Intracellular amyloid beta alters the tight junction of retinal pigment epithelium in 5XFAD mice

Neurobiology of Aging

Volumn 35, Issue 9, 2014, Pages 2013-2020

  Park, Sung Wook ^a,b   Kim, Jin Hyoung ^a   Mook Jung, Inhee ^b   Kim, Kyu Won ^c   Park, Woo Jin ^d   Park, Kyu Hyung ^b,e   Kim, Jeong Hun ^a,b  

^a Seoul National University Hospital   (South Korea)

^b Seoul National University   (South Korea)

^c Seoul National University   (South Korea)

^d Gwangju Institute of Science and Technology (GIST)   (South Korea)

^e Seoul National University Bundang Hospital   (South Korea)

Author keywords

Age related macular degeneration; Aging; Alzheimer's disease; A ; Outer blood retinal barrier; Retina; Retinal pigment epithelium; Tight junction; Transgenic mice

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; CELL PROTEIN; OCCLUDIN; UNCLASSIFIED DRUG; ZONULAR OCCLUDENS 1 PROTEIN; AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT; PROTEIN ZO1;

5XFAD MOUSE; ALZHEIMER DISEASE; ANIMAL TISSUE; ARPE 19 CELL LINE; ARTICLE; BLOOD RETINA BARRIER; CELL LINE; DISEASE MODEL; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; PROTEIN TRANSPORT; TIGHT JUNCTION; ANIMAL; CELL CULTURE; CYTOLOGY; MACULAR DEGENERATION; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

AMYLOID BETA-PEPTIDES; ANIMALS; BLOOD-RETINAL BARRIER; CELLS, CULTURED; DISEASE MODELS, ANIMAL; MACULAR DEGENERATION; MICE, TRANSGENIC; OCCLUDIN; PEPTIDE FRAGMENTS; RETINAL PIGMENT EPITHELIUM; TIGHT JUNCTIONS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84902077336     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2014.03.008     Document Type: Article

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