Complete focal adhesion kinase deficiency in the mammary gland causes ductal dilation and aberrant branching morphogenesis through defects in Rho kinase-dependent cell contractility

FASEB Journal

Volumn 23, Issue 10, 2009, Pages 3482-3493

  Van Miltenburg, Martine H A M ^a   Lalai, Reshma ^a   De Bont, Hans ^a   Van Waaij, Eveline ^a   Beggs, Hilary ^b   Danen, Erik H J ^a   Van De Water, Bob ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Adhesion signaling; Lactation; Luminal epithelial cells; Myoepithelial cells

Indexed keywords

CRE RECOMBINASE; FAT; FOCAL ADHESION KINASE; RHO KINASE;

ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BREAST CELL; BREAST DEVELOPMENT; BREAST DUCT; BREAST EPITHELIUM; CELL CONTRACTILITY; CELL FUNCTION; CELL LOSS; CONTROLLED STUDY; GENE DELETION; IMMUNE DEFICIENCY; KNOCKOUT GENE; MAMMARY GLAND; MORPHOGENESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TISSUE DIFFERENTIATION;

ANIMALS; EPITHELIAL CELLS; FEMALE; FOCAL ADHESION KINASE 1; GENE DELETION; LACTATION; MAMMARY GLANDS, ANIMAL; MICE; MICE, KNOCKOUT; MORPHOGENESIS; PREGNANCY; RHO-ASSOCIATED KINASES;

MUS;

EID: 70349659018     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.08-123398     Document Type: Article

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