Punicalagin and ellagic acid demonstrate antimutagenic activity and inhibition of benzo[a]pyrene induced DNA adducts

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Zahin, Maryam ^a,b   Ahmad, Iqbal ^a   Gupta, Ramesh C ^b,c   Aqil, Farrukh ^b,c  

^a ALIGARH MUSLIM UNIVERSITY   (India)

^b UNIVERSITY OF LOUISVILLE   (United States)

^c University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINOFLUORINE; ANTIMUTAGENIC AGENT; BENZO[A]PYRENE; ELLAGIC ACID; ELLAGITANNIN; FLUORINE; METHYL METHANSULFONATE; PUNICALAGIN; SODIUM AZIDE; SULFONIC ACID DERIVATIVE; UNCLASSIFIED DRUG; ANTIOXIDANT; DNA ADDUCT; PLANT EXTRACT; TANNIN;

AMES TEST; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL; DNA ADDUCT; DNA DAMAGE; DRUG EFFECT; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; LIVER MICROSOME; LUNG CANCER; MUTAGENIC ACTIVITY; MUTAGENICITY; NONHUMAN; ANIMAL; CHEMISTRY; DRUG EFFECTS; LYTHRACEAE; MUTAGENESIS; RAT; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM;

ANIMALS; ANTIOXIDANTS; BENZO(A)PYRENE; DNA ADDUCTS; DNA DAMAGE; ELLAGIC ACID; HUMANS; HYDROLYZABLE TANNINS; MUTAGENESIS; PLANT EXTRACTS; PUNICACEAE; RATS; SALMONELLA TYPHIMURIUM;

EID: 84901817504     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/467465     Document Type: Article

References (37)

