A mouse Col4a4 mutation causing Alport glomerulosclerosis with abnormal collagen α3α4α5(IV) trimers

Kidney International

Volumn 85, Issue 6, 2014, Pages 1461-1468

  Korstanje, Ron ^a   Caputo, Christina R ^a   Doty, Rosalinda A ^a   Cook, Susan A ^a   Bronson, Roderick T ^a   Davisson, Muriel T ^a   Miner, Jeffrey H ^b  

^a JACKSON LABORATORY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

albuminuria; Alport syndrome; extracellular matrix; genetic renal disease; glomerular disease

Indexed keywords

COLLAGEN ALPHA3ALPHA4ALPHA5 TRIMER; COLLAGEN TYPE 4; GENOMIC DNA; MESSENGER RNA; UNCLASSIFIED DRUG; AUTOANTIGEN; COL4A5 PROTEIN, MOUSE; TYPE IV COLLAGEN ALPHA3 CHAIN;

ALBUMINURIA; ALPORT SYNDROME; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; COL4A4 GENE; CONTROLLED STUDY; DNA SEQUENCE; ELECTRON MICROSCOPY; EXON SKIPPING; FEMALE; GENE; GENE MAPPING; GENE MUTATION; GLOMERULUS BASEMENT MEMBRANE; IMMUNOHISTOCHEMISTRY; INTRON; KIDNEY INJURY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; URINALYSIS; 129 MOUSE; ANIMAL; DBA MOUSE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MUTATION; NEPHRITIS; PATHOLOGY; PHENOTYPE; PROTEIN MULTIMERIZATION; TIME FACTOR;

ALBUMINURIA; ANIMALS; AUTOANTIGENS; COLLAGEN TYPE IV; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; GLOMERULAR BASEMENT MEMBRANE; MALE; MICE, 129 STRAIN; MICE, INBRED DBA; MUTATION; NEPHRITIS, HEREDITARY; PHENOTYPE; PROTEIN MULTIMERIZATION; RNA, MESSENGER; TIME FACTORS;

EID: 84901917987     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2013.493     Document Type: Article

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