXIDANT; GINSENOSIDE; GINSENOSIDE RB 3; LOSARTAN; NITRIC OXIDE; PROTEIN P67; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; UNCLASSIFIED DRUG; ANGIOTENSIN II; GINSENOSIDE RB3; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

EID: 84902145696     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12660     Document Type: Article
Times cited : (58)

References (24)
  • 2
    • 84865772636 scopus 로고    scopus 로고
    • Anti-diabetic effect of ginsenoside Rb(3) in alloxan-induced diabetic mice
    • Bu QT, Zhang WY, Chen QC, Zhang CZ, Gong XJ, Liu WC, et al. (2012). Anti-diabetic effect of ginsenoside Rb(3) in alloxan-induced diabetic mice. Med Chem 8: 934-941.
    • (2012) Med Chem , vol.8 , pp. 934-941
    • Bu, Q.T.1    Zhang, W.Y.2    Chen, Q.C.3    Zhang, C.Z.4    Gong, X.J.5    Liu, W.C.6
  • 3
    • 0029853361 scopus 로고    scopus 로고
    • Cardiovascular protection by ginsenosides and their nitric oxide releasing action
    • Chen X, (1996). Cardiovascular protection by ginsenosides and their nitric oxide releasing action. Clin Exp Pharmacol Physiol 23: 728-732.
    • (1996) Clin Exp Pharmacol Physiol , vol.23 , pp. 728-732
    • Chen, X.1
  • 4
    • 84865663428 scopus 로고    scopus 로고
    • Calcitriol protects renovascular function in hypertension by down-regulating angiotensin II type 1 receptors and reducing oxidative stress
    • Dong J, Wong SL, Lau CW, Lee HK, Ng CF, Zhang L, et al. (2012). Calcitriol protects renovascular function in hypertension by down-regulating angiotensin II type 1 receptors and reducing oxidative stress. Eur Heart J 33: 2980-2990.
    • (2012) Eur Heart J , vol.33 , pp. 2980-2990
    • Dong, J.1    Wong, S.L.2    Lau, C.W.3    Lee, H.K.4    Ng, C.F.5    Zhang, L.6
  • 5
    • 83455245428 scopus 로고    scopus 로고
    • Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model
    • Fang F, Chen X, Huang T, Lue LF, Luddy JS, Yan SS, (2012). Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model. Biochim Biophys Acta 1822: 286-292.
    • (2012) Biochim Biophys Acta , vol.1822 , pp. 286-292
    • Fang, F.1    Chen, X.2    Huang, T.3    Lue, L.F.4    Luddy, J.S.5    Yan, S.S.6
  • 6
    • 79958056715 scopus 로고    scopus 로고
    • Endothelium-mediated control of vascular tone: COX-1 and COX-2 products
    • Félétou M, Huang Y, Vanhoutte PM, (2011). Endothelium-mediated control of vascular tone: COX-1 and COX-2 products. Br J Pharmacol 164: 894-912.
    • (2011) Br J Pharmacol , vol.164 , pp. 894-912
    • Félétou, M.1    Huang, Y.2    Vanhoutte, P.M.3
  • 7
    • 77954326944 scopus 로고    scopus 로고
    • NC3Rs Reporting Guidelines Working Group
    • Kilkenny, Browne, Cuthill, Emerson, Altman; 2010)
    • Kilkenny, Browne, Cuthill, Emerson, Altman; 2010), Kilkenny C, Browne W, Cuthill IC, Emerson M, Altman DG, (2010). NC3Rs Reporting Guidelines Working Group. Br J Pharmacol 160: 1577-1579.
    • (2010) Br J Pharmacol , vol.160 , pp. 1577-1579
    • Kilkenny, C.1    Browne, W.2    Cuthill, I.C.3    Emerson, M.4    Altman, D.G.5
  • 8
    • 60149102407 scopus 로고    scopus 로고
    • Does reversal of oxidative stress and inflammation provide vascular protection?
    • Koh KK, Oh PC, Quon MJ, (2009). Does reversal of oxidative stress and inflammation provide vascular protection? Cardiovasc Res 81: 649-659.
