Dairy cows produce cytokine and cytotoxic T cell responses following vaccination with an antigenic fraction from Streptococcus uberis

Veterinary Immunology and Immunopathology

Volumn 160, Issue 1-2, 2014, Pages 51-60

  Neil Wedlock, D ^a   Buddle, Bryce M ^a   Williamson, John ^b   Lacy Hulbert, S Jane ^b   Turner, Sally Anne ^b   Subharat, Supatsak ^a   Heiser, Axel ^a  

^a AGRESEARCH GRASSLANDS   (New Zealand)

^b DAIRYNZ   (New Zealand)

Author keywords

Cow; Mastitis; Streptococcus uberis; Vaccine

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; STREPTOCOCCUS ANTIGEN; STREPTOCOCCUS UBERIS ANTIGEN; STREPTOCOCCUS UBERIS VACCINE; STREPTOCOCCUS VACCINE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; BACTERIAL ANTIGEN;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ARTICLE; BACTERIAL STRAIN; BOVINE MASTITIS; CALF (BOVINE); CELLULAR IMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; CYTOTOXIC T LYMPHOCYTE; DAIRY CATTLE; DRUG SAFETY; DRUG TOLERABILITY; FLOW CYTOMETRY; GRANULOCYTE; HUMORAL IMMUNITY; IMMUNOGENICITY; LACTATION; MACROPHAGE; MILK; NEW ZEALAND; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; STREPTOCOCCUS UBERIS; VACCINATION; ANIMAL; BOVINAE; DAIRYING; FEMALE; GENETICS; IMMUNOLOGY; MASTITIS, BOVINE; METABOLISM; PHYSIOLOGY; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS; VETERINARY;

ANIMALIA; BOS; BOVINAE; STREPTOCOCCUS UBERIS;

ANIMALS; ANTIGENS, BACTERIAL; CATTLE; CYTOKINES; DAIRYING; FEMALE; MASTITIS, BOVINE; STREPTOCOCCAL INFECTIONS; STREPTOCOCCAL VACCINES; STREPTOCOCCUS; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84901608349     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2014.03.012     Document Type: Article

References (42)

