Enhanced oral bioavailability of Efavirenz by solid lipid nanoparticles: In vitro drug release and pharmacokinetics studies

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Gaur, Praveen Kumar ^a   Mishra, Shikha ^b   Bajpai, Meenakshi ^a   Mishra, Anushika ^a  

^a ITS Paramedical College (Pharmacy)   (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

EFAVIRENZ; GLYCEROL BEHENATE; GLYCEROL PALMITOSTEARATE; GLYCEROL STEARATE; POLYSORBATE 80; SOLID LIPID NANOPARTICLE; STEARIC ACID; BENZOXAZINE DERIVATIVE; CYTOCHROME P450 2B6 INDUCER; LIPID; NANOPARTICLE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG HALF LIFE; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; HUMIDITY; IN VITRO STUDY; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MOUSE; NONHUMAN; PARTICLE SIZE; PHYSICAL PARAMETERS; PREFORMULATION; SUSPENSION; TIME TO MAXIMUM PLASMA CONCENTRATION; ZETA POTENTIAL; BIOAVAILABILITY; CHEMISTRY; DRUG DELIVERY SYSTEM;

BENZOXAZINES; BIOLOGICAL AVAILABILITY; CYTOCHROME P-450 CYP2B6 INDUCERS; DRUG DELIVERY SYSTEMS; LIPIDS; NANOPARTICLES;

EID: 84902122476     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/363404     Document Type: Article

References (25)

