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Volumn 19, Issue 2, 2014, Pages 161-168

PLGA nanoparticles production by emulsion and evaporation to encapsulate N-acetylcysteine (NAC);Producción de nanopartículas de PLGA por el método de emulsión y evaporación para encapsular N-Acetilcisteína (NAC)

Author keywords

N acetylcysteine; Nanoparticles; PLGA emulsion; Sonication

Indexed keywords


EID: 84901803524     PISSN: 01227483     EISSN: 20271352     Source Type: Journal    
DOI: 10.11144/Javeriana.SC19-2.pnpm     Document Type: Article
Times cited : (11)

References (30)
  • 1
    • 33750018320 scopus 로고    scopus 로고
    • Synthesis of Poly(DL-Lactide-Co-Glycolide) Nanoparticles with Entrapped Magnetite by Emulsion Evaporation Method
    • doi:10.1080/02726350600840696
    • Astete CE, Sabliov CM (2006) Synthesis of Poly(DL-Lactide-Co-Glycolide) Nanoparticles with Entrapped Magnetite by Emulsion Evaporation Method. Particulate Science and Technology 24(3):321-328 doi:10.1080/02726350600840696
    • (2006) Particulate Science and Technology , vol.24 , Issue.3 , pp. 321-328
    • Astete, C.E.1    Sabliov, C.M.2
  • 2
    • 20444459212 scopus 로고    scopus 로고
    • Pegylated poly(lactide) and poly(lactide-co-glycolide) nanoparticles: preparation, properties and possible applications in drug delivery
    • Retrieved from
    • Avgoustakis K (2004) Pegylated poly(lactide) and poly(lactide-co-glycolide) nanoparticles: preparation, properties and possible applications in drug delivery. Current Drug Delivery 1(4):321-33 Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/16305394
    • (2004) Current Drug Delivery , vol.1 , Issue.4 , pp. 321-333
    • Avgoustakis, K.1
  • 3
    • 34247639902 scopus 로고    scopus 로고
    • Haloperidol-loaded PLGA nanoparticles: systematic study of particle size and drug content
    • doi:10.1016/j.ijpharm.2006.11.061
    • Budhian A, Siegel SJ, Winey KI (2007) Haloperidol-loaded PLGA nanoparticles: systematic study of particle size and drug content. International Journal of Pharmaceutics 336(2):367-75 doi:10.1016/j.ijpharm.2006.11.061
    • (2007) International Journal of Pharmaceutics , vol.336 , Issue.2 , pp. 367-375
    • Budhian, A.1    Siegel, S.J.2    Winey, K.I.3
  • 4
    • 33750503424 scopus 로고    scopus 로고
    • Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery
    • doi:10.1016/j.biomaterials.2006.09.047
    • Cheng J, Teply BA, SherifiI, Sung J, Luther G, Gu FX, Farokhzad OC (2007) Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery. Biomaterials 28(5):869-76 doi:10.1016/j.biomaterials.2006.09.047
    • (2007) Biomaterials , vol.28 , Issue.5 , pp. 869-876
    • Cheng, J.1    Teply, B.A.2    Sherifi, I.3    Sung, J.4    Luther, G.5    Gu, F.X.6    Farokhzad, O.C.7
  • 7
    • 40549146613 scopus 로고    scopus 로고
    • Formulation and Characterization of Injectable Poly(-lactide-co- glycolide) Implants Loaded with N-Acetylcysteine, a MMP Inhibitor
    • Desai K, Mallery S, Schwendeman S (2008) Formulation and Characterization of Injectable Poly(-lactide-co- glycolide) Implants Loaded with N-Acetylcysteine, a MMP Inhibitor. Pharmaceutical Research 25(3):586-597
    • (2008) Pharmaceutical Research , vol.25 , Issue.3 , pp. 586-597
    • Desai, K.1    Mallery, S.2    Schwendeman, S.3
  • 8
    • 34547887282 scopus 로고    scopus 로고
