Genetics: ACVR1 mutations-A key piece in paediatric diffuse glioma

Nature Reviews Clinical Oncology

Volumn 11, Issue 6, 2014, Pages 300-

  Villanueva, M Teresa ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVIN RECEPTOR 1; BONE MORPHOGENETIC PROTEIN; INHIBITOR OF DIFFERENTIATION PROTEIN; SMAD PROTEIN;

ACVR1 GENE; ASTROCYTOMA; CHILDHOOD CANCER; GENE MUTATION; GLIOBLASTOMA; GLIOMA; HUMAN; NOTE; PONTINE GLIOMA; PRIORITY JOURNAL; SOMATIC MUTATION;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; ASTROCYTOMA; BRAIN NEOPLASMS; BRAIN STEM NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME, HUMAN; GLIOMA; HUMANS; MUTATION; MUTATION, MISSENSE; SIGNAL TRANSDUCTION;

EID: 84901981614     PISSN: 17594774     EISSN: 17594782     Source Type: Journal    
DOI: 10.1038/nrclinonc.2014.74     Document Type: Note

References (4)

1. Wu, G. et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat. Genet. 46, 444-450 (2014) |
2. Buczkowicz, P. et al. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nat. Genet. 46, 451-456 (2014) |
3. Taylor, K. R. et al. Recurrent activating ACVR1 mutations in diffuse intrinsic pontine glioma. Nat. Genet. 46, 457-461 (2014) |
4. Fontebasso, A. M. et al. Recurrent somatic mutations in ACVR1 in pediatric midline high-grade astrocytoma. Nat. Genet. 46, 462-466 (2014)