메뉴 건너뛰기




Volumn 145, Issue 2, 2014, Pages 339-348

Epithelial mesenchymal transition in early invasive breast cancer: An immunohistochemical and reverse phase protein array study

Author keywords

Cadherin switch; EMT; Immunohistochemistry; Reverse Phase Protein Array; RPPA

Indexed keywords

CADHERIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FORMALDEHYDE; NERVE CELL ADHESION MOLECULE; PARAFFIN; PROTEIN KINASE B; PROTEIN PIK3CA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR MARKER; UNCLASSIFIED DRUG; UVOMORULIN; CDH2 PROTEIN, HUMAN; ERBB2 PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; PHOSPHATIDYLINOSITOL 3 KINASE; PIK3CA PROTEIN, HUMAN;

EID: 84901680245     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-014-2927-5     Document Type: Article
Times cited : (53)

References (41)
  • 1
    • 33244463813 scopus 로고    scopus 로고
    • Complex networks orchestrate epithelial-mesenchymal transitions
    • DOI 10.1038/nrm1835, PII NRM1835
    • Thiery JP, Sleeman JP (2006) Complex networks orchestrate epithelial-mesenchymal transitions. Nat Rev Mol Cell Biol 7(2):131-142 (Pubitemid 43278296)
    • (2006) Nature Reviews Molecular Cell Biology , vol.7 , Issue.2 , pp. 131-142
    • Thiery, J.P.1    Sleeman, J.P.2
  • 2
    • 34548175512 scopus 로고    scopus 로고
    • Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression
    • DOI 10.1111/j.1349-7006.2007.00550.x
    • Moustakas A, Heldin CH (2007) Signaling networks guiding epithelial-mesenchymal transitions during embryogenesis and cancer progression. Cancer Sci 98(10):1512-1520 (Pubitemid 47308444)
    • (2007) Cancer Science , vol.98 , Issue.10 , pp. 1512-1520
    • Moustakas, A.1    Heldin, C.-H.2
  • 3
    • 0036595629 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in tumour progression
    • 1:CAS:528:DC%2BD38Xksl2ltr8%3D 12189386 10.1038/nrc822
    • Thiery JP (2002) Epithelial-mesenchymal transitions in tumour progression. Nat Rev Cancer 2(6):442-454
    • (2002) Nat Rev Cancer , vol.2 , Issue.6 , pp. 442-454
    • Thiery, J.P.1
  • 4
    • 75649151387 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transition in cancer development and its clinical significance
    • 1:CAS:528:DC%2BC3cXivFeqtrY%3D 19961486 10.1111/j.1349-7006.2009.01419.x
    • Iwatsuki M et al (2010) Epithelial-mesenchymal transition in cancer development and its clinical significance. Cancer Sci 101(2):293-299
    • (2010) Cancer Sci , vol.101 , Issue.2 , pp. 293-299
    • Iwatsuki, M.1
  • 5
    • 77954860408 scopus 로고    scopus 로고
    • The pathology of EMT in mouse mammary tumorigenesis
    • 2886116 20521088 10.1007/s10911-010-9184-y
    • Cardiff R (2010) The pathology of EMT in mouse mammary tumorigenesis. J Mammary Gland Biol Neoplasia 15(2):225-233
    • (2010) J Mammary Gland Biol Neoplasia , vol.15 , Issue.2 , pp. 225-233
    • Cardiff, R.1
  • 6
    • 77949794643 scopus 로고    scopus 로고
    • Epithelial to mesenchymal transition and breast cancer
    • 2815537 19909494 10.1186/bcr2416
    • Tomaskovic-Crook E, Thompson EW, Thiery JP (2009) Epithelial to mesenchymal transition and breast cancer. Breast Cancer Res 11(6):213
    • (2009) Breast Cancer Res , vol.11 , Issue.6 , pp. 213
    • Tomaskovic-Crook, E.1    Thompson, E.W.2    Thiery, J.P.3
  • 7
    • 63049123066 scopus 로고    scopus 로고
    • Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits
    • 1:CAS:528:DC%2BD1MXis1Chtb0%3D 19262571 10.1038/nrc2620