1. Albenzio M., Santillo A., Caroprese M., Ruggieri D., Ciliberti M., Sevi A. Immune competence of the mammary gland as affected by somatic cell and pathogenic bacteria in ewes with subclinical mastitis. J. Dairy Sci. 2012, 95:3877-3887.
2. Almeida R.A., Fang W., Oliver S.P. Adherence and internalization of Streptococcus uberis to bovine mammary epithelial cells are mediated by host cell proteoglycans. FEMS Microbiol. Lett. 1999, 177:313-317.
3. Almeida R.A., Luther D.A., Oliver S.P. Incubation of Streptococcus uberis with extracellular matrix proteins enhances adherence to and internalization into bovine mammary epithelial cells. FEMS Microbiol. Lett. 1999, 178:81-85.
4. Almeida R.A., Luther D.A., Park H.M., Oliver S.P. Identification, isolation, and partial characterization of a novel Streptococcus uberis adhesion molecule (SUAM). Vet. Microbiol. 2006, 115:183-191.
5. Bannerman D.D., Paape M.J., Goff J.P., Kimura K., Lippolis J.D., Hope J.C. Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis. Vet. Res. 2004, 35:681-700.
6. Benjamin Y., Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Stat. Soc. Series B 1995, 57:289-300.
7. Chang B.S., Bohach G.A., Lee S.U., Davis W.C., Fox L.K., Ferens W.A., Seo K.S., Koo H.C., Kwon N.H., Park Y.H. Immunosuppression by T regulatory cells in cows infected with staphylococcal superantigen. J. Vet. Sci. 2005, 6:247-250.
8. Denis M., Parlane N.A., Lacy-Hulbert S.J., Summers E.L., Buddle B.M., Wedlock D.N. Bactericidal activity of macrophages against Streptococcus uberis is different in mammary gland secretions of lactating and drying off cows. Vet. Immunol. Immunopathol. 2006, 114:111-120.
9. Denis M., Wedlock D.N., Lacy-Hulbert J.S., Hillerton J.E., Buddle B.M. Vaccines against bovine mastitis in the New Zealand context: What is the best way forward?. NZ Vet. J. 2009, 57:132-140.
10. Denis M., Lacy-Hulbert S., Buddle B., Williamson J., Wedlock D. Streptococcus uberis specific T cells are present in mammary gland secretions of cows and can be activated to kill S. uberis. Vet. Res. Commun. 2011, 35:145-156.
11. Dranoff G., Jaffee E., Lazenby A., Golumbek P., Levitsky H., Brose K., Jackson V., Hamada H., Pardoll D., Mulligan R.C. Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity. Proc. Natl. Acad. Sci. U.S.A. 1993, 90:3539-3543.
12. Finch J.M., Winter A., Walton A.W., Leigh J.A. Further studies on the efficacy of a live vaccine against mastitis caused by Streptococcus uberis. Vaccine 1997, 15:1138-1143.
13. Fontaine M.C., Perez-Casal J., Song X.-M., Shelford J., Wilson P.J., Potter A.A. Immunization of dairy cattle with recombinant Streptococcus uberis GapC or a chimeric CAMP antigen conferes protection against heterologous bacterial challenge. Vaccine 2002, 20:2278-2286.
14. Harris J., Werling D., Koss M., Monaghan P., Taylor G., Howard C.J. Expression of caveolin by bovine lymphocytes and antigen-presenting cells. Immunology 2002, 105:190-195.
15. Hill A.W., Finch J.M., Field T.R., Leigh J.A. Immune modification of the pathogenesis of Streptococcus uberis mastitis in the dairy cow. FEMS Immunol. Med. Microbiol. 1994, 8:109-118.
16. Hogan J.S., Gonzalez R.N., Harmon R.J., Nickerson S.C., Oliver S.P., Pankey J.W., Smith K.L. National Mastitis Council Inc. 1999, Madison, Wisconsin.
17. Howard C.J., Naessens J. Summary of workshop findings for cattle (Tables 1 and 2). Vet. Immunol. Immunopathol. 1993, 39:25-47.
18. Kaur M., Saxena A., Rai A., Bhatnagar R. Rabies DNA vaccine encoding lysosome-targeted glycoprotein supplemented with Emulsigen-D confers complete protection in preexposure and postexposure studies in BALB/c mice. FASEB J. 2010, 24:173-183.
19. Kehrili M.E., Harp J.A. Immunity in the mammary gland. Vet. Clin. N. Am.: Food Anim. Pract. 2001, 17:495-516.
20. Lee J.W., O'Brien C.N., Guidry A.J., Paape M.J., Shafer-Weaver K.A., Zhao X. Effect of a trivalent vaccine against Staphylococcus aureus mastitis lymphocyte subpopulations, antibody production, and neutrophil phagocytosis. Can. J. Vet. Res. 2005, 69:11-18.
21. Leigh J.A., Finch J.M., Field T.R., Real N.C., Winter A., Walton A.W., Hodgkinson S.M. Vaccination with the plasminogen activator from Streptococcus uberis induces an inhibitory response and protects against experimental infection in the dairy cow. Vaccine 1999, 17:851-857.
