메뉴 건너뛰기




Volumn 61, Issue 5, 2014, Pages 471-480

LRH-1 heterozygous knockout mice are prone to mild obesity

Author keywords

CYP7A1; CYP8B1; Liver receptor homologue 1; Obesity; Small heterodimer partner

Indexed keywords

LIVER RECEPTOR HOMOLOG 1; CELL RECEPTOR; GLUCOSE; NR5A2 PROTEIN, HUMAN;

EID: 84901747677     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.EJ14-0017     Document Type: Article
Times cited : (10)

References (26)
  • 1
    • 2942657650 scopus 로고    scopus 로고
    • Medical consequences of obesity
    • Bray GA (2004) Medical consequences of obesity. J Clin Endocrinol Metab 89: 2583-2589.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2583-2589
    • Bray, G.A.1
  • 2
    • 0035936764 scopus 로고    scopus 로고
    • Obesity and the regulation of energy balance
    • Spiegelman BM, Flier JS (2001) Obesity and the regulation of energy balance. Cell 104: 531-543
    • (2001) Cell , vol.104 , pp. 531-543
    • Spiegelman, B.M.1    Flier, J.S.2
  • 4
    • 60549102722 scopus 로고    scopus 로고
    • Gene-environment interaction and obesity
    • Qi L, Cho YA (2008) Gene-environment interaction and obesity. Nutr Rev 66: 684-694.
    • (2008) Nutr Rev , vol.66 , pp. 684-694
    • Qi, L.1    Cho, Y.A.2
  • 5
    • 84876267697 scopus 로고    scopus 로고
    • Cortisol, obesity, and the metabolic syndrome: A cross-sectional study of obese subjects and review of the literature
    • Abraham SB, Rubino D, Sinaii N, Ramsey S, Nieman LK (2013) Cortisol, obesity, and the metabolic syndrome: a cross-sectional study of obese subjects and review of the literature. Obesity (Silver Spring) 21:E105-117.
    • (2013) Obesity (Silver Spring) , vol.21 , pp. 105-117
    • Abraham, S.B.1    Rubino, D.2    Sinaii, N.3    Ramsey, S.4    Nieman, L.K.5
  • 6
    • 0035895268 scopus 로고    scopus 로고
    • Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects
    • Nishigori H, Tomura H, Tonooka N, Kanamori M, Yamada S, et al. (2001) Mutations in the small heterodimer partner gene are associated with mild obesity in Japanese subjects. Proc Natl Acad Sci U S A 98: 575-580.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 575-580
    • Nishigori, H.1    Tomura, H.2    Tonooka, N.3    Kanamori, M.4    Yamada, S.5
  • 7
    • 79958243702 scopus 로고    scopus 로고
    • Role of nuclear receptor SHP in metabolism and cancer
    • Zhang Y, Hagedorn CH, Wang L (2011) Role of nuclear receptor SHP in metabolism and cancer. Biochim Biophys Acta 1812: 893-908.
    • (2011) Biochim Biophys Acta , vol.1812 , pp. 893-908
    • Zhang, Y.1    Hagedorn, C.H.2    Wang, L.3
  • 8
    • 2342459110 scopus 로고    scopus 로고
    • LRH-1: An orphan nuclear receptor involved in development, metabolism and steroidogenesis
    • Fayard E, Auwerx J, Schoonjans K (2004) LRH-1: an orphan nuclear receptor involved in development, metabolism and steroidogenesis. Trends Cell Biol 14: 250-260.
    • (2004) Trends Cell Biol , vol.14 , pp. 250-260
    • Fayard, E.1    Auwerx, J.2    Schoonjans, K.3
  • 9
    • 0033636789 scopus 로고    scopus 로고
    • Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors
    • Lu TT, Makishima M, Repa JJ, Schoonjans K, Kerr TA, et al. (2000) Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. Mol Cell 6: 507-515.
    • (2000) Mol Cell , vol.6 , pp. 507-515
    • Lu, T.T.1    Makishima, M.2    Repa, J.J.3    Schoonjans, K.4    Kerr, T.A.5
  • 10
    • 0033637121 scopus 로고    scopus 로고
