Pivotal role for the ubiquitin Y59-E51 loop in lysine 48 polyubiquitination

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 23, 2014, Pages 8434-8439

  Chong, Robert A ^a   Wu, Kenneth ^a   Spratt, Donald E ^b   Yang, Yingying ^c   Lee, Chan ^a   Nayak, Jaladhi ^a   Xu, Ming ^d   Elkholi, Rana ^a   Tappin, Inger ^e   Li, Jessica ^a   Hurwitz, Jerard ^e   Brown, Brian D ^a   Chipuk, Jerry Edward ^a   Chen, Zhijian J ^d   Sanchez, Roberto ^a   Shaw, Gary S ^b   Huang, Lan ^c   Pan, And Zhen Qiang ^a,f  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b WESTERN UNIVERSITY   (Canada)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^f XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

E2 ubiquitin conjugating enzyme; E3 ubiquitin ligase; Receptor ubiquitin

Indexed keywords

CDC34 ENZYME; LYSINE; UBIQUITIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN PROTEIN LIGASE E3; UBIQUITIN Y59 E51; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; POLYUBIQUITINATION; PRIORITY JOURNAL; UBIQUITINATION;

E2 UBIQUITIN-CONJUGATING ENZYME; E3 UBIQUITIN LIGASE; RECEPTOR UBIQUITIN;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; APOPTOSIS; BIOCATALYSIS; CELL LINE, TUMOR; HEK293 CELLS; HUMANS; HYDROGEN BONDING; IMMUNOBLOTTING; LYSINE; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; POLYUBIQUITIN; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RNA INTERFERENCE; SKP CULLIN F-BOX PROTEIN LIGASES; UBIQUITIN; UBIQUITIN-CONJUGATING ENZYMES; UBIQUITINATION;

EID: 84902143589     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1407849111     Document Type: Article

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