Synthesis of gelatin-γ-Polyglutamic acid-based hydrogel for the in vitro controlled release of epigallocatechin gallate (EGCG) from Camellia sinensis

Polymers

Volumn 6, Issue 1, 2014, Pages 39-58

  Garcia, John Philip Domondon ^a   Hsieh, Ming Fa ^b   Doma Jr , Bonifacio Tobias ^a   Peruelo, Dorothy Caminos ^c   Chen, Ing Ho ^d   Lee, Hung Maan ^d,e  

^a MAPUA UNIVERSITY   (Philippines)

^b CHUNG YUAN CHRISTIAN UNIVERSITY   (Taiwan)

^c XAVIER UNIVERSITY   (Philippines)

^d TZU CHI UNIVERSITY   (Taiwan)

^e TAOYUAN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

EGCG; Gelatin; in vitro drug release; Ionic hydrogel; PGA

Indexed keywords

BIOCHEMISTRY; BIOMATERIALS; DIFFERENTIAL SCANNING CALORIMETRY; DRUG PRODUCTS; INFRARED SPECTROSCOPY; SCANNING ELECTRON MICROSCOPY;

CONTROLLED TEMPERATURE; CROSS-LINKED HYDROGELS; EGCG; EPIGALLOCATECHIN GALLATE; GELATIN; IN-VITRO; IONIC HYDROGELS; PHYSICO-CHEMICAL CHARACTERIZATION;

HYDROGELS;

EID: 84901777112     PISSN: None     EISSN: 20734360     Source Type: Journal    
DOI: 10.3390/polym6010039     Document Type: Article

References (42)