22. Lopez-Benavides M.G., Williamson J.H., Pullinger G.D., Lacy-Hulbert S.J., Cursons R.T., Leigh J.A. Field observations on the variation of Streptococcus uberis populations in a pasture-based dairy farm. J. Dairy Sci. 2007, 90:5558-5566.
23. MacHugh N.D., Sopp P. Individual antigens of cattle, bovine CD8 (BoCD8). Vet. Immunol. Immunopathol. 1991, 27:65-69.
24. + T-cell trafficking in the primiparous bovine mammary gland. J. Dairy Sci. 2008, 91:193-201.
25. + T lymphocytes in the mammary gland of cows with Staphylococcus aureus mastitis. Vet. Immunol. Immunopathol. 1993, 36:137-151.
26. Pinheiro J., Bates D., DebRoy S., Sarkar D. nlme: Linear and Nonlinear Mixed Effects Models. R Package Version 3.1-101 2012, the R Development Core Team.
27. Prado M.E., Luther D.A., Lewis M.J., Headrick I.A., Almedia R.A., Oliver S.P. Vaccination with Streptococcus uberis adhesion molecule induces antibody responses in bovine serum and colostrum. Ann. Proc. Natl. Mastitis Committee 2008, 232-233.
28. Prado M.E., Almeida R.A., Ozen C., Luther D.A., Lewis M.J., Headrick S.J., Oliver S.P. Vaccination of dairy cows with recombinant Streptococcus uberis adhesion molecule induces antibodies that reduce adherence to and internalization of S. uberis into bovine mammary epithelial cells. Vet. Immunol. Immunopathol. 2011, 141:201-208.
29. Pullinger G.D., Lopez-Benavides M., Coffey T.J., Williamson J.H., Cursons R.T., Summers E., Lacy-Hulbert J., Maiden M.C., Leigh J.A. Application of Streptococcus uberis multilocus sequence typing: analysis of the population structure detected among environmental and bovine isolates from New Zealand and the United Kingdom. Appl. Environ. Microbiol. 2006, 72:1429-1436.
30. Reali E., Canter D., Zeytin H., Schlom J., Greiner J.W. Comparative studies of Avipox-GM-CSF versus recombinant GM-CSF protein as immune adjuvants with different vaccine platforms. Vaccine 2005, 23:2909-2921.
31. Riollet C., Rainard R., Poutrel B. Cell subpopulations and cytokine expression in cow milk in response to chronic Staphylococcus aureus infection. J. Dairy Sci. 2001, 84:1077-1084.
32. Shkreta L., Talbot B.G., Diarra M.S., Lacasse P. Immune responses to a DNA/protein vaccination strategy against Staphylococcus aureus induced mastitis in dairy cows. Vaccine 2004, 23:114-126.
33. Shu D., Subharat S., Wedlock D.N., Luo D., De Lisle G.W., Buddle B.M. Diverse cytokine profile from mesenteric lymph node cells of cull cows severely affected with Johne's disease. Clin. Vaccine Immunol. 2011, 18:1467-1476.
34. Snippe H., De Reuver M.J., Strickland F., Willers J.M., Hunter R.L. Adjuvant effect of nonionic block polymer surfactants in humoral and cellular immunity. Int. Arch. Allergy Appl. Immunol. 1981, 65:390-398.
35. Sopp P., Howard C.J. Cross-reactivity of monoclonal antibodies to defined human leucocyte differentiation antigens with bovine cells. Vet. Immunol. Immunopathol. 1997, 56:11-25.
36. Sordillo L.M., Kendall J.T., Corl C.M., Cross K.L. Molecular characterization of a saposin-like protein family member isolated from bovine lymphocytes. J. Dairy Sci. 2005, 88:1378-1390.
37. Subharat S., Shu D., de Lisle G.W., Buddle B.M., Wedlock D.N. Altered patterns of toll-like receptor gene expression in cull cows infected with Mycobacterium avium subsp. paratuberculosis. Vet. Immunol. Immunopathol. 2012, 145:471-478.
38. Tamilselvam B., Almeida R.A., Dunlap J.R., Oliver S.P. Streptococcus uberis internalizes and persists in bovine mammary epithelial cells. Microb. Pathog. 2006, 40:279-285.
39. +. Cell. Immunol. 1994, 156:245-253.
40. Wang Y.-Q., Zhang H.-H., Liu C.-L., Wu H., Wang P., Xia Q., Zhang L.-X., Li B., Wu J.-X., Yu B., Gu T.-J., Yu X.-H., Kong W. Enhancement of survivin-specific anti-tumor immunity by adenovirus prime protein-boost immunity strategy with DDA/MPL adjuvant in a murine melanoma model. Int. Immunopharmacol. 2013, 17:9-17.
41. Wedlock D.N., Denis M., Lacy-Hulbert J., Buddle B.M. Interleukin-1β infusion in bovine mammary glands prior to challenge with Streptococcus uberis reduces bacterial growth but causes sterile mastitis. Vet. Res. Commun. 2008, 32:439-447.
42. Young F.J., Woolliams J.A., Williams J.L., Glass E.J., O'Neill R.G., Fitzpatrick J.L. In vitro peripheral blood mononuclear cell proliferation in a crossbred cattle population. J. Dairy Sci. 2005, 88:2643-2651.