    • Fluorescent biodegradable PLGA particles with narrow size distributions: preparation by means of selective centrifugation
    • doi:10.1016/j.ijpharm.2007.05.001
    • Gaumet M, Gurny R, Delie F (2007) Fluorescent biodegradable PLGA particles with narrow size distributions: preparation by means of selective centrifugation. International Journal of Pharmaceutics 342(1-2):222-30 doi:10.1016/j.ijpharm.2007.05.001
    • (2007) International Journal of Pharmaceutics , vol.342 , Issue.1-2 , pp. 222-230
    • Gaumet, M.1    Gurny, R.2    Delie, F.3
  • 9
    • 79952085221 scopus 로고    scopus 로고
    • Poly (DL-lactide-co-glycolide) (PLGA) nanoparticles with entrapped trans-cinnamaldehyde and eugenol for antimicrobial delivery applications
    • doi:10.1111/j.1750-3841.2010.01985.x
    • Gomes C, Moreira RG, Castell-Perez E (2011) Poly (DL-lactide-co-glycolide) (PLGA) nanoparticles with entrapped trans-cinnamaldehyde and eugenol for antimicrobial delivery applications. Journal of Food Science 76(2):16-24 doi:10.1111/j.1750-3841.2010.01985.x
    • (2011) Journal of Food Science , vol.76 , Issue.2 , pp. 16-24
    • Gomes, C.1    Moreira, R.G.2    Castell-Perez, E.3
  • 12
    • 0034580371 scopus 로고    scopus 로고
    • The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices
    • Retrieved from
    • Jain R (2000) The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices. Biomaterials 21(23):2475-90 Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/11055295
    • (2000) Biomaterials , vol.21 , Issue.23 , pp. 2475-2490
    • Jain, R.1
  • 13
    • 77949538412 scopus 로고    scopus 로고
    • Effects of poly(lactic-co-glycolic acid) (PLGA) degradability on the apatite-forming capacity of electrospun PLGA/SiO(2)-CaO nonwoven composite fabrics
    • doi:10.1002/jbm.b.31578
    • Kim IA, Rhee SH (2010) Effects of poly(lactic-co-glycolic acid) (PLGA) degradability on the apatite-forming capacity of electrospun PLGA/SiO(2)-CaO nonwoven composite fabrics. Journal of Biomedical Materials Research Part B Applied Biomaterials 93(1):218-26 doi:10.1002/jbm.b.31578
    • (2010) Journal of Biomedical Materials Research Part B Applied Biomaterials , vol.93 , Issue.1 , pp. 218-226
    • Kim, I.A.1    Rhee, S.H.2
  • 14
    • 70450221930 scopus 로고    scopus 로고
    • Biodegradable polymeric nanoparticles based drug delivery systems
    • doi:10.1016/j.colsurfb.2009.09.001
    • Kumari A, Yadav SK, Yadav SC (2010) Biodegradable polymeric nanoparticles based drug delivery systems. Colloids and Surfaces B Biointerfaces 75(1):1-18 doi:10.1016/j.colsurfb.2009.09.001
    • (2010) Colloids and Surfaces B Biointerfaces , vol.75 , Issue.1 , pp. 1-18
    • Kumari, A.1    Yadav, S.K.2    Yadav, S.C.3
  • 15
    • 12344337457 scopus 로고    scopus 로고
    • PLGA nanoparticles containing praziquantel: effect of formulation variables on size distribution
    • doi:10.1016/j.ijpharm.2004.11.027
    • Mainardes RM, Evangelista RC (2005) PLGA nanoparticles containing praziquantel: effect of formulation variables on size distribution. International Journal of Pharmaceutics 290(1-2):137-44 doi:10.1016/j.ijpharm.2004.11.027
    • (2005) International Journal of Pharmaceutics , vol.290 , Issue.1-2 , pp. 137-144
    • Mainardes, R.M.1    Evangelista, R.C.2
  • 16
    • 51649091581 scopus 로고    scopus 로고
    • Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents
    • doi:10.1016/j.ijpharm.2008.07.015
    • Mitsopoulos P, Omri A, Alipour M, Vermeulen N, Smith MG, Suntres ZE (2008) Effectiveness of liposomal-N-acetylcysteine against LPS-induced lung injuries in rodents. International Journal of Pharmaceutics 363(1-2):106-11 doi:10.1016/j.ijpharm.2008.07.015
    • (2008) International Journal of Pharmaceutics , vol.363 , Issue.1-2 , pp. 106-111
    • Mitsopoulos, P.1    Omri, A.2    Alipour, M.3    Vermeulen, N.4    Smith, M.G.5    Suntres, Z.E.6
  • 19
    • 58149092257 scopus 로고    scopus 로고
    • Dendrimer-Drug Conjugates for Tailored Intracellular Drug Release Based on Glutathione Levels
    • doi:10.1021/bc800342d
    • Navath RS, Kurtoglu YE, Wang B, Kannan S, Romero R, Kannan RM (2008) Dendrimer-Drug Conjugates for Tailored Intracellular Drug Release Based on Glutathione Levels. Bioconjugate Chemistry 19(12):2446-2455 doi:10.1021/bc800342d
    • (2008) Bioconjugate Chemistry , vol.19 , Issue.12 , pp. 2446-2455
    • Navath, R.S.1    Kurtoglu, Y.E.2    Wang, B.3    Kannan, S.4    Romero, R.5    Kannan, R.M.6
  • 20
    • 77649185801 scopus 로고    scopus 로고
    • Stimuli-responsive star poly(ethylene glycol) drug conjugates for improved intracellular delivery of the drug in neuroinflammation
    • doi:10.1016/j.jconrel.2009.10.035
    • Navath RS, Wang B, Kannan S, Romero R, Kannan RM (2010) Stimuli-responsive star poly(ethylene glycol) drug conjugates for improved intracellular delivery of the drug in neuroinflammation. Journal of Controlled Release: Official Journal of the Controlled Release Society 142(3)447-56 doi:10.1016/j.jconrel.2009.10.035
    • (2010) Journal of Controlled Release: Official Journal of the Controlled Release Society , vol.142 , Issue.3 , pp. 447-456
    • Navath, R.S.1    Wang, B.2    Kannan, S.3    Romero, R.4    Kannan, R.M.5
  • 21
    • 84255182664 scopus 로고    scopus 로고
    • Effects of Microemulsion Preparation Conditions on Drug Encapsulation Efficiency of PLGA Nanoparticles
    • In, Symposium;4th, Nanoscience and nanotechnology, doi:10.1063/1.3667217
    • Ng SH, Ooi IH, Iskandar F, Abdullah M (2011) Effects of Microemulsion Preparation Conditions on Drug Encapsulation Efficiency of PLGA Nanoparticles. In: AIP Conference proceedings Nanoscience and nanotechnology, Symposium;4th, Nanoscience and nanotechnology, pp 47-50 doi:10.1063/1.3667217
    • (2011) AIP Conference proceedings Nanoscience and nanotechnology , pp. 47-50
    • Ng, S.H.1    Ooi, I.H.2    Iskandar, F.3    Abdullah, M.4
  • 22
    • 84901754206 scopus 로고    scopus 로고
    • The Neuroprotective Efficacy of Antioxidants Against In Vitro Models of Oxidative Stress and Their Theoretical Application Via Intravitreal Injection Encapsulated in Nanoparticles
    • University of North Texas Health Science Center at Fort Worth. Retrieved from
    • Ondricek AJ (2010) The Neuroprotective Efficacy of Antioxidants Against In Vitro Models of Oxidative Stress and Their Theoretical Application Via Intravitreal Injection Encapsulated in Nanoparticles. University of North Texas Health Science Center at Fort Worth. Retrieved from http://gradworks.umi.com/34/02/3402967.html
    • (2010)
    • Ondricek, A.J.1
  • 23
    • 23144456869 scopus 로고    scopus 로고
    • Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(l)lactide nanoparticles
    • doi:10.1208/pt050116
    • Peltonen L, Aitta J, Hyvönen S, Karjalainen M, Hirvonen J (2004). Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly(l)lactide nanoparticles. AAPS PharmSciTech 5(1):16 doi:10.1208/pt050116
    • (2004) AAPS PharmSciTech , vol.5 , Issue.1 , pp. 16
    • Peltonen, L.1    Aitta, J.2    Hyvönen, S.3    Karjalainen, M.4    Hirvonen, J.5
  • 24
    • 0020358055 scopus 로고
    • Colorimetric determination of acetylcysteine, penicillamine, and mercaptopropionylglycine in pharmaceutical dosage forms
    • Retrieved from
    • Raggi M, Cavrini V, Di Pietra M (1982). Colorimetric determination of acetylcysteine, penicillamine, and mercaptopropionylglycine in pharmaceutical dosage forms. Journal of Pharmaceutical Sciences 71(12): 1384-6 Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/7153888
    • (1982) Journal of Pharmaceutical Sciences , vol.71 , Issue.12 , pp. 1384-1386
    • Raggi, M.1    Cavrini, V.2    Di Pietra, M.3
  • 25
    • 0347761356 scopus 로고    scopus 로고
    • Preparation and characterization of cationic PLGA nanospheres as DNA carriers
    • doi:10.1016/j.biomaterials.2003.08.069
    • Ravi Kumar MNV, Bakowsky U, Lehr CM (2004) Preparation and characterization of cationic PLGA nanospheres as DNA carriers. Biomaterials 25(10):1771-1777 doi:10.1016/j.biomaterials.2003.08.069
    • (2004) Biomaterials , vol.25 , Issue.10 , pp. 1771-1777
    • Ravi Kumar, M.N.V.1    Bakowsky, U.2    Lehr, C.M.3
  • 27
    • 38549178381 scopus 로고    scopus 로고
    • PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride: systematic study of particle size and drug entrapment efficiency
    • doi:10.1016/j.ijpharm.2007.08.034
    • Song X, Zhao Y, Wu W, Bi Y, Cai Z, Chen Q, Hou S (2008b) PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride: systematic study of particle size and drug entrapment efficiency. International Journal of Pharmaceutics 350(1-2):320-9 doi:10.1016/j.ijpharm.2007.08.034
    • (2008) International Journal of Pharmaceutics , vol.350 , Issue.1-2 , pp. 320-329
    • Song, X.1    Zhao, Y.2    Wu, W.3    Bi, Y.4    Cai, Z.5    Chen, Q.6    Hou, S.7
  • 28
    • 64149096611 scopus 로고    scopus 로고
    • Anti-oxidants for therapeutic use: why are only a few drugs in clinical use?
    • doi:10.1016/j.addr.2009.03.002
    • Suzuki K (2009) Anti-oxidants for therapeutic use: why are only a few drugs in clinical use? Advanced Drug Delivery Reviews 61(4):28-79 doi:10.1016/j.addr.2009.03.002
    • (2009) Advanced Drug Delivery Reviews , vol.61 , Issue.4 , pp. 28-79
    • Suzuki, K.1
  • 29
    • 67649992320 scopus 로고    scopus 로고
    • Anti-inflammatory and anti-oxidant activity of anionic dendrimer-N-acetyl cysteine conjugates in activated microglial cells
    • doi:10.1016/j.ijpharm.2009.04.050
    • Wang B, Navath RS, Romero R, Kannan S, Kannan R (2009) Anti-inflammatory and anti-oxidant activity of anionic dendrimer-N-acetyl cysteine conjugates in activated microglial cells. International Journal of Pharmaceutics 377(1-2):159-68 doi:10.1016/j.ijpharm.2009.04.050
    • (2009) International Journal of Pharmaceutics , vol.377 , Issue.1-2 , pp. 159-168
    • Wang, B.1    Navath, R.S.2    Romero, R.3    Kannan, S.4    Kannan, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.