Vaccines against bovine mastitis in the New Zealand context: What is the best way forward?

New Zealand Veterinary Journal

Volumn 57, Issue 3, 2009, Pages 132-140

  Denis, M ^a   Wedlock, D N ^a   Lacy Hulbert, S J ^b   Hillerton, J E ^b   Buddle, B M ^a  

^a AGRESEARCH GRASSLANDS   (New Zealand)

^b DAIRYNZ   (New Zealand)

Author keywords

Cattle; Escherichia coli; Mastitis; Staphylococcus aureus; Streptococcus uberis; Vaccines

Indexed keywords

BACTERIAL VACCINE;

ANIMAL; CATTLE; CATTLE DISEASE; ESCHERICHIA COLI; FEMALE; IMMUNOLOGY; MICROBIOLOGY; NEW ZEALAND; REVIEW; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; UDDER; VACCINATION;

ANIMALS; BACTERIAL VACCINES; CATTLE; ESCHERICHIA COLI; FEMALE; MAMMARY GLANDS, ANIMAL; MASTITIS, BOVINE; NEW ZEALAND; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; VACCINATION;

ANIMALIA; BACTERIA (MICROORGANISMS); BOS; BOVINAE; ESCHERICHIA COLI; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS DYSGALACTIAE; STREPTOCOCCUS UBERIS;

EID: 68549115205     PISSN: 00480169     EISSN: 11760710     Source Type: Journal    
DOI: 10.1080/00480169.2009.36892     Document Type: Article

References (106)