    • Polyak K, Weinberg RA (2009) Transitions between epithelial and mesenchymal states: Acquisition of malignant and stem cell traits. Nat Rev Cancer 9(4):265-273
    • (2009) Nat Rev Cancer , vol.9 , Issue.4 , pp. 265-273
    • Polyak, K.1    Weinberg, R.A.2
  • 8
    • 47549098328 scopus 로고    scopus 로고
    • New insights of epithelial-mesenchymal transition in cancer metastasis
    • DOI 10.1111/j.1745-7270.2008.00443.x
    • Wu Y, Zhou BP (2008) New insights of epithelial-mesenchymal transition in cancer metastasis. Acta Biochim Biophys Sin (Shanghai) 40(7):643-650 (Pubitemid 352009085)
    • (2008) Acta Biochimica et Biophysica Sinica , vol.40 , Issue.7 , pp. 643-650
    • Wu, Y.1    Zhou, B.P.2
  • 9
    • 0038745381 scopus 로고    scopus 로고
    • The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis
    • Xue C et al (2003) The gatekeeper effect of epithelial-mesenchymal transition regulates the frequency of breast cancer metastasis. Cancer Res 63(12):3386-3394 (Pubitemid 36735899)
    • (2003) Cancer Research , vol.63 , Issue.12 , pp. 3386-3394
    • Xue, C.1    Plieth, D.2    Venkov, C.3    Xu, C.4    Neilson, E.G.5
  • 10
    • 70449526719 scopus 로고    scopus 로고
    • Localized and reversible TGF[beta] signalling switches breast cancer cells from cohesive to single cell motility
    • 1:CAS:528:DC%2BD1MXhtlCnu7rN 2773241 19838175 10.1038/ncb1973
    • Giampieri S et al (2009) Localized and reversible TGF[beta] signalling switches breast cancer cells from cohesive to single cell motility. Nat Cell Biol 11(11):1287-1296
    • (2009) Nat Cell Biol , vol.11 , Issue.11 , pp. 1287-1296
    • Giampieri, S.1
  • 11
    • 22244473343 scopus 로고    scopus 로고
    • The fallacy of epithelial mesenchymal transition in neoplasia
    • DOI 10.1158/0008-5472.CAN-05-0699
    • Tarin D (2005) The fallacy of epithelial mesenchymal transition in neoplasia. Cancer Res 65(14):5996-6001 (Pubitemid 40994379)
    • (2005) Cancer Research , vol.65 , Issue.14 , pp. 5996-6000
    • Tarin, D.1
  • 12
    • 33645758275 scopus 로고    scopus 로고
    • Tumor invasion in the absence of epithelial-mesenchymal transition: Podoplanin-mediated remodeling of the actin cytoskeleton
    • 1:CAS:528:DC%2BD28XjvFeiurw%3D 16616332 10.1016/j.ccr.2006.03.010
    • Wicki A et al (2006) Tumor invasion in the absence of epithelial-mesenchymal transition: podoplanin-mediated remodeling of the actin cytoskeleton. Cancer Cell 9(4):261-272
    • (2006) Cancer Cell , vol.9 , Issue.4 , pp. 261-272
    • Wicki, A.1
  • 13
    • 34447272058 scopus 로고    scopus 로고
    • Mechanisms of metastasis: Epithelial-to-mesenchymal transition and contribution of tumor microenvironment
    • DOI 10.1002/jcb.21215
    • Tse JC, Kalluri R (2007) Mechanisms of metastasis: epithelial-to- mesenchymal transition and contribution of tumor microenvironment. J Cell Biochem 101(4):816-829 (Pubitemid 47040864)
    • (2007) Journal of Cellular Biochemistry , vol.101 , Issue.4 , pp. 816-829
    • Tse, J.C.1    Kalluri, R.2
  • 14
    • 78649987710 scopus 로고    scopus 로고
    • Transforming growth factor-beta-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression
    • 1:CAS:528:DC%2BC3cXhtVyqsL7O 3076082 20802523 10.1038/onc.2010.377
    • Wendt MK, Smith JA, Schiemann WP (2010) Transforming growth factor-beta-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression. Oncogene 29(49):6485-6498
    • (2010) Oncogene , vol.29 , Issue.49 , pp. 6485-6498
    • Wendt, M.K.1    Smith, J.A.2    Schiemann, W.P.3
  • 16
    • 78650510746 scopus 로고    scopus 로고
