Severity of obstructive sleep apnea is associated with cardiac troponin I concentrations in a community-based sample: Data from the Akershus Sleep Apnea Project

Sleep

Volumn 37, Issue 6, 2014, Pages 1111-1116

  Einvik, Gunnar ^a,b   Rsøjø, Helge ^a,b   Randby, Anna ^a,b   Namtvedt, Silje K ^a,b   Hrubos Strmø, Harald ^a,b   Brynildsen, Jon ^a,b   Somers, Virend K ^c   Omland, Torbjrøn ^a,b  

^a AKERSHUS UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c MAYO CLINIC   (United States)

Author keywords

Akershus Sleep Apnea Project; Obstructive sleep apnea; Polysomnography; Troponin I

Indexed keywords

CHOLESTEROL; CREATININE; TROPONIN I; BIOLOGICAL MARKER;

ADULT; APNEA HYPOPNEA INDEX; ARTICLE; BLOOD SAMPLING; BODY MASS; CARDIAC TROPONIN 1 CLIA KIT; CARDIOVASCULAR RISK; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CREATININE CLEARANCE; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DIET RESTRICTION; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HEART LEFT VENTRICLE HYPERTROPHY; HEART MUSCLE INJURY; HEART RATE; HUMAN; HYPERTENSION; HYPOXEMIA; LIMIT OF DETECTION; MAJOR CLINICAL STUDY; MALE; MEDICAL HISTORY; POLYSOMNOGRAPHY; PRIORITY JOURNAL; SLEEP DISORDERED BREATHING; SLEEP TIME; SMOKING; SYSTOLIC BLOOD PRESSURE; CARDIAC MUSCLE; COMPLICATION; METABOLISM; MIDDLE AGED; PATHOLOGY; PATHOPHYSIOLOGY; SLEEP;

BIOMARKERS; BODY MASS INDEX; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIUM; POLYSOMNOGRAPHY; SLEEP; SLEEP APNEA, OBSTRUCTIVE; TROPONIN I;

EID: 84901709128     PISSN: 01618105     EISSN: 15509109     Source Type: Journal    
DOI: 10.5665/sleep.3772     Document Type: Article

References (36)