1. Almeida RA, Oliver SP. Phagocytosis of Streptococcus uberis by bovine mammary macrophages: opsonizing effect of bovine antiserum. Zentralblatt für Veterinärmedizin B 42, 331–7, 1995
2. Almeida RA, Fang W, Oliver SP. Adherence and internalization of Streptococcus uberis to bovine mammary epithelial cells are mediated by host cell proteoglycans. FEMS Microbiology Letters 177, 313–7, 1999 a
3. Almeida RA, Luther DA, Oliver SP. Incubation of Streptococcus uberis with extracellular matrix proteins enhances adherence to and internalization into bovine mammary epithelial cells. FEMS Microbiology Letters 178, 81–5, 1999 b
4. Almeida RA, Luther DA, Park HM, Oliver SP. Identification, isolation, and partial characterization of a novel Streptococcus uberis adhesion molecule (SUAM). Veterinary Microbiology 115, 183–91, 2006
5. Anderson JC. The prospect of immunization against mastitis. Progress in the Control of Bovine Mastitis. Pp 524–7. Verlag, Gelsenkirchen-Buer, Germany, 1985
6. Anonymous. Seasonal Approach to Managing Mastitis. National Mastitis Advisory Committee, Wellington, NZ, 2005
7. Bannerman DD, Paape MJ, Goff JP, Kimura K, Lippolis JD, Hope JC. Innate immune response to intramammary infection with Serratia marcescens and Streptococcus uberis. Veterinary Research 35, 681–700, 2004
8. Barrio B, Vangroenweghe F, Dosogne H, Burvenich C. Decreased neutrophil bactericidal activity during phagocytosis of a slime-producing Staphylococcus aureus strain. Veterinary Research 31, 603–9, 2000
9. Barrio MB, Rainard P, Poutrel B. Milk complement and the opsonophagocytosis and killing of Staphylococcus aureus mastitis isolates by bovine neutrophils. Microbial Pathogenesis 34, 1–9, 2003
10. Bosworth BT, Dowbenko D, Shuster DE, Harp JA. Bovine L-selectin: a peripheral lymphocyte homing receptor. Veterinary Immunology and Immunopathology 37, 201–15, 1993
11. Brouillette E, Grondin G, Shkreta L, Lacasse P, Talbot BG. In vivo and in vitro demonstration that Staphylococcus aureus is an intracellular pathogen in the presence or absence of fibronectin-binding proteins. Microbial Pathogenesis 35, 159–68, 2003
12. Buescher ES. Anti-inflammatory characteristics of human milk: how, where, why. Advances in Experimental Medicine and Biology 501, 207–22, 2001
13. Burvenich C, Van Merris V, Mehrzad J, Diez-Fraile A, Duchateau L. Severity of E. coli mastitis is mainly determined by cow factors. Veterinary Research 34, 521–64, 2003
14. Chang Bs, Bohach GA, Lee SU, Davis WC, Fox LK, Ferens WA, Seo KS, Koo HC, Kwon NH, Park YH. Immunosuppression by T-regulatory cells in cows infected with staphylococcal superantigen. Journal of Veterinary Science 6, 247–50, 2005
15. Chockalingam A, McKinney CE, Rinaldi M, Zarlenga DS, Bannerman DD. A peptide derived from human bactericidal/permeability-increasing protein (BPI) exerts bactericidal activity against Gram-negative bacterial isolates obtained from clinical cases of bovine mastitis. Veterinary Microbiology 125, 80–90, 2007
16. Compton CWR, Cursons RTM, Barnett CME, McDougall S. Expression of innate resistance factors in mammary secretion from periparturient dairy heifers and their association with subsequent infection status. Veterinary Immunology andImmunopathology 127, 357–64, 2009
17. Denis M, Parlane NA, Lacy-Hulbert SJ, Summers EL, Buddle BB, Wedlock DN. Bactericidal activity of macrophages against Streptococcus uberis is different in mammary gland secretions of lactating and drying off cows. Veterinary Immunology and Immunopathology 114, 111–20, 2006
18. Dosogne H, Vangroenweghe F, Burvenich C. Potential mechanism of action of J5 vaccine in protection against severe bovine coliform mastitis. Veterinary Research 33, 1–12, 2002
19. Endsley JJ, Furrer JL, Endsley MA, McIntosh MA, Maue AC, Waters WR, Lee DR, Estes DM. Characterization of bovine homologues of granulysin and NK-lysin. Journal of Immunology 173, 2607–14, 2004
20. Field TR, Norton PM, Bland AP, Leigh JA. Changes in bovine neutrophils induced by the capsule of Streptococcus uberis. Advances in Experimental Medicine and Biology 418, 957–60, 1997
21. Field TR, Ward PN, Pedersen LH, Leigh JA. The hyaluronic acid capsule of Streptococcus uberis is not required for the development of infection and clinical mastitis. Infection and Immunity 71, 132–9, 2003