    • Emergence of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin axis in transforming growth factor-beta-induced epithelial-mesenchymal transition
    • 1:CAS:528:DC%2BC3cXhsFOgtb%2FM 21041997 10.1159/000320172
    • Lamouille S, Derynck R (2011) Emergence of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin axis in transforming growth factor-beta-induced epithelial-mesenchymal transition. Cells Tissues Organs 193(1-2):8-22
    • (2011) Cells Tissues Organs , vol.193 , Issue.1-2 , pp. 8-22
    • Lamouille, S.1    Derynck, R.2
  • 17
    • 66749192716 scopus 로고    scopus 로고
    • C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer
    • 1:CAS:528:DC%2BD1MXls1Ort70%3D 19214987 10.1002/path.2508
    • Albasri A et al (2009) C-terminal Tensin-like (CTEN) is an oncogene which alters cell motility possibly through repression of E-cadherin in colorectal cancer. J Pathol 218(1):57-65
    • (2009) J Pathol , vol.218 , Issue.1 , pp. 57-65
    • Albasri, A.1
  • 18
    • 5444230567 scopus 로고    scopus 로고
    • Transcriptional regulation of cadherins during development and carcinogenesis
    • DOI 10.1387/ijdb.041794hp, Invasion in Cancer and Embryonic Development
    • Peinado H, Portillo F, Cano A (2004) Transcriptional regulation of cadherins during development and carcinogenesis. Int J Dev Biol 48(5-6):365-375 (Pubitemid 39360388)
    • (2004) International Journal of Developmental Biology , vol.48 , Issue.5-6 , pp. 365-375
    • Peinado, H.1    Portillo, F.2    Cano, A.3
  • 20
    • 35848946387 scopus 로고    scopus 로고
    • Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: An exception to the norm
    • DOI 10.1002/jcp.21240
    • Ahmed N, Thompson EW, Quinn MA (2007) Epithelial-mesenchymal interconversions in normal ovarian surface epithelium and ovarian carcinomas: An exception to the norm. J Cell Physiol 213(3):581-588 (Pubitemid 350058249)
    • (2007) Journal of Cellular Physiology , vol.213 , Issue.3 , pp. 581-588
    • Ahmed, N.1    Thompson, E.W.2    Quinn, M.A.3
  • 21
    • 77956811470 scopus 로고    scopus 로고
    • Tumor-stromal interactions influence radiation sensitivity in epithelial-versus mesenchymal-like prostate cancer cells
    • 10.1155/2010/232831 2926670 20798867
    • Josson S et al (2010) Tumor-stromal interactions influence radiation sensitivity in epithelial-versus mesenchymal-like prostate cancer cells. J Oncol. doi: 10.1155/2010/232831
    • (2010) J Oncol
    • Josson, S.1
  • 22
    • 79952845386 scopus 로고    scopus 로고
    • The role of B-RAF mutations in melanoma and the induction of EMT via dysregulation of the NF-kappaB/Snail/RKIP/PTEN circuit
    • 1:CAS:528:DC%2BC3cXhtVyjs7vF 2933925 20827424 10.1177/1947601910373795
    • Lin K et al (2010) The role of B-RAF mutations in melanoma and the induction of EMT via dysregulation of the NF-kappaB/Snail/RKIP/PTEN circuit. Genes Cancer 1(5):409-420
    • (2010) Genes Cancer , vol.1 , Issue.5 , pp. 409-420
    • Lin, K.1
  • 24
    • 58749095653 scopus 로고    scopus 로고
    • Reverse-phase protein lysate microarrays for cell signaling analysis
    • 18974738 10.1038/nprot.2008.179
    • Spurrier B, Ramalingam S, Nishizuka S (2008) Reverse-phase protein lysate microarrays for cell signaling analysis. Nat Protoc 3(11):1796-1808
    • (2008) Nat Protoc , vol.3 , Issue.11 , pp. 1796-1808
    • Spurrier, B.1    Ramalingam, S.2    Nishizuka, S.3
  • 26
    • 77953657140 scopus 로고    scopus 로고
    • Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification
