Carrier-Mediated Transport Through Biomembranes

Transport in Biological Media

Volumn , Issue , 2013, Pages 181-212

  Pradhan, Ranjan K ^a   Vinnakota, Kalyan C ^a   Beard, Daniel A ^a   Dash, Ranjan K ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Biomembranes; Carriers and pores; Free energy barrier theory; Kinetic analysis; Rapid equilibrium and quasi steady state models

Indexed keywords

EID: 84902069997     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-415824-5.00005-9     Document Type: Chapter

References (46)

1. A.B. Harvey Lodish, Chris A. Kaiser, Monty Krieger, Matthew P. Scott, Molecular Cell Biology, sixth ed., W.H. Freeman, 2007.
2. Stein W. The Movement of Molecules Across Cell Membranes 1967, Academic Press, New York.
3. Mueckler M., Caruso C., Baldwin S.A., Panico M., Blench I., Morris H.R., Allard W.J., Lienhard G.E., Lodish H.F. Sequence and structure of a human glucose transporter. Science 1985, 229:941-945.
4. Poole R.C., Halestrap A.P. Transport of lactate and other monocarboxylates across mammalian plasma membranes. The American Journal of Physiology 1993, 264:C761-C782.
5. Mullins L.J. An electrogenic saga: consequences of sodium-calcium exchange in cardiac muscle. Society General of Physiologists Series 1984, 38:161-179.
6. Stein W.D. Channels, Carriers, and Pumps: An Introduction to Membrane Transport 1990, Academic Press.
7. Stein W.D. Transport and Diffusion Across Cell Membranes 1986, Academic Press, San Diego CA, USA.
8. Lauger P. Ion transport through pores: a rate-theory analysis. Biochimica Biophysica Acta 1973, 311:423-441.
9. Lauger P., Neumcke B. Theoretical analysis of ion conductance in lipid bilayer membranes. Membranes 1973, 2:1-59.
10. Keener J.P., Sneyd J. Mathematical Physiology 1998, Springer, New York.
11. Beard D.A. Biosimulation: Simulation of Living Systems 2012, Cambridge University Press, Cambridge, UK.
12. Lieb W.R. A Kinetic Approach to Transport Studies. Red Cell Membranes a Methodological Approach 1982, Academic Press, London.
13. Rosenberg T., Wilbrandt W. Uphill transport induced by counterflow. The Journal of General Physiology 1957, 41:289-296.
14. Bernardi P. Mitochondrial transport of cations: channels, exchangers, and permeability transition. Physiological Review 1999, 79:1127-1155.
15. Gunter T.E., Pfeiffer D.R. Mechanisms by which mitochondria transport calcium. American Journal of Physiology 1990, 258:C755-C786.
16. Chance B. The energy-linked reaction of calcium with mitochondria. The Journal of Biological Chemistry 1965, 240:2729-2748.
17. Rottenberg H. The measurement of membrane potential and delta pH in cells, organelles, and vesicles. Methods in enzymology 1979, 55:547-569.
18. Bragadin M., Pozzan T., Azzone G.F. Kinetics of Ca2+ carrier in rat liver mitochondria. Biochemistry 1979, 18:5972-5978.
19. Crompton M., Sigel E., Salzmann M., Carafoli E. A kinetic study of the energy-linked influx of Ca2+ into heart mitochondria. European Journal of Biochemistry 1976, 69:429-434.
20. Scarpa A., Graziotti P. Mechanisms for intracellular calcium regulation in heart. I. Stopped-flow measurements of Ca2+ uptake by cardiac mitochondria. Journal of General Physiology 1973, 62:756-772.
21. Vinogradov A., Scarpa A. The initial velocities of calcium uptake by rat liver mitochondria. The Journal of Biological Chemistry 1973, 248:5527-5531.
22. Wingrove D.E., Amatruda J.M., Gunter T.E. Glucagon effects on the membrane potential and calcium uptake rate of rat liver mitochondria. Journal of Biological Chemistry 1984, 259:9390-9394.
23. Gunter T.E., Wingrove D.E., Banerjee S., Gunter K.K. Mechanisms of mitochondrial calcium transport. Advances in Experimental Medicine and Biology 1988, 232:1-14.
24. Bygrave F.L., Reed K.C., Spencer T. Cooperative interactions in energy-dependent accumulation of Ca2+ by isolated rat liver mitochondria. Nature New Biology 1971, 230:89.