22. Finch JM, Hill AW, Field TR, Leigh JA. Local vaccination with killed Streptococcus uberis protects the bovine mammary gland against experimental intramammary challenge with the homologous strain. Infection and Immunity 62, 3599–603, 1994
23. Finch JM, Winter A, Walton AW, Leigh JA. Further studies on the efficacy of a live vaccine against mastitis caused by Streptococcus uberis. Vaccine 15, 1138–43, 1997
24. Fontaine MC, Perez-Casal J, Song X-M, Shelford J, Wilson PJ, Potter AA. Immunization of dairy cattle with recombinant Streptococcus uberis GapC or a chimeric CAMP antigen confers protection against heterologous bacterial challenge. Vaccine 20, 2278–86, 2002
25. Gill HS, Doull F, Rutherfurd KJ, Cross ML. Immunoregulatory peptides in bovine milk. British Journal of Nutrition 84 (Supplement 1), 111–7, 2000
26. Goldberg JJ, Pankey JW, Politis I, Zavizion B, Bramley AJ. Effect of oxygen tension on killing of Escherichia coli by bovine polymorphonuclear neutrophil leucocytes in vitro. Journal of Dairy Science 62, 331–8, 1995
27. Gonzalez RN, Cullor JS, Jasper DE, Farver TB, Bushnell RB, Oliver MN. Prevention of clinical coliform mastitis in dairy cows by a mutant Escherichia coli vaccine. Canadian Journal ofVeterinary Research 53, 301–5, 1989
28. Grant RG, Finch JM. Phagocytosis of Streptococcus uberis by bovine mammary gland macrophages. Research in Veterinary Science 62, 74–8, 1997
29. Groschup MH, Timoney JF. An R-like protein of Streptococcus uberis stimulates opsonising antibodies. Research in Veterinary Science 54, 124–6, 1993
30. Harp JA, Stabel JR, Pesch BA, Goff JP. Expression of adhesion molecules on milk and blood lymphocytes from periparturient dairy cattle with Johne’s disease. Veterinary Immunology and Immunopathology 98, 69–76, 2004 a
31. Harp JA, Waters TE, Goff JP. Lymphocyte subsets and adhesion molecule expression in milk and blood of periparturient dairy cattle. Veterinary Immunology and Immunopathology 102, 9–17, 2004 b
32. Harp JA, Waters TE, Goff JP, Bannerman DD, Paape MJ. Expression of lymphocyte homing and adhesion molecules during intramammary infection of cows with Serratia marcescens or Streptococcus uberis: correlation with bacterial colonization and clinical signs. Veterinary Immunology and Immunopathology 109, 13–21, 2006
33. Hébert A, Sayasith K, Sénéchal S, Dubreuil P, Lagacé J. Demonstration of intracellular Staphylococcus aureus in bovine mastitis alveolar cells and macrophages isolated from naturally infected cow milk. FEMS Microbiology Letters 193, 57–62, 2000
34. Hill AW. Protective effect of previous intramammary infection with Streptococcus uberis against subsequent clinical mastitis in the cow. Research in Veterinary Science 44, 386–7, 1988
35. Hill AW. Vaccination of cows with rough Escherichia coli mutants fails to protect against experimental intramammary bacterial challenge. Veterinary Research Communications 15, 7–16, 1991
36. Hill AW, Finch JM, Field TR, Leigh JA. Immune modification of the pathogenesis of Streptococcus uberis mastitis in the dairy cow. FEMS Immunology and Medical Microbiology 8, 109–17, 1994
37. Hodgkinson AJ, Carpenter EA, Smith CS, Molan PC, Prosser CG. Adhesion molecule expression in the bovine mammary gland. Veterinary Immunology and Immunopathology 115, 205–15, 2007
38. Hoedemaker M, Korff B, Edler B, Emmert M, Bleckmann E. Dynamics of Staphylococcus aureus infections during vaccination with an autogenous bacterin. Journal of Veterinary Medicine B. Infectious Diseases and Veterinary Public Health 48, 373–83, 2001
39. Hogan JS, Todhunter DA, Tomita GM, Smith KL, Schoenberger PS. Opsonic activity of bovine serum and mammary secretion after Escherichia coli J5 vaccination. Journal of Dairy Science 75, 72–7, 1992 a
40. Hogan JS, Smith KL, Todhunter DA, Schoenberger PS. Field trial to determine efficacy of an Escherichia coli J5 mastitis vaccine. Journal of Dairy Science 75, 78–84, 1992 b
41. Hogan JS, Weiss WP, Todhunter DA, Smith KL, Schoenberger PS. Efficacy of an Escherichia coli J5 mastitis vaccine in an experimental challenge trial. Journal of Dairy Science 75, 415–22, 1992 c
42. Howard P. Mastitis pathogens present in bulk tank milk from seven dairy herds in the Waikato region, New Zealand. New Zealand Veterinary Journal 54, 41–3, 2006
