Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation

British Journal of Cancer

Volumn 110, Issue 11, 2014, Pages 2747-2755

  Van Miltenburg, M H A M ^a,b   Van Nimwegen, M J ^a   Tijdens, I ^a   Lalai, R ^a   Kuiper, R ^c   Klarenbeek, S ^b   Schouten, P C ^b   De Vries, A ^d   Jonkers, J ^b   Van De Water, B ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

FAK; mammary gland; mammary tumour; p53; proliferation

Indexed keywords

FOCAL ADHESION KINASE; PROTEIN P53;

ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BREAST EPITHELIUM; BREAST TUMOR; CELL PROLIFERATION; FEMALE; GENE DELETION; GENE EXPRESSION; GENE INACTIVATION; GENOTYPE; LOXP SITE; MAMMARY GLAND; MOUSE; NONHUMAN; ONCOGENE; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TUMOR CELL; TUMOR GROWTH; TUMOR SUPPRESSOR GENE;

ANIMALS; CARCINOGENESIS; CARCINOMA; CARCINOSARCOMA; CELL PROLIFERATION; EPITHELIAL CELLS; FEMALE; FOCAL ADHESION KINASE 1; HUMANS; INCIDENCE; MAMMARY GLANDS, ANIMAL; MAMMARY NEOPLASMS, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MUTATION, MISSENSE; TUMOR BURDEN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84901602604     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2014.219     Document Type: Article

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