Anti-tumor properties of orally administered glucosamine and N-acetyl-d-glucosamine oligomers in a mouse model

Carbohydrate Polymers

Volumn 111, Issue , 2014, Pages 783-787

  Masuda, Sachie ^a   Azuma, Kazuo ^a   Kurozumi, Seiji ^a   Kiyose, Masatoshi ^a   Osaki, Tomohiro ^a   Tsuka, Takeshi ^a   Itoh, Norihiko ^a   Imagawa, Tomohiro ^a   Minami, Saburo ^a   Sato, Kimihiko ^b   Okamoto, Yoshiharu ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b Koyo Chemical Co Ltd   (Japan)

Author keywords

Chitin oligosaccharide; Chitosan oligosaccharide; Colon 26; Functional food; Mice; Tumor growth

Indexed keywords

CELL DEATH; CHITIN; GLUCOSAMINE; IMMUNE SYSTEM; OLIGOMERS; OLIGOSACCHARIDES; TUMORS;

CHITIN OLIGOSACCHARIDE; CHITOSAN OLIGOSACCHARIDE; COLON-26; FUNCTIONAL FOODS; MICE; TUMOR GROWTH;

MAMMALS;

ANTINEOPLASTIC AGENT; CYTOKINE; GAMMA INTERFERON; GLUCOSAMINE; N ACETYLGLUCOSAMINE;

ANIMAL; APOPTOSIS; BAGG ALBINO MOUSE; BLOOD; COLON; COLONIC NEOPLASMS; DISEASE MODEL; DRUG EFFECTS; FEMALE; INNATE IMMUNITY; MOUSE; ORAL DRUG ADMINISTRATION; PATHOLOGY;

ACETYLGLUCOSAMINE; ADMINISTRATION, ORAL; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; COLON; COLONIC NEOPLASMS; CYTOKINES; DISEASE MODELS, ANIMAL; FEMALE; GLUCOSAMINE; IMMUNITY, INNATE; INTERFERON-GAMMA; MICE; MICE, INBRED BALB C;

EID: 84902136814     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2014.04.102     Document Type: Article

References (23)