43. Hwang C-Y, Pak SI, Han H-R. Effects of autogenous toxoid-bacterin in lactating cows with Staphylococcus aureus subclinical mastitis. Journal of Veterinary Medical Science 62, 875–80, 2000
44. Jones CL, Monaghan P, Field TR, Smith AJ, Ward PN, Leigh JA. Localization of MtuA, an Lral homologue in Streptococcus uberis. Journal of Applied Microbiology 97, 149–57, 2004
45. Kehrli ME Jr, Harp JA. Immunity in the mammary gland. Veterinary Clinics of North America, Food Animal Practice 17, 495–516, 2001
46. Lascelles AK. The immune system on the ruminant mammary gland and its role in the control of mastitis. Journal of Dairy Science 62, 154–67, 1979
47. Lee JW, O’Brien CN, Guidry AJ, Paape MJ, Shafer-Weaver KA, Zhao × Effect of a trivalent vaccine against Staphylococcus aureus mastitis lymphocyte subpopulations, antibody production and neutrophil phagocytosis. Canadian Journal ofVeterinary Research 69, 11–18, 2001
48. Leigh JA. Streptococcus uberis: a permanent barrier to the control of bovine mastitis? Veterinary Journal 157, 225–38, 1999
49. Leigh JA. Vaccines against bovine mastitis due to Streptococcus uberis: current status and future prospects. Advances in Experimental Medicine and Biology 80, 307–11, 2000
50. Leigh JA. Re: ‘Immunization of dairy cattle with recombinant Streptococcus uberis GapC or a chimeric CAMP antigen confers protection against heterologous bacterial challenge’. MC Fontaine et al. (Vaccine 20, 2278–86, 2002). Vaccine 20, 3047–8, 2002
51. Leigh JA, Field TR. Streptococcus uberis resists the bactericidal action of bovine neutrophils despite the presence of bound immunoglobulin. Infection and Immunity 62, 1854–9, 1994
52. Leigh JA, Finch JM, Field TR, Real NC, Winter A, Walton AW, Hodgkinson SM. Vaccination with the plasminogen activator from Streptococcus uberis induces an inhibitory response and protects against experimental infection in the dairy cow. Vaccine 17, 851–7, 1999
53. Leitner G, Lubashevsky E, Glickman A, Winkler M, Saran A, Trainin Z. Development of a Staphylococcus aureus vaccine against mastitis in dairy cows 1. Challenge trials. Veterinary Immunology and Immunopathology 93, 31–8, 2003
54. Lopez-Benavides MG, Williamson JH, Pullinger GD, Lacy-Hulbert SJ, Cursons RT, Leigh JA. Field observations on the variation of Streptococcus uberis populations in a pasture-based dairy farm. Journal of Dairy Science 90, 5558–66, 2007
55. Lopez-Benavides MG, Williamson JH, Lacy-Hulbert SJ, Cursons RT. Heifer teats sprayed in the dry period with an iodine teat sanitizer have reduced Streptococcus uberis teat-end contamination and less Streptococcus uberis intramammary infections at calving. Veterinary Microbiology 134 (Special Issue: Heifer and CNS Mastitis), 186–91, 2009
56. Malcolm D. The costs of mastitis revisited in a boom year. Annual Proceedings of the National Mastitis Advisory Committee. Pp 136–7, 2007
57. Mayer SJ, Waterman AE, Keen PM, Craven N, Bourne FJ. Oxygen concentration in milk of healthy and mastitic cows and implications of low oxygen tension for the killing of Staphylococcus aureus by bovine neutrophils. Journal of Dairy Science 55, 513–9, 1988
58. McDougall S. Management factors associated with the incidence of clinical mastitis over the non-lactation period and bulk tank somatic cell count during the subsequent lactation. New Zealand Veterinary Journal 51, 63–72, 2003
59. McDougall S, Arthur DG, Bryan MA, Vermunt JJ, Weir AM. Clinical and bacteriological response to treatment of clinical mastitis with one of three intramammary antibiotics. New Zealand Veterinary Journal 55, 161–70, 2007
60. McDougall S, Parker KI, Heuer C, Compton CWR. A review of prevention and control of heifer mastitis via non-antibiotic strategies. Veterinary Microbiology 134 (Special Issue: Heifer and CNS Mastitis), 177–85, 2009
61. Mehrzad J, Dosogne H, Meyer E, Heyneman R, Burvenich C. Respiratory burst activity of blood and milk neutrophils in dairy cows during different stages of lactation. Journal of Dairy Science 68, 399–415, 2001
62. Mehrzad J, Janssen D, Duchateau L, Burvenich C. Increase in Escherichia coli inoculum dose accelerates CD8+ T-cell trafficking in the primiparous bovine mammary gland. Journal of Dairy Science 91, 193–201, 2008
