An activin receptor IIA ligand trap promotes erythropoiesis resulting in a rapid induction of red blood cells and haemoglobin

British Journal of Haematology

Volumn 165, Issue 6, 2014, Pages 870-882

  Carrancio, Soraya ^a   Markovics, Jennifer ^a   Wong, Piu ^a   Leisten, Jim ^a   Castiglioni, Paola ^a   Groza, Matthew C ^a   Raymon, Heather K ^a   Heise, Carla ^a   Daniel, Tom ^a   Chopra, Rajesh ^a   Sung, Victoria ^a  

^a CELGENE CORPORATION   (United States)

Author keywords

Activin receptor IIA inhibition; Erythropoiesis; Haemoglobin

Indexed keywords

ACTIVIN A; ACTIVIN RECEPTOR 2; ACTIVIN RECEPTOR IIA; ERYTHROPOIETIN; GROWTH DIFFERENTIATION FACTOR; GROWTH DIFFERENTIATION FACTOR 11; HEMOGLOBIN; PROTEIN INHIBITOR; RAP 011; SOTATERCEPT; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG;

ACCESSORY CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BURST FORMING UNIT E; CELL EXPANSION; COCULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ERYTHROCYTE COUNT; ERYTHROID PRECURSOR CELL; ERYTHROPOIESIS; FEMALE; HEMATOCRIT; HUMAN; HUMAN CELL; IN VITRO STUDY; INHIBITION KINETICS; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL;

ACTIVIN RECEPTOR IIA INHIBITION; ERYTHROPOIESIS; HAEMOGLOBIN;

ACTIVIN RECEPTORS, TYPE II; ANIMALS; BONE MARROW CELLS; CELLULAR MICROENVIRONMENT; COLONY-FORMING UNITS ASSAY; ERYTHROCYTE INDICES; ERYTHROCYTES; ERYTHROID PRECURSOR CELLS; ERYTHROPOIESIS; ERYTHROPOIETIN; FEMALE; HEMOGLOBINS; HUMANS; LIGANDS; MICE; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA;

EID: 84901690058     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/bjh.12838     Document Type: Article

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