Metadata standard and data exchange specifications to describe, model, and integrate complex and diverse high-throughput screening data from the library of integrated network-based cellular signatures (LINCS)

Journal of Biomolecular Screening

Volumn 19, Issue 5, 2014, Pages 803-816

  Vempati, Uma D ^a   Chung, Caty ^a   Mader, Chris ^a   Koleti, Amar ^a   Datar, Nakul ^a   Vidović, Dušica ^a   Wrobel, David ^b   Erickson, Sean ^b   Muhlich, Jeremy L ^b   Berriz, Gabriel ^b   Benes, Cyril H ^c   Subramanian, Aravind ^d   Pillai, Ajay ^e   Shamu, Caroline E ^b   Schürer, Stephan C ^a,f  

^a UNIVERSITY OF MIAMI   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^e NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^f UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

Author keywords

Cell based assays; Data standards; Database and data management; Enzyme assays or enzyme kinetics; Gene expression; Metadata

Indexed keywords

ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY ASSAY; CONTROLLED VOCABULARY; DATA ANALYSIS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HIGH THROUGHPUT SCREENING; HUMAN; INFORMATION PROCESSING; INFORMATION SYSTEM; INTRACELLULAR SIGNALING; LIBRARY OF INTEGRATED NETWORK BASED CELLULAR SIGNATURE; MASS SPECTROMETRY; MEDICAL SUBJECT HEADINGS; METADATA SPECIFICATION; MOLECULAR LIBRARY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; RNA INTERFERENCE; SIMPLE ANNOTATION FORMAT; SYSTEMS BIOLOGY; BIOLOGY; CELL LINE; CHEMISTRY; FEMALE; GENE EXPRESSION REGULATION; GENE LIBRARY; INTERNET; KINETICS; MALE; METABOLISM; METADATA; MUTATION; NATIONAL HEALTH ORGANIZATION; OVARY TUMOR; PROCEDURES; UNITED STATES;

ANTIBODY; MOLECULAR LIBRARY; PROTEIN; SMALL INTERFERING RNA;

ANTIBODIES; CELL LINE; COMPUTATIONAL BIOLOGY; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE LIBRARY; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTERNET; KINETICS; MALE; METADATA; MUTATION; NATIONAL INSTITUTES OF HEALTH (U.S.); OVARIAN NEOPLASMS; PROTEINS; RNA, SMALL INTERFERING; SMALL MOLECULE LIBRARIES; UNITED STATES;

EID: 84902007425     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057114522514     Document Type: Article

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