1. Perva-Uzunalić, A.; Škerget, M.; Knez, Ž.; Weinreich, B.; Otto, F.; Grüner, S. Extraction of active ingredients from green tea (Camellia sinensis): Extraction efficiency of major catechins and caffeine. Food Chem. 2006, 96, 597-605.
2. Jun, X.; Shuo, Z.; Bingbing, L.; Rui, Z.; Ye, L.; Deji, S.; Guofeng, Z. Separation of major catechins from green tea by ultrahigh pressure extraction. Int. J. Pharm. 2010, 386, 229-231.
3. Nagle, D.G.; Ferreira, D.; Zhou, Y.D. Epigallocatechin-3-gallate (egcg): Chemical and biomedical perspectives. Phytochemistry 2006, 67, 1849-1855.
4. Ho, H.-Y.; Cheng, M.-L.; Weng, S.-F.; Leu, Y.-L.; Chiu, D.T.-Y. Antiviral effect of epigallocatechin gallate on enterovirus 71. J. Agric. Food Chem. 2009, 57, 6140-6147.
5. Yang, C.S.; Wang, X.; Lu, G.; Picinich, S.C. Cancer prevention by tea: Animal studies, molecular mechanisms and human relevance. Nat. Rev. Cancer 2009, 9, 429-439.
6. Row, K.H.; Jin, Y. Recovery of catechin compounds from korean tea by solvent extraction. Bioresour. Technol. 2006, 97, 790-793.
7. Dugas, A.J., Jr.; Castañeda-Acosta, J.; Bonin, G.C.; Price, K.L.; Fischer, N.H.; Winston, G.W. Evaluation of the total peroxyl radical-scavenging capacity of flavonoids: Structure-activity relationships. J. Nat. Prod. 2000, 63, 327-331.
8. Rice-Evans, C.A.; Miller, N.J.; Paganga, G. Structure-antioxidant activity relationships of flavonoids and phenolic acids. Free Radic. Biol. Med. 1996, 20, 933-956.
9. Yang, C.S.; Sang, S.; Lambert, J.D.; Lee, M.-J. Bioavailability issues in studying the health effects of plant polyphenolic compounds. Mol. Nutr. Food Res. 2008, 52, S139-S151.
10. Zhu, M.; Chen, Y.; Li, R.C. Oral absorption and bioavailability of tea catechins. Planta Med. 2000, 66, 444-447.
11. Green, R.J.; Murphy, A.S.; Schulz, B.; Watkins, B.A.; Ferruzzi, M.G. Common tea formulations modulate in vitro digestive recovery of green tea catechins. Mol. Nutr. Food Res. 2007, 51, 1152-1162.
12. Huo, C.; Wan, S.B.; Lam, W.H.; Li, L.; Wang, Z.; Landis-Piwowar, K.R.; Chen, D.; Dou, Q.P.; Chan, T.H. The challenge of developing green tea polyphenols as therapeutic agents. Inflammopharmacology 2008, 16, 248-252.
13. Wang, X.; Wang, Y.-W.; Huang, Q. Enhancing Stability and Oral Bioavailability of Polyphenols Using Nanoemulsions. In Micro/Nanoencapsulation of Active Food Ingredients; American Chemical Society: Washington, DC, USA, 2009; Volume 1007, pp. 198-212.
14. Lee, J.-S.; Chung, D.; Lee, H.G. Optimization of calcium pectinate gel beads for sustained-release of catechin using response surface methodology. Int. J. Biol. Macromol. 2008, 42, 340-347.
15. Renò, F.; Carniato, F.; Rizzi, M.; Marchese, L.; Laus, M.; Antonioli, D. Poss/gelatin-polyglutamic acid hydrogel composites: Preparation, biological and mechanical characterization. J. Appl. Polym. Sci. 2013, 129, 699-706.
16. Einerson, N.J.; Stevens, K.R.; Kao, W.J. Synthesis and physicochemical analysis of gelatin-based hydrogels for drug carrier matrices. Biomaterials 2003, 24, 509-523.
17. Layman, H.; Spiga, M.-G.; Brooks, T.; Pham, S.; Webster, K.A.; Andreopoulos, F.M. The effect of the controlled release of basic fibroblast growth factor from ionic gelatin-based hydrogels on angiogenesis in a murine critical limb ischemic model. Biomaterials 2007, 28, 2646-2654.
18. Silva, A.K.A.; Richard, C.; Bessodes, M.; Scherman, D.; Merten, O.-W. Growth factor delivery approaches in hydrogels. Biomacromolecules 2008, 10, 9-18.
19. Young, S.; Wong, M.; Tabata, Y.; Mikos, A.G. Gelatin as a delivery vehicle for the controlled release of bioactive molecules. J. Control. Release 2005, 109, 256-274.
20. Tang, D.-W.; Yu, S.-H.; Ho, Y.-C.; Huang, B.-Q.; Tsai, G.-J.; Hsieh, H.-Y.; Sung, H.-W.; Mi, F.-L. Characterization of tea catechins-loaded nanoparticles prepared from chitosan and an edible polypeptide. Food Hydrocoll. 2013, 30, 33-41.
21. Magnin, D.; Lefebvre, J.; Chornet, E.; Dumitriu, S. Physicochemical and structural characterization of a polyionic matrix of interest in biotechnology, in the pharmaceutical and biomedical fields. Carbohydr. Polym. 2004, 55, 437-453.