    • 2908584 20569466 10.1186/1477-5956-8-36
    • Brase JC et al (2010) Increasing the sensitivity of reverse phase protein arrays by antibody-mediated signal amplification. Proteome Sci 8:36
    • (2010) Proteome Sci , vol.8 , pp. 36
    • Brase, J.C.1
  • 27
    • 22244449596 scopus 로고    scopus 로고
    • High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses
    • DOI 10.1002/ijc.21004
    • Abd El-Rehim DM et al (2005) High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int J Cancer 116(3):340-350 (Pubitemid 40993329)
    • (2005) International Journal of Cancer , vol.116 , Issue.3 , pp. 340-350
    • Abd El-Rehim, D.M.1    Ball, G.2    Finder, S.E.3    Rakha, E.4    Paish, C.5    Robertson, J.F.R.6    Macmillan, D.7    Blamey, R.W.8    Ellis, I.O.9
  • 28
    • 65249104546 scopus 로고    scopus 로고
    • Triple-negative breast cancer: Distinguishing between basal and nonbasal subtypes
    • 1:CAS:528:DC%2BD1MXjvVWltbs%3D 19318481 10.1158/1078-0432.CCR-08-2132
    • Rakha EA et al (2009) Triple-negative breast cancer: distinguishing between basal and nonbasal subtypes. Clin Cancer Res 15(7):2302-2310
    • (2009) Clin Cancer Res , vol.15 , Issue.7 , pp. 2302-2310
    • Rakha, E.A.1
  • 29
    • 77449119497 scopus 로고    scopus 로고
    • Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer
    • 1:CAS:528:DC%2BC3cXhtl2it70%3D 19711345
    • Aleskandarany MA et al (2010) Growth fraction as a predictor of response to chemotherapy in node-negative breast cancer. Int J Cancer 126(7):1761-1769
    • (2010) Int J Cancer , vol.126 , Issue.7 , pp. 1761-1769
    • Aleskandarany, M.A.1
  • 30
    • 74949116469 scopus 로고    scopus 로고
    • Significance of twist expression and its association with E-cadherin in esophageal squamous cell carcinoma
    • 2808309 20025748 10.1186/1756-9966-28-158
    • Sasaki K et al (2009) Significance of twist expression and its association with E-cadherin in esophageal squamous cell carcinoma. J Exp Clin Cancer Res 28:158
    • (2009) J Exp Clin Cancer Res , vol.28 , pp. 158
    • Sasaki, K.1
  • 31
    • 77955471173 scopus 로고    scopus 로고
    • Cadherin switching and bladder cancer
    • Bryan RT, Tselepis C (2010) Cadherin switching and bladder cancer. J Urol 184(2):423-431
    • (2010) J Urol , vol.184 , Issue.2 , pp. 423-431
    • Bryan, R.T.1    Tselepis, C.2
  • 32
    • 77952902430 scopus 로고    scopus 로고
    • Mechanisms of motility in metastasizing cells
    • Yilmaz M, Christofori G (2010) Mechanisms of motility in metastasizing cells. Mol Cancer Res 8(5):629-642
    • (2010) Mol Cancer Res , vol.8 , Issue.5 , pp. 629-642
    • Yilmaz, M.1    Christofori, G.2
  • 33
    • 0022358182 scopus 로고
    • Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies
    • McCarty KS Jr et al (1985) Estrogen receptor analyses. Correlation of biochemical and immunohistochemical methods using monoclonal antireceptor antibodies. Arch Pathol Lab Med 109(8):716-721 (Pubitemid 16237466)
    • (1985) Archives of Pathology and Laboratory Medicine , vol.109 , Issue.8 , pp. 716-721
    • McCarty Jr., K.S.1    Miller, L.S.2    Cox, E.B.3
  • 34
    • 62849124399 scopus 로고    scopus 로고
    • Development and validation of a novel protein extraction methodology for quantitation of protein expression in formalin-fixed paraffin-embedded tissues using western blotting
    • 1:CAS:528:DC%2BD1MXjvFOmu7Y%3D 19156775 10.1002/path.2504