1. Sahoo S. K., Labhasetwar V., Nanoparticles Interface: An Important Determinant in nanoparticle-Mediated Drug/Gene Delivery. Nanoparticle Technology for Drug Delivery 2006 New York, NY, USA Taylor & Francis
2. Falzarano M. S., Passarelli C., Bassi E., Biodistribution and molecular studies on orally administered nanoparticle-AON complexes encapsulated with alginate aiming at inducing dystrophin rescue in mdx mice. BioMed Research International 2013 2013 13 527418 10.1155/2013/527418
3. Gaur P., Purohit S., Mishra S., Solid lipid nanoparticles of guggul lipid as drug carrier for transdermal drug delivery. BioMed Research International 2013 2013 10 750690 10.1155/2013/750690
4. Gaur P. K., Mishra S., Aeri V., Formulation and evaluation of guggul lipid nanovesicles for transdermal delivery of aceclofenac. The Scientific World Journal 2014 2014 10 534210 10.1155/2014/534210
5. Vyas S. P., Khar R. K., Nanoparticles. Targeted and Controlled Drug Delivery-Novel Carrier Systems 2002 New Delhi, India CBS
6. Gaur P. K., Purohit S., Kumar Y., Mishra S., Bhandari A., Preparation, characterization and permeation studies of a nanovesicular system containing diclofenac for transdermal delivery. Pharmaceutical Development and Technology 2014 19 1 48 54
7. Morel S., Ugazio E., Cavalli R., Gasco M. R., Thymopentin in solid lipid nanoparticles. International Journal of Pharmaceutics 1996 132 259 261 (Pubitemid 26158724)
8. Kingsley J. D., Dou H., Morehead J., Rabinow B., Gendelman H. E., Destache C. J., Nanotechnology: a focus on nanoparticles as a drug delivery system. Journal of Neuroimmune Pharmacology 2006 1 3 340 350 2-s2.0-33747350548 10.1007/s11481-006-9032-4 (Pubitemid 44244138)
9. Attama A. A., Reichl S., Müller-Goymann C. C., Diclofenac sodium delivery to the eye: in vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct. International Journal of Pharmaceutics 2008 355 1-2 307 313 2-s2.0-41349106751 10.1016/j.ijpharm.2007.12.007
10. Bhaskar K., Anbu J., Ravichandiran V., Venkateswarlu V., Rao Y. M., Lipid nanoparticles for transdermal delivery of flurbiprofen: formulation, in vitro, ex vivo and in vivo studies. Lipids in Health and Disease 2009 8, article 6 2-s2.0-61849084577 10.1186/1476-511X-8-6
11. Chime S. A., Attama A. A., Builders P. F., Onunkwo G. C., Sustained-release diclofenac potassium-loaded solid lipid microparticle based on solidified reverse micellar solution: in vitro and in vivo evaluation. Journal of Microencapsulation 2013 30 4 335 345 10.3109/02652048.2012.726284
12. Chiappetta D. A., Hocht C., Taira C., Sosnik A., Efavirenz-loaded polymeric micelles for pediatric anti-HIV pharmacotherapy with significantly higher oral bioavailability. Nanomedicine 2010 5 1 11 23 2-s2.0-77952512814 10.2217/nnm.10.5
13. Baert L., Schueller L., Tardy Y., Macbride D., Klooster G. V., Borghys H., Clessens E., Van Den Mooter G., Van Gyseghem E., Van Remoortere P., Wigerinck P., Rosier J., Development of an implantable infusion pump for sustained anti-HIV drug administration. International Journal of Pharmaceutics 2008 355 1-2 38 44 2-s2.0-41549165542 10.1016/j.ijpharm.2008.01.029
14. Schwarz C., Mehnert W., Lucks J. S., Muller R. H., Solid lipid nanopar-ticles (SLN) for controlled drug delivery. I. Production, characteriza-tion and sterilization. Journal of Controlled Release 1994 30 83 96 (Pubitemid 24173181)
15. Gaur P. K., Purohit S., Mishra S., Development of aceclofenac nanovesicular system using biomaterial for transdermal delivery: physical characterization, ex vivo, in vivo, and anti-inflammatory studies. Journal of Biomaterials Science, Polymer Edition 2013 24 18 2126 2141
16. Gaur P. K., Purohit S., Kumar Y., Mishra S., Bhandari A., Ceramide-2 nanovesicles for effective transdermal delivery: development, characterization and pharmacokinetic evaluation. Drug Development and Industrial Pharmacy 2014 40 4 568 576 10.3109/03639045.2013.782502
17. Kwon T. K., Lim K. B., Kim J.-C., Solid lipid nanoparticles coated with silk fibroin. Journal of Industrial and Engineering Chemistry 2011 17 1 10 13 2-s2.0-79952698114 10.1016/j.jiec.2010.10.001
18. Liu D., Jiang S., Shen H., Qin S., Liu J., Zhang Q., Li R., Xu Q., Diclofenac sodium-loaded solid lipid nanoparticles prepared by emulsion/solvent evaporation method. Journal of Nanoparticle Research 2011 13 6 2375 2386 2-s2.0-80052570582 10.1007/s11051-010-9998-y
19. Nemmar A., Holme J. A., Rosas I., Schwarze P. E., Alfaro-Moreno E., Recent advances in particulate matter and nanoparticle toxicology: a review of the in vivo and in vitro studies. BioMed Research International 2013 2013 22 279371 10.1155/2013/279371.
20. Reithmeier H., Herrmann J., Göpferich A., Development and characterization of lipid microparticles as a drug carrier for somatostatin. International Journal of Pharmaceutics 2001 218 1-2 133 143 2-s2.0-0035821356 10.1016/S0378-5173(01)00620-2 (Pubitemid 32406164)
21. Ishida T., Takanashi Y., Doi H., Yamamoto I., Kiwada H., Encapsulation of an antivasospastic drug, fasudil, into liposomes, and in vitro stability of the fasudil-loaded liposomes. International Journal of Pharmaceutics 2002 232 1-2 59 67 2-s2.0-0037203663 10.1016/S0378-5173(01)00896-1 (Pubitemid 34076754)
22. Dragicevic-Curic N., Scheglmann D., Albrecht V., Fahr A., Temoporfin-loaded invasomes: development, characterization and in vitro skin penetration studies. Journal of Controlled Release 2008 127 1 59 69 2-s2.0-40649104527 10.1016/j.jconrel.2007.12.013
23. Jukanti R., Sheela S., Bandari S., Veerareddy P. R., Enhanced bioavailability of exemestane via proliposomes based transdermal delivery. Journal of Pharmaceutical Sciences 2011 100 8 3208 3222 2-s2.0-79958777017 10.1002/jps.22542
24. Patel G. V., Patel V. B., Pathak A., Rajput S. J., Nanosuspension of efavirenz for improved oral bioavailability: formulation optimization, in vitro, in situ and in vivo evaluation. Drug Development and Industrial Pharmacy 2014 40 1 80 91
25. Helgason T., Awad T. S., Kristbergsson K., McClements D. J., Weiss J., Effect of surfactant surface coverage on formation of solid lipid nanoparticles (SLN). Journal of Colloid and Interface Science 2009 334 1 75 81 2-s2.0-67349126164 10.1016/j.jcis.2009.03.012