63. Mellenberger RW. Vaccination against mastitis. Journal of Dairy Science 60, 1016–21, 1977
64. Middleton JR, Ma J, Rinehart CL, Taylor VN, Luby CD, Steevens BJ. Efficacy of different Lysigin formulations in the prevention of Staphylococcus aureus intramammary infection in dairy heifers. Journal of Dairy Research 73, 10–19, 2006
65. Musser JM, Anderson KL. Effect of vaccination with an Escherichia coli bacterin- toxoid on milk production in dairy cattle. Journal of the American Veterinary Medical Association 209, 1291–3, 1996
66. Nickerson SC, Owens WE, Boddie RL. Effect of a Staphylococcus aureus bacterin on serum antibody, new infection, and mammary histology in nonlactating dairy cows. Journal ofDairy Science 76, 1290–7, 1993
67. Pankey JW, Boddie NT, Watts JL, Nickerson SC. Evaluation of protein A and a commercial bacterin as vaccines against Staphylococcus aureus mastitis by experimental challenge. Journal of Dairy Science 68, 726–31, 1985
68. Park YH, Fox LK, Hamilton MJ, Davis WC. Suppression of proliferative response of BoCD4+ T lymphocytes by activated BoCD8+ T lymphocytes in the mammary gland of cows with Staphylococcus aureus mastitis. Veterinary Immunology and Immunopathology 36, 137–51, 1993
69. Politis I, Zhao X, McBride BW, Burton JH. Function of bovine mammary macrophages as antigen-presenting cells. Veterinary Immunology and Immunopathology 30, 399–410, 1992
70. Prado ME, Luther DA, Lewis MJ, Headrick IA, Almeida RA, Oliver SP. Vaccination with Streptococcus uberis adhesion molecule induces antibody responses in bovine serum and colostrum. Annual Proceedings of the National Mastitis Committee. Pp 232–3, 2008
71. Pullinger GD, Lopez-Benavides M, Coffey TJ, Williamson JH, Cursons RT, Summers E, Lacy-Hulbert J, Maiden MC, Leigh JA. Application of Streptococcus uberis multilocus sequence typing: analysis of the population structure detected among environmental and bovine isolates from New Zealand and the United Kingdom. Applied and Environmental Microbiology 72, 1429–36, 2006
72. Rainard P. Bacteriostatic activity of bovine milk lactoferrin against mastitic bacteria. Veterinary Microbiology 11, 387–92, 1986
73. Rainard P. The complement in milk and defence of the bovine mammary gland against infections. Veterinary Research 34, 647–70, 2003
74. Riollet C, Rainard P, Poutrel B. Cells and cytokines in inflammatory secretions of bovine mammary gland. Advances in Experimental Medicine and Biology 480, 247–58, 2000
75. Riollet C, Rainard P, Poutrel B. Cell subpopulations and cytokine expression in cow milk in response to chronic Staphylococcus aureus infection. Journal of Dairy Science 84, 1077–84, 2001
76. Rivas AL, Schwager SJ, Gonzalez RN, Quimby FW Anderson KL. Multifactorial relationships between intramammary invasion by Staphylococcus aureus and bovine leukocyte markers. Canadian Journal of Veterinary Research 71, 135–44, 2007
77. Schmitt-Van de Leemput E, Zadoks RN. Genotypic and phenotypic detection of macrolide and lincosamide resistance in Streptococcus uberis. Journal of Dairy Science 90, 5089–96, 2007
78. Schwertfeger KL, Rosen JM, Cohen DA. Mammary gland macrophages: pleiotropic functions in mammary development. Journal of Mammary Gland Biology and Neoplasia 11, 229–38, 2006
79. Seegers H, Fourichon C, Beaudeau F. Production effects related to mastitis and mastitis economics in dairy cattle herds. Veterinary Research 34, 475–91, 2003
80. Shkreta L, Talbot BG, Diarra MS, Lacasse P. Immune responses to a DNA/protein vaccination strategy in dairy cows. Vaccine 23, 114–26, 2004
81. Smith AJ, Ward PN, Field TR, Jones CL, Lincoln RA, Leigh JA. MtuA, a lipoprotein receptor antigen from Streptococcus uberis, is responsible for acquisition of manganese during growth in milk and is essential for infection of the lactating bovine mammary gland. Infection and Immunity 71, 4842–9, 2003
82. Smith JL, Hogan JS, Smith KL. Efficacy of intramammary immunization with an Escherichia coli J5 bacterin. Journal of Dairy Science 82, 2582–8, 1999
83. Sordillo LM, Kendall JT, Corl CM, Cross TH. Molecular characterization of a saposin-like protein family member isolated from bovine lymphocytes. Journal of Dairy Science 88, 1378–90, 2005