    • Nirmalan NJ et al (2009) Development and validation of a novel protein extraction methodology for quantitation of protein expression in formalin-fixed paraffin-embedded tissues using western blotting. J Pathol 217(4):497-506
    • (2009) J Pathol , vol.217 , Issue.4 , pp. 497-506
    • Nirmalan, N.J.1
  • 36
    • 34247269026 scopus 로고    scopus 로고
    • Genetic determinants of cancer metastasis
    • DOI 10.1038/nrg2101, PII NRG2101
    • Nguyen DX, Massague J (2007) Genetic determinants of cancer metastasis. Nat Rev Genet 8(5):341-352 (Pubitemid 46625811)
    • (2007) Nature Reviews Genetics , vol.8 , Issue.5 , pp. 341-352
    • Nguyen, D.X.1    Massague, J.2
  • 37
    • 33847133038 scopus 로고    scopus 로고
    • Molecular and morphologic distinctions between infiltrating ductal and lobular carcinoma of the breast
    • DOI 10.1111/j.1524-4741.2007.00393.x
    • Yoder BJ, Wilkinson EJ, Massoll NA (2007) Molecular and morphologic distinctions between infiltrating ductal and lobular carcinoma of the breast. Breast J 13(2):172-179 (Pubitemid 46280603)
    • (2007) Breast Journal , vol.13 , Issue.2 , pp. 172-179
    • Yoder, B.J.1    Wilkinson, E.J.2    Massoll, N.A.3
  • 38
    • 18444398846 scopus 로고    scopus 로고
    • Pathology reporting of breast disease: A joint document incorporating the third edition of the NHS Breast Screening Programme's Guidelines for pathology reporting in breast cancer screening and the second edition of the Royal College of Pathologists' minimum dataset for breast cancer histopathology
    • Royal College of Pathologists, London
    • Ellis IO et al (2005) Pathology reporting of breast disease: A joint document incorporating the third edition of the NHS Breast Screening Programme's Guidelines for pathology reporting in breast cancer screening and the second edition of the Royal College of Pathologists' minimum dataset for breast cancer histopathology. In: NHS Cancer Screening Programmes, Royal College of Pathologists, London
    • (2005) NHS Cancer Screening Programmes
    • Ellis, I.O.1
  • 39
    • 77957559346 scopus 로고    scopus 로고
    • Histological features of medullary carcinoma and prognosis in triple-negative basal-like carcinomas of the breast
    • 1:CAS:528:DC%2BC3cXht1emtLfE 20581807 10.1038/modpathol.2010.123
    • Marginean F et al (2010) Histological features of medullary carcinoma and prognosis in triple-negative basal-like carcinomas of the breast. Mod Pathol 23(10):1357-1363
    • (2010) Mod Pathol , vol.23 , Issue.10 , pp. 1357-1363
    • Marginean, F.1
  • 40
    • 84901656240 scopus 로고    scopus 로고
    • Epithelial mesenchymal transition in invasive breast carcinoma: Molecular pathways and relation to molecular subtypes
    • 10.1002/path.2770
    • Aleskandarany M et al (2010) Epithelial mesenchymal transition in invasive breast carcinoma: molecular pathways and relation to molecular subtypes. J Pathol 222(S1):S1-S51
    • (2010) J Pathol , vol.222 , Issue.S1
    • Aleskandarany, M.1
  • 41
    • 43549126870 scopus 로고    scopus 로고
    • Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype
    • DOI 10.1136/jcp.2007.053991
    • Mahler-Araujo B et al (2008) Reduction of E-cadherin expression is associated with non-lobular breast carcinomas of basal-like and triple negative phenotype. J Clin Pathol 61(5):615-620 (Pubitemid 351678214)
    • (2008) Journal of Clinical Pathology , vol.61 , Issue.5 , pp. 615-620
    • Mahler-Araujo, B.1    Savage, K.2    Parry, S.3    Reis-Filho, J.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.