Functional properties of bone marrow-derived MSC-based engineered cartilage are unstable with very long-term in vitro culture

Journal of Biomechanics

Volumn 47, Issue 9, 2014, Pages 2173-2182

  Farrell, Megan J ^a,b   Fisher, Matthew B ^a   Huang, Alice H ^a,b   Shin, John I ^a   Farrell, Kimberly M ^a   Mauck, Robert L ^a,b  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cartilage; Chondrogenesis; Mechanical properties; Mesenchymal stem cells; Three dimensional culture

Indexed keywords

BIOMECHANICS; BODY FLUIDS; CARTILAGE; FLOWCHARTING; HYALURONIC ACID; MECHANICAL PROPERTIES; REPAIR; STEM CELLS; TISSUE;

CHONDROGENESIS; COMPRESSIVE MECHANICAL PROPERTIES; ENGINEERED CARTILAGE; FUNCTIONAL PROPERTIES; LONG TERM STABILITY; MESENCHYMAL STEM CELL; THREE-DIMENSIONAL CULTURE; TISSUE ENGINEERED CARTILAGE CONSTRUCTS;

CELL CULTURE;

GLYCOSAMINOGLYCAN; HYALURONIC ACID; TISSUE SCAFFOLD; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; CARTILAGE; CARTILAGE CELL; CELL CULTURE; CELL ENCAPSULATION; CELL VIABILITY; CHONDROGENESIS; COMPRESSIVE MECHANICAL PROPERTY; CONTROLLED STUDY; COW; HYDROGEL; IN VITRO STUDY; MESENCHYMAL STEM CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; THREE DIMENSIONAL CULTURE; TISSUE ENGINEERING;

CARTILAGE; CHONDROGENESIS; MECHANICAL PROPERTIES; MESENCHYMAL STEM CELLS; THREE-DIMENSIONAL CULTURE;

ANIMALS; BONE MARROW CELLS; CARTILAGE; CATTLE; CELL SURVIVAL; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; FEMUR; GLYCOSAMINOGLYCANS; HYDROGELS; MESENCHYMAL STROMAL CELLS; SEPHAROSE; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84901634781     PISSN: 00219290     EISSN: 18732380     Source Type: Journal    
DOI: 10.1016/j.jbiomech.2013.10.030     Document Type: Article

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