Noninvasive measurement of aristolochic acid-DNA adducts in urine samples from aristolochic acid-treated rats by liquid chromatography coupled tandem mass spectrometry: Evidence for DNA repair by nucleotide-excision repair mechanisms

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 766-767, Issue , 2014, Pages 1-6

  Leung, Elvis M K ^a   Chan, Wan ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

Author keywords

Aristolochic acids; Balkan endemic nephropathy; DNA adducts; LC MS MS; Nucleotide excision repair; Urine

Indexed keywords

7 (DEOXYADENOSINE N6 YL) ARISTOLACTAM I; 7 (DEOXYGUANOSINE N2 YL) ARISTOLACTAM I; 7 (DEOXYGUANOSINE N2 YL) ARISTOLACTAM II; 7 (DEOXYGUANOSINE N6 YL) ARISTOLACTAM II; ARISTOLOCHIC ACID; UNCLASSIFIED DRUG; ARISTOLOCHIC ACID I; CARCINOGEN; DNA ADDUCT;

ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CHROMATOGRAPHY; CONTROLLED STUDY; DNA ADDUCT; ENRICHMENT CULTURE; EXCISION REPAIR; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY COUPLED TANDEM MASS SPECTROMETRY; MALE; MEASUREMENT ACCURACY; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SOLID PHASE EXTRACTION; STANDARD; TANDEM MASS SPECTROMETRY; URINALYSIS; ANIMAL; DNA REPAIR; DRUG EFFECTS; LIMIT OF DETECTION; PROCEDURES; SENSITIVITY AND SPECIFICITY; SPRAGUE DAWLEY RAT; URINE;

ANIMALS; ARISTOLOCHIC ACIDS; CARCINOGENS; CHROMATOGRAPHY, LIQUID; DNA ADDUCTS; DNA REPAIR; LIMIT OF DETECTION; MALE; RATS; RATS, SPRAGUE-DAWLEY; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; URINALYSIS;

EID: 84902109428     PISSN: 00275107     EISSN: 09218262     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2014.05.004     Document Type: Article

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