22. Chen, C.-H.; Hsieh, M.-F.; Ho, Y.-N.; Huang, C.-M.; Lee, J.-S.; Yang, C.-Y.; Chang, Y. Enhancement of catechin skin permeation via a newly fabricated mpeg-pcl-graft-2-hydroxycellulose membrane. J. Membr. Sci. 2011, 371, 134-140.
23. Philip, A.K.; Philip, B. Colon targeted drug delivery systems: A review on primary and novel approaches. Oman Med. J. 2010, 25, 70-78.
24. Sigma-Aldrich, Product Information Sheet: Gelatin; Sigma-Aldrich, Inc.: St. Louis, MO, USA, 2013.
25. Gorgieva, S.; Kokol, V. Collagen- vs. Gelatine-Based Biomaterials and Their Biocompatibility: Review and Perspective. In Biomaterials Applications for Nanomedicine Pignatello, R., Ed.; InTech: Rijeka, Croatia, 2011; p. 458.
26. Shih, I.-L.; Van, Y.-T. The production of poly-(γ-glutamic acid) from microorganisms and its various applications. Bioresour. Technol. 2001, 79, 207-225.
27. Lin, C.-C.; Metters, A.T. Hydrogels in controlled release formulations: Network design and mathematical modeling. Adv. Drug Deliv. Rev. 2006, 58, 1379-1408.
28. Hsu, S.-H.; Lin, C.-H. The properties of gelatin-poly (γ-glutamic acid) hydrogels as biological glues. Biorheology 2007, 44, 17-28.
29. Rathna, G.V.N. Gelatin hydrogels: Enhanced biocompatibility, drug release and cell viability. J. Mater. Sci: Mater. Med. 2008, 19, 2351-2358.
30. Lin, Y.-H.; Lin, J.-H.; Peng, S.-F.; Yeh, C.-L.; Chen, W.-C.; Chang, T.-L.; Liu, M.-J.; Lai, C.-H. Multifunctional gentamicin supplementation of poly(γ-glutamic acid)-based hydrogels for wound dressing application. J. Appl. Polym. Sci. 2011, 120, 1057-1068.
31. Pinotti, A.; García, M.A.; Martino, M.N.; Zaritzky, N.E. Study on microstructure and physical properties of composite films based on chitosan and methylcellulose. Food Hydrocoll. 2007, 21, 66-72.
32. Chen, Y.-C.; Yu, S.-H.; Tsai, G.-J.; Tang, D.-W.; Mi, F.-L.; Peng, Y.-P. Novel technology for the preparation of self-assembled catechin/gelatin nanoparticles and their characterization. J. Agric. Food Chem. 2010, 58, 6728-6734.
33. Wanchoo, R.K.; Sharma, P.K. Viscometric study on the compatibility of some water-soluble polymer-Polymer mixtures. Eur. Polym. J. 2003, 39, 1481-1490.
34. Zhu, B.; Li, J.; He, Y.; Yoshie, N.; Inoue, Y. Hydrogen-bonding interaction and crystalline morphology in the binary blends of poly(ε-caprolactone) and polyphenol catechin. Macromol. Biosci. 2003, 3, 684-693.
35. Ho, G.-H.; Ho, T.-I.; Hsieh, K.-H.; Su, Y.-C.; Lin, P.-Y.; Yang, J.; Yang, K.-H.; Yang, S.-C. γ-polyglutamic acid produced by Bacillus subtilis (natto): Structural characteristics, chemical properties, and biological functionalities. J. Chin. Chem. Soc. 2006, 53, 1363-1384.
36. Fakirov, S. Gelatin and Gelatin-Based Biodegradable Composites: Manufacturing, Properties, and Biodegradation Behavior. In Handbook of Engineering Biopolymers: Homopolymers, Blends, and Composites; Fakirov, S., Bhattacharya, D., Eds.; Carl Hanser Verlag: München, Germany, 2007.
37. Amin, S.; Rajabnezhad, S.; Kohli, K. Hydrogels as potential drug delivery systems. Sci. Res. Essay 2009, 3, 1175-1183.
38. Bajpai, S.K.; Dubey, S. Synthesis and swelling kinetics of a pH-sensitive terpolymeric hydrogel system. Iran. Polym. J. 2004, 13, 189-203.
39. Xing, L.; Dawei, C.; Liping, X.; Rongqing, Z. Oral colon-specific drug delivery for bee venom peptide: Development of a coated calcium alginate gel beads-entrapped liposome. J. Control. Release 2003, 93, 293-300.
40. Siepmann, J.; Peppas, N.A. Higuchi equation: Derivation, applications, use and misuse. Int. J. Pharm. 2011, 418, 6-12.
41. Hu, B.; Ting, Y.W.; Yang, X.Q.; Tang, W.P.; Zeng, X.X.; Huang, Q.R. Nanochemoprevention by encapsulation of (-)-epigallocatechin-3-gallate with bioactive peptides/chitosan nanoparticles for enhancement of its bioavailability. Chem. Commun. 2012, 48, 2421-2423.
42. Shutava, T.G.; Balkundi, S.S.; Vangala, P.; Steffan, J.J.; Bigelow, R.L.; Cardelli, J.A.; O'Neal, D.P.; Lvov, Y.M. Layer-by-layer-coated gelatin nanoparticles as a vehicle for delivery of natural polyphenols. ACS Nano 2009, 3, 1877-1885.