1. Gutteridge J. M. C., Invited review. Free radicals in disease processes: a compilation of cause and consequence. Free Radical Research Communications 1993 19 3 141 158 2-s2.0-0027765905 (Pubitemid 23330337)
2. Valko M., Leibfritz D., Moncol J., Cronin M. T. D., Mazur M., Telser J., Free radicals and antioxidants in normal physiological functions and human disease. International Journal of Biochemistry and Cell Biology 2007 39 1 44 84 2-s2.0-33749986298 10.1016/j.biocel.2006.07.001 (Pubitemid 44566469)
3. Govindarajan R., Vijayakumar M., Pushpangadan P., Antioxidant approach to disease management and the role of "Rasayana" herbs of Ayurveda. Journal of Ethnopharmacology 2005 99 2 165 178 2-s2.0-19444381010 10.1016/j.jep.2005.02.035 (Pubitemid 40724391)
4. El-Sayed W. M., Hussin W. A., Antimutagenic and antioxidant activity of novel 4-substituted phenyl-2, 2′-bichalcophenes and aza-analogs. Journal of Drug Design, Development and Therapy 2013 7 73 81
5. Cardador-Martínez A., Albores A., Bah M., Calderón-Salinas V., Castaño-Tostado E., Guevara-González R., Shimada-Miyasaka A., Loarca-Piña G., Relationship among antimutagenic, antioxidant and enzymatic activities of methanolic extract from common beans (Phaseolus vulgaris L). Plant Foods for Human Nutrition 2006 61 4 161 168 2-s2.0-33845464801 10.1007/s11130-006-0026-4 (Pubitemid 44892526)
6. Hemminki K., DNA adducts, mutations and cancer. Carcinogenesis 1993 14 10 2007 2012 2-s2.0-0027382208 (Pubitemid 23311424)
7. Hemminki K., Koskinen M., Rajaniemi H., Zhao C., DNA adducts, mutations, and cancer 2000. Regulatory Toxicology and Pharmacology 2000 32 3 264 275 2-s2.0-0034471653 10.1006/rtph.2000.1431 (Pubitemid 32163699)
8. Phillips D. H., DNA adducts in human tissues: biomarkers of exposure to carcinogens in tobacco smoke. Environmental Health Perspectives 1996 104 supplement 3 453 458 2-s2.0-0029886862 (Pubitemid 26196385)
9. Loeb L. A., Harris C. C., Advances in chemical carcinogenesis: a historical review and prospective. Cancer Research 2008 68 17 6863 6872 2-s2.0-52049125943 10.1158/0008-5472.CAN-08-2852
10. Godschalk R. W. L., van Schooten F.-J., Bartsch H., A critical evaluation of DNA adducts as biological markers for human exposure to polycyclic aromatic compounds. Journal of Biochemistry and Molecular Biology 2003 36 1 1 11 2-s2.0-0037530145 (Pubitemid 36836250)
11. Ferguson L. R., Antimutagens as cancer chemopreventive agents in the diet. Mutation Research: Fundamental and Molecular Mechanisms of Mutagenesis 1994 307 1 395 410 2-s2.0-0028242181 10.1016/0027-5107(94)90313-1 (Pubitemid 24155070)
12. Green M., Thomas R., Gued L., Sadrud-Din S., Inhibition of DES-induced DNA adducts by diallyl sulfide: implications in liver cancer prevention. Oncology Reports 2003 10 3 767 771 2-s2.0-0642283859
13. Aqil F., Zahin M., Ahmad I., Antimutagenic activity of methanolic extracts of four ayurvedic medicinal plants. Indian Journal of Experimental Biology 2008 46 9 668 672 2-s2.0-67549095523
14. Khader M., Bresgen N., Eckl P. M., Antimutagenic effects of ethanolic extracts from selected Palestinian medicinal plants. Journal of Ethnopharmacology 2010 127 2 319 324 2-s2.0-73749083639 10.1016/j.jep.2009.11. 001
15. Zahin M., Aqil F., Ahmad I., Broad spectrum antimutagenic activity of antioxidant active fraction of Punica granatum L. peel extracts. Mutation Research: Genetic Toxicology and Environmental Mutagenesis 2010 703 2 99 107 2-s2.0-78549278382 10.1016/j.mrgentox.2010.08.001
16. Aqil F., Ahmad I., Antibacterial properties of traditionally used Indian medicinal plants. Methods and Findings in Experimental and Clinical Pharmacology 2007 29 2 79 92 2-s2.0-34249016692 10.1358/mf.2007.29.2.1075347 (Pubitemid 46797626)
17. Seeram N. P., Adams L. S., Henning S. M., Niu Y., Zhang Y., Nair M. G., Heber D., In vitro antiproliferative, apoptotic and antioxidant activities of punicalagin, ellagic acid and a total pomegranate tannin extract are enhanced in combination with other polyphenols as found in pomegranate juice. Journal of Nutritional Biochemistry 2005 16 6 360 367 2-s2.0-20144381777 10.1016/j.jnutbio.2005.01.006 (Pubitemid 40776045)
18. Seeram N., Lee R., Hardy M., Heber D., Rapid large scale purification of ellagitannins from pomegranate husk, a by-product of the commercial juice industry. Separation and Purification Technology 2005 41 1 49 55 2-s2.0-7444220592 10.1016/j.seppur.2004.04.003
