Nano-volume well array chip for large-scale propagation and high-resolution analysis of individual cancer stem cells

Journal of Nanomedicine and Nanotechnology

Volumn 5, Issue 2, 2014, Pages

  Clausell Tormos, Jenifer ^a   Azevedo, Maria M ^a   Miranda Lorenzo, Irene ^a   Vieira, Catarina R ^a   Sanchez Ripoll, Yolanda ^a   Megias, Diego ^a   Heeschen, Christopher ^a,b  

^a Structural Biology and Biocomputing Programme   (Spain)

^b QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Cancer stem cells; Niche; Pancreatic cancer

Indexed keywords

FLUORESCENT DYE;

ARTICLE; CANCER CELL CULTURE; CANCER STEM CELL; CELL DIVISION; CELL ISOLATION; CLONAL VARIATION; FLUORESCENCE ACTIVATED CELL SORTING; HIGH RESOLUTION ANALYSIS; HUMAN; HUMAN CELL; IMAGE ANALYSIS; LARGE SCALE PRODUCTION; NANOARRAY; NANOCHIP; NANOFABRICATION; PANCREAS CANCER; PHENOTYPE; PRIMARY CELL; SINGLE CELL ANALYSIS; TUMOR SEEDING;

EID: 84901989811     PISSN: None     EISSN: 21577439     Source Type: Journal    
DOI: 10.4172/2157-7439.1000191     Document Type: Article

References (30)

1. Altschuler SJ, Wu LF (2010) Cellular heterogeneity: do differences make a difference? Cell 141: 559-563
2. Dykstra B, Olthof S, Schreuder J, Ritsema M, de Haan G (2011) Clonal analysis reveals multiple functional defects of aged murine hematopoietic stem cells. J Exp Med 208: 2691-2703
3. Dalerba P, Kalisky T, Sahoo D, Rajendran PS, Rothenberg ME, et al. (2011) Single-cell dissection of transcriptional heterogeneity in human colon tumors. Nat Biotechnol 29: 1120-1127
4. Mukhopadhyay P, Farrell T, Sharma G, McGuire TR, O'Kane B, et al. (2013) Heterogeneity of functional properties of clone 66 murine breast cancer cells expressing various stem cell phenotypes. PLoS One 8: e78725
5. Susman S, Tomuleasa C, Soritau O, Mihu C, Rus-Ciuca D, et al. (2012) The colorectal cancer stem-like cell hypothesis: a pathologist's point of view. J BUON 17: 230-236
6. Ahmed AU, Auffinger B, Lesniak MS (2013) Understanding glioma stem cells: rationale, clinical relevance and therapeutic strategies. Expert Rev Neurother 13: 545-555
7. Yamashita T, Wang XW (2013) Cancer stem cells in the development of liver cancer. J Clin Invest 123: 1911-1918
8. Hermann PC, Bhaskar S, Cioffi M, Heeschen C (2010) Cancer stem cells in solid tumors. Semin Cancer Biol 20: 77-84
9. Barteneva NS, Ketman K, Fasler-Kan E, Potashnikova D, Vorobjev IA (2013) Cell sorting in cancer research--diminishing degree of cell heterogeneity. Biochim Biophys Acta 1836: 105-122
10. Shaw FL, Harrison H, Spence K, Ablett MP, Simões BM, et al. (2012) A detailed mammosphere assay protocol for the quantification of breast stem cell activity. J Mammary Gland Biol Neoplasia 17: 111-117
11. Hermann PC, Huber SL, Herrler T, Aicher A, Ellwart JW, et al. (2007) Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer. Cell Stem Cell 1: 313-323
12. Liu J, Ruan B, You N, Huang Q, Liu W, et al. (2013) Downregulation of miR- 200a induces EMT phenotypes and CSC-like signatures through targeting the β-catenin pathway in hepatic oval cells. PLoS One 8: e79409
13. Hirschhaeuser F, Menne H, Dittfeld C, West J, Mueller-Klieser W, et al. (2010) Multicellular tumor spheroids: an underestimated tool is catching up again. J Biotechnol 148: 3-15
14. McDonald JC, Duffy DC, Anderson JR, Chiu DT, Wu H, et al. (2000) Fabrication of microfluidic systems in poly(dimethylsiloxane). Electrophoresis 21: 27-40
15. Suh KY, Seong J, Khademhosseini A, Laibinis PE, Langer R (2004) A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning. Biomaterials 25: 557-563
16. Revzin A, Rajagopalan P, Tilles AW, Berthiaume F, Yarmush ML, et al. (2004) Designing a hepatocellular microenvironment with protein microarraying and poly(ethylene glycol) photolithography. Langmuir 20: 2999-3005
17. Deutsch A, Zurgil N, Hurevich I, Shafran Y, Afrimzon E, et al. (2006) Microplate cell-retaining methodology for high-content analysis of individual non-adherent unanchored cells in a population. Biomed Microdevices 8: 361-374
18. Chin VI, Taupin P, Sanga S, Scheel J, Gage FH, et al. (2004) Microfabricated platform for studying stem cell fates. Biotechnol Bioeng 88: 399-415
19. Gilbert PM, Havenstrite KL, Magnusson KE, Sacco A, Leonardi NA, et al. (2010) Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture. Science 329: 1078-1081
20. Dykstra B, Ramunas J, Kent D, McCaffrey L, Szumsky E, et al. (2006) Highresolution video monitoring of hematopoietic stem cells cultured in single-cell arrays identifies new features of self-renewal. Proc Natl Acad Sci U S A 103: 8185-8190
21. Lindström S, Larsson R, Svahn HA (2008) Towards high-throughput single cell/ clone cultivation and analysis. Electrophoresis 29: 1219-1227
22. Qin D, Xia Y, Whitesides GM (2010) Soft lithography for micro- and nanoscale patterning. Nat Protoc 5: 491-502
23. Jones MC, Kobie JJ, Delouise LA (2013) Characterization of cell seeding and specific capture of B cells in microbubble well arrays. Biomed Microdevices 15: 453-463
24. Li Y, Zhang J, Liu W, Li D, Fang L, et al. (2013) Hierarchical polymer brush nanoarrays: a versatile way to prepare multiscale patterns of proteins. ACS Appl Mater Interfaces 5: 2126-2132
25. Liu W, Li Y, Wang T, Li D, Fang L, et al. (2013) Elliptical polymer brush ring array mediated protein patterning and cell adhesion on patterned protein surfaces. ACS Appl Mater Interfaces 5: 12587-12593
26. van Herwaarden AE, Wagenaar E, Merino G, Jonker JW, Rosing H, et al. (2007) Multidrug transporter ABCG2/breast cancer resistance protein secretes riboflavin (vitamin B2) into milk. Mol Cell Biol 27: 1247-1253
27. Willasch A, Eing S, Weber G, Kuci S, Schneider G, et al. (2010) Enrichment of cell subpopulations applying automated MACS technique: purity, recovery and applicability for PCR-based chimerism analysis. Bone Marrow Transplant 45: 181-189
28. Williams SC (2013) Circulating tumor cells. Proc Natl Acad Sci U S A 110: 4861
29. Lonardo E, Hermann PC, Mueller MT, Huber S, Balic A, et al. (2011) Nodal/ Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy. Cell Stem Cell 9: 433-446
30. Lonardo E, Frias-Aldeguer J, Hermann PC, Heeschen C (2012) Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness. Cell Cycle 11: 1282-1290.