A biochemical and physicochemical comparison of two recombinant enzymes used for enzyme replacement therapies of hunter syndrome

Glycoconjugate Journal

Volumn 31, Issue 4, 2014, Pages 309-315

  Chung, Yo Kyung ^a,b   Sohn, Young Bae ^c   Sohn, Jong Mun ^b   Lee, Jieun ^d   Chang, Mi Sun ^d   Kwun, Younghee ^d   Kim, Chi Hwa ^e   Lee, Jin Young ^f   Yook, Yeon Joo ^f   Ko, Ah Ra ^f   Jin, Dong Kyu ^d  

^a Ajou University   (South Korea)

^b Green Cross Company   (South Korea)

^c Ajou University School of Medicine   (South Korea)

^d Sungkyunkwan University School of Medicine   (South Korea)

^e Mogam Biotechnology Research Institute   (South Korea)

^f Samsung Medical Center   (South Korea)

Author keywords

Enzyme replacement therapy; Formylglycine; Hunter syndrome; Iduronate 2 sulfatase; Mannose 6 phosphate; MPS II

Indexed keywords

FORMYLGLYCINE; GENERIC DRUG; GLYCINE; HUNTERASE; IDURONATE 2 SULFATASE; MANNOSE 6 PHOSPHATE; SIALIC ACID; UNCLASSIFIED DRUG; ALANINE; C(ALPHA)-FORMYLGLYCINE; HYBRID PROTEIN; MANNOSE PHOSPHATE; MANNOSE-6-PHOSPHATE; N ACETYLNEURAMINIC ACID;

ARTICLE; BIOCHEMISTRY; CARBOHYDRATE ANALYSIS; CELL TRANSPORT; CELLULAR DISTRIBUTION; CLINICAL EFFECTIVENESS; CLINICAL EVALUATION; COMPARATIVE STUDY; ENZYME ACTIVITY; ENZYME REPLACEMENT; ENZYME STABILITY; HUMAN; HUMAN CELL; HUNTER SYNDROME; IMMUNOGENICITY; IN VITRO STUDY; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN FUNCTION; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; DRUG EFFECTS; FIBROBLAST; HAMSTER; MUCOPOLYSACCHARIDOSIS II;

ALANINE; ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; ENZYME REPLACEMENT THERAPY; FIBROBLASTS; GLYCINE; HUMANS; IDURONATE SULFATASE; MANNOSEPHOSPHATES; MUCOPOLYSACCHARIDOSIS II; N-ACETYLNEURAMINIC ACID; RECOMBINANT FUSION PROTEINS;

EID: 84901857363     PISSN: 02820080     EISSN: 15734986     Source Type: Journal    
DOI: 10.1007/s10719-014-9523-0     Document Type: Article

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