    • (2009) Cardiovasc Res , vol.81 , pp. 649-659
    • Koh, K.K.1    Oh, P.C.2    Quon, M.J.3
  • 9
    • 77955366413 scopus 로고    scopus 로고
    • Inhibitory activity of ginsenosides isolated from processed ginseng on platelet aggregation
    • Lee JG, Lee YY, Wu B, Kim SY, Lee YJ, Yun-Choi HS, et al. (2010). Inhibitory activity of ginsenosides isolated from processed ginseng on platelet aggregation. Pharmazie 65: 520-522.
    • (2010) Pharmazie , vol.65 , pp. 520-522
    • Lee, J.G.1    Lee, Y.Y.2    Wu, B.3    Kim, S.Y.4    Lee, Y.J.5    Yun-Choi, H.S.6
  • 10
    • 34248590312 scopus 로고    scopus 로고
    • Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor
    • Leung KW, Leung FP, Huang Y, Mak NK, Wong RN, (2007). Non-genomic effects of ginsenoside-Re in endothelial cells via glucocorticoid receptor. FEBS Lett 581: 2423-2428.
    • (2007) FEBS Lett , vol.581 , pp. 2423-2428
    • Leung, K.W.1    Leung, F.P.2    Huang, Y.3    Mak, N.K.4    Wong, R.N.5
  • 11
    • 65349185491 scopus 로고    scopus 로고
    • Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells
    • Leung KW, Leung FP, Mak NK, Tombran-Tink J, Huang Y, Wong RNS, (2009). Protopanaxadiol and protopanaxatriol bind to glucocorticoid and oestrogen receptors in endothelial cells. Br J Pharmacol 156: 626-637.
    • (2009) Br J Pharmacol , vol.156 , pp. 626-637
    • Leung, K.W.1    Leung, F.P.2    Mak, N.K.3    Tombran-Tink, J.4    Huang, Y.5    Wong, R.N.S.6
  • 13
    • 77954331629 scopus 로고    scopus 로고
    • Guidelines for reporting experiments involving animals: The ARRIVE guidelines
    • McGrath J, Drummond G, Kilkenny C, Wainwright C, (2010). Guidelines for reporting experiments involving animals: the ARRIVE guidelines. Br J Pharmacol 160: 1573-1576.
    • (2010) Br J Pharmacol , vol.160 , pp. 1573-1576
    • McGrath, J.1    Drummond, G.2    Kilkenny, C.3    Wainwright, C.4
  • 14
    • 84862806848 scopus 로고    scopus 로고
    • Panax notoginseng and its components decreased hypertension via stimulation of endothelial-dependent vessel dilatation
    • Pan C, Huo Y, An X, Singh G, Chen M, Yang Z, et al. (2012). Panax notoginseng and its components decreased hypertension via stimulation of endothelial-dependent vessel dilatation. Vascul Pharmacol 56: 150-158.
    • (2012) Vascul Pharmacol , vol.56 , pp. 150-158
    • Pan, C.1    Huo, Y.2    An, X.3    Singh, G.4    Chen, M.5    Yang, Z.6
  • 15
    • 80051499883 scopus 로고    scopus 로고
    • Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats
    • Shi Y, Han B, Yu X, Qu S, Sui D, (2011). Ginsenoside Rb3 ameliorates myocardial ischemia-reperfusion injury in rats. Pharm Biol 49: 900-906.
    • (2011) Pharm Biol , vol.49 , pp. 900-906
    • Shi, Y.1    Han, B.2    Yu, X.3    Qu, S.4    Sui, D.5
  • 17
    • 77952675244 scopus 로고    scopus 로고
    • Effect of ginsenoside Rb3 on myocardial injury and heart function impairment induced by isoproterenol in rats
    • Wang T, Yu X, Qu S, Xu H, Han B, Sui D, (2010a). Effect of ginsenoside Rb3 on myocardial injury and heart function impairment induced by isoproterenol in rats. Eur J Pharmacol 636: 121-125.