    • A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
    • Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, et al. (2000) A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. Mol Cell 6: 517-526.
    • (2000) Mol Cell , vol.6 , pp. 517-526
    • Goodwin, B.1    Jones, S.A.2    Price, R.R.3    Watson, M.A.4    McKee, D.D.5
  • 11
    • 31444454037 scopus 로고    scopus 로고
    • Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
    • Watanabe M, Houten SM, Mataki C, Christoffolete MA, Kim BW, et al. (2006) Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 439:484-489.
    • (2006) Nature , vol.439 , pp. 484-489
    • Watanabe, M.1    Houten, S.M.2    Mataki, C.3    Christoffolete, M.A.4    Kim, B.W.5
  • 12
    • 84883245757 scopus 로고    scopus 로고
    • Transcriptional regulation of adipocyte formation by the liver receptor homologue 1 (Lrh1)-Small hetero-dimerization partner (Shp) network
    • Mrosek N, Meissburger B, Mataki C, Roeder E, Ukropec J, et al. (2013) Transcriptional regulation of adipocyte formation by the liver receptor homologue 1 (Lrh1)-Small hetero-dimerization partner (Shp) network. Mol Metab 2:314-323.
    • (2013) Mol Metab , vol.2 , pp. 314-323
    • Mrosek, N.1    Meissburger, B.2    Mataki, C.3    Roeder, E.4    Ukropec, J.5
  • 13
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • Folch J, Lees M, Sloane Stanley GH (1957) A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226: 497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 14
    • 0033536005 scopus 로고    scopus 로고
    • CPF: An orphan nuclear receptor that regulates liverspecific expression of the human cholesterol 7alphahydroxylase gene
    • Nitta M, Ku S, Brown C, Okamoto AY, Shan B. (1999) CPF: an orphan nuclear receptor that regulates liverspecific expression of the human cholesterol 7alphahydroxylase gene. Proc Natl Acad Sci U S A 96:6660-6665.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 6660-6665
    • Nitta, M.1    Ku, S.2    Brown, C.3    Okamoto, A.Y.4    Shan, B.5
  • 15
    • 36849005392 scopus 로고    scopus 로고
    • Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1
    • Mataki C, Magnier BC, Houten SM, Annicotte JS, Argmann C et al. (2007) Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1. Mol Cell Biol 27:8330-8339.
    • (2007) Mol Cell Biol , vol.27 , pp. 8330-8339
    • Mataki, C.1    Magnier, B.C.2    Houten, S.M.3    Annicotte, J.S.4    Argmann, C.5
  • 16
    • 44649202231 scopus 로고    scopus 로고
    • Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis
    • Lee YK, Schmidt DR, Cummins CL, Choi M, Peng L, et al. (2008) Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. Mol Endocrinol 22:1345-1356.
    • (2008) Mol Endocrinol , vol.22 , pp. 1345-1356
    • Lee, Y.K.1    Schmidt, D.R.2    Cummins, C.L.3    Choi, M.4    Peng, L.5
  • 17
    • 79957512391 scopus 로고    scopus 로고
    • Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration
    • Out C, Hageman J, Bloks VW, Gerrits H, Sollewijn Gelpke MD, et al. (2011) Liver receptor homolog-1 is critical for adequate up-regulation of Cyp7a1 gene transcription and bile salt synthesis during bile salt sequestration. Hepatology 53:2075-2085.
    • (2011) Hepatology , vol.53 , pp. 2075-2085
    • Out, C.1    Hageman, J.2    Bloks, V.W.3    Gerrits, H.4    Sollewijn Gelpke, M.D.5
  • 18
    • 84862909056 scopus 로고    scopus 로고
    • Glucose and insulin induction of bile acid synthesis: Mechanisms and implication in diabetes and obesity
