DYRK1A phoshorylates histone H3 to differentially regulate the binding of HP1 isoforms and antagonize HP1-mediated transcriptional repression

EMBO Reports

Volumn 15, Issue 6, 2014, Pages 686-694

  Jang, Suk Min ^a,b,c   Azebi, Saliha ^a,b,c   Soubigou, Guillaume ^a   Muchardt, Christian ^a,b  

^a INSTITUT PASTEUR   (France)

^b CNRS   (France)

^c SORBONNE UNIVERSITÉ   (France)

Author keywords

chromatin silencing; cytokine; epigenetic; histone code; inflammation

Indexed keywords

DYRK1A PROTEIN; HETEROCHROMATIN PROTEIN 1; HISTONE H3; MEMBRANE PROTEIN; SERINE; THREONINE; UNCLASSIFIED DRUG; DYRK KINASE; HETEROCHROMATIN-SPECIFIC NONHISTONE CHROMOSOMAL PROTEIN HP-1; HISTONE; ISOPROTEIN; NONHISTONE PROTEIN; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE;

ANIMAL CELL; ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMOSOME 21; CONTROLLED STUDY; GENE; GENE REPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; STRESS; TRANSCRIPTION REGULATION; CHROMATIN IMMUNOPRECIPITATION; DNA MICROARRAY; EXON; GENE EXPRESSION REGULATION; GENETICS; IMMUNOBLOTTING; METABOLISM; PHOSPHORYLATION; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; CHROMOSOMAL PROTEINS, NON-HISTONE; EXONS; GENE EXPRESSION REGULATION; HISTONES; HUMANS; IMMUNOBLOTTING; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84901752073     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201338356     Document Type: Article

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