19. Aqil F., Munagala R., Vadhanam M. V., Kausar H., Jeyabalan J., Schultz D. J., Gupta R. C., Anti-proliferative activity and protection against oxidative DNA damage by punicalagin isolated from pomegranate husk. Food Research International 2012 49 1 345 353 10.1016/j.foodres.2012.07.059
20. Landete J. M., Ellagitannins, ellagic acid and their derived metabolites: a review about source, metabolism, functions and health. Food Research International 2011 44 5 1150 1160 2-s2.0-79957598613 10.1016/j.foodres.2011.04. 027
21. Lin C.-C., Hsu Y.-F., Lin T.-C., Effects of punicalagin and punicalin on carrageenan-induced inflammation in rats. American Journal of Chinese Medicine 1999 27 3-4 371 376 2-s2.0-0033258057
22. Lin C.-C., Hsu Y.-F., Lin T.-C., Hsu H.-Y., Antioxidant and hepatoprotective effects of punicalagin and punicalin on acetaminophen-induced liver damage in rats. Phytotherapy Research 2001 15 3 206 212 2-s2.0-0035020672 10.1002/ptr.816 (Pubitemid 32458627)
23. Chen P.-S., Li J.-H., Liu T.-Y., Lin T.-C., Folk medicine Terminalia catappa and its major tannin component, punicalagin, are effective against bleomycin-induced genotoxicity in Chinese hamster ovary cells. Cancer Letters 2000 152 2 115 122 2-s2.0-0034193611 10.1016/S0304-3835(99)00395-X (Pubitemid 30201491)
24. Heber D., Multitargeted therapy of cancer by ellagitannins. Cancer Letters 2008 269 2 262 268 2-s2.0-51349096457 10.1016/j.canlet.2008.03.043
25. Maron D. M., Ames B. N., Revised methods for the Salmonella mutagenicity test. Mutation Research 1983 113 3-4 173 215 2-s2.0-0020533372 (Pubitemid 13120319)
26. Zahin M., Ahmad I., Aqil F., Antioxidant and antimutagenic activity of Carum copticum fruit extracts. Toxicology in Vitro 2010 24 4 1243 1249 2-s2.0-77952959122 10.1016/j.tiv.2010.02.004
27. Maron D. M., Ames B. N., Revised methods for the Salmonella mutagenicity test. Mutation Research 1983 113 3-4 173 215 2-s2.0-0020533372 (Pubitemid 13120319)
28. Aqil F., Vadhanam M. V., Gupta R. C., Enhanced activity of punicalagin delivered via polymeric implants against benzo[a]pyrene-induced DNA adducts. Mutation Research: Genetic Toxicology and Environmental Mutagenesis 2012 743 1-2 59 66 2-s2.0-84857454932 10.1016/j.mrgentox.2011.12.022
29. Gupta R. C., Pfeifer G. P., 32P-postlabeling for detection of DNA adducts. Technologies for Detection of DNA Damage and Mutations 1996 New York, NY, USA Plenum Press 45 61
30. Steward W. P., Brown K., Cancer chemoprevention: a rapidly evolving field. British Journal of Cancer 2013 109 1 7 10.1038/bjc.2013.280
31. Fang A. H., Smith W. A., Vouros P., Gupta R. C., Identification and characterization of a novel benzo[a]pyrene-derived DNA adduct. Biochemical and Biophysical Research Communications 2001 281 2 383 389 2-s2.0-0034803233 10.1006/bbrc.2000.4161 (Pubitemid 32928167)
32. Arif J. M., Kunhi M., Siddiqui Y. M., El Sayed K. A., Orabi K. Y., Al-Hazzani A., Al-Ahdal M. N., Al-Khodairy F. M., Differential modulation of benzo[a]pyrene-derived DNA adducts in MCF-7 cells by marine compounds. International Journal of Cancer Prevention 2004 1 259 268
33. Miadokova E., Masterova I., Vlckova V., Duhova V., Toth J., Antimutagenic potential of homoisoflavonoids from Muscari racemosum. Journal of Ethnopharmacology 2002 81 3 381 386 10.1016/S0378-8741(02)00135-6 (Pubitemid 34786323)
34. Osborne M., Crosby N., Metabolism Benzopyrenes 1987 New York, NY, USA Cambridge University Press
35. Kaur S., Grover I. S., Singh M., Kaur S., Antimutagenicity of hydrolyzable tannins from Terminalia chebula in Salmonella typhimurium. Mutation Research: Genetic Toxicology and Environmental Mutagenesis 1998 419 1-3 169 179 2-s2.0-0032501161 10.1016/S1383-5718(98)00130-2 (Pubitemid 28512983)
36. Sayer J. M., Yagi H., Wood A. W., Conney A. H., Jerina D. M., Extremely facile reaction between the ultimate carcinogen benzo[a]pyrene-7,8-diol 9,10-epoxide and ellagic acid. Journal of the American Chemical Society 1982 104 20 5562 5564 2-s2.0-0020412768 (Pubitemid 13208757)
37. Larrosa M., Tomás-Barberán F. A., Espín J. C., The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway. Journal of Nutritional Biochemistry 2006 17 9 611 625 2-s2.0-33747026663 10.1016/j.jnutbio.2005.09.004 (Pubitemid 44205438)