    • Li T, Francl JM, Boehme S, Ochoa A, Zhang Y, Klaassen CD, et al. (2012) Glucose and insulin induction of bile acid synthesis: mechanisms and implication in diabetes and obesity. J Biol Chem 287:1861-1873.
    • (2012) J Biol Chem , vol.287 , pp. 1861-1873
    • Li, T.1    Francl, J.M.2    Boehme, S.3    Ochoa, A.4    Zhang, Y.5    Klaassen, C.D.6
  • 19
    • 84864752368 scopus 로고    scopus 로고
    • LRH-1-dependent glucose sensing determines intermediary metabolism in liver
    • Oosterveer MH, Mataki C, Yamamoto H, Harach T, Moullan N, et al. (2012) LRH-1-dependent glucose sensing determines intermediary metabolism in liver. J Clin Invest 122:2817-26.
    • (2012) J Clin Invest , vol.122 , pp. 2817-2826
    • Oosterveer, M.H.1    Mataki, C.2    Yamamoto, H.3    Harach, T.4    Moullan, N.5
  • 20
    • 84878518534 scopus 로고    scopus 로고
    • Recent progress on the role of ChREBP in glucose and lipid metabolism
    • Iizuka K. (2013) Recent progress on the role of ChREBP in glucose and lipid metabolism. Endocr J 60:543-555.
    • (2013) Endocr J , vol.60 , pp. 543-555
    • Iizuka, K.1
  • 21
    • 84876990345 scopus 로고    scopus 로고
    • Role of glucose-6-phosphate and xylulose-5-phosphate in the regulation of glucose-stimulated gene expression in the pancreatic β cell line, INS-1E
    • Iizuka K, Wu W, Horikawa Y, Takeda J. (2013) Role of glucose-6-phosphate and xylulose-5-phosphate in the regulation of glucose-stimulated gene expression in the pancreatic β cell line, INS-1E. Endocr J 60:473-482.
    • (2013) Endocr J , vol.60 , pp. 473-482
    • Iizuka, K.1    Wu, W.2    Horikawa, Y.3    Takeda, J.4
  • 22
    • 33947246606 scopus 로고    scopus 로고
    • Expression profiling of liver receptor homologue 1 (LRH-1) in mouse tissues using tissue microarray
    • Higashiyama H, Kinoshita M, Asano S (2007) Expression profiling of liver receptor homologue 1 (LRH-1) in mouse tissues using tissue microarray. J Mol Histol 38: 45-52.
    • (2007) J Mol Histol , vol.38 , pp. 45-52
    • Higashiyama, H.1    Kinoshita, M.2    Asano, S.3
  • 23
    • 20244381404 scopus 로고    scopus 로고
    • Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development
    • Gu P, Goodwin B, Chung AC, Xu X, Wheeler DA, et al. (2005) Orphan nuclear receptor LRH-1 is required to maintain Oct4 expression at the epiblast stage of embryonic development. Mol Cell Biol 25:3492-3505.
    • (2005) Mol Cell Biol , vol.25 , pp. 3492-3505
    • Gu, P.1    Goodwin, B.2    Chung, A.C.3    Xu, X.4    Wheeler, D.A.5
  • 24
    • 0036153668 scopus 로고    scopus 로고
    • Knockout mice lacking steroidogenic factor 1 are a novel genetic model of hypothalamic obesity
    • Majdic G, Young M, Gomez-Sanchez E, Anderson P, Szczepaniak LS, et al. (2002) Knockout mice lacking steroidogenic factor 1 are a novel genetic model of hypothalamic obesity. Endocrinology 143:607-614.
    • (2002) Endocrinology , vol.143 , pp. 607-614
    • Majdic, G.1    Young, M.2    Gomez-Sanchez, E.3    Anderson, P.4    Szczepaniak, L.S.5
  • 25
    • 0037036456 scopus 로고    scopus 로고
    • Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes
    • Clyne CD, Speed CJ, Zhou J, Simpson ER. (2002) Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes. J Biol Chem 277:20591-20597.
    • (2002) J Biol Chem , vol.277 , pp. 20591-20597
    • Clyne, C.D.1    Speed, C.J.2    Zhou, J.3    Simpson, E.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.