Anti-inflammatory activity of compounds isolated from Astragalus sinicus L. in cytokine-induced keratinocytes and skin

Experimental and Molecular Medicine

Volumn 46, Issue 3, 2014, Pages

  Kim, Byung Hak ^a   Oh, Ikhoon ^b   Kim, Jung Ho ^a   Jeon, Ju Eun ^b   Jeon, Byeongwook ^a   Shin, Jongheon ^b   Kim, Tae Yoon ^a  

^a The Catholic University of Korea   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Astragalus sinicus L.; Immune response; Inflammation; JAK STAT; NF B; PI3 Akt

Indexed keywords

ANTIINFLAMMATORY AGENT; ASTRAGALUS SINICUS EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; JANUS KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PLANT MEDICINAL PRODUCT; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; RF3; RF4; STAT PROTEIN; UNCLASSIFIED DRUG; INTERLEUKIN 23;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTRAGALUS PLANT; ASTRAGALUS SINICUS; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONTROLLED STUDY; DERMATITIS; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; HUMAN; HUMAN CELL; IMMUNE RESPONSE; KERATINOCYTE; LEGUME; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; T LYMPHOCYTE; ANIMAL; C57BL MOUSE; CELL LINE; CHEMISTRY; DRUG EFFECT; ISOLATION AND PURIFICATION; METABOLISM; SKIN;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ASTRAGALUS PLANT; CELL LINE; DERMATITIS; HUMANS; INTERLEUKIN-23; JANUS KINASES; KERATINOCYTES; MICE; MICE, INBRED C57BL; NF-KAPPA B; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SKIN; STAT TRANSCRIPTION FACTORS;

EID: 84902144495     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.1038/emm.2013.157     Document Type: Article

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