25. Pradhan R.K., Qi F., Beard D.A., Dash R.K. Characterization of membrane potential dependency of mitochondrial Ca2+ uptake by an improved biophysical model of mitochondrial Ca2+ uniporter. PLoS One 2010, 5:e13278.
26. Kirichok Y., Krapivinsky G., Clapham D.E. The mitochondrial calcium uniporter is a highly selective ion channel. Nature 2004, 427:360-364.
27. Baughman J.M., Perocchi F., Girgis H.S., Plovanich M., Belcher-Timme C.A., Sancak Y., Bao X.R., Strittmatter L., Goldberger O., Bogorad R.L., Koteliansky V., Mootha V.K. Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter. Nature 2011, 476:341-345.
28. De Stefani D., Raffaello A., Teardo E., Szabo I., Rizzuto R. A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter. Nature 2011, 476:336-340.
29. Dash R.K., Beard D.A. Analysis of cardiac mitochondrial Na+/Ca2+ exchanger kinetics with a biophysical model of mitochondrial Ca2+ handling suggests a 3:1 stoichiometry. Journal of Physiology 2008, 586:3267-3285.
30. Dash R.K., Qi F., Beard D.A. A biophysically-based mathematical model for the kinetics of mitochondrial calcium uniporter. Biophysical Journal 2009, 96:1318-1332.
31. Pradhan R.K., Qi F., Beard D.A., Dash R.K. Characterization of Mg2+ inhibition of mitochondrial Ca2+ uptake by a mechanistic model of mitochondrial Ca2+ uniporter. Biophysical Journal 2011, 101:2071-2081.
32. Magnus G., Keizer J. Minimal model of beta-cell mitochondrial Ca2+ handling. American Journal of Physiology 1997, 273:C717-C733.
33. Cortassa S., Aon M.A., Marban E., Winslow R.L., O'Rourke B. An integrated model of cardiac mitochondrial energy metabolism and calcium dynamics. Biophysical Journal 2003, 84:2734-2755.
34. Nguyen M.H., Jafri M.S. Mitochondrial calcium signaling and energy metabolism. Annals of the New York Academy of Sciences 2005, 1047:127-137.
35. Nguyen M.H., Dudycha S.J., Jafri M.S. The Effects of Ca2+ on cardiac mitochondrial energy production is modulated by Na+ and H+ dynamics. American Journal of Physiology and Cell Physiology 2007, 292:2004-2020.
36. Romani A., Scarpa A. Hormonal control of Mg2+ transport in the heart. Nature 1990, 346:841-844.
37. Szanda G., Rajki A., Gallego-Sandin S., Garcia-Sancho J., Spat A. Effect of cytosolic Mg2+ on mitochondrial Ca2+ signaling. Pflugers Archiv 2009, 457:941-954.
38. Klingenberg M. The ADP-ATP translocation in mitochondria, a membrane potential controlled transport. The Journal of Membrane Biology 1980, 56:97-105.
39. Metelkin E., Goryanin I., Demin O. Mathematical modeling of mitochondrial adenine nucleotide translocase. Biophysical Journal 2006, 90:423-432.
40. Baysal K., Jung D.W., Gunter K.K., Gunter T.E., Brierley G.P. Na+-dependent Ca2+ efflux mechanism of heart mitochondria is not a passive Ca2+/2Na+ exchanger. American Journal of Physiology 1994, 266:C800-C808.
41. Seifter J.L., Aronson P.S. Properties and physiologic roles of the plasma membrane sodium-hydrogen exchanger. The Journal of Clinical Investigation 1986, 78:859-864.
42. Kapus A., Ligeti E., Fonyo A. Na+/H+ exchange in mitochondria as monitored by BCECF fluorescence. FEBS Letters 1989, 251:49-52.
43. Pradhan R.K., Beard D.A., Dash R.K. A biophysically based mathematical model for the kinetics of mitochondrial Na+-Ca2+ antiporter. Biophysical Journal 2010, 98:218-230.
44. Stein W.D. The cotransport systems. Current Opinion in Cell Biology 1989, 1:739-745.
45. Stein W.D. Kinetics of transport: analyzing, testing, and characterizing models using kinetic approaches. Methods in Enzymology 1989, 171:23-62.
46. Vinnakota K.C., Beard D.A. Kinetic analysis and design of experiments to identify the catalytic mechanism of the monocarboxylate transporter isoforms 4 and 1. Biophysical Journal 2011, 100:369-380.