1. S. Akira Toll-like receptors: Lessons from knockout mice Biochem. Soc. Trans. 28 2000 551 556
2. S. Akira, K. Takeda, and T. Kaisho Toll-like receptors: Critical proteins linking innate and acquired immunity Nat. Immunol. 2 2001 675 680
3. S. Akira, S. Uematsu, and O. Takeuchi Pathogen recognition and innate immunity Cell 24 2006 783 801
4. S.A. Arancibia, C.J. Beltrán, I.M. Aguirre, P. Silva, A.L. Peralta, F. Malinarich, and M.A. Hermoso Toll-like receptors are key participants in innate immune response Biol. Res. 40 2007 97 112
5. K. Azuma, T. Ishihara, H. Nakamoto, T. Amaha, T. Osaki, T. Tsuka, T. Imagawa, S. Minami, O. Takashima, S. Ifuku, M. Morimoto, H. Saimoto, H. Kawamoto, and Y. Okamoto Effects of oral administration of fucoidan extracted from Cladosiphon okamuranus on tumor growth and survival time in a tumor-bearing mouse model Mar. Drugs 10 2012 2337 2348
6. P.N. Chen, S.C. Chu, H.L. Chiou, C.L. Chiang, S.F. Yang, and Y.S. Hsieh Cyanidin 3-glucoside and peonidin 3-glucoside inhibit tumor cell growth and induce apoptosis in vitro and suppress tumor growth in vivo Nutr. Cancer 53 2005 232 243
7. P.N. Chen, S.C. Chu, H.L. Chiou, W.H. Kuo, C.L. Chiang, and Y.S. Hsieh Mulberry anthocyanins, cyanidin 3-rutinoside and cyanidin 3-glucoside, exhibited an inhibitory effect on the migration and invasion of a human lung cancer cell line Cancer Lett. 235 2006 248 259
8. P.N. Chen, W.H. Kuo, C.L. Chiang, H.L. Chiou, Y.S. Hsieh, and S.C. Chu Black rice anthocyanins inhibit cancer cells invasion via repressions of MMPs and u-PA expression Chem. Biol. Interact. 163 2006 218 229
9. C.A. Da Silva, D. Hartl, W. Liu, C.G. Lee, and J.A. Elias TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation J. Immunol. 181 2009 4279 4286
10. K.V. Harish-Prashanth, and K.V. Tharanathan Depolymerized products of chitosan as potent inhibitors of tumor-induced angiogenesis Biochim. Biophys. Acta 1722 2005 22 29
11. R. Huang, E. Mendis, N. Rajapakse, and S.K. Kim Strong electronic charge as an important factor for anticancer activity of chitooligosaccharides (COS) Life Sci. 78 2006 2399 2408
12. E.K. Kim, J.Y. Je, S.J. Lee, Y.S. Kim, J.W. Hwang, S.H. Sung, S.H. Moon, B.T. Jeon, S.K. Kim, Y.J. Jeon, and P.J. Park Chitooligosaccharides induce apoptosis in human myeloid leukemia HL-60 cells Bioorg. Med. Chem. Lett. 22 2012 6136 6138
13. Y. Kimura, and H. Okuda Prevention by chitosan of myelotoxicity, gastrointestinal toxicity and immunocompetent organic toxicity induced by 5-fluorouracil without loss of antitumor activity in mice Cancer Sci. 90 1999 765 774
14. M. Kobayashi, T. Watanabe, S. Suzuki, and M. Suzuki Effect of N-acetylchitohexaose against Candida albicans infection of tumor-bearing mice Microbiol. Immunol. 34 1990 413 426
15. Y. Maeda, and Y. Kimura Antitumor effects of various low-molecular-weight chitosans are due to increased natural killer activity of intestinal intraepithelial lymphocytes in sarcoma 180-bearing mice J. Nutr. 134 2004 945 950
16. K.T. Shen, M.H. Chen, H.Y. Chan, J.H. Jeng, and Y.J. Wang Inhibitory effects of chitooligosaccharides on tumor growth and metastasis Food Chem. Toxicol. 47 2009 1864 1871
17. R.A.A. Muzzarelli Enhanced biochemical efficacy of oligomeric and partially depolymerized chitosans F. Columbus, Chitosan: Manufacture, Properties and Usages 2010 Nova Publ. Hauppauge, NY
18. R.A.A. Muzzarelli Human enzymatic activities related to the therapeutical administration of chitin derivatives Cell. Mol. Life Sci. 53 1997 131 140
19. K. Suzuki, T. Mikami, Y. Okawa, A. Tokoro, S. Suzuki, and M. Suzuki Antitumor effect of hexa-N-acetylchitohexaose and chitohexaose Carbohydr. Res. 151 1986 403 408
20. H. Takagi, K. Azuma, T. Tsuka, T. Imagawa, T. Osaki, and Y. Okamoto Antitumor effects of high-temperature hyperthermia on a glioma-bearing rat model according to temperature Oncol. Lett. 7 2014 1007 1010
21. A. Tokoro, N. Tatewaki, T. Mikami, S. Suzuki, and M. Suzuki Effect of NACOS-6 on lymphokine-activated killer cell (LAK) activity Biotherapy 3 1989 51 54
22. S.L. Wang, H.T. Lin, T.W. Liang, Y.J. Chen, Y.H. Yen, and S.P. Guo Reclamation of chitinous materials by bromelain for the preparation of antitumor and antifungal materials Bioresour. Technol. 99 2008 4386 4393
23. X. Zhou, D. Liu, H. Liu, Q. Yang, K. Yao, X. Wang, L. Wang, and X. Yang Effect of low molecular weight chitosans on drug permeation through mouse skin: 1. Transdermal delivery of baicalin J. Pharm. Sci. 99 2010 2991 2998