Systemic inflammation promotes lung metastasis via E-selectin upregulation in mouse breast cancer model

Cancer Biology and Therapy

Volumn 15, Issue 6, 2014, Pages 789-796

  Jiang, Man ^a   Xu, Xiaoya ^a   Bi, Yuli ^a   Xu, Jiying ^a   Qin, Chengyong ^a   Han, Mingyong ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Breast cancer; E selectin; Inflammation; LPS; Lung; Metastasis; Microenvironment

Indexed keywords

CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; LIPOPOLYSACCHARIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INFLAMMATION; LUNG METASTASIS; LUNG PARENCHYMA; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN EXPRESSION; UPREGULATION; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; CANCER TRANSPLANTATION; CELL ADHESION; CELL PROLIFERATION; COCULTURE; EXPERIMENTAL MAMMARY NEOPLASM; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; IMMUNOLOGY; LUNG TUMOR; METABOLISM; PATHOLOGY; PULMONARY ARTERY; SECONDARY; TUMOR CELL LINE; VASCULAR ENDOTHELIUM;

ANIMALS; CELL ADHESION; CELL LINE, TUMOR; CELL PROLIFERATION; COCULTURE TECHNIQUES; E-SELECTIN; ENDOTHELIUM, VASCULAR; FEMALE; GENE EXPRESSION; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; LUNG NEOPLASMS; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE, INBRED BALB C; NEOPLASM TRANSPLANTATION; PULMONARY ARTERY; UP-REGULATION;

EID: 84901720015     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.28552     Document Type: Article

References (47)