84. Takemura K, Hogan JS, Lin J, Smith KL. Efficacy of immunization with ferric citrate receptor FecA from Escherichia coli on induced coliform mastitis. Journal of Dairy Science 85, 774–81, 2002
85. Tamilselvam B, Almeida RA, Dunlap JR, Oliver SP. Streptococcus uberis internalizes and persists in bovine mammary epithelial cells. Microbial Pathogenesis 40, 279–85, 2006
86. Tatarczuch L, Philip C, Bischof R, Lee CS. Leucocyte phenotypes in involuting and fully involuted mammary glandular tissues and secretions of sheep. Journal of Anatomy 196, 313–26, 2000
87. Tatarczuch L, Bischof RJ, Philip CJ, Lee CS. Phagocytic capacity of leucocytes in sheep mammary secretions following weaning. Journal of Anatomy 201, 351–61, 2002
88. Taylor BC, Dellinger JD, Cullor JS, Stott JL. Bovine milk lymphocytes display the phenotype of memory T cells and are predominantly CD8+. Cellular Immunology 156, 245–53, 1994
89. Tenhagen BA, Edinger D, Baumgartner B, Kalbe P, Klunder G, Heuwieser W. Efficacy of a herd-specific vaccine against Staphylococcus aureus to prevent postpartum mastitis in dairy heifers. Journal of Veterinary Medicine A. Physiology, Pathology, Clinical Medicine 48, 601–7, 2001
90. Thomas LH, Haider W Hill AW Cook RS. Pathologic findings of experimentally induced Streptococcus uberis infection in the mammary gland of cows. American Journal ofVeterinary Research 55, 1723–8, 1994
91. Tomita GM, Nickerson SC, Owens WE, Wren B. Influence of route of vaccine administration against experimental intramammary infection caused by Escherichia coli. Journal ofDairy Science 81, 2159–64, 1998
92. Ward PN, Field TR, Rapier CD, Leigh JA. The activation of bovine plasminogen by PauA is not required for virulence of Streptococcus uberis. Infection and Immunity 71, 7193–6, 2003
93. Watson DL. Evaluation of attenuated, live staphylococcal mastitis vaccine in lactating heifers. Journal of Dairy Science 67, 2608–13, 1984
94. Watson DL. Vaccination against experimental staphylococcal mastitis in ewes. Research in Veterinary Science45, 16–21, 1988
95. Watson DL, Kennedy JW. Immunisation against experimental staphylococcal mastitis in sheep- effect of challenge with a heterologous strain of Staphylococcus aureus. Australian Veterinary Journal 57, 309–13, 1981
96. Watson DL, Lee CG. Immunity to experimental staphylococcal mastitis-comparison of live and killed vaccines. Australian Veterinary Journal 54, 374–8, 1978
97. Wedlock DN, Denis M, Buddle BM. Can Vaccines Offer a Solution to Mastitis? Immunet Meeting, Wellington, NZ, 2007
98. Wedlock, DN, Denis M, Lacy-Hulbert SJ, Buddle BM. Interleukin-1 infusion in bovine mammary glands prior to challenge with Streptococcus uberis reduces bacterial growth but causes sterile mastitis. Veterinary Research Communications 32, 439–47, 2008
99. Wheeler TT, Hodgkinson AJ, Prosser CG, Davis SR. Immune components of colostrum and milk- A historical perspective. Journal of Mammary Gland Biology and Neoplasia 12, 237–47, 2007
100. Williams, JM, Shipley GR, Smith GL, Gerber DL. A clinical evaluation of Staphylococcus aureus bacterin in the control of staphylococcal mastitis in cows. Veterinary Medicine, Small Animal Clinician 70, 587–94, 1975
101. Wilson DJ, Grohn YT, Bennett GJ, Gonzalez RN, Schukken YH, Spatz J. Milk production change following clinical mastitis and reproductive performance compared among J5 vaccinated and control dairy cattle. Journal of Dairy Science 91, 3869–79, 2008
102. Wbolford MW, Hook IJ, Eden MT, Joe AK. The SAMM plan, a seasonal approach to managing mastitis. Proceedings of the Third IDF International Mastitis Seminar. Supplement 4. Pp 59–63, 1995
103. Wbolford MW, Williamson JH, Day AM, Copeman PJ. The prophylactic effect of a teat sealer on bovine mastitis during the dry period and the following lactation. New Zealand Veterinary Journal 46, 12–19, 1998
104. Yancey RJ. Recent advances in bovine vaccine technology. Journal of Dairy Science 76, 2418–36, 1993
105. Yancey RJ. Vaccines and diagnostic methods for bovine mastitis: fact and fiction. Advances in Veterinary Medicine 41, 257–73, 1999
106. Yoshida K, Ichiman Y, Narikawa S, Evans WB. Staphylococcal capsular vaccine for preventing mastitis in two herds in Georgia. Journal of Dairy Science 67, 620–7, 1984