    • (2010) Eur J Pharmacol , vol.636 , pp. 121-125
    • Wang, T.1    Yu, X.2    Qu, S.3    Xu, H.4    Han, B.5    Sui, D.6
  • 18
    • 77954695980 scopus 로고    scopus 로고
    • Ginsenoside Rb3 inhibits angiotensin II-induced vascular smooth muscle cells proliferation
    • Wang T, Yu XF, Qu SC, Xu HL, Sui DY, (2010b). Ginsenoside Rb3 inhibits angiotensin II-induced vascular smooth muscle cells proliferation. Basic Clin Pharmacol Toxicol 107: 685-689.
    • (2010) Basic Clin Pharmacol Toxicol , vol.107 , pp. 685-689
    • Wang, T.1    Yu, X.F.2    Qu, S.C.3    Xu, H.L.4    Sui, D.Y.5
  • 19
    • 77958496539 scopus 로고    scopus 로고
    • Bone morphogenic protein-4 impairs endothelial function through oxidative stress-dependent cyclooxygenase-2 upregulation: Implications on hypertension
    • Wong WT, Tian XY, Chen YC, Leung FP, Liu LM, Lee HK, et al. (2010a). Bone morphogenic protein-4 impairs endothelial function through oxidative stress-dependent cyclooxygenase-2 upregulation: implications on hypertension. Circ Res 107: 984-U995.
    • (2010) Circ Res , vol.107
    • Wong, W.T.1    Tian, X.Y.2    Chen, Y.C.3    Leung, F.P.4    Liu, L.M.5    Lee, H.K.6
  • 20
    • 77951737282 scopus 로고    scopus 로고
    • Endothelial dysfunction: The common consequence in diabetes and hypertension
    • Wong WT, Wong SL, Tian XY, Huang Y, (2010b). Endothelial dysfunction: the common consequence in diabetes and hypertension. J Cardiovasc Pharmacol 55: 300-307.
    • (2010) J Cardiovasc Pharmacol , vol.55 , pp. 300-307
    • Wong, W.T.1    Wong, S.L.2    Tian, X.Y.3    Huang, Y.4
  • 21
    • 79960018147 scopus 로고    scopus 로고
    • Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice
    • Wong WT, Tian XY, Xu A, Yu J, Lau CW, Hoo RL, et al. (2011). Adiponectin is required for PPARγ-mediated improvement of endothelial function in diabetic mice. Cell Metab 14: 104-115.
    • (2011) Cell Metab , vol.14 , pp. 104-115
    • Wong, W.T.1    Tian, X.Y.2    Xu, A.3    Yu, J.4    Lau, C.W.5    Hoo, R.L.6
  • 22
    • 79960025353 scopus 로고    scopus 로고
    • Ginsenoside Rd attenuates redox imbalance and improves stroke outcome after focal cerebral ischemia in aged mice
    • Ye R, Kong X, Yang Q, Zhang Y, Han J, Zhao G, (2011). Ginsenoside Rd attenuates redox imbalance and improves stroke outcome after focal cerebral ischemia in aged mice. Neuropharmacology 61: 815-824.
    • (2011) Neuropharmacology , vol.61 , pp. 815-824
    • Ye, R.1    Kong, X.2    Yang, Q.3    Zhang, Y.4    Han, J.5    Zhao, G.6
  • 23
    • 18844457413 scopus 로고    scopus 로고
    • Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries
    • Zhou W, Chai H, Lin PH, Lumsden AB, Yao Q, Chen C, (2005). Ginsenoside Rb1 blocks homocysteine-induced endothelial dysfunction in porcine coronary arteries. J Vasc Surg 41: 861-868.
    • (2005) J Vasc Surg , vol.41 , pp. 861-868
    • Zhou, W.1    Chai, H.2    Lin, P.H.3    Lumsden, A.B.4    Yao, Q.5    Chen, C.6
  • 24
    • 84856229622 scopus 로고    scopus 로고
    • Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia
    • Zhu J, Jiang Y, Wu L, Lu T, Xu G, Liu X, (2012). Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia. Neuroscience 202: 342-351.
    • (2012) Neuroscience , vol.202 , pp. 342-351
    • Zhu, J.1    Jiang, Y.2    Wu, L.3    Lu, T.4    Xu, G.5    Liu, X.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.