1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2013. CA Cancer J Clin 2013; 63:11-30; PMID:23335087; http://dx.doi.org/10.3322/caac.21166
2. DeSantis C, Siegel R, Bandi P, Jemal A. Breast cancer statistics, 2011. CA Cancer J Clin 2011; 61:409-18; PMID:21969133; http://dx.doi.org/10.3322/caac. 20134
3. rd, Vachon CM, Jacobsen EA, Abdala-Valencia H, McGarry MP, Ochkur SI, Protheroe CA, Doyle A, Grant CS, et al. Allergic pulmonary inflammation promotes the recruitment of circulating tumor cells to the lung. Cancer Res 2008; 68:8582-9; PMID:18922934; http://dx.doi.org/10.1158/0008-5472.CAN-08-1673
4. Cabodi S, Taverna D. Interfering with inflammation: a new strategy to block breast cancer self-renewal and progression? Breast Cancer Res 2010; 12:305; PMID:20459595; http://dx.doi.org/10.1186/bcr2563
5. St Hill CA, Krieser K, Farooqui M. Neutrophil interactions with sialyl Lewis X on human nonsmall cell lung carcinoma cells regulate invasive behavior. Cancer 2011; 117:4493-505; PMID:21437888; http://dx.doi.org/10.1002/cncr.26059
6. Langley RR, Fidler IJ. The seed and soil hypothesis revisited - the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer 2011; 128:2527-35; PMID:21365651; http://dx.doi.org/10.1002/ijc.26031
7. Albulescu R, Codrici E, Popescu ID, Mihai S, Necula LG, Petrescu D, Teodoru M, Tanase CP. Cytokine patterns in brain tumour progression. Mediators Inflamm 2013; 2013:979748; PMID:23864770; http://dx.doi.org/10.1155/2013/979748
8. Jubeli E, Moine L, Vergnaud-Gauduchon J, Barratt G. E-selectin as a target for drug delivery and molecular imaging. J Control Release 2012; 158:194-206; PMID:21983284; http://dx.doi.org/10.1016/j.jconrel.2011.09.084
9. Witz IP. The selectin-selectin ligand axis in tumor progression. Cancer Metastasis Rev 2008; 27:19-30; PMID:18180878; http://dx.doi.org/10.1007/s10555- 007-9101-z
10. Lee CG, Link H, Baluk P, Homer RJ, Chapoval S, Bhandari V, Kang MJ, Cohn L, Kim YK, McDonald DM, et al. Vascular endothelial growth factor (VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. Nat Med 2004; 10:1095-103; PMID:15378055; http://dx.doi.org/10.1038/nm1105
11. Kansas GS. Selectins and their ligands: current concepts and controversies. Blood 1996; 88:3259-87; PMID:8896391
12. Vestweber D, Blanks JE. Mechanisms that regulate the function of the selectins and their ligands. Physiol Rev 1999; 79:181-213; PMID:9922371
13. Stannard AK, Khurana R, Evans IM, Sofra V, Holmes DI, Zachary I. Vascular endothelial growth factor synergistically enhances induction of E-selectin by tumor necrosis factor-alpha. Arterioscler Thromb Vasc Biol 2007; 27:494-502; PMID:17170373; http://dx.doi.org/10.1161/01.ATV.0000255309.38699.6c
14. Gout S, Tremblay PL, Huot J. Selectins and selectin ligands in extravasation of cancer cells and organ selectivity of metastasis. Clin Exp Metastasis 2008; 25:335-44; PMID:17891461; http://dx.doi.org/10.1007/s10585-007- 9096-4
15. Lichtenberger BM, Tan PK, Niederleithner H, Ferrara N, Petzelbauer P, Sibilia M. Autocrine VEGF signaling synergizes with EGFR in tumor cells to promote epithelial cancer development. Cell 2010; 140:268-79; PMID:20141840; http://dx.doi.org/10.1016/j.cell.2009.12.046
16. Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, Viale A, Olshen AB, Gerald WL, Massagué J. Genes that mediate breast cancer metastasis to lung. Nature 2005; 436:518-24; PMID:16049480; http://dx.doi.org/10.1038/ nature03799
17. Das Roy L, Pathangey LB, Tinder TL, Schettini JL, Gruber HE, Mukherjee P. Breast-cancer-associated metastasis is significantly increased in a model of autoimmune arthritis. Breast Cancer Res 2009; 11:R56; PMID:19643025; http://dx.doi.org/10.1186/bcr2345
18. Han M, Xu J, Bi Y, Jiang M, Xu X, Liu Q, Jia J. Primary tumor regulates the pulmonary microenvironment in melanoma carcinoma model and facilitates lung metastasis. J Cancer Res Clin Oncol 2013; 139:57-65; PMID:22903384; http://dx.doi.org/10.1007/s00432-012-1299-7
19. Murdoch C, Muthana M, Coffelt SB, Lewis CE. The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer 2008; 8:618-31; PMID:18633355; http://dx.doi.org/10.1038/nrc2444
20. Lu H, Ouyang W, Huang C. Inflammation, a key event in cancer development. Mol Cancer Res 2006; 4:221-33; PMID:16603636; http://dx.doi.org/10.1158/1541- 7786.MCR-05-0261
21. Nguyen DX, Bos PD, Massagué J. Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 2009; 9:274-84; PMID:19308067; http://dx.doi.org/10.1038/nrc2622
22. Mantovani A, Locati M. Tumor-associated macrophages as a paradigm of macrophage plasticity, diversity, and polarization: lessons and open questions. Arterioscler Thromb Vasc Biol 2013; 33:1478-83; PMID:23766387; http://dx.doi.org/10.1161/ATVBAHA.113.300168
23. Grote K, Schütt H, Schieffer B. Toll-like receptors in angiogenesis. ScientificWorldJournal 2011; 11:981-91; PMID:21516292; http://dx.doi.org/10. 1100/tsw.2011.92
24. Alitalo A, Detmar M. Interaction of tumor cells and lymphatic vessels in cancer progression. Oncogene 2012; 31:4499-508; PMID:22179834; http://dx.doi.org/10.1038/onc.2011.602
25. Nguyen DX, Bos PD, Massagué J. Metastasis: from dissemination to organ-specific colonization. Nat Rev Cancer 2009; 9:274-84; PMID:19308067; http://dx.doi.org/10.1038/nrc2622
