Gly25-Ser26 amyloid β-protein structural isomorphs produce distinct Aβ42 conformational dynamics and assembly characteristics

Journal of Molecular Biology

Volumn 426, Issue 13, 2014, Pages 2422-2441

  Roychaudhuri, Robin ^a   Lomakin, Aleksey ^b   Bernstein, Summer ^c   Zheng, Xueyun ^c   Condron, Margaret M ^a   Benedek, George B ^b   Bowers, Michael ^c   Teplow, David B ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; amyloid protein; fibril formation; ion mobility spectroscopy mass spectrometry; oligomerization

Indexed keywords

AMYLOID BETA PROTEIN; DIPEPTIDE; GLYCINE; SERINE; THIOFLAVINE;

ARTICLE; BETA SHEET; CLICK CHEMISTRY; CONFORMATIONAL TRANSITION; HYDRODYNAMICS; ION MOBILITY SPECTROMETRY; LIGHT SCATTERING; MASS SPECTROMETRY; OLIGOMERIZATION; PH; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN CROSS LINKING; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS;

ALZHEIMER'S DISEASE; AMYLOID Β-PROTEIN; FIBRIL FORMATION; ION MOBILITY SPECTROSCOPY-MASS SPECTROMETRY; OLIGOMERIZATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; BIOPHYSICAL PHENOMENA; CLICK CHEMISTRY; GLYCINE; HUMANS; MOLECULAR DYNAMICS SIMULATION; PEPTIDE FRAGMENTS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN ISOFORMS; PROTEIN MULTIMERIZATION; SERINE;

EID: 84901786895     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2014.04.004     Document Type: Article

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