1. Jennum P, Riha RL. Epidemiology of sleep apnoea/hypopnoea syndrome and sleep-disordered breathing. Eur Resp J 2009;33:907-14.
2. Somers VK, White DP, Amin R, et al. Sleep Apnea and cardiovascular disease. An American Heart Association/American College of Cardiology Foundation Scientific Statement From the American Heart Association Council for High Blood Pressure Research Professional Education Committee, Council on Clinical Cardiology, Stroke Council, and Council on Cardiovascular Nursing Council. Circulation 2008;118:1080-111.
3. Baguet JP, Barone-Rochette G, Levy P. Left ventricular diastolic dysfunction is linked to severity of obstructive sleep apnoea. Eur Resp J 2010;36:1323-9.
4. Gottlieb DJ, Yenokyan G, Newman AB, et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the sleep heart health study. Circulation 2010;122:352-60.
5. Kohli P, Balachandran JS, Malhotra A. Obstructive sleep apnea and the risk for cardiovascular disease. Curr Atheroscler Rep 2011;13:138-46.
6. Kasai T, Bradley TD. Obstructive sleep apnea and heart failure: pathophysiologic and therapeutic implications. J Am Coll Cardiol 2011;57:119-27.
7. Lurie A. Metabolic disorders associated with obstructive sleep apnea in adults. Adv Cardiol 2011;46:67-138.
8. Sánchez-de-la-Torre M, Campos-Rodriguez F, Barbé F. Obstructive sleep apnoea and cardiovascular disease. Lancet Resp Med 2013;1:61-72.
9. Lurie A. Cardiovascular disorders associated with obstructive sleep apnea. Adv Cardiol 2012;46:197-266.
10. Gami AS, Svatikova A, Wolk R, et al. Cardiac troponin T in obstructive sleep apnea. Chest 2004;125:2097-100. (Pubitemid 38788175)
11. Oktay B, Akbal E, Firat H, Ardic S, Akdemir R, Kizilgun M. Evaluation of the relationship between heart type fatty acid binding protein levels and the risk of cardiac damage in patients with obstructive sleep apnea syndrome. Sleep Breath 2008;12:223-8.
12. Koehnlein T, Schmidt A, Moesenthin M, Dierkes J, Neumann KH, Welte T. Increased cardiac troponin T and C-reactive protein levels in end-stage renal disease are associated with obstructive sleep apnea. Clin Nephrol 2009;71:50-8.
13. Cifci N, Uyar M, Elbek O, Suyur H, Ekinci E. Impact of CPAP treatment on cardiac biomarkers and pro-BNP in obstructive sleep apnea syndrome. Sleep Breath 2010;14:241-4.
14. Colish J, Walker JR, Elmayergi N, et al. Obstructive sleep apnea: Effects of continuous positive airway pressure on cardiac remodeling as assessed by cardiac biomarkers, echocardiography, and cardiac MRI. Chest 2012;141:674-81.
15. Randby A, Namtvedt SK, Einvik G, et al. Obstructive sleep apnea is associated with increased high-sensitivity cardiac troponin T levels. Chest 2012;142:639-46.
16. Inami T, Seino Y, Otsuka T, et al. Links between sleep disordered breathing, coronary atherosclerotic burden, and cardiac biomarkers in patients with stable coronary artery disease. J Cardiol 2012;60:180-6.
17. Yoshihisa A, Suzuki S, Yamaki T, et al. Impact of adaptive servoventilation on cardiovascular function and prognosis in heart failure patients with preserved left ventricular ejection fraction and sleepdisordered breathing. Eur J Heart Fail 2013;15:543-50.
18. Røsjø H, Kravdal G, Høiseth AD, et al. Troponin I measured by a high-sensitivity assay in patients with suspected reversible myocardial ischemia: data from the Akershus Cardiac Examination (ACE) 1 Study. Clin Chem 2012;58:1565-73.
19. Jaffe AS, Vasile VC, Milone M, Saenger AK, Olson KN, Apple FS. Diseased skeletal muscle: a noncardiac source of increased circulating concentrations of cardiac troponin T. J Am Coll Cardiol 2011;58:1819-24.
20. Labugger R, Organ L, Collier C, Atar D, Van Eyk JE. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction. Circulation 2000;102:1221-6.
21. Hrubos-Strøm H, Randby A, Namtvedt SK, et al. A Norwegian population-based study on the risk and prevalence of obstructive sleep apnea: The Akershus Sleep Apnea Project (ASAP). J Sleep Res 2011;20:162-70.
22. Netzer NC, Stoohs RA, Netzer CM, Clark K, Strohl KP. Using the Berlin Questionnaire to identify patients at risk for the sleep apnea syndrome. Ann Intern Med 1999;131:485-91. (Pubitemid 29482391)
23. Rechtshaffen A, Kales A. A manual of standardized terminology and scoring system for sleep stages of human sleep. Los Angeles, CA: University of California at Los Angeles, Brain Information Service/Brain Research Institute, 1968.
24. American Academy of Sleep Medicine. International classification of sleep disorders: diagnostic and coding manual. 2nd ed. Westchester, IL: American Academy of Sleep Medicine, 2005.
25. Apple FS, Ler R, Murakami MM. Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population. Clin Chem 2012;58:1574-81.
26. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron 1976;16:31-41.
27. Sokolow M, Lyon K. The ventricular complex in left ventricular hypertrophy as obtained by unipolar precordial and limb leads. Am J Cardiol 1949;37:161-9.
28. Casale PN, Devereux RB, Kligfield P, et al. Electrocardiographic detection of left ventricular hypertrophy: development and prospective validation of improved criteria. J Am Coll Cardiol 1985;6:572-80. (Pubitemid 16219234)
29. Røysland R, Kravdal G, Høiseth AD, et al. Cardiac troponin T levels and exercise stress testing in patients with suspected coronary artery disease: the Akershus Cardiac Examination (ACE) 1 study. Clin Sci 2012;122:599-606.
30. White HD. Pathobiology of troponin elevations: do elevations occur with myocardial ischemia as well as necrosis? J Am Coll Cardiol 2011;57:2406-8.
31. Omland T, Pfeffer MA, Solomon SD, et al. Prognostic value of cardiac troponin I measured with a highly sensitive assay in patients with stable coronary artery disease. J Am Coll Cardiol 2013;61:1240-9.
32. Turer AT, Addo TA, Martin JL, et al. Myocardial ischemia induced by rapid atrial pacing causes troponin T release detectable by a highly sensitive assay: insights from a coronary sinus sampling study. J Am Coll Cardiol 2011;57:2398-405.
33. Querejeta Roca G, Redline S, Punjabi N, et al. Sleep apnea is associated with subclinical myocardial injury in the community: the ARIC-SHHS study. Am J Respir Crit Care Med 2013;188:1460-5
34. Omland T, de Lemos JA, Sabatine MS, et al. A sensitive cardiac troponin T assay in stable coronary artery disease. N Engl J Med 2009;361:2538-47.
35. de Lemos JA, Drazner MH, Omland T, et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA 2010;304:2503-12.
36. Namtvedt SK, Hisdal J, Randby A, et al. Impaired endothelial function in persons with obstructive sleep apnoea: impact of obesity. Heart 2013;99:30-4.