26. Mantovani A, Allavena P, Sica A, Balkwill F. Cancer-related inflammation. Nature 2008; 454:436-44; PMID:18650914; http://dx.doi.org/10.1038/nature07205
27. He W, Liu Q, Wang L, Chen W, Li N, Cao X. TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance. Mol Immunol 2007; 44:2850-9; PMID:17328955; http://dx.doi.org/10.1016/j.molimm.2007.01.022
28. Wang L, Liu Q, Sun Q, Zhang C, Chen T, Cao X. TLR4 signaling in cancer cells promotes chemoattraction of immature dendritic cells via autocrine CCL20. Biochem Biophys Res Commun 2008; 366:852-6; PMID:18083111; http://dx.doi.org/10. 1016/j.bbrc.2007.12.030
29. Bevilacqua MP, Stengelin S, Gimbrone MA Jr., Seed B. Endothelial leukocyte adhesion molecule 1: an inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 1989; 243:1160-5; PMID:2466335; http://dx.doi.org/10.1126/science.2466335
30. Wong D, Dorovini-Zis K. Regualtion by cytokines and lipopolysaccharide of E-selectin expression by human brain microvessel endothelial cells in primary culture. J Neuropathol Exp Neurol 1996; 55:225-35; PMID:8786381; http://dx.doi.org/10.1097/00005072-199602000-00011
31. Fukami A, Iijima K, Hayashi M, Komiyama K, Omura S. Macrosphelide B suppressed metastasis through inhibition of adhesion of sLe(x)/E-selectin molecules. Biochem Biophys Res Commun 2002; 291:1065-70; PMID:11866473; http://dx.doi.org/10.1006/bbrc.2002.6572
32. Khatib AM, Auguste P, Fallavollita L, Wang N, Samani A, Kontogiannea M, Meterissian S, Brodt P. Characterization of the host proinflammatory response to tumor cells during the initial stages of liver metastasis. Am J Pathol 2005; 167:749-59; PMID:16127154; http://dx.doi.org/10.1016/S0002-9440(10)62048-2
33. St Hill CA. Interactions between endothelial selectins and cancer cells regulate metastasis. Front Biosci (Landmark Ed) 2011; 16:3233-51; PMID:21622232; http://dx.doi.org/10.2741/3909
34. Banks RE, Gearing AJ, Hemingway IK, Norfolk DR, Perren TJ, Selby PJ. Circulating intercellular adhesion molecule-1 (ICAM-1), E-selectin and vascular cell adhesion molecule-1 (VCAM-1) in human malignancies. Br J Cancer 1993; 68:122-4; PMID:7686390; http://dx.doi.org/10.1038/bjc.1993.298
35. Velikova G, Banks RE, Gearing A, Hemingway I, Forbes MA, Preston SR, Hall NR, Jones M, Wyatt J, Miller K, et al. Serum concentrations of soluble adhesion molecules in patients with colorectal cancer. Br J Cancer 1998; 77:1857-63; PMID:9667659; http://dx.doi.org/10.1038/bjc.1998.309
36. O'Hanlon DM, Fitzsimons H, Lynch J, Tormey S, Malone C, Given HF. Soluble adhesion molecules (E-selectin, ICAM-1 and VCAM-1) in breast carcinoma. Eur J Cancer 2002; 38:2252-7; PMID:12441261; http://dx.doi.org/10.1016/S0959-8049(02) 00218-6
37. Gassmann P, Hemping-Bovenkerk A, Mees ST, Haier J. Metastatic tumor cell arrest in the liver-lumen occlusion and specific adhesion are not exclusive. Int J Colorectal Dis 2009; 24:851-8; PMID:19319542; http://dx.doi.org/10.1007/ s00384-009-0694-2
38. Sheen-Chen SM, Eng HL, Huang CC, Chen WJ. Serum levels of soluble E-selectin in women with breast cancer. Br J Surg 2004; 91:1578-81; PMID:15386328; http://dx.doi.org/10.1002/bjs.4513
39. Khatib AM, Kontogiannea M, Fallavollita L, Jamison B, Meterissian S, Brodt P. Rapid induction of cytokine and E-selectin expression in the liver in response to metastatic tumor cells. Cancer Res 1999; 59:1356-61; PMID:10096570
40. Leeuwenberg JF, Smeets EF, Neefjes JJ, Shaffer MA, Cinek T, Jeunhomme TM, Ahern TJ, Buurman WA. E-selectin and intercellular adhesion molecule-1 are released by activated human endothelial cells in vitro. Immunology 1992; 77:543-9; PMID:1283598
41. Hiratsuka S, Goel S, Kamoun WS, Maru Y, Fukumura D, Duda DG, Jain RK. Endothelial focal adhesion kinase mediates cancer cell homing to discrete regions of the lungs via E-selectin up-regulation. Proc Natl Acad Sci U S A 2011; 108:3725-30; PMID:21321210; http://dx.doi.org/10.1073/pnas.1100446108
42. Barthel SR, Wiese GK, Cho J, Opperman MJ, Hays DL, Siddiqui J, Pienta KJ, Furie B, Dimitroff CJ. Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking. Proc Natl Acad Sci U S A 2009; 106:19491-6; PMID:19889975; http://dx.doi.org/10.1073/pnas.0906074106
43. Tremblay PL, Huot J, Auger FA. Mechanisms by which E-selectin regulates diapedesis of colon cancer cells under flow conditions. Cancer Res 2008; 68:5167-76; PMID:18593916; http://dx.doi.org/10.1158/0008-5472.CAN-08-1229
44. Kobayashi K, Matsumoto S, Morishima T, Kawabe T, Okamoto T. Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Res 2000; 60:3978-84; PMID:10919677
45. Wang X, Grace PM, Pham MN, Cheng K, Strand KA, Smith C, Li J, Watkins LR, Yin H. Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain. FASEB J 2013; 27:2713-22; PMID:23568774; http://dx.doi.org/10.1096/fj.12-222992
46. Kim JE, Lee S, Han KS, Kim HK. Aurintricarboxylic acid inhibits the nuclear factor-κB-dependent expression of intercellular cell adhesion molecule-1 and endothelial cell selectin on activated human endothelial cells. Blood Coagul Fibrinolysis 2011; 22:132-9; PMID:21245742; http://dx.doi.org/10. 1097/MBC.0b013e32834356b6
47. Chen SF, Fei X, Li SH. A new simple method for isolation of microvascular endothelial cells avoiding both chemical and mechanical injuries. Microvasc Res 1995; 50:119-28; PMID:7476573; http://dx.doi.org/10.1006/mvre.1995.1044